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Nature (London), ISSN 1476-4687, 06/2014, Volume 512, Issue 7512, pp. 69 - 73
Journal Article
Journal of allergy and clinical immunology, ISSN 0091-6749, 09/2019, Volume 144, Issue 3, pp. 777 - 787.e9
Journal Article
American journal of physiology. Renal physiology, ISSN 1522-1466, 05/2015, Volume 308, Issue 9, pp. F993 - F1003
IL-1β-secreting nucleotide-binding oligomerization domain protein 3 (NLRP3) inflammasomes play a pivotal role in triggering innate immune responses in metabolic disease... 
Diabetic nephropathy | Uric acid | NLRP3 inflammasome | Macrophage | Physiology | Life Sciences & Biomedicine | Urology & Nephrology | Science & Technology | Inflammasomes - metabolism | Diabetic Nephropathies - etiology | NLR Family, Pyrin Domain-Containing 3 Protein | Coculture Techniques | Diabetes Mellitus, Type 2 - genetics | Humans | Male | NF-kappa B - metabolism | Hyperuricemia - metabolism | Diabetes Mellitus, Type 2 - metabolism | Diabetic Nephropathies - immunology | Hyperuricemia - immunology | Inflammation - metabolism | Transfection | RNA Interference | Time Factors | Interleukin-1beta - metabolism | Diabetes Mellitus, Type 2 - immunology | HMGB1 Protein - metabolism | Inflammation Mediators - metabolism | Diabetic Nephropathies - prevention & control | Hyperuricemia - complications | Diabetes Mellitus, Type 2 - complications | Macrophages - immunology | Disease Models, Animal | Cell Line | Kidney Tubules, Proximal - immunology | Uric Acid - metabolism | Signal Transduction | Diabetic Nephropathies - metabolism | Diabetic Nephropathies - genetics | Inflammation - immunology | Inflammation - etiology | Disease Progression | Inflammasomes - genetics | Hyperuricemia - drug therapy | Carrier Proteins - genetics | Rats, Inbred OLETF | Macrophages - metabolism | Animals | Carrier Proteins - metabolism | Chemokine CXCL12 - metabolism | Kidney Tubules, Proximal - metabolism | Gout Suppressants - pharmacology | Macrophages - drug effects | Kidney Tubules, Proximal - drug effects | Receptors, Cytoplasmic and Nuclear - metabolism | Type 2 diabetes | Cellular proteins | Kidneys | Immune response | Physiological aspects | Genetic aspects | Properties | Injuries | Cell culture | Diabetes | Kidney diseases | Rodents | Cells | Index Medicus
Journal Article
The international journal of biochemistry & cell biology, ISSN 1357-2725, 03/2017, Volume 84, pp. 22 - 34
... (NOD-like receptor family pyrin domain-containing3) inflammasome plays a central role in inflammatory response that is associated with diverse inflammatory diseases... 
TXNIP | Senescence | IL-1β | NLRP3 inflammasome | ROS | Biochemistry & Molecular Biology | Life Sciences & Biomedicine | Science & Technology | Cell Biology | Human Umbilical Vein Endothelial Cells | RNA, Small Interfering - genetics | Inflammasomes - metabolism | Reactive Oxygen Species - metabolism | Cytoskeletal Proteins - antagonists & inhibitors | Cytoskeletal Proteins - genetics | Humans | Cellular Senescence - drug effects | Male | Aorta - metabolism | RNA, Messenger - metabolism | NLR Family, Pyrin Domain-Containing 3 Protein - genetics | Aging - genetics | Interleukin-1beta - metabolism | Apoptosis Regulatory Proteins - genetics | Cytoskeletal Proteins - metabolism | Thioredoxins - metabolism | Bleomycin - toxicity | Endothelial Cells - metabolism | Models, Cardiovascular | NLR Family, Pyrin Domain-Containing 3 Protein - metabolism | Mice, Inbred C57BL | RNA, Messenger - genetics | Carrier Proteins - antagonists & inhibitors | NLR Family, Pyrin Domain-Containing 3 Protein - antagonists & inhibitors | Cellular Senescence - physiology | Aging - pathology | Apoptosis Regulatory Proteins - metabolism | Aorta - pathology | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Endothelial Cells - cytology | CARD Signaling Adaptor Proteins | Apoptosis Regulatory Proteins - antagonists & inhibitors | Mice | Aging - metabolism | Endothelial Cells - drug effects | Index Medicus
Journal Article
Bioorganic & medicinal chemistry letters, ISSN 0960-894X, 04/2020, Volume 30, Issue 7, pp. 127021 - 127021
[Display omitted] Aberrant activation of NLRP3 inflammasome is present in a subset of acute and chronic inflammatory diseases. The NLRP3 inflammasome has been... 
NLRP3 | Structure-activity relationship (SAR) | Thiazolidinones | Index Medicus
Journal Article