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Molecules (Basel, Switzerland), ISSN 1420-3049, 04/2019, Volume 24, Issue 8, p. 1548
Preeclampsia (PE) is a human pregnancy-specific syndrome with abnormal activation of cells from the innate immune system. The present study evaluated whether... 
NLRP1/NLRP3 inflammasomes | NF-κB | monocytes | preeclampsia | monosodium urate | silibinin
Journal Article
03/2012
Nlrp1b is a NOD-like receptor of the innate immune system that upon sensing of anthrax lethal toxin oliogmerizes and forms a protein scaffold that binds to and... 
FIIND | NOD | Microbiology | IL-1 | CARD8 | Nlrp1 | Inflammation | Lethal toxin | Inflammasome | Nalp1b | Nlrp1b | CARD | Innate immune | pyroptosis | Immunology | Proteolysis | Anthrax | 0410 | NLR | Cleavage | Cleaved | caspase-1 | Pattern recognition receptor
Dissertation
Pigment Cell & Melanoma Research, ISSN 1755-1471, 07/2012, Volume 25, Issue 4, pp. 506 - 513
Journal Article
Clinical Immunology, ISSN 1521-6616, 02/2018, Volume 187, pp. 46 - 49
Although inflammasome plays a well-known role in animal models of renal injury, limited studies in humans are available, and its participation in diabetic... 
SNPs | Inflammasome | NLRP1 | Type 1 diabetes | Diabetic kidney disease | SYSTEMIC-LUPUS-ERYTHEMATOSUS | POLYMORPHISMS | PREDISPOSITION | GENES | IMMUNOLOGY | NEPHROPATHY | Index Medicus
Journal Article
Journal Article
Journal of Acquired Immune Deficiency Syndromes, ISSN 1525-4135, 07/2010, Volume 54, Issue 3, pp. 236 - 240
Objectives: Innate immunity genes polymorphisms are known to be involved in the multifactorial susceptibility to HIV-1 infection. Recently it has been... 
HIV-1 | NALP3/NLRP3/CIAS1 | genetics | innate immunity | inflammasome | NALP1/NLRP1 | IL-1beta | polymorphisms | IMMUNITY | INFECTIOUS DISEASES | CCL3L1 | IMMUNOLOGY | NALP3 INFLAMMASOME | DISEASE
Journal Article
Immunity, ISSN 1074-7613, 12/2012, Volume 37, Issue 6, pp. 1009 - 1023
Cytopenias are key prognostic indicators of life-threatening infection, contributing to immunosuppression and mortality. Here we define a role for... 
NALP1 | LETHAL TOXIN | IN-VIVO | DISEASE | BINDING-PROTEIN | DEATH | INFECTION | IMMUNOLOGY | TIR DOMAIN | LYMPHOCYTIC CHORIOMENINGITIS VIRUS | CASPASE-1 ACTIVATION | Inflammasomes - metabolism | Cytoskeletal Proteins - genetics | Dermatitis - immunology | Pancytopenia - immunology | Caspase 1 - metabolism | Interferon-gamma - metabolism | Hematopoiesis - drug effects | Inflammation - metabolism | T-Lymphocytes - metabolism | Interleukin-1beta - metabolism | Apoptosis Regulatory Proteins - genetics | Cytoskeletal Proteins - metabolism | Hematopoietic Stem Cells - virology | Hematopoietic Stem Cells - drug effects | Hematopoietic Stem Cells - metabolism | Inflammation - immunology | Apoptosis Regulatory Proteins - metabolism | Mice, Knockout | Pancytopenia - metabolism | Hematopoiesis - immunology | Animals | CARD Signaling Adaptor Proteins | Adaptor Proteins, Signal Transducing - genetics | Inflammation - genetics | T-Lymphocytes - immunology | Fluorouracil - pharmacology | Mice | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Interleukin-18 - metabolism | Apoptosis | Dermatitis - metabolism | Chemotherapy | Research | Health aspects | Oncology, Experimental | Immunotherapy | Cancer | Proteins | Medical research | Disease | Councils | Bone marrow | Infections | Grants | Kinases | Index Medicus | pyroptosis | inflammasome | IL-18 | progenitor cells | NLRP1 | cytopenia | IL-1β | sepsis
Journal Article
Cell, ISSN 0092-8674, 09/2016, Volume 167, Issue 1, pp. 187 - 202.e17
Inflammasome complexes function as key innate immune effectors that trigger inflammation in response to pathogen- and danger-associated signals. Here, we... 
keratosis lichenoides chronica | germline | IL-1 | keratinocytes | multiple self-healing squamous cell carcinoma | ASC | gain-of-function | inflammasome | cancer | genodermatosis | NLRP1 | MSSE | MSPC | skin inflammation | APOPTOSIS | IMMUNITY | CELLS | DOMAIN | NALP1 | INTERLEUKIN-1-BETA | VITILIGO | BIOCHEMISTRY & MOLECULAR BIOLOGY | KERATINOCYTES | NLRC4 CAUSES | AUTOINFLAMMATORY DISEASE | CELL BIOLOGY | Adaptor Proteins, Signal Transducing - chemistry | Keratosis - genetics | Inflammasomes - metabolism | Pyrin - chemistry | Humans | Chromosomes, Human, Pair 17 - genetics | Hyperplasia - genetics | Apoptosis Regulatory Proteins - genetics | Germ-Line Mutation | Protein Domains | Keratosis - pathology | Carcinoma - pathology | Skin Neoplasms - pathology | Amino Acid Sequence | Interleukin-1 - metabolism | Epidermis - pathology | Genetic Predisposition to Disease | Paracrine Communication | Signal Transduction | Apoptosis Regulatory Proteins - chemistry | Inflammasomes - genetics | Syndrome | Hyperplasia - pathology | Pedigree | Skin Neoplasms - genetics | Adaptor Proteins, Signal Transducing - genetics | Carcinoma - genetics | Oligomers | Medical colleges | Gene mutations | Medical genetics | Disease susceptibility | Genetic aspects | Skin | Health aspects | Skin cancer | Proteins | Squamous cell carcinoma | Index Medicus
Journal Article
Cell Reports, ISSN 2211-1247, 12/2017, Volume 21, Issue 12, pp. 3427 - 3444
The caspase activation and recruitment domain (CARD)-based inflammasome sensors NLRP1b and NLRC4 induce caspase-1-dependent pyroptosis independent of the... 
ASC | pyroptosis | caspase-8 | cell death | inflammation | inflammasome | apoptosis | NLRC4 | NLRP1 | caspase-1 | Index Medicus
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 06/2018, Volume 501, Issue 2, pp. 351 - 357
Diabetic retinopathy (DR) is the common cause of diabetic vascular complications. The NOD-like receptor (NLR) family, pyrin domain containing 1 (NLRP1), also... 
ASC | Inflammation | NLRP1 | Diabetic retinopathy (DR) | VEGF | CELLS | ACTIVATION | CASPASE-1 | BIOCHEMISTRY & MOLECULAR BIOLOGY | BIOPHYSICS | GLUCOSE-METABOLISM | IL-1-BETA | EXPRESSION | Diabetic retinopathy | Endothelial growth factors | Interleukins | Blood sugar | Fructose | Index Medicus
Journal Article