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Journal Article
Bioorganic & Medicinal Chemistry, ISSN 0968-0896, 05/2018, Volume 26, Issue 8, pp. 1653 - 1664
Both the inhibition of inflammatory flares and the treatment of hyperuricemia itself are included in the management of gout. Extending our efforts to... 
Xanthine oxidase | NOD-like receptor 3 | Anti-hyperuricemia | Gout | Toll-like receptor 4 | CHEMISTRY, MEDICINAL | HYPERURICEMIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | NLRP3 INFLAMMASOME | INHIBITOR | ARTHRITIS | Oxidases | Purines | Iron compounds | Sensors | Drug therapy
Journal Article
Journal of Lipid Research, ISSN 0022-2275, 01/2016, Volume 57, Issue 1, pp. 66 - 76
The Nod-like receptor 3 (NLRP3) inflammasome is an intracellular sensor that sets off the innate immune system in response to microbial-derived and endogenous... 
Obesity | Vitamin E | Diet and dietary lipids | Caspase 1 | Inflammation | A20 | Insulin signaling | NOD-like receptor protein 3 | VITAMIN-E | ACTIVATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | vitamin E | diet and dietary lipids | caspase 1 | DEATH | AUTOPHAGY | BETA | insulin signaling | inflammation | INSULIN-RESISTANCE | NF-KAPPA-B | obesity | T-CELLS | Chromans - immunology | NLR Family, Pyrin Domain-Containing 3 Protein | Obesity - immunology | Vitamin E - analogs & derivatives | Caspase 1 - metabolism | Male | NF-kappa B - metabolism | Adipose Tissue - immunology | Signal Transduction - immunology | Chromans - pharmacology | Inflammasomes - antagonists & inhibitors | AMP-Activated Protein Kinases - immunology | Inflammation - drug therapy | Diabetes Mellitus, Type 2 - immunology | Tumor Necrosis Factor-alpha - immunology | Vitamin E - immunology | Macrophages, Peritoneal - drug effects | Carrier Proteins - immunology | Carrier Proteins - antagonists & inhibitors | Insulin Resistance | Interleukin-1beta - immunology | Macrophages, Peritoneal - immunology | Inflammation - immunology | Mice, Knockout | Animals | Signal Transduction - drug effects | Inflammasomes - immunology | Lipopolysaccharides - pharmacology | Mice, Inbred NOD | Mice | Diabetes Mellitus, Type 2 - drug therapy | Adipose Tissue - drug effects | Vitamin E - pharmacology
Journal Article
Journal Article
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2016, Volume 139, Issue 5, pp. 1468 - 1477.e2
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2011, Volume 17, Issue 24, pp. 7645 - 7653
Journal Article
Nature Cell Biology, ISSN 1465-7392, 10/2015, Volume 17, Issue 10, pp. 1327 - 1338
Journal Article
Journal Article
BIOMED RESEARCH INTERNATIONAL, ISSN 2314-6133, 2018, Volume 2018, pp. 2817045 - 9
Journal Article
Nature Medicine, ISSN 1078-8956, 06/2015, Volume 21, Issue 6, pp. 619 - 627
Journal Article
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 01/2011, Volume 121, Issue 1, pp. 174 - 183
Journal Article