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Journal Article
Circulation, ISSN 0009-7322, 10/2007, Volume 116, Issue 16, pp. 1821 - 1831
Background - The recent discovery that nitrite is an intrinsic vasodilator and signaling molecule at near-physiological concentrations has raised the... 
Hemoglobin | Endothelium-derived factors | Free radicals | Nitric oxide | Nitroglycerin | OXIDE SYNTHASE ACTIVITY | free radicals | nitric oxide | CARDIAC & CARDIOVASCULAR SYSTEMS | DIRECTLY ACTING VASODILATOR | SODIUM-NITRITE | REGIONAL BLOOD-FLOW | SIGNALING MOLECULE | hemoglobin | endothelium-derived factors | ISCHEMIA-REPERFUSION INJURY | PLASMA NITRITE | nitroglycerin | IN-VIVO | EMERGING BIOLOGY | PERIPHERAL VASCULAR DISEASE | CIRCULATING NITRITE | Vasodilator Agents - pharmacokinetics | Sodium Nitrite - administration & dosage | Humans | Macaca fascicularis | Endothelium, Vascular - drug effects | Male | Enzyme Inhibitors - administration & dosage | Regional Blood Flow - drug effects | Endocrine System - drug effects | Adult | Female | Xanthine Oxidase - metabolism | Oxidation-Reduction | Drug Tolerance | Hemoglobins - metabolism | Ascorbic Acid - administration & dosage | Oxypurinol - administration & dosage | Vasodilator Agents - blood | Animals | Sodium Nitrite - blood | Endothelium, Vascular - metabolism | Antioxidants - administration & dosage | Vasodilation - drug effects | Nitric Oxide - metabolism | Sodium Nitrite - pharmacokinetics | Vasodilator Agents - administration & dosage | Infusions, Intra-Arterial | Physiological aspects | Vascular endothelium | Dosage and administration | Research | Pharmacokinetics | Nitrites
Journal Article
Circulation Research, ISSN 0009-7330, 09/2005, Volume 97, Issue 7, pp. 618 - 628
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 02/2004, Volume 113, Issue 3, pp. 482 - 489
Recent studies suggest that mitochondrial aldehyde dehydrogenase (ALDH-2) plays a central role in the process of nitroglycerin (glyceryl trinitrate, GTN)... 
MEDICINE, RESEARCH & EXPERIMENTAL | CORONARY-ARTERY DISEASE | SUPEROXIDE ANION | SMOOTH-MUSCLE | ORGANIC NITRATES | ENDOTHELIAL DYSFUNCTION | NITRATE TOLERANCE | NITRIC-OXIDE | DEPENDENT PROTEIN-KINASE | GLYCERYL TRINITRATE | VASODILATOR-STIMULATED PHOSPHOPROTEIN
Journal Article
Circulation Research, ISSN 0009-7330, 11/2006, Volume 99, Issue 10, pp. 1067 - 1075
Journal Article
Clinical Pharmacology & Therapeutics, ISSN 0009-9236, 01/2019, Volume 105, Issue 1, pp. 201 - 209
Development of nitrate tolerance is a major drawback to nitrate therapy. Prostacyclin (PGI2) is a powerful vasodilator produced from prostaglandin (PGH2) by... 
SOLUBLE GUANYLYL CYCLASE | OXIDATIVE STRESS | SUPEROXIDE | ACTIVATED PROTEIN-KINASE | THERAPY | INHIBITION | ENDOTHELIAL DYSFUNCTION | NITROGLYCERIN TOLERANCE | PEROXYNITRITE | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY
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Journal Article
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