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American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 08/2016, Volume 311, Issue 2, pp. G210 - G220
We tested the hypothesis that colonic enteric neurotransmission and smooth muscle cell (SMC) function are altered in mice fed a high-fat diet (HFD). We used... 
channel | Obesity | Enteric nervous system | Gastrointestinal motility | Large conductance calcium-activated K | gastrointestinal motility | OXIDATIVE STRESS | PHYSIOLOGY | BETA-1 SUBUNIT | GASTROINTESTINAL-TRACT | SMALL-INTESTINE | ACTIVATED POTASSIUM CHANNELS | KNOCKOUT MICE | PROTEIN S-NITROSYLATION | INTERSTITIAL-CELLS | INHIBITORY NEUROTRANSMISSION | large conductance calcium-activated K+ channel | MYENTERIC NEURONS | enteric nervous system | GASTROENTEROLOGY & HEPATOLOGY | obesity | Neural Inhibition | Oxidative Stress | Neuromuscular Junction - metabolism | Colon - innervation | Large-Conductance Calcium-Activated Potassium Channel beta Subunits - deficiency | Myenteric Plexus - metabolism | Myoelectric Complex, Migrating | Synaptic Transmission | Action Potentials | Gastrointestinal Motility | Diet, High-Fat | Obesity - etiology | Disease Models, Animal | Large-Conductance Calcium-Activated Potassium Channel beta Subunits - genetics | Muscle, Smooth - innervation | Mice, Inbred C57BL | Nitrergic Neurons - metabolism | Genotype | Obesity - physiopathology | Neuromuscular Junction - physiopathology | Mice, Knockout | Obesity - metabolism | Myenteric Plexus - physiopathology | Phenotype | Animals | Kinetics | Nitric Oxide - metabolism | Nitric oxide | Physiological aspects | Smooth muscle | Colon (Anatomy) | Health aspects | Ketogenic diet | Oils & fats | Colon | Diet | Rodents | Neurogastroenterology and Motility
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 07/2010, Volume 299, Issue 1, pp. G158 - G169
Gil V, Gallego D, Grasa L, Martin MT, Jimenez M. Purinergic and nitrergic neuromuscular transmission mediates spontaneous neuronal activity in the rat colon.... 
receptors | Gastrointestinal | Spontaneous inhibitory junction potential | Nitric oxide | P2Y | GUINEA-PIG ILEUM | nitric oxide | PHYSIOLOGY | spontaneous inhibitory junction potential | MOUSE COLON | P2Y receptors | SMALL-INTESTINE | gastrointestinal | CIRCULAR MUSCLE | DISTAL-COLON | CIRCUMFERENTIAL STRETCH | MYENTERIC NEURONS | NITRIC-OXIDE | SMOOTH-MUSCLE-CELLS | RHYTHMIC MOTOR PATTERN | GASTROENTEROLOGY & HEPATOLOGY | Neural Inhibition | Gastrointestinal Motility - drug effects | Nitric Oxide Synthase - antagonists & inhibitors | Colon - innervation | Male | Receptors, Purinergic P2Y1 | Myenteric Plexus - metabolism | Nicotinic Antagonists - pharmacology | Anesthetics, Local - pharmacology | Nitric Oxide Synthase Type I | Adenosine Triphosphate - metabolism | Inhibitory Postsynaptic Potentials | Potassium Channel Blockers - pharmacology | Deoxyadenine Nucleotides - pharmacology | Muscle, Smooth - innervation | Enzyme Inhibitors - pharmacology | Myenteric Plexus - drug effects | Nitrergic Neurons - metabolism | Purinergic P2 Receptor Antagonists | Rats | Serotonin 5-HT3 Receptor Antagonists | Serotonin Antagonists - pharmacology | Rats, Sprague-Dawley | Nitroarginine - pharmacology | Animals | Receptors, Purinergic P2 - metabolism | Receptors, Serotonin, 5-HT3 - metabolism | Nitric Oxide Synthase - metabolism | Muscle Relaxation - drug effects | Nitric Oxide - metabolism | Junctional complexes (Epithelium) | Gastrointestinal system | Cell junctions | Research | Neuromuscular transmission | Properties | Health aspects | Neurotransmitters | Rodents | Physiology | Colon | Muscular system | Adenosine triphosphatase
Journal Article
Journal of Veterinary Science, ISSN 1229-845X, 06/2006, Volume 7, Issue 2, pp. 143 - 150
Journal Article
The Journal of Physiology, ISSN 0022-3751, 03/2017, Volume 595, Issue 6, pp. 2021 - 2041
The internal anal sphincter develops tone important for maintaining high anal pressure and continence. Controversy exists regarding the mechanisms underlying... 
gastrointestinal motility | calcium‐activated chloride channels | excitation‐contraction coupling | interstitial cells of Cajal | calcium-activated chloride channels | excitation-contraction coupling | INTRACELLULAR CA2 | PHYSIOLOGY | PACEMAKER ACTIVITY | GASTROINTESTINAL-TRACT | MURINE SMALL-INTESTINE | NITRERGIC NEUROMUSCULAR-TRANSMISSION | FUNCTIONAL-ROLE | SMOOTH-MUSCLE-CELLS | GUINEA-PIG | NEUROSCIENCES | LOWER ESOPHAGEAL | CANINE RECTOANAL REGION | Anoctamin-1 | Interstitial Cells of Cajal - physiology | Male | Chloride Channels - genetics | Proto-Oncogene Proteins c-kit - metabolism | Anal Canal - metabolism | Interstitial Cells of Cajal - metabolism | Female | Muscle, Smooth - physiology | Proto-Oncogene Proteins c-kit - genetics | Gene Expression | Mice, Inbred C57BL | Calcium Channels, L-Type - physiology | Mice, Transgenic | Muscle, Smooth - metabolism | Chloride Channels - metabolism | Animals | Calcium Channels, L-Type - genetics | Muscle Contraction | Proto-Oncogene Proteins c-kit - physiology | Anal Canal - physiology | Membrane Potentials | Calcium Channels, L-Type - metabolism | In Vitro Techniques | Chloride Channels - physiology | Fluorescence | Gene expression | Smooth muscle | Hypotheses | Colon | Gastrointestinal Motility | Alimentary | Research Paper | Cellular and Molecular Physiology | Smooth Muscle
Journal Article
Journal Article
by Lu, C and Lu, HL and Huang, X and Liu, SH and Zang, JY and Li, YJ and Chen, J and Xu, WX
JOURNAL OF NEUROGASTROENTEROLOGY AND MOTILITY, ISSN 2093-0879, 04/2019, Volume 25, Issue 2, pp. 316 - 331
Background/Aims Interstitial cells of Cajal (ICC) and their special calcium-activated chloride channel, anoctamin-1 (ANO1) play pivotal roles in regulating... 
INTESTINAL INFLAMMATION | ANO1 | Anoctamin-1 | Down-regulation | Nitric oxide synthase | NITRERGIC NEUROMUSCULAR-TRANSMISSION | CAJAL | GASTROINTESTINAL MOTILITY | Colitis | Interstitial cells of Cajal | GASTROENTEROLOGY & HEPATOLOGY | CLINICAL NEUROLOGY | Original | 내과학
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, p. e0134876
Telokin phosphorylation by cyclic GMP-dependent protein kinase facilitates smooth muscle relaxation. In this study we examined the relaxation of gastric fundus... 
RHO-ASSOCIATED KINASE | CA2+ SENSITIZATION | LIGHT-CHAIN PHOSPHATASE | MULTIDISCIPLINARY SCIENCES | GASTROINTESTINAL-TRACT | NITRIC-OXIDE | NITRERGIC NEUROMUSCULAR-TRANSMISSION | INDUCED RELAXATION | TARGETING SUBUNIT | MYOSIN PHOSPHATASE | INTERSTITIAL-CELLS | Carbachol - chemistry | Phosphorylation | Nitric Oxide Donors - chemistry | Gastric Fundus - drug effects | Nitric Oxide - chemistry | Mice, Inbred C57BL | Gastric Fundus - physiology | Male | Mice, Transgenic | Muscle Tonus - drug effects | Cyclic GMP-Dependent Protein Kinases - chemistry | Nitroprusside - chemistry | Peptide Fragments - chemistry | Animals | Cyclic GMP - analogs & derivatives | Muscle Contraction - drug effects | Cyclic GMP - chemistry | Myosin Light Chains - chemistry | Neurons - physiology | Muscle, Smooth - physiology | Mice | Muscle Relaxation - drug effects | Potassium Chloride - chemistry | Myosin-Light-Chain Kinase - chemistry | Smooth muscle | Comparative analysis | Muscle proteins | Myosin | Biomedical research | Biology | Kinases | Phosphatase | Contraction | Proteins | Signal transduction | Rodents | Cyclic GMP | Light | Physiology | Stomach | Contractility | Muscles | Muscle contraction | Potassium chloride | Medicine | Sodium nitroprusside | Sodium | Carbachol | Protein kinase | Nitric oxide | Regulation | Laboratory animals | Neurotransmission
Journal Article