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1. Full Text Nrf2 is controlled by two distinct β-TrCP recognition motifs in its Neh6 domain, one of which can be modulated by GSK-3 activity
by Chowdhry, S and Zhang, Y and McMahon, M and Sutherland, C and Cuadrado, A and Hayes, J.D
Oncogene, ISSN 0950-9232, 08/2013, Volume 32, Issue 32, pp. 3765 - 3781
Identification of regulatable mechanisms by which transcription factor NF-E2 p45-related factor 2 (Nrf2) is repressed will allow strategies to be designed that... 
b-TrCP | GSK-3 | drug resistance | Nrf2 | ubiquitylation | oxidative stress | PROTEASOMAL DEGRADATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | GLYCOGEN-SYNTHASE KINASE-3 | MAP KINASES | beta-TrCP | CELL BIOLOGY | E3 LIGASE | TRANSCRIPTION FACTOR NRF2 | ANTIOXIDANT RESPONSE ELEMENT | ONCOLOGY | NEGATIVE REGULATION | GENETICS & HEREDITY | HEME OXYGENASE-1 | KEAP1 GENE | NF-E2-Related Factor 2 - physiology | Protein Structure, Tertiary | Phosphorylation | p38 Mitogen-Activated Protein Kinases - physiology | Humans | Glycogen Synthase Kinase 3 - metabolism | beta-Transducin Repeat-Containing Proteins - chemistry | NF-E2-Related Factor 2 - analysis | Ubiquitination | beta-Transducin Repeat-Containing Proteins - metabolism | Animals | Phosphatidylinositol 3-Kinases - physiology | Antineoplastic Agents - pharmacology | Mice | NF-E2-Related Factor 2 - chemistry | Extracellular Signal-Regulated MAP Kinases - physiology | Intracellular Signaling Peptides and Proteins - physiology | Binding Sites | Kelch-Like ECH-Associated Protein 1 | β-TrCP
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2. Full Text Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1
by Malhotra, Deepti and Thimmulappa, Rajesh and Navas-Acien, Ana and Sandford, Andrew and Elliott, Mark and Singh, Anju and Chen, Linan and Zhuang, Xiaoxi and Hogg, James and Pare, Peter and Tuder, Rubin M and Biswal, Shyam
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 09/2008, Volume 178, Issue 6, pp. 592 - 604
Rationale Oxidative stress is a key contributor in chronic obstructive pulmonary disease (COPD) pathogenesis caused by cigarette smoking. NRF2, a... 
Antioxidants | Oxidative stress | Chronic obstructive pulmonary disease | DJ-1 | NRF2 | NRF2 ENHANCES SUSCEPTIBILITY | OXIDATIVE DAMAGE | antioxidants | INDUCED INFLAMMATORY RESPONSE | AIRWAY INFLAMMATION | HEME OXYGENASE-1 GENE | CHEMOPREVENTIVE AGENT SULFORAPHANE | GAMMA-GLUTAMYLCYSTEINE SYNTHETASE | TRANSCRIPTION FACTOR NRF2 | EPITHELIAL-CELLS | RESPIRATORY SYSTEM | CIGARETTE-SMOKE | oxidative stress | chronic obstructive pulmonary disease | CRITICAL CARE MEDICINE | NF-E2-Related Factor 2 - physiology | Glutathione - metabolism | Humans | Middle Aged | Oxidative Stress - physiology | Lung - chemistry | Male | Pulmonary Disease, Chronic Obstructive - physiopathology | Oncogene Proteins - physiology | Smoking - physiopathology | Female | Thiobarbituric Acid Reactive Substances - analysis | Pulmonary Disease, Chronic Obstructive - metabolism | Antioxidants - analysis | Cells, Cultured | Epithelial Cells | Mice, Inbred Strains | Protein Deglycase DJ-1 | Smoking - metabolism | NF-E2-Related Factor 2 - analysis | Animals | Signal Transduction - physiology | Mice | NAD(P)H Dehydrogenase (Quinone) - analysis | Oxidative Stress - drug effects | Intracellular Signaling Peptides and Proteins - physiology | Lipid Peroxidation | B. Chronic Obstructive Pulmonary Disease
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3. Full Text Non-thermal plasma activates human keratinocytes by stimulation of antioxidant and phase II pathways
by Schmidt, Anke and Dietrich, Stephan and Steuer, Anna and Weltmann, Klaus-Dieter and Von Woedtke, Thomas and Masur, Kai and Wende, Kristian
Journal of Biological Chemistry, ISSN 0021-9258, 03/2015, Volume 290, Issue 11, pp. 6731 - 6750
Non-thermal atmospheric pressure plasma provides a novel therapeutic opportunity to control redox-based processes, e.g. wound healing, cancer, and inflammatory... 
OXIDATIVE STRESS | IN-VITRO | REDOX REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR EXPORT | HACAT KERATINOCYTES | HEME OXYGENASE-1 | C-JUN | GROWTH-FACTOR SYNTHESIS | TRANSCRIPTIONAL REPRESSOR | ATMOSPHERIC-PRESSURE PLASMA | Cell Line | Cell Survival - drug effects | RNA, Small Interfering - genetics | Heme Oxygenase-1 - metabolism | Reactive Oxygen Species - metabolism | Glutathione - metabolism | Reactive Nitrogen Species - metabolism | Antioxidants - metabolism | Humans | Keratinocytes - cytology | Transcriptome - drug effects | Plasma Gases - pharmacology | Heme Oxygenase-1 - genetics | NF-E2-Related Factor 2 - analysis | Keratinocytes - drug effects | Signal Transduction - drug effects | Keratinocytes - metabolism | NF-E2-Related Factor 2 - metabolism | Oxidation-Reduction - drug effects | NF-E2-Related Factor 2 - genetics | Oxidative Stress - drug effects | Keratinocyte | Gene Expression | Reactive Oxygen Species (ROS) | Oxidative Stress | Reactive Nitrogen Species (RNS) | Cell Biology
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4. Full Text Nuclear factor erythroid 2-related factors 1 and 2 are able to define the worst prognosis group among high-risk diffuse large B cell lymphomas treated with R-CHOEP
by Kari, Esa and Teppo, Hanna-Riikka and Haapasaari, Kirsi-Maria and Kuusisto, Milla Elvi Linnea and Lemma, Aurora and Karihtala, Peeter and Pirinen, Risto and Soini, Ylermi and Jantunen, Esa and Turpeenniemi-Hujanen, Taina and Kuittinen, Outi
Journal of Clinical Pathology, ISSN 0021-9746, 04/2019, Volume 72, Issue 4, pp. 316 - 321
AimsOxidative stress markers and antioxidant enzymes have previously been shown to have prognostic value and associate with adverse outcome in patients with... 
nrf2 | diffuse large B-cell lymphoma | keap1 | nrf1 | bach1 | KEAP1 | OXIDATIVE STRESS | ACTIVATION | PATHOLOGY | NRF2 INHIBITOR | EXPRESSION | Immunohistochemistry | Antineoplastic Agents, Immunological - administration & dosage | Predictive Value of Tests | Prednisolone - adverse effects | Cyclophosphamide - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Prednisolone - administration & dosage | Humans | Middle Aged | Antineoplastic Combined Chemotherapy Protocols - adverse effects | Male | Cyclophosphamide - adverse effects | Cytoplasm - pathology | Young Adult | Cell Nucleus - pathology | Lymphoma, Large B-Cell, Diffuse - chemistry | Vincristine - administration & dosage | Adult | Female | Retrospective Studies | Doxorubicin - administration & dosage | Rituximab - adverse effects | Cytoplasm - chemistry | Etoposide - adverse effects | Lymphoma, Large B-Cell, Diffuse - drug therapy | Lymphoma, Large B-Cell, Diffuse - pathology | NF-E2-Related Factor 1 - analysis | Risk Assessment | Biomarkers, Tumor - analysis | Risk Factors | Etoposide - administration & dosage | Treatment Outcome | Kelch-Like ECH-Associated Protein 1 - analysis | Lymphoma, Large B-Cell, Diffuse - mortality | Rituximab - administration & dosage | Antineoplastic Agents, Immunological - adverse effects | Basic-Leucine Zipper Transcription Factors - analysis | NF-E2-Related Factor 2 - analysis | Vincristine - adverse effects | Aged | Cell Nucleus - chemistry | Neoplasm Staging | Doxorubicin - adverse effects | Medical research | Enzymes | Oxidative stress | Transcription factors | Disease | Lung cancer | Colorectal cancer | Nervous system | Metastasis | Gene expression | Patients | Cancer therapies | Antioxidants | Proteins | Survival analysis | Hospitals | Medical prognosis | Epigenetics | Lymphomas | Original | 1506
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5. Full Text SQSTM1 Is a Pathogenic Target of 5q Copy Number Gains in Kidney Cancer
by Li, Lianjie and Shen, Chuan and Nakamura, Eijiro and Ando, Kiyohiro and Signoretti, Sabina and Beroukhim, Rameen and Cowley, Glenn S and Lizotte, Patrick and Liberzon, Ella and Bair, Steven and Root, David E and Tamayo, Pablo and Tsherniak, Aviad and Cheng, Su-Chun and Tabak, Barbara and Jacobsen, Anders and Hakimi, A. Ari and Schultz, Nikolaus and Ciriello, Giovanni and Sander, Chris and Hsieh, James J and Kaelin, William G
Cancer Cell, ISSN 1535-6108, 12/2013, Volume 24, Issue 6, pp. 738 - 750
Clear cell renal cell carcinoma (ccRCC) is the most common form of kidney cancer and is often linked to loss of chromosome 3p, which harbors the tumor... 
BETA-DOMAIN | TRANSCRIPTION FACTOR NRF2 | LINDAU GENE-PRODUCT | ONCOLOGY | TUMOR-SUPPRESSOR PROTEIN | AUTOPHAGY | IDENTIFICATION | P62 | TUMORIGENESIS | RENAL-CELL CARCINOMA | P62/SEQUESTOSOME 1 | CELL BIOLOGY | NF-E2-Related Factor 2 - physiology | Kidney Neoplasms - genetics | Sequestosome-1 Protein | Humans | Carcinoma, Renal Cell - genetics | Molecular Sequence Data | Gene Dosage | Chromosomes, Human, Pair 5 | Adaptor Proteins, Signal Transducing - physiology | NF-E2-Related Factor 2 - analysis | Animals | Base Sequence | Adaptor Proteins, Signal Transducing - genetics | Cell Line, Tumor | Mice | Medical colleges | Genes | Kidney cancer | Cancer
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6. Full Text Effects of Calcium Silicate Endodontic Cements on Biocompatibility and Mineralization-inducing Potentials in Human Dental Pulp Cells
by Chang, Seok-Woo, DDS, PhD and Lee, So-Youn, MSD and Ann, Hyo-Jung, DDS, PhD and Kum, Kee-Yeon, DDS, PhD and Kim, Eun-Cheol, DDS, PhD
Journal of Endodontics, ISSN 0099-2399, 2014, Volume 40, Issue 8, pp. 1194 - 1200
Abstract Introduction The objective of this study was to evaluate the biocompatibility, inflammatory response, and odontoblastic potential of Biodentine... 
Endocrinology & Metabolism | Dentistry | Biodentine | nuclear factor–E2-related factor-2 | dental pulp cells | odontoblastic potential | inflammatory response | Biocompatibility | heme oxygenase-1 | nuclear factor-E2-related factor-2 | nuclear factor E2-related factor-2 | PROLIFERATION | TRIOXIDE AGGREGATE | HEAT-STRESS | ODONTOBLASTIC DIFFERENTIATION | MATRIX METALLOPROTEINASES | IN-VITRO | CLINICAL-APPLICATIONS | DENTISTRY, ORAL SURGERY & MEDICINE | GENE-EXPRESSION | END-FILLING MATERIALS | Dinoprostone - analysis | Cytokines - analysis | Humans | Dental Cements - pharmacology | Nitric Oxide - analysis | Nitric Oxide Synthase Type II - analysis | Inflammation Mediators - analysis | Mitogen-Activated Protein Kinases - analysis | Alkaline Phosphatase - analysis | Pulp Capping and Pulpectomy Agents - pharmacology | Calcium Compounds - pharmacology | Silicates - pharmacology | Calcification, Physiologic - drug effects | Dental Pulp - cytology | Dental Pulp - drug effects | Materials Testing | Biocompatible Materials - pharmacology | Zinc Oxide-Eugenol Cement - pharmacology | Cyclooxygenase 2 - analysis | Reactive Oxygen Species - analysis | Oxides - pharmacology | NF-E2-Related Factor 2 - analysis | Heme Oxygenase-1 - analysis | Signal Transduction - drug effects | Cell Differentiation - drug effects | Methylmethacrylates - pharmacology | Odontoblasts - drug effects | Bismuth - pharmacology | Root Canal Filling Materials - pharmacology | Aluminum Compounds - pharmacology | Cell Proliferation - drug effects | Drug Combinations
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7. Full Text High NRF2 expression controls endoplasmic reticulum stress induced apoptosis in multiple myeloma
by Sun, Yu and Abdul Aziz, Amina and Bowles, Kristian and Rushworth, Stuart
Cancer Letters, ISSN 0304-3835, 01/2018, Volume 412, pp. 37 - 45
Multiple myeloma (MM) is an incurable disease characterized by clonal plasma cell proliferation. The stress response transcription factor Nuclear factor... 
Oxidative stress | NRF2 or nuclear factor erythroid 2 [NF-E2]-related factor 2 | Endoplasmic reticulum | Multiple myeloma | CELLS | ACTIVATION | REDOX HOMEOSTASIS | BORTEZOMIB | HUMAN MONOCYTES | UNFOLDED PROTEIN RESPONSE | ONCOLOGY | RESISTANCE | LEUKEMIA | PROTEASOME INHIBITORS | CYTOTOXICITY | NF-E2-Related Factor 2 - physiology | NF-E2-Related Factor 2 - antagonists & inhibitors | Proteasome Inhibitors - pharmacology | Glutathione - metabolism | Humans | Transcription Factor CHOP - analysis | Multiple Myeloma - metabolism | Multiple Myeloma - drug therapy | Multiple Myeloma - pathology | NF-E2-Related Factor 2 - analysis | Cell Line, Tumor | Apoptosis | Endoplasmic Reticulum Stress - physiology | Antioxidants | Medical colleges | Protein binding | Cell proliferation | Biotechnology | Reactive oxygen species | Physiological effects | Transcription factors | Homeostasis | Homology | CCAAT/enhancer-binding protein | Drug resistance | Cancer therapies | Proteins | Cell growth | Penicillin | Drug metabolism | Bone marrow | Inhibition | Stresses | Cell survival | Manufacturers | Metabolism | Gene expression | Survival | Proteasome inhibitors | Chemotherapy | Cell lines | Viability | Tumors
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8. Full Text Bioavailable Blueberry‐Derived Phenolic Acids at Physiological Concentrations Enhance Nrf2‐Regulated Antioxidant Responses in Human Vascular Endothelial Cells
by Tang, Jeffry S and Vissers, Margreet C. M and Anderson, Robert F and Sreebhavan, Sreevalsan and Bozonet, Stephanie M and Scheepens, Arjan and Melton, Laurence D
Molecular Nutrition & Food Research, ISSN 1613-4125, 03/2018, Volume 62, Issue 5, pp. 1700647 - n/a
Scope Blueberry consumption is believed to confer a cardiovascular health advantage, but the active compounds and effects require characterization. This study... 
bioavailability | nuclear factor erythroid 2‐related factor | vascular effects | blueberries | phenolic acids | nuclear factor erythroid 2-related factor | METABOLITES | ACTIVATION | FOOD SCIENCE & TECHNOLOGY | ANTHOCYANINS | BLOOD-PRESSURE | CONTROLLED CLINICAL-TRIAL | WILD BLUEBERRY | ARTERIAL STIFFNESS | DOUBLE-BLIND | (POLY)PHENOLS | HYDROGEN-PEROXIDE | NF-E2-Related Factor 2 - physiology | Cell Survival - drug effects | Hydroxybenzoates - pharmacology | NF-E2-Related Factor 2 - analysis | Heme Oxygenase-1 - analysis | Humans | Blueberry Plants - chemistry | Cells, Cultured | Fruit and Vegetable Juices - analysis | Heme Oxygenase-1 - physiology | Antioxidants - pharmacology | Endothelial Cells - drug effects | Antioxidants | Cysteine | Metabolites | Ligases | Heme | Physiological aspects | Glutamate | Gene expression | Endothelium | Translocation | Hydrogen peroxide | Bioavailability | Phenolic acids | Biological activity | Nuclear transport | Endothelial cells | Proteins | Oxygenase | Acids | Phenols | Pretreatment | Human behavior | Blueberries
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9. Full Text Allicin decreases lipopolysaccharide-induced oxidative stress and inflammation in human umbilical vein endothelial cells through suppression of mitochondrial dysfunction and activation of Nrf2
by Zhang, Min and Pan, Huichao and Xu, Yinjie and Wang, Xueting and Qiu, Zhaohui and Jiang, Li
Cellular Physiology and Biochemistry, ISSN 1015-8987, 06/2017, Volume 41, Issue 6, pp. 2255 - 2267
Background: Allicin, a major component of garlic, is regarded as a cardioprotective agent and is associated with increased endothelial function. Methods: The... 
HUVEC | Inflammation | Allicin | Mitochondrial dysfunction | Nrf2 | Atherosclerosis | CANCER-CELLS | APOPTOSIS | PHYSIOLOGY | RISK-FACTORS | FENOFIBRATE | BLOOD-PRESSURE | GARLIC POWDER | HIGH GLUCOSE | THERAPEUTIC TARGETS | GENERATION | Human Umbilical Vein Endothelial Cells | Inflammation - pathology | Neutrophils - cytology | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Liver X Receptors - antagonists & inhibitors | Humans | Sulfinic Acids - pharmacology | Membrane Potential, Mitochondrial - drug effects | RNA Interference | Lipid Peroxidation - drug effects | Neutrophils - metabolism | Malondialdehyde - metabolism | Lipopolysaccharides - toxicity | Cytochromes c - metabolism | Liver X Receptors - metabolism | Mitochondria - metabolism | Mitochondria - drug effects | Cell Adhesion - drug effects | Interleukin-8 - analysis | Tumor Necrosis Factor-alpha - analysis | NF-E2-Related Factor 2 - analysis | NF-E2-Related Factor 2 - metabolism | Oxidative Stress - drug effects | Liver X Receptors - genetics | Antioxidants | Studies | Oxidative stress | Rodents | Cytotoxicity | Gene expression | Veins & arteries | Apoptosis | Cell adhesion & migration
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10. Protective role of nuclear factor erythroid 2-related factor 2 in the hemorrhagic shock-induced inflammatory response
by Zhao, HG and Hao, SJ and Xu, HF and Ma, L and Zhang, Z and Ni, YM and Yu, LY
INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE, ISSN 1107-3756, 04/2016, Volume 37, Issue 4, pp. 1014 - 1022
Hemorrhagic shock (HS) following trauma or major surgery significantly contributes to mortality. However, the mechanisms through which HS activates the... 
MEDICINE, RESEARCH & EXPERIMENTAL | NRF2 ENHANCES SUSCEPTIBILITY | OXIDATIVE STRESS | NEUTROPHIL ACTIVATION | hemorrhagic shock | inflammatory response | ACUTE LUNG INJURY | HEPATIC-INJURY | ischemia/reperfusion | CYTOKINE PRODUCTION | PATHWAY | nuclear factor-erythroid 2 p45 subunit-related factor 2 | MICE | pro-inflammatory cytokine | EXPRESSION | RESUSCITATION | Inflammation - pathology | Leukocytes - pathology | Up-Regulation | Liver - pathology | Shock, Hemorrhagic - complications | Humans | Macrophages, Peritoneal - pathology | Male | NF-E2-Related Factor 2 - immunology | Leukocytes - immunology | Inflammation - complications | Liver - immunology | Female | NF-E2-Related Factor 2 - genetics | Shock, Hemorrhagic - pathology | Lung - pathology | Mice, Inbred C57BL | Macrophages, Peritoneal - immunology | Inflammation - immunology | Mice, Inbred ICR | Mice, Knockout | NF-E2-Related Factor 2 - analysis | Animals | Shock, Hemorrhagic - genetics | Inflammation - genetics | Mice | Mice, Inbred BALB C | Shock, Hemorrhagic - immunology | Macrophages, Peritoneal - metabolism | Lung - immunology
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11. Full Text Functional role of NRF2 in cervical carcinogenesis
by Ma, Jun-Qi and Tuersun, Hatila and Jiao, Shu-Juan and Zheng, Jian-He and Xiao, Jing-Bao and Hasim, Ayshamgul
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0133876
Nuclear factor erythroid-2-related factor 2 (NFE2L2) is a transcription factor associated with resistance to chemotherapy and increased tumor growth. NRF2 is... 
METHYLATION | CANCER CELLS | NF-E2-RELATED FACTOR-2 NRF2 | MULTIDISCIPLINARY SCIENCES | CELL-PROLIFERATION | TRANSCRIPTION FACTOR | EXPRESSION | ASSOCIATION | Cervical Intraepithelial Neoplasia - pathology | Cervix Uteri - metabolism | Cell Proliferation | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Carcinoma, Squamous Cell - pathology | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Uterine Cervical Neoplasms - pathology | Intracellular Signaling Peptides and Proteins - metabolism | Carcinogenesis - metabolism | DNA Methylation | Uterine Cervical Neoplasms - metabolism | Adult | Cervix Uteri - pathology | Female | NF-E2-Related Factor 2 - genetics | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Carcinogenesis - genetics | Intracellular Signaling Peptides and Proteins - analysis | Uterine Cervical Neoplasms - genetics | Carcinogenesis - pathology | NF-E2-Related Factor 2 - analysis | NF-E2-Related Factor 2 - metabolism | Cell Line, Tumor | CpG Islands | Cervical Intraepithelial Neoplasia - metabolism | Aged | Cervical Intraepithelial Neoplasia - genetics | Cell Movement | Epigenetic inheritance | Squamous cell carcinoma | Care and treatment | Chemotherapy | Development and progression | Research | Health aspects | Risk factors | Cancer | Oxidative stress | Transcription factors | Lung cancer | Metastasis | Drug resistance | Tissues | Carcinogenesis | Lymph nodes | Proteins | Carcinogens | Cell growth | Tumorigenesis | CpG islands | Aggressive behavior | Gynecology | Gene expression | Resistance factors | Pathology | Hospitals | Womens health | Cell lines | Cell migration | Cervical cancer | Tumors | Apoptosis
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12. Full Text Correlation of Nrf2, NQO1, MRP1, cmyc and p53 in colorectal cancer and their relationships to clinicopathologic features and survival
by Ji, Lili and Wei, Yingze and Jiang, Tao and Wang, Shuyang
International Journal of Clinical and Experimental Pathology, ISSN 1936-2625, 2014, Volume 7, Issue 3, pp. 1124 - 1131
Due to emergence of resistant tumor populations, prognosis for metastatic colorectal cancer (CRC) patients remains poor and five-year survival rate is still... 
Cmyc | NF-E2-related factor 2 (Nrf2) | NAD(P)H quinine oxidoreductase 1 (NQO1) | Colorectal cancer (CRC) | Multidrug resistant protein 1 (MRP1) | P53 | ACTIVATION | multidrug resistant protein 1 (MRP1) | HUMAN LUNG-CANCER | INDUCTION | PATHOLOGY | p53 | GENE | ONCOLOGY | PATHWAY | ANTIOXIDANT | NAD(P) H quinine oxidoreductase 1 (NQO1) | RESISTANCE | cmyc | TRANSCRIPTION FACTOR | ADAPTIVE RESPONSE | EXPRESSION | Colorectal Neoplasms - mortality | Immunohistochemistry | Multidrug Resistance-Associated Proteins - analysis | Prognosis | Tumor Suppressor Protein p53 - biosynthesis | Biomarkers, Tumor - analysis | Humans | Survival Rate | Multidrug Resistance-Associated Proteins - biosynthesis | Tumor Suppressor Protein p53 - analysis | NAD(P)H Dehydrogenase (Quinone) - biosynthesis | NF-E2-Related Factor 2 - analysis | NAD(P)H Dehydrogenase (Quinone) - analysis | NF-E2-Related Factor 2 - biosynthesis | Colorectal Neoplasms - metabolism
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13. Full Text A Generalizable Platform for Interrogating Target- and Signal-Specific Consequences of Electrophilic Modifications in Redox-Dependent Cell Signaling
by Lin, Hong-Yu and Haegele, Joseph A and Disare, Michael T and Lin, Qishan and Aye, Yimon
Journal of the American Chemical Society, ISSN 0002-7863, 1900, Volume 137, Issue 19, pp. 6232 - 6244
Despite the known propensity of small-molecule electrophiles to react with numerous cysteine-active proteins, biological actions of individual signal inducers... 
OXIDATIVE STRESS | ACTIVATION | LIPID-PEROXIDATION | NRF2 | POTENCY | ANTIOXIDANT | ENZYMES | NF-E2-RELATED FACTOR-2 | TRANSDUCTION | INDUCERS | CHEMISTRY, MULTIDISCIPLINARY | NF-E2-Related Factor 2 - analysis | Oxidation-Reduction | Signal Transduction | Humans | NF-E2-Related Factor 2 - metabolism | HEK293 Cells | Intracellular Signaling Peptides and Proteins - analysis | Models, Molecular | Intracellular Signaling Peptides and Proteins - metabolism | Kelch-Like ECH-Associated Protein 1 | Alkylation | Proteins | Oxidation-reduction reaction | Cellular signal transduction | Chemical properties | Research
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