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CELL, ISSN 0092-8674, 06/2019, Volume 177, Issue 7, pp. 1682 - 1699
Macroautophagy (herein referred to as autophagy) is an evolutionary ancient mechanism that culminates with the lysosomal degradation of superfluous or... 
NONCANONICAL AUTOPHAGY | UVRAG | BECLIN 1 | PROTEIN | TUMOR PROGRESSION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | C-VPS COMPLEX | DISTINCT ROLES | LC3-ASSOCIATED PHAGOCYTOSIS | CELL-DEATH | CELL BIOLOGY | Proteins | Medical colleges | Cell death
Journal Article
Nature Cell Biology, ISSN 1465-7392, 07/2015, Volume 17, Issue 7, pp. 893 - 906
LC3-associated phagocytosis (LAP) is a process wherein elements of autophagy conjugate LC3 to phagosomal membranes. We characterize the molecular requirements... 
NONCANONICAL AUTOPHAGY | REGULATE AUTOPHAGY | IMMUNITY | CROHN-DISEASE | INFLAMMATION | MICE | NADPH OXIDASE ACTIVATION | CELLULAR DEFENSE | BINDING | GENOME-WIDE ASSOCIATION | CELL BIOLOGY | Phagosomes - microbiology | Autophagy-Related Proteins | Phosphatidylinositol Phosphates - metabolism | Reactive Oxygen Species - metabolism | Membrane Glycoproteins - metabolism | Microtubule-Associated Proteins - genetics | Microtubule-Associated Proteins - metabolism | Vesicular Transport Proteins - metabolism | NADPH Oxidases - metabolism | Immunoblotting | Male | Green Fluorescent Proteins - genetics | Intracellular Signaling Peptides and Proteins - metabolism | Autophagy | RNA Interference | Tumor Suppressor Proteins - genetics | Aspergillus fumigatus - physiology | NADPH Oxidases - genetics | Female | Intracellular Signaling Peptides and Proteins - genetics | Macrophages - microbiology | Cell Line | Green Fluorescent Proteins - metabolism | Tumor Suppressor Proteins - metabolism | Mice, Inbred C57BL | Phagosomes - metabolism | Vesicular Transport Proteins - genetics | Class III Phosphatidylinositol 3-Kinases - metabolism | Mice, Transgenic | NADPH Oxidase 2 | Membrane Glycoproteins - genetics | Mice, Knockout | Host-Pathogen Interactions | Microscopy, Confocal | Macrophages - metabolism | Animals | Phagocytosis | Cellular proteins | Development and progression | Genetic aspects | Properties | Communicable diseases | Index Medicus
Journal Article
Philosophical Transactions of the Royal Society B: Biological Sciences, ISSN 0962-8436, 02/2019, Volume 374, Issue 1765, pp. 20180154 - 20180154
Adaptive strategies used by cells to scavenge and recycle essential nutrients are important for survival in nutrient-depleted environments such as cancer... 
entosis, phagocytosis | autophagy | macropinocytosis | phagocytosis | PROTEIN | KINASE | RECEPTOR | LC3-ASSOCIATED PHAGOCYTOSIS | CELL-DEATH | NONCANONICAL AUTOPHAGY | METABOLISM | GROWTH | BIOLOGY | entosis | LC3 | 33 | Review | 1001
Journal Article
Virulence, ISSN 2150-5594, 01/2019, Volume 10, Issue 1, pp. 352 - 362
Autophagy is a conserved and fundamental cellular process mainly to recycle or eliminate dysfunctional cellular organelles or proteins. As a response to... 
Intracellular bacteria | autophagy | autophagosome | bacterial effectors | autophagy pathways | MYCOBACTERIUM-TUBERCULOSIS | LISTERIA | INFECTIOUS DISEASES | MECHANISM | EARLY STEPS | MICROBIOLOGY | IMMUNOLOGY | SELECTIVE AUTOPHAGY | CONJUGATION SYSTEM | NONCANONICAL AUTOPHAGY | SHIGELLA | TARGETS | LC3 CONJUGATION
Journal Article
PLoS Biology, ISSN 1544-9173, 2019, Volume 17, Issue 1, pp. e2006926 - e2006926
Many viruses interface with the autophagy pathway, a highly conserved process for recycling cellular components. For three viral infections in which autophagy... 
REPLICATION | INHIBITION | BIOCHEMISTRY & MOLECULAR BIOLOGY | EARLY STEPS | MACHINERY | BIOLOGY | INFECTION | ULK1 COMPLEX | ATG9 | UNCONVENTIONAL SECRETION | PROTEINS | LC3 | Vector-borne diseases | Antiviral agents | CRISPR | RNA viruses | Starvation | Membranes | Dengue | Scavenging | Viral diseases | Viruses | Lipids | Infections | Genomes | Ribonucleic acid--RNA | Kinases | Autophagy | Proteins | Medicine | Immunology | Genetics | Curvature | Phagocytosis | Life Sciences | Cellular Biology | RNA | Ribonucleic acid
Journal Article
Autophagy, ISSN 1554-8627, 12/2011, Volume 7, Issue 12, pp. 1448 - 1461
Journal Article
Methods in molecular biology (Clifton, N.J.), ISSN 1064-3745, 2019, Volume 1880, pp. 295 - 303
Monitoring of ATG8 proteins by western blotting and immunofluorescence microscopy are the most common methods to monitor the autophagy pathway. However, it has... 
ATG8 | LAP | LC3 | Noncanonical autophagy | Phagocytosis | Index Medicus
Journal Article
Autophagy, ISSN 1554-8627, 04/2019, Volume 15, Issue 4, pp. 613 - 630
ULK1 (unc-51 like autophagy activating kinase 1) is a core component at multiple steps of canonical macroautophagy/autophagy. The activity of ULK1 is tightly... 
breast cancer | MAP1LC3B | Aggresomes | pimozide | noncanonical autophagy | deubiquitinating enzymes | CALPAIN | PHOSPHORYLATION | STABILITY | COMPLEXES | MECHANISMS | CHEMOTHERAPY | CELL BIOLOGY | BREAST-CANCER | INHIBITION | PATHWAY | DEUBIQUITINATION
Journal Article
PLoS Pathogens, ISSN 1553-7366, 2014, Volume 10, Issue 6, pp. e1004159 - e1004159
Autophagy has emerged as an important antimicrobial host defense mechanism that not only orchestrates the systemic immune response, but also functions in a... 
IMMUNITY | LC3 RECRUITMENT | HOST | MICROBIOLOGY | MAMMALIAN-CELLS | PLASMA-MEMBRANE | NONCANONICAL AUTOPHAGY | CONTAINING VACUOLE | VIROLOGY | EPITHELIAL-CELLS | GROWTH | INFECTION | PARASITOLOGY | Focal Adhesion Kinase 1 - genetics | Microtubule-Associated Proteins - genetics | TOR Serine-Threonine Kinases - metabolism | Microtubule-Associated Proteins - metabolism | Salmonella Infections - immunology | Salmonella Infections - metabolism | Autophagy | Macrophages, Peritoneal - cytology | Autophagy-Related Protein-1 Homolog | Salmonella typhimurium - metabolism | RNA Interference | Escherichia coli - pathogenicity | Escherichia coli - metabolism | Protein-Serine-Threonine Kinases - antagonists & inhibitors | Membrane Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Focal Adhesion Kinase 1 - metabolism | Protein-Serine-Threonine Kinases - metabolism | Specific Pathogen-Free Organisms | Salmonella typhimurium - immunology | Salmonella typhimurium - pathogenicity | Signal Transduction | Membrane Proteins - genetics | Bacterial Proteins - genetics | Cells, Cultured | Protein-Serine-Threonine Kinases - genetics | Escherichia coli - immunology | Macrophages, Peritoneal - immunology | Toll-Like Receptor 4 - genetics | Microbial Viability | Microtubule-Associated Proteins - antagonists & inhibitors | Toll-Like Receptor 4 - metabolism | Mice, Knockout | Animals | Macrophages, Peritoneal - microbiology | Autophagy-Related Protein 5 | Bacterial Proteins - metabolism | Salmonella Infections - microbiology | Enzyme Activation | Mutation | Macrophages, Peritoneal - metabolism | Phagocytosis | Care and treatment | Analysis | Macrophages | Health aspects | Protein kinases | Salmonella food poisoning | Risk factors | Index Medicus | Salmonella | Colleges & universities | Bacteria | Infections | Kinases | Adhesion
Journal Article
Journal Article
Autophagy, ISSN 1554-8627, 02/2019, Volume 15, Issue 2, pp. 228 - 241
Phagocytosis and macroautophagy/autophagy are 2 processes involved in lysosome-mediated clearance of extracellular and intracellular components, respectively.... 
Caenorhabditis elegans | phosphatidylserine | embryogenesis | cell death | VPS-39 | phagosome | LAP process | lysosome | Apoptosis | CLEARANCE | PHAGOCYTOSIS | LC3 RECRUITMENT | MACHINERY | CELL BIOLOGY | PROGRAMMED CELL-DEATH | NONCANONICAL AUTOPHAGY | GENES FUNCTION | PATHWAY | ENGULFMENT | SECRETION
Journal Article