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male (291) 291
brown adipose-tissue (287) 287
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BBA - Bioenergetics, ISSN 0005-2728, 07/2014, Volume 1837, Issue 7, pp. 1075 - 1082
The presence of two distinct types of adipose tissue, which have opposing functions, has been known for decades. White adipose tissue (WAT) is the main tissue... 
Rosiglitazone | Proton leak | Thermogenesis | Isoproterenol | Uncoupling protein 1 | Beige Adipocytes | BROWN-ADIPOSE-TISSUE | CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | DIET-INDUCED OBESITY | NONSHIVERING THERMOGENESIS | BIOPHYSICS | MITOCHONDRIAL UNCOUPLING PROTEIN | INSULIN-RESISTANCE | MICE | EXPRESSION | WHITE ADIPOCYTES | RNA | Gene expression | Analysis
Journal Article
European Journal of Clinical Nutrition, ISSN 0954-3007, 03/2017, Volume 71, Issue 3, pp. 345 - 352
Journal Article
Cell Metabolism, ISSN 1550-4131, 07/2014, Volume 20, Issue 1, pp. 41 - 53
Journal Article
Diabetes, ISSN 0012-1797, 06/2019, Volume 68, Issue 6, pp. 1178 - 1196
Carboxylesterase 3 (Ces3) is a hydrolase with a wide range of activities in liver and adipose tissue. In this study, we identified Ces3 as a major lipid... 
HORMONE-SENSITIVE LIPASE | ADIPOCYTES | LIPOLYSIS | FAT-CELLS | DECREASES BLOOD-LIPIDS | ENDOCRINOLOGY & METABOLISM | UCP1 | BROWN ADIPOSE-TISSUE | TRIACYLGLYCEROL | ADAPTIVE NONSHIVERING THERMOGENESIS | DROPLETS | Mitochondria | Adipose tissue | Thermogenesis | Hydrolase | Body temperature | Mass spectroscopy | Liquid chromatography | siRNA | Adipocytes | Isoproterenol | Carboxylesterase
Journal Article
Nature, ISSN 0028-0836, 08/2018, Volume 560, Issue 7716, pp. 102 - 106
Thermogenesis by brown and beige adipose tissue, which requires activation by external stimuli, can counter metabolic disease(1). Thermogenic respiration is... 
ENERGY-EXPENDITURE | NONSHIVERING THERMOGENESIS | METABOLISM | MULTIDISCIPLINARY SCIENCES | MITOCHONDRIA | LACTATE | FAT | UCP1 | DYSFUNCTION | BROWN-ADIPOCYTES | DEFICIENCY | Metabolomics | Reactive Oxygen Species - metabolism | Adipose Tissue, White - metabolism | Adipocytes - enzymology | Male | Adipocytes - drug effects | Thermogenesis - physiology | Adipose Tissue, White - cytology | Oxidation-Reduction - drug effects | Female | Uncoupling Protein 1 - metabolism | Adipose Tissue, Brown - enzymology | Obesity - metabolism | Adipose Tissue, Brown - cytology | Animals | Succinic Acid - pharmacology | Succinic Acid - metabolism | Adipocytes - metabolism | Obesity - prevention & control | Adipose Tissue, White - enzymology | Succinate Dehydrogenase - metabolism | Adipose Tissue, Brown - drug effects | Adipose Tissue, Brown - metabolism | Mice | Thermogenesis - drug effects | Adipose Tissue, White - drug effects | Adipose tissues | Physiological aspects | Control | Thermogenesis | Succinates | Protein kinase A | Tricarboxylic acid cycle | Reactive oxygen species | Succinate dehydrogenase | Dehydrogenases | Adipose tissue | Body fat | Activation | Adipocytes | Kinases | Dehydrogenase | Accumulation | Proteins | Signal transduction | Energy | Metabolites | Rodents | Oxidation | Adipose tissue (brown) | Oxygen | AMP | Cyclic AMP | Pharmacology | Metabolism | Lipolysis | Glucose tolerance | Signaling | Hypotheses | External stimuli | Respiration
Journal Article
Journal Article
Cell Metabolism, ISSN 1550-4131, 09/2017, Volume 26, Issue 3, pp. 454 - 455
Manipulating thermogenesis could increase energy expenditure and improve metabolism. Brown fat is a major site of nonshivering thermogenesis, but other... 
NONSHIVERING THERMOGENESIS | METABOLISM | ENDOCRINOLOGY & METABOLISM | HUMANS | BROWN ADIPOSE-TISSUE | MAMMALS | CELL BIOLOGY | Physiological aspects | Liver | Cells
Journal Article
NATURE MEDICINE, ISSN 1078-8956, 12/2017, Volume 23, Issue 12, pp. 1454 - 1454
Uncoupling protein 1 (UCP1) plays a central role in nonshivering thermogenesis in brown fat; however, its role in beige fat remains unclear. Here we report a... 
MEDICINE, RESEARCH & EXPERIMENTAL | MALIGNANT HYPERTHERMIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | BROWN ADIPOSE-TISSUE | ENDOPLASMIC-RETICULUM STRESS | RYANODINE RECEPTOR GENE | RELEASE CHANNEL | MASS-SPECTROMETRY | ADAPTIVE NONSHIVERING THERMOGENESIS | CELL BIOLOGY | ENERGY-EXPENDITURE | UNCOUPLING PROTEIN-1 | FK506-BINDING PROTEIN FKBP12.6 | Animals, Newborn | Thermogenesis - genetics | Uncoupling Protein 1 - genetics | Calcium - metabolism | Humans | Mice, Inbred C57BL | Cells, Cultured | Signal Transduction - genetics | Mice, Knockout | Sarcoplasmic Reticulum Calcium-Transporting ATPases - physiology | Animals | Swine | HEK293 Cells | Glucose - metabolism | Mice | Calcium Signaling - genetics | Adipose Tissue, Beige - metabolism | Homeostasis - genetics | Uncoupling Protein 1 - physiology | Physiological aspects | Homeostasis | Brown adipose tissue | Genetic aspects | Research | Calcium ions | Cycles | Calcium | Body weight | Ryanodine receptors | Pyruvic acid | Body weight loss | Glucose | Adipocytes | Ca2+-transporting ATPase | Calcium signalling | Receptors | Uncoupling protein 1 | Rodents | Calcium homeostasis | Metabolism | Glucose tolerance | Energy balance | Thermogenesis | Glycolysis | Adrenergic receptors | Endoplasmic reticulum | ATP | Receptors (physiology) | Adenosine triphosphatase | Calcium (reticular) | Calcium cycling | SERCA2 | Non-canonical thermogenesis | Obesity | Beige fat | UCP1 | Diabetes
Journal Article
Journal Article