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Nature Communications, ISSN 2041-1723, 06/2014, Volume 5, Issue 1, pp. 4172 - 4172
Journal Article
Journal Article
Molecular Cell, ISSN 1097-2765, 10/2014, Volume 56, Issue 2, pp. 219 - 231
Proinflammatory stimuli elicit rapid transcriptional responses via transduced signals to master regulatory transcription factors. To explore the role of... 
RNA-POLYMERASE-II | SELECTIVE-INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL IDENTITY | DISEASE | GENE-EXPRESSION | ATHEROSCLEROSIS | BROMODOMAIN PROTEIN BRD4 | TRANSCRIPTIONAL ELONGATION | P-TEFB | BET BROMODOMAINS | CELL BIOLOGY | Endothelium, Vascular - cytology | Transcription, Genetic - drug effects | Endothelial Cells | Atherosclerosis - genetics | Humans | Regulatory Sequences, Nucleic Acid | NF-kappa B p50 Subunit - genetics | Transcription Factor RelA - genetics | Cell Movement - genetics | Cell Movement - immunology | NF-kappa B p50 Subunit - immunology | E-Selectin - biosynthesis | Transcription Factor RelA - immunology | Acetylation | Transcription Initiation, Genetic | Transcription Factors - immunology | Macrophages - immunology | Endothelium, Vascular - immunology | Atherosclerosis - immunology | Signal Transduction | Mice, Inbred C57BL | Cells, Cultured | Transcription Factors - antagonists & inhibitors | Inflammation - immunology | Nuclear Proteins - immunology | Mice, Knockout | Azepines - pharmacology | Cell Adhesion - immunology | Triazoles - pharmacology | Tumor Necrosis Factor-alpha - pharmacology | Animals | Enhancer Elements, Genetic | Nuclear Proteins - antagonists & inhibitors | Inflammation - genetics | Protein Binding | RNA Polymerase II - genetics | Vascular Cell Adhesion Molecule-1 - biosynthesis | Mice | Histones - metabolism | SOXF Transcription Factors - genetics | Chromatin - genetics | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 10/2014, Volume 41, Issue 4, pp. 567 - 578
Programmed necrosis or necroptosis is an inflammatory form of cell death that critically requires the receptor-interacting protein kinase 3 (RIPK3). Here we... 
PROTECTS MICE | APOPTOSIS | ACTIVATION | NECROSIS | INFLAMMATION | IN-VIVO | KINASE | INDUCED COLITIS | RECEPTOR | IMMUNOLOGY | INTESTINAL EPITHELIAL-CELLS | Dextran Sulfate | Receptors, Interleukin - biosynthesis | Colitis - genetics | Dendritic Cells - immunology | Transcription Factor RelB - immunology | Caspase 1 - metabolism | Adoptive Transfer | NF-kappa B p50 Subunit - genetics | Enzyme Activation - immunology | Lipopolysaccharides | Necrosis - immunology | NF-kappa B p50 Subunit - immunology | RNA, Messenger - biosynthesis | Signal Transduction - immunology | Bone Marrow Cells - immunology | Interleukins - immunology | Female | Interleukin-1beta - biosynthesis | Interleukins - biosynthesis | Wound Healing - genetics | Colitis - immunology | Macrophages - immunology | Transcription Factor RelB - genetics | Gene Expression Regulation - immunology | Mice, Inbred C57BL | Interleukin-1beta - immunology | Inflammation - immunology | Interleukin-23 - immunology | Mice, Knockout | Receptor-Interacting Protein Serine-Threonine Kinases - genetics | Animals | Apoptosis - immunology | Interleukin-23 - biosynthesis | Mice | Enzyme Activation - genetics | Dendritic Cells - transplantation | Dextran | Cytokines | Dendritic cells | Sulfates | Inflammatory bowel disease | Rodents | Life sciences | Histology | Kinases | Experiments | Apoptosis | Index Medicus
Journal Article
Nature Immunology, ISSN 1529-2908, 01/2014, Volume 15, Issue 1, pp. 54 - 62
miR-126 is a microRNA expressed predominately by endothelial cells and controls angiogenesis. We found miR-126 was required for the innate response to... 
PLASMACYTOID DENDRITIC CELLS | SYSTEMIC-LUPUS-ERYTHEMATOSUS | ACTIVATION | VASCULAR INTEGRITY | MICRORNA MIR-126 | PREDENDRITIC CELLS | RECEPTOR | INDUCTION | IMMUNOLOGY | EXPRESSION | I INTERFERON | Oligonucleotide Array Sequence Analysis | Dendritic Cells - immunology | Humans | Immunity, Innate - genetics | Toll-Like Receptor 9 - genetics | Immunoblotting | MicroRNAs - metabolism | Transcriptome - immunology | NF-kappa B p50 Subunit - genetics | Vascular Endothelial Growth Factor Receptor-2 - immunology | Vascular Endothelial Growth Factor Receptor-2 - genetics | NF-kappa B p50 Subunit - immunology | Toll-Like Receptor 9 - immunology | HIV Infections - immunology | Flow Cytometry | Oligodeoxyribonucleotides - genetics | Toll-Like Receptor 7 - immunology | Dendritic Cells - metabolism | Toll-Like Receptor 7 - genetics | Interferon-alpha - metabolism | Oligodeoxyribonucleotides - immunology | Toll-Like Receptor 7 - metabolism | NF-kappa B p50 Subunit - metabolism | HIV Infections - virology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Mice, Transgenic | Nucleic Acids - metabolism | MicroRNAs - immunology | Reverse Transcriptase Polymerase Chain Reaction | Interferon-alpha - immunology | Mice, Knockout | Immunity, Innate - immunology | Animals | Interferon-alpha - blood | Mice | MicroRNAs - genetics | Nucleic Acids - immunology | Toll-Like Receptor 9 - metabolism | Host-parasite relationships | Physiological research | MicroRNA | Immune response | Research | Identification and classification | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2012, Volume 7, Issue 9, pp. e45279 - e45279
Dendritic cells play a central role in keeping the balance between immunity and immune tolerance. A key factor in this equilibrium is the lifespan of DC, as... 
IMMUNOTHERAPY | MACROPHAGES | MULTIDISCIPLINARY SCIENCES | IN-VIVO | PERIPHERAL TOLERANCE | ANTIGEN PRESENTATION | STEADY-STATE | T-CELL | MATURATION | RECEPTORS | EXPRESSION | Forkhead Transcription Factors - immunology | Interleukin-1 - genetics | Interleukin-18 - immunology | Interferon-beta - immunology | Gene Expression - drug effects | Dendritic Cells - immunology | Half-Life | NF-kappa B p50 Subunit - genetics | CD4-Positive T-Lymphocytes - immunology | NF-kappa B p50 Subunit - immunology | Melanoma - genetics | Interleukin-1 - immunology | Interferon-beta - genetics | Dendritic Cells - drug effects | Immune Tolerance - drug effects | Skin Neoplasms - pathology | Skin Neoplasms - immunology | Melanoma - pathology | Forkhead Transcription Factors - genetics | Cell Differentiation - immunology | Adaptive Immunity - drug effects | Animals | Cell Differentiation - drug effects | Melanoma - immunology | CD8-Positive T-Lymphocytes - drug effects | Skin Neoplasms - genetics | Lipopolysaccharides - pharmacology | Antigen Presentation - drug effects | Cell Proliferation - drug effects | Mice | CD8-Positive T-Lymphocytes - immunology | Dendritic Cells - transplantation | Interleukin-18 - genetics | CD4-Positive T-Lymphocytes - drug effects | CD8 antigen | Vaccination | Activation | Lymphocytes T | Immunity | Lipopolysaccharides | Cell activation | Lymphocytes | Immunotherapy | Rodents | Interleukin 1 | Foxp3 protein | NF-κB protein | Antigens | Immune response | Cytokines | Maturation | Dendritic cells | Immunoregulation | Melanoma | Inflammation | T cell receptors | Adaptive immunity | Immunological tolerance | Interleukin 18 | CD4 antigen | Life span | Interferon | Laboratory animals | Cancer | Apoptosis | Index Medicus
Journal Article
Journal Article
Science Signaling, ISSN 1945-0877, 06/2009, Volume 2, Issue 75, pp. ra28 - ra28
The activation of macrophages through Toll-like receptor (TLR) pathways leads to the production of a broad array of cytokines and mediators that coordinate the... 
PROTEIN-KINASE-A | RNA INTERFERENCE | CYCLIC-AMP | VASOACTIVE-INTESTINAL-PEPTIDE | NECROSIS-FACTOR-ALPHA | NF-KAPPA-B | SIGNALING COMPLEXES | ANCHORING PROTEIN | MONOCYTIC CELLS | INNATE IMMUNITY | CELL BIOLOGY | Tumor Necrosis Factor-alpha - genetics | NF-kappa B p50 Subunit - genetics | Dinoprostone - immunology | NF-kappa B p50 Subunit - immunology | A Kinase Anchor Proteins - genetics | Inflammation - metabolism | Cyclic AMP-Dependent Protein Kinases - genetics | RNA Interference | Tumor Necrosis Factor-alpha - immunology | Cyclic AMP - genetics | Phosphorylation - immunology | Phosphorylation - drug effects | Cyclic AMP - metabolism | A Kinase Anchor Proteins - metabolism | Macrophages - immunology | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Line | Second Messenger Systems - drug effects | NF-kappa B p50 Subunit - metabolism | Dinoprostone - genetics | Gene Expression Regulation - immunology | Toll-Like Receptor 4 - genetics | Inflammation - immunology | Toll-Like Receptor 4 - immunology | Second Messenger Systems - immunology | Toll-Like Receptor 4 - metabolism | Dinoprostone - metabolism | Gene Expression Regulation - drug effects | Macrophages - metabolism | Animals | A Kinase Anchor Proteins - immunology | Cyclic AMP-Dependent Protein Kinases - immunology | Cyclic AMP - immunology | Lipopolysaccharides - pharmacology | Inflammation - genetics | Mice | Tumor Necrosis Factor-alpha - biosynthesis | Index Medicus
Journal Article
Oncogene, ISSN 0950-9232, 07/2017, Volume 36, Issue 29, pp. 4224 - 4232
Journal Article
Journal Article
Journal of Experimental Medicine, ISSN 0022-1007, 2016, Volume 213, Issue 4, pp. 621 - 641
Journal Article