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Free radical biology & medicine, ISSN 0891-5849, 2012, Volume 52, Issue 2, pp. 462 - 472
Journal Article
American journal of physiology. Heart and circulatory physiology, ISSN 1522-1539, 2010, Volume 299, Issue 1, pp. H18 - H24
.... Resveratrol was also shown to confer vasoprotection in animal models of type 2 diabetes and aging... 
Nuclear factor-E | Endothelial cell | Gracilis | related factor-2 | Resveratrol | MITOCHONDRIAL SUPEROXIDE-PRODUCTION | KAPPA-B ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | PHYSIOLOGY | VASCULAR OXIDATIVE STRESS | endothelial cell | NECROSIS-FACTOR-ALPHA | nuclear factor-E-2-related factor-2 | CORONARY-ARTERIES | NAD(P)H OXIDASE | gracilis | GENE-EXPRESSION | PERIPHERAL VASCULAR DISEASE | SMOOTH-MUSCLE-CELLS | TNF-ALPHA | resveratrol | SMALL-MOLECULE ACTIVATORS | Heme Oxygenase-1 - metabolism | Apoptosis - drug effects | Cardiovascular Diseases - prevention & control | Humans | Transcriptional Activation - drug effects | Male | Intracellular Signaling Peptides and Proteins - metabolism | Stilbenes - pharmacology | Cardiovascular Diseases - pathology | Coronary Vessels - metabolism | Dose-Response Relationship, Drug | Transfection | RNA Interference | NF-E2-Related Factor 2 - genetics | Glutathione Synthase - metabolism | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Genes, Reporter | Cytoprotection | Disease Models, Animal | Cardiovascular Diseases - etiology | Cardiovascular Diseases - physiopathology | Coronary Vessels - drug effects | Dietary Fats - adverse effects | Cardiovascular Diseases - metabolism | Endothelial Cells - metabolism | Cells, Cultured | Antioxidants - pharmacology | Femoral Artery - drug effects | NF-E2-Related Factor 2 - deficiency | Mice, Inbred ICR | Mice, Knockout | Response Elements - drug effects | Animals | NF-E2-Related Factor 2 - metabolism | Femoral Artery - metabolism | Glucose - metabolism | NAD(P)H Dehydrogenase (Quinone) - metabolism | Mice | Oxidative Stress - drug effects | Vasodilation - drug effects | Endothelial Cells - pathology | Endothelial Cells - drug effects | Physiological aspects | Care and treatment | Health aspects | Endothelium | nuclear factor-E2-related factor-2
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 07/2012, Volume 342, Issue 1, pp. 81 - 90
Nuclear factor erythroid 2-related factor 2 (Nrf2) is an antioxidant-activated transcription factor that recently emerged as a critical regulator of cellular defense against oxidative and inflammatory lesions. Resveratrol (Res... 
TRANSCRIPTION FACTOR NRF2 | CARCINOGENESIS | PROTECTION | PHENOLIC ANTIOXIDANTS | INDUCED LUNG INJURY | RATS | PHARMACOLOGY & PHARMACY | EXPRESSION | PULMONARY-FIBROSIS | MICE LACKING | MOLECULAR-MECHANISMS | Tumor Necrosis Factor-alpha - metabolism | NF-E2-Related Factor 2 - antagonists & inhibitors | Epithelial Cells - metabolism | Reactive Oxygen Species - metabolism | Apoptosis - drug effects | Antioxidants - metabolism | Epithelial Cells - drug effects | Humans | Transforming Growth Factor beta1 - metabolism | Tumor Necrosis Factor-alpha - genetics | Apoptosis - genetics | Stilbenes - pharmacology | Paraquat - antagonists & inhibitors | Myofibroblasts - metabolism | Inflammation - metabolism | Cell Death - genetics | Mitochondria - genetics | Inflammation - drug therapy | Cytoprotection - drug effects | NF-E2-Related Factor 2 - genetics | Response Elements - genetics | Cell Death - drug effects | Paraquat - pharmacology | Interleukin-6 - metabolism | Fibroblasts - metabolism | Interleukin-6 - genetics | Cells, Cultured | Oxidative Stress - genetics | Mitochondria - metabolism | Signal Transduction - genetics | Transforming Growth Factor beta1 - genetics | Mitochondria - drug effects | Myofibroblasts - drug effects | Mice, Knockout | Response Elements - drug effects | Animals | Signal Transduction - drug effects | Fibroblasts - drug effects | NF-E2-Related Factor 2 - metabolism | Cytoprotection - genetics | Mice | Oxidative Stress - drug effects | Index Medicus
Journal Article
Molecular cell, ISSN 1097-2765, 2013, Volume 51, Issue 2, pp. 236 - 248
.... The underlying mechanisms by which FH loss increases ROS and HIF-1 are not fully understood. Here, we report that glutamine-dependent oxidative citric acid cycle metabolism is required to generate fumarate and increase ROS and HIF-1 levels... 
ACTIVATION | METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | HYDRATASE | CHEMICAL-MODIFICATION | MUTATIONS | HYPOXIA | CANCER | RENAL-CELL CARCINOMA | CELL BIOLOGY | Antioxidants | Enzymes | Medical colleges | Thiols | Metabolites | Histones | Citric acid | Glutamine
Journal Article
Nature (London), ISSN 1476-4687, 2011, Volume 475, Issue 7354, pp. 106 - 109
... that responds to cellular stressors and is predominantly regulated by the transcription factor Nrf2... 
TRANSFORMATION | OXIDATIVE STRESS | ACTIVATION | INHIBITION | K-RAS | PATHWAY | MULTIDISCIPLINARY SCIENCES | PANCREATIC-CANCER | HEME OXYGENASE-1 | MUTATIONS | EXPRESSION | NIH 3T3 Cells | Cell Proliferation | Pancreatic Neoplasms - metabolism | Reactive Oxygen Species - metabolism | Cytoskeletal Proteins - genetics | Proto-Oncogene Proteins p21(ras) - genetics | Antioxidants - metabolism | Humans | JNK Mitogen-Activated Protein Kinases - metabolism | Intracellular Signaling Peptides and Proteins - metabolism | Extracellular Signal-Regulated MAP Kinases - metabolism | MAP Kinase Signaling System | Mitogen-Activated Protein Kinase Kinases - metabolism | Cell Transformation, Neoplastic - genetics | Cytoskeletal Proteins - metabolism | NF-E2-Related Factor 2 - genetics | Intracellular Signaling Peptides and Proteins - genetics | Kelch-Like ECH-Associated Protein 1 | Proto-Oncogene Proteins B-raf - metabolism | Fibroblasts - metabolism | Proto-Oncogene Proteins p21(ras) - metabolism | Oncogenes - genetics | Oxidation-Reduction | Pancreatic Neoplasms - pathology | Cells, Cultured | Pancreatic Neoplasms - genetics | NF-E2-Related Factor 2 - deficiency | Cell Transformation, Neoplastic - metabolism | Animals | Proto-Oncogene Proteins B-raf - genetics | Genes, myc - genetics | NF-E2-Related Factor 2 - metabolism | Adaptor Proteins, Signal Transducing - genetics | Alleles | Cell Line, Tumor | Mice | Adaptor Proteins, Signal Transducing - metabolism | Cell Transformation, Neoplastic - pathology | Polymerase chain reaction | Usage | Reactive oxygen species | Physiological aspects | Research | Gene expression | Oncogenes | Studies | Mass spectrometry | Rodents | Evacuations & rescues | Cancer
Journal Article
Hypertension (Dallas, Tex. 1979), ISSN 1524-4563, 2015, Volume 66, Issue 6, pp. 1240 - 1250
Journal Article
Nature genetics, ISSN 1546-1718, 2015, Volume 47, Issue 12, pp. 1475 - 1481
.... Here we show that the activity of this pathway is highly heterogeneous and is regulated by NRF2, a transcription factor frequently deregulated in NSCLC... 
ACTIVATION | PROTEIN | GLUTAMINE | PATHWAY | GLUCOSE | GROWTH | GENETICS & HEREDITY | GENE-EXPRESSION | IMPAIR | CARCINOMA | KEAP1 MUTATIONS | RNA, Small Interfering - genetics | NF-E2-Related Factor 2 - antagonists & inhibitors | Cell Proliferation | Lung Neoplasms - mortality | Humans | Lung Neoplasms - metabolism | Gene Expression Regulation, Neoplastic | Lung Neoplasms - pathology | Serine - biosynthesis | Immunoenzyme Techniques | Adenocarcinoma - metabolism | Carcinoma, Non-Small-Cell Lung - secondary | Biomarkers, Tumor - metabolism | NF-E2-Related Factor 2 - genetics | Adenocarcinoma - genetics | Tumor Cells, Cultured | Real-Time Polymerase Chain Reaction | Lung Neoplasms - genetics | Carcinoma, Non-Small-Cell Lung - genetics | RNA, Messenger - genetics | Carcinoma, Non-Small-Cell Lung - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Carcinoma, Non-Small-Cell Lung - mortality | Adenocarcinoma - secondary | Blotting, Western | Xenograft Model Antitumor Assays | Animals | NF-E2-Related Factor 2 - metabolism | Biomarkers, Tumor - genetics | Mice | Adenocarcinoma - mortality | Apoptosis | Transcription factors | Cell metabolism | Development and progression | Genetic aspects | Genetic transcription | Lung cancer, Non-small cell | Properties | Health aspects | Medical research | Enzymes | Lung cancer | Biosynthesis | RNA polymerase | Metabolism | Gene expression | Experiments | Metabolites | Scientific imaging | Tumorigenesis | Labeling | Bioinformatics | Mass spectrometry
Journal Article
Antioxidants & redox signaling, ISSN 1523-0864, 01/2013, Volume 18, Issue 1, pp. 66 - 79
Journal Article
The Journal of biological chemistry, ISSN 1083-351X, 2014, Volume 289, Issue 22, pp. 15244 - 15258
Journal Article
Journal Article