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Molecular Cell, ISSN 1097-2765, 10/2016, Volume 64, Issue 2, pp. 251 - 266
Polyubiquitin chains of different topologies regulate diverse cellular processes. K48- and K63-linked chains, the two most abundant chain types, regulate... 
NF-κB | CYLD | AQUA | proteomics | Lys63 | inflammation | TRAF6 | HUWE1 | Lys48 | ACTIVATION | COMPLEX | INHIBITION | SPECIFICITY | ELONGATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CYLD USP | DEGRADATION | POLYUBIQUITIN CHAIN | MECHANISMS | LIGASE | CELL BIOLOGY | Adaptor Proteins, Signal Transducing - chemistry | Interleukin-1beta - pharmacology | Deubiquitinating Enzyme CYLD | Humans | Ubiquitin - metabolism | Substrate Specificity | NF-kappa B - metabolism | NF-kappa B - chemistry | Polyubiquitin - genetics | Ubiquitination | Tumor Suppressor Proteins - chemistry | Tumor Suppressor Proteins - genetics | Lysine - metabolism | Protein Interaction Domains and Motifs | Osteoblasts - cytology | TNF Receptor-Associated Factor 6 - genetics | Binding Sites | Polyubiquitin - chemistry | Polyubiquitin - metabolism | Recombinant Proteins - metabolism | Amino Acid Sequence | Protein Conformation, alpha-Helical | Gene Expression | Tumor Suppressor Proteins - metabolism | Signal Transduction | Osteoblasts - drug effects | Ubiquitin - chemistry | Ubiquitin-Protein Ligases - metabolism | Models, Molecular | Recombinant Proteins - chemistry | Recombinant Proteins - genetics | Ubiquitin - genetics | Ubiquitin-Protein Ligases - chemistry | Sequence Alignment | NF-kappa B - genetics | Protein Conformation, beta-Strand | Adaptor Proteins, Signal Transducing - genetics | TNF Receptor-Associated Factor 6 - chemistry | TNF Receptor-Associated Factor 6 - metabolism | Cell Line, Tumor | Protein Binding | Adaptor Proteins, Signal Transducing - metabolism | Lysine - chemistry | Osteoblasts - metabolism | Ubiquitin-Protein Ligases - genetics | Index Medicus
Journal Article
Seminars in Immunology, ISSN 1044-5323, 2006, Volume 18, Issue 5, pp. 263 - 275
BAFF, APRIL and their receptors play important immunological roles, especially in the B cell arm of the immune system. A number of splice isoforms have been... 
Signaling | BAFF | B cells | Structure | Splice variants | MATURATION ANTIGEN | signaling | PROTEIN-KINASE | splice variants | COMMON VARIABLE IMMUNODEFICIENCY | LYMPHOCYTE STIMULATOR | T-CELL | IMMUNOLOGY | structure | TNF FAMILY | CELL-ACTIVATING FACTOR | NECROSIS-FACTOR FAMILY | NF-KAPPA-B | AUTOIMMUNE-DISEASE | B-Cell Activating Factor - physiology | Alternative Splicing | Humans | Substrate Specificity | Structure-Activity Relationship | Lymphocyte Subsets - immunology | Immunoglobulin Class Switching - physiology | Protein Kinase C-delta - antagonists & inhibitors | B-Cell Activating Factor - immunology | Tumor Necrosis Factor Ligand Superfamily Member 13 - chemistry | B-Cell Activation Factor Receptor - genetics | B-Cell Activation Factor Receptor - immunology | B-Cell Activation Factor Receptor - chemistry | Tumor Necrosis Factor Ligand Superfamily Member 13 - immunology | B-Lymphocytes - cytology | Transmembrane Activator and CAML Interactor Protein - chemistry | Signal Transduction | B-Cell Maturation Antigen - physiology | Lymphocyte Activation | B-Cell Activating Factor - chemistry | Tumor Necrosis Factor Ligand Superfamily Member 13 - physiology | Models, Molecular | B-Cell Activation Factor Receptor - physiology | Transmembrane Activator and CAML Interactor Protein - physiology | Protein Interaction Mapping | Transmembrane Activator and CAML Interactor Protein - genetics | Animals | B-Lymphocytes - immunology | B-Cell Activating Factor - genetics | NF-kappa B - physiology | Protein Conformation | Tumor Necrosis Factor Ligand Superfamily Member 13 - genetics | Mice | NF-kappa B p50 Subunit - physiology | Apoptosis - physiology | Transmembrane Activator and CAML Interactor Protein - immunology | Antigen Presentation - physiology
Journal Article
Journal Article
Nature Reviews Cancer, ISSN 1474-175X, 02/2012, Volume 12, Issue 2, pp. 121 - 132
It is only recently that the full importance of nuclear factor-kappa B (NF-kappa B) signalling to cancer development has been understood. Although much... 
CROSS-TALK | TARGET GENE-EXPRESSION | ONCOLOGY | DEPENDENT TRANSCRIPTION | MOUSE MODEL | PUTATIVE TUMOR-SUPPRESSOR | DOWN-REGULATION | POSTTRANSLATIONAL MODIFICATIONS | CELL-GROWTH | MICE LACKING | NEGATIVE REGULATOR | NF-kappa B - chemistry | Neoplasms - physiopathology | Genes, Tumor Suppressor | Humans | NF-kappa B - physiology
Journal Article
JOURNAL OF PHYSICAL CHEMISTRY B, ISSN 1520-6106, 04/2019, Volume 123, Issue 13, pp. 2882 - 2888
The globular transcriptional adapter zinc binding 1 (TAZ1) domain of CREB binding protein participates in protein-protein interactions that are involved in... 
INTRINSICALLY DISORDERED PROTEINS | DOMAIN | NMR RELAXATION | ORDER PARAMETERS | DYNAMICS | CHEMISTRY, PHYSICAL | ROTATIONAL DIFFUSION ANISOTROPY | NF-KAPPA-B | BINDING | MODEL-FREE | INSIGHTS | Biological Sciences | Naturvetenskap | Natural Sciences | Kemi | Biologiska vetenskaper | Chemical Sciences
Journal Article
Journal Article