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Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 443 - 456
The mechanisms underlying human natural killer (NK) cell phenotypic and functional heterogeneity are unknown. Here, we describe the emergence of diverse... 
NATURAL-KILLER-CELLS | ACTIVATION | CMV REACTIVATION | INNATE | RECEPTOR | FCR-GAMMA | DIFFERENTIATION | IMMUNOLOGY | PLZF CONTROLS | EXPRESSION | T-CELLS | Cell Proliferation | Humans | Transcription Factors - deficiency | NK Cell Lectin-Like Receptor Subfamily C - genetics | Receptors, IgG - deficiency | Intracellular Signaling Peptides and Proteins - immunology | Cytomegalovirus Infections - immunology | Gene Expression Profiling | Killer Cells, Natural - pathology | Cytomegalovirus Infections - genetics | Protein-Tyrosine Kinases - deficiency | Protein-Tyrosine Kinases - immunology | T-Lymphocytes, Cytotoxic - pathology | Intracellular Signaling Peptides and Proteins - deficiency | NK Cell Lectin-Like Receptor Subfamily C - immunology | DNA Methylation | Protein-Tyrosine Kinases - genetics | Receptors, IgG - genetics | Microarray Analysis | Antibodies - immunology | Cytomegalovirus Infections - virology | Killer Cells, Natural - immunology | Cytomegalovirus Infections - pathology | Kruppel-Like Transcription Factors - deficiency | Transcription Factors - immunology | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Adaptive Immunity | T-Lymphocytes, Cytotoxic - immunology | Promoter Regions, Genetic | GPI-Linked Proteins - immunology | Signal Transduction | Killer Cells, Natural - virology | T-Lymphocytes, Cytotoxic - virology | NK Cell Lectin-Like Receptor Subfamily C - deficiency | Immunophenotyping | Receptors, IgG - immunology | Transcription Factors - genetics | Killer Cells, Natural - classification | Promyelocytic Leukemia Zinc Finger Protein | Cytomegalovirus - immunology | Epigenesis, Genetic - immunology | Kruppel-Like Transcription Factors - genetics | Kruppel-Like Transcription Factors - immunology | GPI-Linked Proteins - genetics | Virus diseases | Proteins | Epigenetic inheritance | Killer cells | Immunotherapy | Genomics | Medical genetics | Cytomegalovirus infections | T cells | Methylation | Health aspects | Antigens | Flow cytometry | Cytomegalovirus | Data analysis | Biomedical research | Transplants & implants | Cytokines | Leukemia | Cytotoxicity | Infections | Kinases | Diversification | Gene expression | Experiments | Scholarships & fellowships | Lymphocytes | DNA methylation | Epigenetics | Viral infections | Immune system | Cancer | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 03/2015, Volume 42, Issue 3, pp. 431 - 442
Long-lived “memory-like” NK cells have been identified in individuals infected by human cytomegalovirus (HCMV), but little is known about how the memory-like... 
ADAPTIVE IMMUNITY | CD94/NKG2C RECEPTOR | REPERTOIRE | NATURAL-KILLER-CELLS | ACTIVATION | TYROSINE KINASE | FCR-GAMMA | UMBILICAL-CORD BLOOD | DIFFERENTIATION | IMMUNOLOGY | CHILDREN | Cell Proliferation | Humans | NK Cell Lectin-Like Receptor Subfamily C - genetics | Receptors, IgG - deficiency | Intracellular Signaling Peptides and Proteins - immunology | Cytomegalovirus Infections - immunology | Gene Expression Profiling | Killer Cells, Natural - pathology | Cytomegalovirus Infections - genetics | Protein-Tyrosine Kinases - deficiency | Protein-Tyrosine Kinases - immunology | Intracellular Signaling Peptides and Proteins - deficiency | NK Cell Lectin-Like Receptor Subfamily C - immunology | DNA Methylation | Protein-Tyrosine Kinases - genetics | Receptors, IgG - genetics | Microarray Analysis | Antibodies - immunology | Cytomegalovirus Infections - virology | Killer Cells, Natural - immunology | Cytomegalovirus Infections - pathology | Intracellular Signaling Peptides and Proteins - genetics | Syk Kinase | Promoter Regions, Genetic | GPI-Linked Proteins - immunology | Signal Transduction | Killer Cells, Natural - virology | NK Cell Lectin-Like Receptor Subfamily C - deficiency | Immunophenotyping | Receptors, IgG - immunology | Killer Cells, Natural - classification | Cytomegalovirus - immunology | Epigenesis, Genetic - immunology | Immunologic Memory | GPI-Linked Proteins - genetics | Proteins | Viral antibodies | Epigenetic inheritance | Killer cells | Molecular genetics | Antibodies | Gene expression | Antigens | Cytomegalovirus | Cloning | Colleges & universities | Infections | Experiments | Long term | DNA methylation | Epigenetics | Expansion | Viral infections | Deoxyribonucleic acid--DNA | Immune system | Index Medicus
Journal Article
Journal Article
Journal of Leukocyte Biology, ISSN 0741-5400, 01/2017, Volume 101, Issue 1, pp. 329 - 338
The liver contains 2 transcriptionally distinct group 1 ILC subsets: CD49a + ILC1s and CD49b + NK cells. However, little is known about how group 1 ILCs... 
T lymphocytes | natural killer cells | viruses | immunity | Viruses | Natural killer cells | Immunity | NATURAL-KILLER-CELLS | DENDRITIC CELLS | PROTECTION | SUBSETS | IMMUNOLOGY | CELL BIOLOGY | ADAPTIVE IMMUNITY | NK CELLS | INFLAMMATION | INFECTION | DIFFERENTIATION | HEMATOLOGY | HEPATITIS-C | Antiviral Agents - immunology | Cell Count | Chemokine CXCL9 - biosynthesis | Integrin alpha1 - metabolism | Male | Interferon-gamma - metabolism | Antigens, CD - metabolism | Epitopes - immunology | Chemotactic Factors - pharmacology | Killer Cells, Natural - immunology | Dendritic Cells - drug effects | Female | Cell Membrane - metabolism | Cell Membrane - drug effects | Dendritic Cells - metabolism | NK Cell Lectin-Like Receptor Subfamily C - metabolism | Immunity, Innate - drug effects | NK Cell Lectin-Like Receptor Subfamily C - deficiency | Integrin alpha Chains - metabolism | Lymphocytes - cytology | Animals | Cross-Priming - immunology | CD8-Positive T-Lymphocytes - drug effects | Lymphocytes - drug effects | Liver - cytology | Mice | Adenoviridae - metabolism | CD8-Positive T-Lymphocytes - immunology | Cell proliferation | Antiviral agents | Lymphoid cells | Immune response | Transcription | Dendritic cells | CD8 antigen | Liver | Priming | Infections | Lymphocytes T | Adaptive immunity | Vaccines | Recruitment | NKG2 antigen | Signaling | CD103 antigen | Hepatocytes | Lymphocytes | γ-Interferon | Interferon | Viral infections | Index Medicus | Inflammation, Extracellular Mediators, & Effector Molecules
Journal Article
The Journal of Immunology, ISSN 0022-1767, 01/2009, Volume 182, Issue 1, pp. 250 - 258
Activation of invariant NKT (iNKT) cells in the liver is generally regarded as the critical step for Con A-induced hepatitis, and the role of NK cell receptors... 
CYTOKINE PRODUCTION | A-INDUCED HEPATITIS | MEDIATED CYTOTOXICITY | MOLECULE QA-1(B) | ALPHA-GALACTOSYLCERAMIDE | IFN-GAMMA | BONE-MARROW | IN-VIVO | KILLER T-CELLS | IMMUNOLOGY | TUMOR-IMMUNITY | Concanavalin A - toxicity | NK Cell Lectin-Like Receptor Subfamily C - genetics | NK Cell Lectin-Like Receptor Subfamily C - immunology | Signal Transduction - immunology | Lymphocyte Activation - immunology | Melanoma, Experimental - immunology | Natural Killer T-Cells - metabolism | Natural Killer T-Cells - pathology | Growth Inhibitors - biosynthesis | Mice, Inbred DBA | NK Cell Lectin-Like Receptor Subfamily D - antagonists & inhibitors | Chemical and Drug Induced Liver Injury - pathology | Growth Inhibitors - genetics | Cell Line | Antibodies, Monoclonal - pharmacology | Concanavalin A - administration & dosage | Mice, Inbred C57BL | NK Cell Lectin-Like Receptor Subfamily C - deficiency | Receptors, Antigen, T-Cell - physiology | Chemical and Drug Induced Liver Injury - immunology | Mice, Knockout | Animals | NK Cell Lectin-Like Receptor Subfamily C - physiology | Chemical and Drug Induced Liver Injury - metabolism | Down-Regulation - immunology | NK Cell Lectin-Like Receptor Subfamily D - physiology | Growth Inhibitors - physiology | Mice | Natural Killer T-Cells - immunology | Index Medicus | Abridged Index Medicus
Journal Article
PLoS ONE, ISSN 1932-6203, 10/2013, Volume 8, Issue 10, pp. e76781 - e76781
Natural killer (NK) cells are important mediators of anti-tumor immunity and are active against several hematologic malignancies, including multiple myeloma... 
EX-VIVO EXPANSION | MULTIPLE-MYELOMA | NK CELLS | UNRELATED DONOR | MULTIDISCIPLINARY SCIENCES | BONE-MARROW | AUTOLOGOUS TRANSPLANTATION | TERM-FOLLOW-UP | IMMUNOLOGICAL SYNAPSE FORMATION | ANTITUMOR-ACTIVITY | T-LYMPHOCYTES | Cell Proliferation | Coculture Techniques | Humans | Multiple Myeloma - immunology | Interleukin Receptor Common gamma Subunit - immunology | NK Cell Lectin-Like Receptor Subfamily D - immunology | NK Cell Lectin-Like Receptor Subfamily C - immunology | Multiple Myeloma - therapy | Interleukin-2 - immunology | Killer Cells, Natural - immunology | Cell Culture Techniques | CD56 Antigen - immunology | Cytotoxicity, Immunologic - drug effects | CD56 Antigen - metabolism | Fetal Blood - immunology | NK Cell Lectin-Like Receptor Subfamily C - metabolism | Cells, Cultured | Fetal Blood - cytology | Fetal Blood - metabolism | Mice, SCID | Xenograft Model Antitumor Assays - methods | Antigen-Presenting Cells - immunology | CD3 Complex - metabolism | Interleukin Receptor Common gamma Subunit - genetics | Mice, Knockout | Interleukin Receptor Common gamma Subunit - deficiency | Microscopy, Confocal | Multiple Myeloma - pathology | Animals | CD3 Complex - immunology | K562 Cells | Cell Line, Tumor | Interleukin-2 - pharmacology | Mice, Inbred NOD | Mice | Killer Cells, Natural - metabolism | Cytotoxicity, Immunologic - immunology | NK Cell Lectin-Like Receptor Subfamily D - metabolism | Antigens | Killer cells | Cell culture | Pediatrics | Transcription factors | Transplants & implants | Toxicity | Leukemia | Multiple myeloma | Cytotoxicity | Immunological synapses | Immunity | Blood | NKG2 antigen | Receptors | Interleukin 2 | Cord blood | Cryopreservation | Immunotherapy | Bone marrow | Biocompatibility | Natural killer cells | CD56 antigen | Expansion | Immunoglobulins | Cytokines | CD3 antigen | Permeability | Medicine | Studies | Stem cells | Ligands | Umbilical cord | Gene therapy | Synapses | Cancer | Index Medicus
Journal Article
Immunity, ISSN 1074-7613, 04/2008, Volume 28, Issue 4, pp. 571 - 580
Journal Article
Blood, ISSN 0006-4971, 2009, Volume 114, Issue 13, pp. 2657 - 2666
Journal Article