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Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 39, pp. 65730 - 65742
It has been recognized that Na+/H+ Exchanger Regulatory Factor 1 (NHERF1) in breast cancer (BC) acts as a tumor suppressor or as an oncogenic protein,... 
Immunohistochemistry | exchanger regulatory factor 1 (NHERF1) | Breast cancer | BRCA1 | PARP1 | CELLS | PHOSPHOPROTEIN-50 | DNA-DAMAGE RESPONSE | Na plus /H plus exchanger regulatory factor 1 (NHERF1) | PTEN | breast cancer | CELL BIOLOGY | NUCLEAR NHERF1 | OVEREXPRESSION | REPAIR | COLORECTAL-CANCER | PROTEIN EXPRESSION | immunohistochemistry | PROGNOSTIC-SIGNIFICANCE
Journal Article
CANCERS, ISSN 2072-6694, 06/2019, Volume 11, Issue 7, p. 1035
The Wnt pathway is involved in the progression of breast cancer (BC). We aimed to evaluate the expression of some components of the Wnt pathway (beta-catenin,... 
NHERF1 EXPRESSION | ACTIVATION | NHERF1 | Wnt pathway | MARKER | BETA-CATENIN | Breast Cancer | FAMILY | NUCLEAR NHERF1 | OVEREXPRESSION | RECEPTOR 2 | ONCOLOGY | COLORECTAL-CANCER | TCF1
Journal Article
Journal of Cellular and Molecular Medicine, ISSN 1582-1838, 08/2013, Volume 17, Issue 8, pp. 1025 - 1037
Journal Article
Oncotarget, ISSN 1949-2553, 06/2018, Volume 9, Issue 47, pp. 28652 - 28665
Meningioma is a primary brain tumor arising from the neoplastic transformation of meningothelial cells. Several histological variants of meningioma have been... 
Epithelial differentiation | NF2 | NHERF1/EBP50 | Chordoid meningioma | Microvilli
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 01/2019, Volume 294, Issue 3, pp. 887 - 901
Unlike other ErbB family members, HER2 levels are maintained on the cell surface when the receptor is activated, allowing prolonged signaling and contributing... 
heat shock protein 90 (Hsp90) | NHERF1 | protein kinase C (PKC) | scaffold protein | breast cancer | ErbB2/HER2 | ezrin | PDZ domain | PMCA2 | LOCALIZATION | ACTIVATION | COMPLEX | PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | INTERACTS | PRODUCT | RECEPTORS | ASSOCIATION | NHERF1/EBP50 | REVEALS
Journal Article
RSC Advances, ISSN 2046-2069, 2015, Volume 5, Issue 102, pp. 84164 - 84171
NHERF1 might play a significant role in biological processes including oncogenic transformation and metastasis. Owing to the lack of highly sensitive and... 
BREAST-CANCER | GLIOBLASTOMA | SCAFFOLDING PROTEIN NHERF1 | COLORECTAL-CANCER | GROWTH | PTEN | HOMOGENEOUS IMMUNOASSAY | REGULATORY FACTOR-1 NHERF1 | EXPRESSION | CONTRIBUTES | CHEMISTRY, MULTIDISCIPLINARY
Journal Article
Journal Article
Oncology Reports, ISSN 1021-335X, 08/2018, Volume 40, Issue 2, pp. 1165 - 1173
NHERF1 is downregulated and has been identified as a new marker of colorectal cancer. However, the molecular mechanism of NHERF1 downregulation in colon cancer... 
DNMT1 | Wnt signaling | Colon cancer | NHERF1 | Methylation | CELLS | EBP50 | colon cancer | BETA-CATENIN | NUCLEAR NHERF1 | HEPATOCELLULAR-CARCINOMA | EZRIN | ONCOLOGY | methylation | COLORECTAL-CANCER | ESTROGEN | SCAFFOLD PROTEIN | CONTRIBUTES
Journal Article
Journal of Experimental and Clinical Cancer Research, ISSN 1756-9966, 05/2018, Volume 37, Issue 1, pp. 96 - 16
Background: Tumor microenvironment (TME) includes many factors such as tumor associated inflammatory cells, vessels, and lymphocytes, as well as different... 
Tissue microarray | Breast cancer | Immunohistochemical | NHERF1 | Tumor microenvironment | CANCER-CELLS | VASCULOGENIC MIMICRY | METASTASIS | ANGIOGENESIS | TWIST | EPITHELIAL-MESENCHYMAL TRANSITION | NUCLEAR NHERF1 | ONCOLOGY | GASTRIC-CANCER | COLORECTAL-CANCER | PROGRESSION | Physiological aspects | Development and progression | Genetic aspects | Research | Gene expression
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 2, pp. 607 - 620.e15
Background Patients with heterozygous germline mutations in phosphatase and tensin homolog deleted on chromosome 10 (PTEN) experience autoimmunity and lymphoid... 
Allergy and Immunology | PHTS | autoimmunity | immunologic synapse | PTEN | Regulatory T cells | phosphatases | phosphoinositide 3-kinase | PH domain leucine-rich repeat protein phosphatase | HOMEOSTASIS | PROTEIN | KINASE | PROMOTER MUTATIONS | RILEY-RUVALCABA-SYNDROME | IMMUNOLOGY | ALLERGY | RESOLUTION MELTING ANALYSIS | AKT-MTOR | LYMPHOID HYPERPLASIA | EXPRESSION | Autoimmunity | Humans | Hyperplasia | Middle Aged | Phosphoprotein Phosphatases - metabolism | Male | Immunological Synapses - metabolism | Young Adult | Forkhead Transcription Factors - metabolism | Membrane Potential, Mitochondrial | Adult | Child | Hamartoma Syndrome, Multiple - immunology | Lymphocyte Subsets - physiology | T-Lymphocytes, Regulatory - physiology | PTEN Phosphohydrolase - genetics | Hamartoma Syndrome, Multiple - genetics | Signal Transduction | Cells, Cultured | B-Lymphocytes - physiology | PTEN Phosphohydrolase - metabolism | Nuclear Proteins - metabolism | Mutation - genetics | Protein Transport | Adolescent | Protein Binding | Aged | Medical colleges | Care and treatment | Phosphatases | Gene mutations | Analysis | Children's hospitals | Genomics | Medical genetics | Genetic research | T cells | Tumors | Hamartoma | Proteins | Blood & organ donations | Hematology | Biopsy | Lymphocytes | T cell receptors | Mutation | Kinases | Metabolism | Phosphatase | FACS, Fluorescence-activated cell sorting | TCR, T-cell receptor | mTOR complex 1 | NHERF1, Na+ | H+-exchanger 3 regulatory factor | MALT, Mucosa-associated lymphoid tissue | APC, Allophycocyanin | SHIP, Src homology domain 2–containing inositol phosphatase | HRM, High Resolution DNA Melting | FITC, Fluorescein isothiocyanate | PP2A, Protein phosphatase 2A | mTORC1, PTEN | PHTS, PTEN hamartoma tumor syndrome | PerCP, Peridinin-chlorophyll-protein complex | CS, Cowden syndrome | POD, Peroxidase | Tmem, Memory T | TMRE, Tetramethylrhodamine-ethylester | Immune Deficiencies, Infection, and Systemic Immune Disorders | IC50, Inhibitory concentration of 50 | CTLA-4, Cytotoxic T lymphocyte–associated antigen 4 | PHLPP, PH domain leucine-rich repeat protein phosphatase | AKT | DLG1, Scaffold protein discs, large homolog 1 | FOXP3, Forkhead box P3 | ICAM-1, Intercellular adhesion molecule 1 | iTreg, In vitro induced regulatory T | PE, Phycoerythrin | PI3K, Phosphoinositide 3-kinase | mTOR, Mammalian target of rapamycin | PTEN, Phosphatase and tensin homologue deleted on chromosome 10
Journal Article
Translational Oncology, ISSN 1936-5233, 04/2018, Volume 11, Issue 2, pp. 374 - 390
Na /H exchanger regulatory factor 1 (NHERF1) is a scaffold protein, with two tandem PDZ domains and a carboxyl-terminal ezrin-binding (EB) region. This... 
TUMOR-INFILTRATING LYMPHOCYTES | REDUCED EBP50 EXPRESSION | BREAST-CANCER | NUCLEAR NHERF1 | EXCHANGER REGULATORY FACTOR-1 | ONCOLOGY | COLORECTAL-CANCER | PANCREATIC-CANCER | PROTEIN NHERF1 | CXCR2 MACROMOLECULAR COMPLEX | BINDING PHOSPHOPROTEIN 50
Journal Article
RSC Advances, 01/2015, Volume 5, Issue 102, pp. 84164 - 84171
NHERF1 might play a significant role in biological processes including oncogenic transformation and metastasis. Owing to the lack of highly sensitive and... 
Human | Lungs | Linearity | Tools | Assaying | Beads | Patients | Cancer
Journal Article
Arteriosclerosis, Thrombosis, and Vascular Biology, ISSN 1079-5642, 01/2012, Volume 32, Issue 1, pp. 33 - 41
OBJECTIVE—The Ezrin-radixin–moesin–binding phosphoprotein 50 (EBP50) is a scaffolding protein known to regulate ion homeostasis in the kidney and intestine.... 
smooth muscle | NHERF1 | p21cip1 | proliferation | EBP50 | Skp2
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 01/2019, Volume 509, Issue 1, pp. 8 - 15
NHERF1/EBP50 is a PDZ-scaffold protein initially identified as an organizer and modulator of transporters and channels at the apical side of epithelia via... 
Liver cancer | NHERF1 | G0/G1 phase | ROS production | Apoptosis | ACTIVATION | PHOSPHORYLATION | MARKER | BIOCHEMISTRY & MOLECULAR BIOLOGY | HCC | INDUCTION | BIOPHYSICS | PATHWAY | POOR-PROGNOSIS | EXPRESSION
Journal Article