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Nature genetics, ISSN 1546-1718, 2018, Volume 50, Issue 11, pp. 1574 - 1583
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2009, Volume 119, Issue 3, pp. 565 - 572
.... Here we investigated whether mouse Th17 cells with specificity for an islet antigen can induce diabetes upon transfer into NOD/SCID recipient mice... 
ENCEPHALOMYELITIS | MEDICINE, RESEARCH & EXPERIMENTAL | INTERFERON-GAMMA RECEPTOR | NOD MICE | TGF-BETA | NONOBESE DIABETIC MICE | IN-VIVO | DIFFERENTIATION | T-HELPER TYPE-1 | EXPRESSION | CUTTING EDGE | Gene Expression - drug effects | Xenopus Proteins - genetics | Pancreas - cytology | Interleukin-17 - immunology | Th17 Cells - transplantation | Adoptive Transfer | Interferon-gamma - metabolism | Th1 Cells - immunology | Th1 Cells - transplantation | Th1 Cells - metabolism | Th17 Cells - drug effects | Th17 Cells - metabolism | Gene Expression - immunology | Receptors, Interleukin-12 - genetics | Th17 Cells - cytology | Diabetes Mellitus, Type 1 - immunology | Interferon-gamma - genetics | Macrophages - immunology | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Interleukin-12 - pharmacology | Basic Helix-Loop-Helix Transcription Factors - genetics | Antibodies, Monoclonal - pharmacology | Mice, Inbred C57BL | Receptors, Aryl Hydrocarbon - genetics | Interleukin-17 - genetics | Up-Regulation - genetics | Lymph Nodes - immunology | Lymph Nodes - cytology | Mice, SCID | Pancreas - immunology | Receptors, Interleukin - genetics | T-Box Domain Proteins - genetics | Down-Regulation - genetics | Cell Differentiation - immunology | Interleukin-17 - metabolism | Macrophages - metabolism | Animals | Cell Differentiation - drug effects | Diabetes Mellitus, Type 1 - blood | Interferon-gamma - immunology | Th17 Cells - immunology | Macrophages - drug effects | Mice, Inbred NOD | Mice | Th1 Cells - cytology | Blood Glucose - metabolism | Causes of | Physiological aspects | Development and progression | Research | Diabetes | Autoimmune diseases | T cells
Journal Article
Blood, ISSN 1528-0020, 2009, Volume 114, Issue 13, pp. 2667 - 2677
Journal Article
Journal Article
Journal Article
Journal Article
The Journal of clinical investigation, ISSN 0021-9738, 2007, Volume 117, Issue 12, pp. 3857 - 3867
.... Here, we demonstrate that B cell depletion in mice can prevent or delay diabetes, reverse diabetes after frank hyperglycemia, and lead to the development of cells that suppress disease... 
RHEUMATOID-ARTHRITIS | AUTOANTIBODIES | MEDICINE, RESEARCH & EXPERIMENTAL | T-REGULATORY-CELLS | NOD MOUSE | THERAPY | IMMUNOTHERAPY