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Journal Article
Nature (London), ISSN 1476-4687, 2019, Volume 568, Issue 7752, pp. 351 - 356
.... Here we report that concomitant metabolic and hypertensive stress in mice-elicited by a combination of high-fat diet and inhibition of constitutive nitric oxide synthase using N-omega-nitro-larginine methyl ester (L-NAME... 
S-NITROSYLATION | INHIBITION | DYSFUNCTION | MODEL | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | Humans | Heart Failure - physiopathology | Diet, High-Fat - adverse effects | Male | Heart Failure - prevention & control | Myocytes, Cardiac - enzymology | Nitric Oxide Synthase Type II - antagonists & inhibitors | Protein-Serine-Threonine Kinases - metabolism | Disease Models, Animal | NG-Nitroarginine Methyl Ester - pharmacology | Endoribonucleases - metabolism | Signal Transduction | Mice, Inbred C57BL | Nitric Oxide Synthase Type II - deficiency | Heart Failure - metabolism | Nitrosative Stress | Stroke Volume | Myocytes, Cardiac - pathology | Phenotype | Animals | Nitric Oxide Synthase Type II - genetics | X-Box Binding Protein 1 - metabolism | Myocytes, Cardiac - metabolism | Mice | X-Box Binding Protein 1 - genetics | Nitric Oxide Synthase Type II - metabolism | Heart failure | Care and treatment | Diagnosis | Health aspects | Nitric oxide | Heart | Genetic suppression | Kinases | High fat diet | Proteins | Arginine | Protein folding | Heart diseases | Hypertension | Obesity | Phenotypes | Inositol | Splicing | Cardiomyocytes | Pharmacology | Inflammation | Metabolism | Morbidity | Nitric-oxide synthase | NG-Nitroarginine methyl ester | Musculoskeletal system | Diet | Myocardium | Endonuclease | Ejection fraction
Journal Article
Biological & pharmaceutical bulletin, ISSN 0918-6158, 2018, Volume 41, Issue 9, pp. 1406 - 1413
...) rats were pretreated with SFI and NG-nitro-L-arginine methyl ester (L-NAME) via tail vein injection and then rats were subjected to ischemia by occlusion of the left anterior descending coronary artery for 30... 
nitric oxide | ischemia reperfusion injury | NG-nitro-L-arginine methyl ester (L-NAME) | left ventricular function | Shenfu injection | nitro-L-arginine methyl ester (L-NAME) | Ischemia reperfusion injury | Nitric oxide | Left ventricular function | ISCHEMIA/REPERFUSION INJURY | OXIDATIVE STRESS | DONOR | PHOSPHORYLATION | NITRIC-OXIDE SYNTHASE | MITOCHONDRIA | N-G-nitro-L-arginine methyl ester (L-NAME) | DISEASE | PHARMACOLOGY & PHARMACY | MICE | CONTRACTILE FUNCTION | CARDIOPROTECTION | Drugs, Chinese Herbal - pharmacology | Rats | Male | Treatment Outcome | Cardiotonic Agents - pharmacology | Enzyme Activation - drug effects | Rats, Sprague-Dawley | Myocardial Reperfusion Injury - enzymology | Cardiotonic Agents - therapeutic use | Myocardial Reperfusion Injury - diagnostic imaging | Animals | Nitric Oxide Synthase Type III - metabolism | Drugs, Chinese Herbal - therapeutic use | Enzyme Activation - physiology | Myocardial Reperfusion Injury - prevention & control | Heart | Occlusion | Myocardial infarction | Systolic pressure | Phosphorylation | Diastolic pressure | Creatine kinase | Myocardial ischemia | AKT protein | Creatine | Kinases | Western blotting | Reperfusion | Ischemia | Arginine | Rodents | Calcium-binding protein | Blood pressure | Cerebral infarction | Echocardiography | Level (quantity) | Coronary artery | Lactate dehydrogenase | Injection | L-Lactate dehydrogenase | Nitric-oxide synthase | Stroke volume | NG-Nitroarginine methyl ester | Troponin | Lactic acid | Hemodynamics | Ventricle
Journal Article
Hypertension (Dallas, Tex. 1979), ISSN 0194-911X, 02/2012, Volume 59, Issue 2 Suppl 1, pp. 485 - 492
Journal Article
PloS one, ISSN 1932-6203, 07/2015, Volume 10, Issue 7, p. e0132367
Histamine is a mediator of allergic inflammation released mainly from mast cells. Although histamine strongly increases vascular permeability, its precise... 
ADHESION | LEAKAGE | THROMBIN | INFLAMMATION | MULTIDISCIPLINARY SCIENCES | JUNCTIONS | NITRIC-OXIDE | VE-CADHERIN | ADHERENS | BRADYKININ | MICROVASCULAR PERMEABILITY | Blood Vessels - metabolism | Ear, External - pathology | Humans | Capillary Permeability - drug effects | Nitric Oxide Synthase - antagonists & inhibitors | Endothelium, Vascular - drug effects | Male | Histamine - metabolism | Receptors, Histamine H1 - metabolism | Phenylephrine - pharmacology | rho-Associated Kinases - metabolism | Protein Kinase C - metabolism | Female | NG-Nitroarginine Methyl Ester - pharmacology | Vasoconstrictor Agents - pharmacology | Histamine - pharmacology | Endothelial Cells - metabolism | Cells, Cultured | Enzyme Inhibitors - pharmacology | Animals | Endothelium, Vascular - metabolism | Ear, External - drug effects | Blood Vessels - drug effects | Ear, External - blood supply | Mice | Nitric Oxide Synthase - metabolism | Pyridines - pharmacology | Histamine Agonists - pharmacology | Vasodilation - drug effects | Blood Vessels - physiology | Microscopy, Fluorescence | Blood Flow Velocity - drug effects | Endothelial Cells - drug effects | Histamine | Nitric oxide | Hostages | Inflammation | Permeability | Blood flow | Endothelium | Regulators | Protein kinase C | Smooth muscle | Kinases | Blood | Proteins | Anaphylaxis | Phenylephrine | Physiology | Life sciences | Inhibition | Localization | Vascular endothelial growth factor | Hypersensitivity | Vasoconstriction | Pharmacology | Cadherin | Nitric-oxide synthase | Endothelial cells | Flow | NG-Nitroarginine methyl ester | Studies | Degranulation | Skin | Mast cells | Microvasculature | Disruption | Veins & arteries
Journal Article
Journal Article
American Journal of Pathology, The, ISSN 0002-9440, 2008, Volume 172, Issue 3, pp. 830 - 838
Journal Article
Free radical biology & medicine, ISSN 0891-5849, 08/2014, Volume 73, pp. 51 - 59
Microglia are the resident immune cells in the brain. Microglial activation is characteristic of several inflammatory and neurodegenerative diseases including... 
Peroxynitrite | Free radicals | Protein radical | Inducible nitric oxide synthase | Lipopolysaccharide | Nitrone adducts | Parkinson disease | Microglia | NADPH OXIDASE | OXIDATIVE STRESS | MACROPHAGES | BIOCHEMISTRY & MOLECULAR BIOLOGY | INOS EXPRESSION | KAPPA-B | LIPOPOLYSACCHARIDE-ACTIVATED MICROGLIA | REACTIVE OXYGEN | ENDOCRINOLOGY & METABOLISM | GENERATION | TYROSINE NITRATION | PARKINSONS-DISEASE | Microglia - metabolism | Metalloporphyrins - pharmacology | Lipopolysaccharides | Thiocarbamates - pharmacology | RNA Interference | Nitric Oxide Synthase Type II - antagonists & inhibitors | Spin Trapping | Acetophenones - pharmacology | Free Radicals - metabolism | Proline - pharmacology | Microglia - cytology | NG-Nitroarginine Methyl Ester - pharmacology | NF-kappa B - antagonists & inhibitors | Proline - analogs & derivatives | Enzyme Inhibitors - pharmacology | Imidazoles - pharmacology | Antioxidants - pharmacology | Neurodegenerative Diseases - metabolism | Coumarins - pharmacology | Animals | Nitric Oxide Synthase Type II - genetics | p38 Mitogen-Activated Protein Kinases - antagonists & inhibitors | Peroxynitrous Acid - metabolism | Amidines - pharmacology | Mice | Pyridines - pharmacology | RNA, Small Interfering | Benzylamines - pharmacology | Cell Line, Transformed | Boronic Acids - pharmacology | Nitric Oxide Synthase Type II - metabolism | Nitration | Nervous system diseases | Multiple sclerosis | Analysis | Nitric oxide | Environmental health | Physiological aspects | Alzheimer's disease | Index Medicus | Inducible nitric | oxide synthase | LPS | Parkinson’s disease
Journal Article