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AMERICAN JOURNAL OF PATHOLOGY, ISSN 0002-9440, 03/2019, Volume 189, Issue 3, pp. 482 - 491
The transcription factor Nur77 belongs to the NR4A subfamily of nuclear hormone receptors. It features an atypical ligand-binding site that precludes canonical... 
NGFI-B | ACTIVATION | GENE | AKT PHOSPHORYLATES | PATHOLOGY | NF-KAPPA-B | STEROID-RECEPTOR | CELL | ORPHAN NUCLEAR RECEPTOR | NUR77 EXPRESSION | TERMINAL KINASE
Journal Article
JOURNAL OF BIOLOGICAL CHEMISTRY, ISSN 0021-9258, 03/2019, Volume 294, Issue 13, pp. 4889 - 4897
The Nr4a subfamily of nuclear receptor comprises three members in mammalian cells: Nur77/Nr4a1, Nurr1/Nr4a2, and Nor1/Nr4a3. Nr4a proteins play key roles in... 
cytokine | PATHWAYS | ACTIVATION | insulin | NOR-1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | KINASE | apoptosis | PATHOGENESIS | SKELETAL-MUSCLE | NGFI-B | Nr4a | METABOLISM | beta-cell | pancreas | NUR77 | nuclear receptor | diabetes | EXPRESSION
Journal Article
FASEB journal : official publication of the Federation of American Societies for Experimental Biology, ISSN 0892-6638, 06/2019, Volume 33, Issue 6, pp. 6736 - 6747
Glycerol kinase (Gyk), consisting of 4 isoforms, plays a critical role in metabolism by converting glycerol to glycerol 3-phosphate in an ATP-dependent... 
protein–protein interaction | glucose homeostasis | diabetes | gluconeogenesis | DOMAIN | LIPID-METABOLISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | STIMULATED FACTOR | DEFICIENCY | CELL BIOLOGY | NGFI-B | GENE | BIOLOGY | NURR1 | protein-protein interaction | BINDING | EXPRESSION | MEDIATES TRANSACTIVATION
Journal Article
AGING CELL, ISSN 1474-9726, 02/2019, Volume 18, Issue 1, p. e12866
The orphan nuclear receptor Nurr1 (also known as NR4A2) is critical for the development and maintenance of midbrain dopaminergic neurons, and is associated... 
AMYLOID DEPOSITION | NUCLEAR RECEPTORS | Nurr1 | NEURODEGENERATION | agonist | amyloid plaques | BETA | CELL BIOLOGY | GERIATRICS & GERONTOLOGY | NGFI-B | NEURONS | 5XFAD mouse | ANIMAL-MODEL | MICE | DEFICITS | Alzheimer's disease | EXPRESSION | Brain | Neurons | Analysis | Target marketing
Journal Article
Kidney International, ISSN 0085-2538, 12/2014, Volume 86, Issue 6, pp. 1106 - 1115
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 04/2005, Volume 280, Issue 17, pp. 16942 - 16948
Insulin-like growth factor-binding protein-3 (IGFBP-3) induces apoptosis by its ability to bind insulin-like growth factors (IGFs) as well as its... 
BREAST-CANCER CELLS | LUNG-CANCER | NGFI-B | TRANSCRIPTIONAL ACTIVATION | RETINOIC ACID | FACTOR-BINDING PROTEIN-3 | SIGNALING PATHWAY | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROSTATE-CANCER | NUCLEAR EXPORT | ORPHAN RECEPTOR TR3
Journal Article
The Journal of neuroscience : the official journal of the Society for Neuroscience, ISSN 0270-6474, 06/2019, Volume 39, Issue 25, pp. 4999 - 5009
Journal Article
Microvascular Research, ISSN 0026-2862, 03/2019, Volume 122, pp. 22 - 33
Pathological angiogenesis is a hallmark of many diseases. Previously, we reported that orphan nuclear receptor TR3/Nur77 (human homolog, Nur77, mouse homolog)... 
Promoter | Angiogenesis | TR3/Nur77 | Integrin | Proliferation | Migration | CELLS | PROTEIN | PERMEABILITY | ANTIANGIOGENIC THERAPY | NGFI-B | TUMOR REFRACTORINESS | RESISTANCE | NUR77 | NURR1 | PERIPHERAL VASCULAR DISEASE | ANTI-VEGF THERAPY | Growth factors | Analysis | Integrins
Journal Article
Stem Cells and Development, ISSN 1547-3287, 07/2018, Volume 27, Issue 14, pp. 968 - 975
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease. The incidence of PD cases increases with age,... 
Comprehensive Reviews | development | induced pluripotent stem cells | Parkinson's disease | organoids | MEDICINE, RESEARCH & EXPERIMENTAL | MOUSE | RECEPTOR NURR1 | MICROGLIA-LIKE CELLS | SUBSTANTIA-NIGRA | LRRK2 MUTATION | CELL & TISSUE ENGINEERING | TRANSPLANTATION | PLURIPOTENT STEM-CELLS | DOPAMINE NEURONS | NGFI-B | GENE | HEMATOLOGY | EXPRESSION
Journal Article
Journal Article