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nmnat (63) 63
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Pharmacology and Therapeutics, ISSN 0163-7258, 08/2019, Volume 200, pp. 27 - 41
Nicotinamide adenine dinucleotide (NAD ) is an essential biomolecule involved in many critical processes. Its role as both a driver of energy production and a... 
NAD | CD38 | PARP | NMNAT | SIRT | NAMPT | POLY(ADP-RIBOSE) POLYMERASE | NMN/NAMN ADENYLYLTRANSFERASE NMNAT | CELL-PROLIFERATION | NICOTINAMIDE ADENINE-DINUCLEOTIDE | NAMPT INHIBITOR | BREAST-CANCER | NAD(+) | DARATUMUMAB MONOTHERAPY | PHARMACOLOGY & PHARMACY | TUMOR-SUPPRESSIVE ACTIVITY | SALVAGE PATHWAY | HISTONE DEACETYLASE | Index Medicus
Journal Article
Brain Research, ISSN 0006-8993, 01/2020, Volume 1727, p. 146539
The programmed axon degeneration pathway has emerged as an important process contributing to the pathogenesis of several neurological diseases. The most... 
NAD | HSP | MPZ | Programmed axon degeneration | PMP22 | SARM1 | Therapy development | GARS | CMT | Peripheral neuropathy | NMNAT
Journal Article
ISSN 0960-9822, 2017
Axons require the axonal NAD-synthesizing enzyme NMNAT2 to survive. Injury or genetically induced depletion of NMNAT2 triggers axonal degeneration or defective... 
NAD | Wallerian degeneration | NMN deamidase | axon degeneration | WLD$^\text{s} | SARM1 | neurodegeneration | NMNAT2 | NMNAT | NMN
Journal Article
Neurobiology of Disease, ISSN 0969-9961, 2013, Volume 59, pp. 69 - 79
Abstract WldS mutation protects axons from degeneration in diverse experimental models of neurological disorders, suggesting that the mutation might act on a... 
Neurology | Energy deprivation | Axon injury | Calcium | Bioenergetics | WldS | ATP | NMNAT | Wld | calcium | energy deprivation | bioenergetics | axon injury
Journal Article
FRONTIERS IN CELLULAR NEUROSCIENCE, ISSN 1662-5102, 07/2016, Volume 10
Axon degeneration is a prominent feature of various neurodegenerative diseases, such as Parkinson's and Alzheimer's, and is often characterized by aberrant... 
vincristine | PROTECTION | mitochondria | neurodegeneration | SEGREGATION | NEUROSCIENCES | SENSORY NEURONS | fusion | ORGANIZATION | TRANSPORT | fission | DISEASE | MUTATIONS | Nmnat
Journal Article
CURRENT BIOLOGY, ISSN 0960-9822, 04/2012, Volume 22, Issue 7, pp. R221 - R223
Journal Article
MEMORIAS DO INSTITUTO OSWALDO CRUZ, ISSN 0074-0276, 2019, Volume 114, p. e180506
BACKGROUND Nicotinamide adenine dinucleotide (NAD) plays a central role in energy metabolism and integrates cellular metabolism with signalling and gene... 
Leishmania braziliensis | NAD | NETWORK | protein-protein interaction | Co-IP-MS/MS | IDENTIFICATION | NMNAT | PARASITOLOGY | TROPICAL MEDICINE
Journal Article