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Clinical & Experimental Immunology, ISSN 0009-9104, 05/2014, Volume 176, Issue 2, pp. 266 - 274
I nflammatory bowel diseases are characterized by a deregulated immune response targeting the gut bacterial flora. M ucosal‐associated invariant T ( MAIT )... 
immune system | MHC | class I‐like | cells | inflammatory bowel diseases | innate | Inflammatory bowel diseases | Innate T cells | MHC class I-like | Immune system | NATURAL-KILLER-CELLS | CYTOKINES | CROHNS-DISEASE | ULCERATIVE-COLITIS | IMMUNOLOGY | SUBSET | NKG2D | innate T cells | INFECTION | DEFINES | EXPRESSION | IMPROVES CYTOTOXICITY | T-Lymphocyte Subsets - immunology | Humans | Inflammatory Bowel Diseases - immunology | Interleukin-17 - immunology | NK Cell Lectin-Like Receptor Subfamily K - immunology | Ki-67 Antigen - metabolism | Male | Colitis, Ulcerative - immunology | Lymphocyte Activation - immunology | Flow Cytometry | Ki-67 Antigen - immunology | NK Cell Lectin-Like Receptor Subfamily K - metabolism | Intestinal Mucosa - immunology | Natural Killer T-Cells - metabolism | Inflammatory Bowel Diseases - pathology | Interleukins - immunology | Natural Killer T-Cells - pathology | Adult | Female | Receptors, Immunologic - immunology | Interleukin-17 - blood | Interleukins - blood | Colitis, Ulcerative - pathology | Inflammatory Bowel Diseases - blood | Colitis, Ulcerative - blood | Crohn Disease - immunology | Immunity, Innate - immunology | Microscopy, Confocal | T-Lymphocyte Subsets - pathology | Crohn Disease - pathology | T-Lymphocyte Subsets - metabolism | Crohn Disease - blood | Interferon-gamma - immunology | Interferon-gamma - blood | Receptors, Immunologic - metabolism | Intestinal Mucosa - pathology | Natural Killer T-Cells - immunology | Biological response modifiers | T cells | Analysis | Ulcerative colitis | Medical research | Bowel disease | Index Medicus | Original
Journal Article
PLoS Pathogens, ISSN 1553-7366, 04/2013, Volume 9, Issue 4, pp. e1003257 - e1003257
Journal Article
Blood, ISSN 0006-4971, 09/2011, Volume 118, Issue 12, pp. 3301 - 3310
CD3(+)CD56(+) cytokine-induced killer (CIK) cells display a potent cytolytic activity. The adhesion molecule lymphocyte function-associated antigen-1 plays a... 
IMMUNOLOGICAL EFFECTOR-CELLS | SEVERE COMBINED IMMUNODEFICIENCY | NKG2D | DENDRITIC CELLS | IN-VIVO | ANTITUMOR-ACTIVITY | NECTIN-2 CD112 | HEMATOLOGY | PHASE-I | INDUCED KILLER-CELLS | CELIAC-DISEASE | Neoplasms - metabolism | T-Lymphocyte Subsets - immunology | T-Lymphocyte Subsets - cytology | Humans | Natural Cytotoxicity Triggering Receptor 3 - metabolism | NK Cell Lectin-Like Receptor Subfamily K - immunology | Lymphocyte Function-Associated Antigen-1 - metabolism | Cytomegalovirus Infections - immunology | Cytomegalovirus Infections - metabolism | Lymphocyte Function-Associated Antigen-1 - immunology | Signal Transduction - immunology | T-Lymphocytes, Cytotoxic - drug effects | Flow Cytometry | NK Cell Lectin-Like Receptor Subfamily K - metabolism | Neoplasms - genetics | Cytomegalovirus Infections - virology | Killer Cells, Natural - immunology | Cytomegalovirus Infections - pathology | Natural Cytotoxicity Triggering Receptor 3 - immunology | CD56 Antigen - immunology | Cytotoxicity, Immunologic - drug effects | Antibodies, Monoclonal - immunology | T-Lymphocytes, Cytotoxic - immunology | Cytokine-Induced Killer Cells - metabolism | Antigens, Differentiation, T-Lymphocyte - immunology | Antibodies, Monoclonal - pharmacology | Antigens, Differentiation, T-Lymphocyte - metabolism | Cytokine-Induced Killer Cells - immunology | Cytomegalovirus - growth & development | Cytomegalovirus - immunology | Killer Cells, Natural - cytology | Signal Transduction - drug effects | Neoplasms - immunology | T-Lymphocyte Subsets - metabolism | CD3 Complex - immunology | Cell Line, Tumor | Cytokine-Induced Killer Cells - cytology | Killer Cells, Natural - metabolism | Primary Cell Culture | Neoplasms - pathology | Index Medicus | Abridged Index Medicus
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 1/2012, Volume 109, Issue 4, pp. 1210 - 1215
Journal Article
Science, ISSN 0036-8075, 03/2018, Volume 359, Issue 6383, pp. 1537 - 1542
Journal Article
Blood, ISSN 0006-4971, 07/2012, Volume 120, Issue 3, pp. 592 - 602
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 9/2014, Volume 111, Issue 35, pp. 12823 - 12828
Journal Article
Cancer Research, ISSN 0008-5472, 04/2014, Volume 74, Issue 8, pp. 2193 - 2203
The immunoreceptor NKG2D originally identified in natural killer (NK) cells recognizes ligands that are upregulated on tumor cells. Expression of NKG2D ligands... 
TRANSCRIPTION FACTORS | B-CELLS | DAMAGE RESPONSE | SIGNALING PATHWAYS | NATURAL-KILLER | INTERFERON | IMMUNE-SYSTEM | ONCOLOGY | IN-VIVO | C-MYC | INNATE | Immunologic Surveillance | Up-Regulation | Phosphorylation | Nucleocytoplasmic Transport Proteins - biosynthesis | DNA, Neoplasm - metabolism | NK Cell Lectin-Like Receptor Subfamily K - immunology | Interferon Regulatory Factor-3 - genetics | Lymphoma - metabolism | Transfection | DNA Damage - physiology | NK Cell Lectin-Like Receptor Subfamily K - metabolism | DNA Damage - genetics | Killer Cells, Natural - immunology | Membrane Proteins - metabolism | Protein-Serine-Threonine Kinases - metabolism | Interferon Regulatory Factor-3 - immunology | Nucleocytoplasmic Transport Proteins - immunology | Membrane Proteins - genetics | Nuclear Matrix-Associated Proteins - immunology | Mice, Inbred C57BL | Lymphoma - immunology | Protein-Serine-Threonine Kinases - genetics | Lymphoma - genetics | Nuclear Matrix-Associated Proteins - metabolism | Membrane Proteins - immunology | Mice, Transgenic | NK Cell Lectin-Like Receptor Subfamily K - genetics | Nucleocytoplasmic Transport Proteins - genetics | Animals | Nucleocytoplasmic Transport Proteins - metabolism | Nuclear Matrix-Associated Proteins - genetics | Cell Line, Tumor | Interferon Regulatory Factor-3 - metabolism | Ligands | Protein-Serine-Threonine Kinases - immunology | Mice | Killer Cells, Natural - metabolism | Nuclear Matrix-Associated Proteins - biosynthesis | DNA Damage - radiation effects | Index Medicus
Journal Article
Journal of Immunology, ISSN 0022-1767, 03/2015, Volume 194, Issue 6, pp. 2847 - 2854
NK cells are an important component of host immune defense against malignancy and infection. NK cells are educated by MHC class I ligands to ensure... 
ADAPTIVE IMMUNITY | REPERTOIRE | NATURAL-KILLER-CELLS | ACTIVATION | RESPONSIVENESS | INHIBITORY RECEPTORS | DIFFERENTIATION | IMMUNOLOGY | EXPRESSION | SELF-TOLERANCE | CUTTING EDGE | Self Tolerance - immunology | Inositol Polyphosphate 5-Phosphatases | Phosphoric Monoester Hydrolases - deficiency | NK Cell Lectin-Like Receptor Subfamily K - immunology | Interferon-gamma - metabolism | Mice, 129 Strain | Bone Marrow Transplantation - methods | Haptens - immunology | NK Cell Lectin-Like Receptor Subfamily D - immunology | Dermatitis, Contact - immunology | Flow Cytometry | Phosphoric Monoester Hydrolases - immunology | NK Cell Lectin-Like Receptor Subfamily K - metabolism | Natural Cytotoxicity Triggering Receptor 1 - genetics | Self Tolerance - genetics | Killer Cells, Natural - immunology | Natural Cytotoxicity Triggering Receptor 1 - immunology | Cytokines - immunology | Dermatitis, Contact - genetics | NK Cell Lectin-Like Receptor Subfamily A - metabolism | Phosphoric Monoester Hydrolases - genetics | Cytokines - metabolism | Mice, Inbred C57BL | Histocompatibility Antigens Class I - immunology | Homeostasis - immunology | Mice, Transgenic | NK Cell Lectin-Like Receptor Subfamily A - immunology | Histocompatibility - immunology | Mice, Knockout | Animals | Interferon-gamma - immunology | Natural Cytotoxicity Triggering Receptor 1 - metabolism | Graft Rejection - immunology | Killer Cells, Natural - metabolism | Graft Rejection - genetics | Phosphatidylinositol-3,4,5-Trisphosphate 5-Phosphatases | NK Cell Lectin-Like Receptor Subfamily D - metabolism | Homeostasis - genetics | Index Medicus | Abridged Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 10/2012, Volume 122, Issue 10, pp. 3718 - 3730
A promising strategy for cancer immunotherapy is to disrupt key pathways regulating immune tolerance, such as cytotoxic T lymphocyte-associated protein 4... 
BREAST-CANCER | MEDICINE, RESEARCH & EXPERIMENTAL | CTLA-4 BLOCKADE | LYMPHOCYTE ANTIGEN-4 | PHOSPHATIDYLINOSITOL 3-KINASE | IN-VIVO | COMBINATION IMMUNOTHERAPY | TUMOR-CELLS | NKG2D RECEPTOR | IMMUNOLOGICAL SYNAPSE | STOP-SIGNAL | Mammary Neoplasms, Experimental - immunology | Nucleocytoplasmic Transport Proteins - biosynthesis | NK Cell Lectin-Like Receptor Subfamily K - immunology | Antibodies, Monoclonal - therapeutic use | Cell Line, Tumor - transplantation | CD8-Positive T-Lymphocytes - radiation effects | Immunotherapy | Intercellular Adhesion Molecule-1 - biosynthesis | Female | Mammary Neoplasms, Experimental - secondary | Gene Expression Regulation, Neoplastic - drug effects | Neoplasm Proteins - genetics | Cytotoxicity, Immunologic - drug effects | Neoplasm Proteins - biosynthesis | Receptors, CXCR - genetics | Antibodies, Monoclonal - pharmacology | Mammary Neoplasms, Experimental - radiotherapy | Combined Modality Therapy | Lymphocytes, Tumor-Infiltrating - drug effects | Nucleocytoplasmic Transport Proteins - genetics | Mammary Neoplasms, Experimental - therapy | Tumor Microenvironment - immunology | H-2 Antigens - immunology | Animals | NK Cell Lectin-Like Receptor Subfamily K - antagonists & inhibitors | Nuclear Matrix-Associated Proteins - genetics | CD8-Positive T-Lymphocytes - drug effects | Cell Line, Tumor - immunology | Intercellular Adhesion Molecule-1 - genetics | Gene Expression Regulation, Neoplastic - radiation effects | Mice | Mice, Inbred BALB C | CD8-Positive T-Lymphocytes - immunology | CTLA-4 Antigen - antagonists & inhibitors | Nuclear Matrix-Associated Proteins - biosynthesis | Cytotoxicity, Immunologic - radiation effects | Lymphocytes, Tumor-Infiltrating - radiation effects | Cell Movement | Drug Screening Assays, Antitumor | Lymphocytes, Tumor-Infiltrating - immunology | Receptors, CXCR6 | Care and treatment | Tumor-infiltrating lymphocytes | Physiological aspects | Research | T cells | Health aspects | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Cytotherapy, ISSN 1465-3249, 2009, Volume 11, Issue 3, pp. 341 - 355
Background aims Cancer immunotherapy involving natural killer (NK) cell infusions and administration of therapeutic agents modulating the susceptibility of... 
Advanced Basic Science | Other | natural killer cells | Bortezomib | immunotherapy | expansion | Natural killer cells | Expansion | Immunotherapy | MEDICINE, RESEARCH & EXPERIMENTAL | EFFECTOR FUNCTIONS | NK-CELL | PROLIFERATION | TRANSPLANTATION | CELL & TISSUE ENGINEERING | CELL BIOLOGY | APOPTOSIS-INDUCING LIGAND | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | GENERATION | HEMATOLOGY | CYTOTOXICITY | LYMPHOCYTES | Up-Regulation | Fas Ligand Protein - metabolism | Immunotherapy - methods | Cell Proliferation | Humans | NK Cell Lectin-Like Receptor Subfamily K - immunology | Killer Cells, Natural - pathology | Carcinoma, Renal Cell - immunology | Fas Ligand Protein - immunology | NK Cell Lectin-Like Receptor Subfamily K - metabolism | Cryopreservation | Killer Cells, Natural - immunology | Cell Culture Techniques | Carcinoma, Renal Cell - drug therapy | Carcinoma, Renal Cell - pathology | Lymphocyte Activation | Cytokines - secretion | Immunophenotyping | TNF-Related Apoptosis-Inducing Ligand - immunology | NK Cell Lectin-Like Receptor Subfamily K - genetics | TNF-Related Apoptosis-Inducing Ligand - metabolism | K562 Cells | Killer Cells, Natural - metabolism | Cytotoxicity, Immunologic - immunology | Fas Ligand Protein - genetics | Pyrazines - pharmacology | TNF-Related Apoptosis-Inducing Ligand - genetics | Boronic Acids - pharmacology | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 01/2012, Volume 72, Issue 2, pp. 460 - 471
Journal Article