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Clinical Cancer Research, ISSN 1078-0432, 08/2014, Volume 20, Issue 15, pp. 4096 - 4106
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 5/2016, Volume 113, Issue 21, pp. E2973 - E2982
Journal Article
Gastroenterology, ISSN 0016-5085, 2017, Volume 153, Issue 4, pp. 980 - 987
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 09/2018, Volume 503, Issue 4, pp. 2807 - 2813
The regulation of natural killer (NK) cell activity is an important research goal for the development of immunotherapies. In this study, we identified... 
Transforming growth factor-beta | Interleukin-2 | Natural killer cells | c-Myb | Celastrol | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | CANCER | AUTOREGULATION | GROWTH-FACTOR-BETA | BIOPHYSICS | GENE | IMMUNOTHERAPY | INHIBITOR | EXPRESSION | RNA, Small Interfering - genetics | Triterpenes - pharmacology | Humans | Proto-Oncogene Proteins c-myb - antagonists & inhibitors | NK Cell Lectin-Like Receptor Subfamily K - immunology | Proto-Oncogene Proteins c-myb - genetics | Intracellular Signaling Peptides and Proteins - immunology | Granzymes - genetics | Killer Cells, Natural - immunology | Granzymes - immunology | Interferon-gamma - genetics | Cytotoxicity, Immunologic - drug effects | Intracellular Signaling Peptides and Proteins - genetics | Cell Line | Signal Transduction | Gene Expression Regulation | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins c-myc - immunology | Proto-Oncogene Proteins c-myb - immunology | NK Cell Lectin-Like Receptor Subfamily K - genetics | Killer Cells, Natural - cytology | Transforming Growth Factor beta - pharmacology | Lymphocyte Activation - drug effects | Interferon-gamma - immunology | Interleukin-2 - pharmacology | Protein-Serine-Threonine Kinases - immunology | Cell Proliferation - drug effects | Killer Cells, Natural - drug effects | Proto-Oncogene Proteins c-myc - genetics | Primary Cell Culture | Immunologic Factors - pharmacology | RNA, Small Interfering - metabolism | Virus diseases | Medical colleges | Killer cells | Interleukins | Microbiology | Immunotherapy | Bone morphogenetic proteins | DNA binding proteins | Transforming growth factors | Index Medicus
Journal Article
Oncotarget, ISSN 1949-2553, 2015, Volume 6, Issue 42, pp. 44151 - 44160
Genetic deficiencies provide insights into gene function in humans. Here we describe a patient with a very rare genetic deficiency of ADAM17. We show that the... 
NK cells | Immune response | CD16 | ADAM17 deficiency | Immunology and microbiology section | ADCC | Immunity | Index Medicus
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 3, pp. 997 - 1006.e10
Journal Article
Journal Article
Anticancer research, ISSN 0250-7005, 2014, Volume 34, Issue 8, pp. 3975 - 3979
Background/Aim: Myricetin is a flavanoid that can be found in a variety of food sources, including red wine. Several reports have indicated that flavonoids may... 
Polyphenols | Cytotoxicity | NK-cells | Myricetin | Quercetin | polyphenols | ACTIVATION | MOUSE | CANCER | NKG2D | NK CELLS | ONCOLOGY | CYTOTOXICITY RECEPTORS | LINE | quercetin | cytotoxicity | Dose-Response Relationship, Drug | Killer Cells, Natural - immunology | Flavonoids - pharmacology | Killer Cells, Natural - drug effects | Humans | K562 Cells | Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, pp. e0175793 - e0175793
Hepatitis C virus (HCV) infection is characterized by a high frequency of chronic cases owing to the impairment of innate and adaptive immune responses. The... 
INHIBITORY RECEPTOR GENES | NK CELLS | MULTIDISCIPLINARY SCIENCES | INNATE | INFECTION | ADAPTIVE IMMUNE-RESPONSES | CYTOTOXICITY | EXPRESSION | CANCER | T-CELLS | NKP30 | Macrocyclic Compounds - chemistry | Interleukin-12 - genetics | Coculture Techniques | Humans | Natural Cytotoxicity Triggering Receptor 3 - metabolism | Interferon-gamma - metabolism | Natural Cytotoxicity Triggering Receptor 3 - genetics | Recombinant Proteins - biosynthesis | Carbamates - chemistry | Quinolines - pharmacology | Macrocyclic Compounds - pharmacology | Recombinant Proteins - isolation & purification | Hepatitis C - immunology | Serine Proteinase Inhibitors - chemistry | Natural Cytotoxicity Triggering Receptor 1 - genetics | Killer Cells, Natural - immunology | Serine Proteinase Inhibitors - pharmacology | Carbamates - pharmacology | Interleukin-12 - pharmacology | Cell Line | Cell Survival - drug effects | Quinolines - chemistry | Viral Nonstructural Proteins - genetics | Interleukin-12 - metabolism | Recombinant Proteins - pharmacology | Down-Regulation - drug effects | Microscopy, Confocal | Hepacivirus - enzymology | Interferon-gamma - analysis | Hepatitis C - virology | K562 Cells | Natural Cytotoxicity Triggering Receptor 1 - metabolism | Thiazoles - chemistry | Viral Nonstructural Proteins - metabolism | Killer Cells, Natural - drug effects | Thiazoles - pharmacology | Hepatitis C - pathology | Killer Cells, Natural - metabolism | Viral Nonstructural Proteins - antagonists & inhibitors | Physiological aspects | Killer cells | Genetic aspects | Research | Hepatitis C virus | Proteases | Cell culture | Flow cytometry | Target recognition | Serine | Science | Chronic infection | Cytotoxicity | Viruses | Infections | Negative selection | Proteins | Hepatitis | Immunology | Gastroenterology | Penicillin | Tumor necrosis factor-TNF | Natural killer cells | Enzyme-linked immunosorbent assay | Deoxyribonucleic acid--DNA | Immune response | Cytokines | T cell receptors | Virology | Medicine | Brain research | Degranulation | Ligands | Serine proteinase | Interferon | Nonstructural proteins | Hepatitis C | Viral infections | Index Medicus | Deoxyribonucleic acid | DNA
Journal Article
The Journal of allergy and clinical immunology, ISSN 0091-6749, 3/2017, Volume 139, Issue 3, pp. 997 - 1006.e10
Journal Article
Journal of Functional Foods, ISSN 1756-4646, 09/2018, Volume 48, pp. 153 - 158
The aim of this study was to investigate the impact of consuming ( ) JW15 on natural killer (NK) cell activity, cytokines and immunoglobulins (Igs). This... 
Probiotics | Immune function | Weissella cibaria JW15 | NK cell activity | LEUCONOSTOC | IMMUNITY | FOOD SCIENCE & TECHNOLOGY | PRIMERS | INTERLEUKIN-12 | ELDERLY-PEOPLE | HUMAN FECES | Weissella ciboria JW15 | NK CELLS | COMMUNITY | LACTIC-ACID BACTERIA | LACTOBACILLUS
Journal Article
Oncotarget, ISSN 1949-2553, 2017, Volume 8, Issue 38, pp. 64344 - 64357
Using syngeneic BALB/c mouse breast cancer models, we show that the chromatin remodeling subunit bromodomain PHD finger transcription factor (BPTF) suppresses... 
Heparanase | Antitumor immunity | NK cell | BPTF | Chromatin remodeling | ACTIVATION | PROTEIN | METASTASIS | RECOGNITION | chromatin remodeling | heparanase | antitumor immunity | TUMORS | CELL BIOLOGY | RESPONSES | IMPACT | ABSENCE | NKP46 | NURF
Journal Article
Journal Article
Journal of Virology, ISSN 0022-538X, 2015, Volume 89, Issue 12, pp. 6435 - 6441
Control of human cytomegalovirus (HCMV) requires a continuous immune surveillance, thus HCMV is the most important viral pathogen in severely immunocompromised... 
REPERTOIRE | VIRUS | VIROLOGY | ERYTHROCYTES | IMMUNE-RESPONSES | IFN-GAMMA | VACCINATION | RECEPTOR | HUMAN NK CELLS | DEPENDENT ACTIVATION | HLA-E | CD4-Positive T-Lymphocytes - immunology | Macrophages - virology | Humans | Cells, Cultured | Killer Cells, Natural - immunology | Cytomegalovirus Infections - immunology | Interleukin-2 - secretion | Index Medicus
Journal Article