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FEBS JOURNAL, ISSN 1742-464X, 03/2016, Volume 283, Issue 6, pp. 1168 - 1179
Tissue-nonspecific alkaline phosphatase (TNSALP) is a membrane glycoprotein with a proposed role in bone mineralization. Indeed, mutations in TNSALP have been... 
enzyme activity | BIOCHEMISTRY & MOLECULAR BIOLOGY | dimerization | tissue-nonspecific alkaline phosphatase | hypophosphatasia | N-glycan
Journal Article
Bioorganic Chemistry, ISSN 0045-2068, 10/2019, Volume 91, p. 103137
Binding interaction of potent compound in -IAP (left) and -TNAP (right). Design, synthesis and characterization of new trinary... 
Design | Synthesis | Azomethine | Tissue-nonspecific alkaline phosphatase | Human intestinal alkaline phosphatase | Anticancer | Coumarin | Thiazole | TARGET | BIOCHEMISTRY & MOLECULAR BIOLOGY | QUANTITATION | CHEMISTRY, ORGANIC | GROWTH
Journal Article
The FEBS Journal, ISSN 1742-464X, 03/2016, Volume 283, Issue 6, pp. 1168 - 1179
Journal Article
Molecular and Cellular Biochemistry, ISSN 0300-8177, 8/2008, Volume 315, Issue 1, pp. 51 - 60
Tissue-nonspecific alkaline phosphatase (TNAP) plays a key role in mineralization by degrading inorganic pyrophosphate and providing free inorganic phosphate.... 
Life Sciences | Biochemistry, general | Mineralization | Levamisole | Oncology | Medical Biochemistry | Tissue-nonspecific alkaline phosphatase | Cardiology | PHEX | Phosphonoformic acid | MEMBRANE GLYCOPROTEIN-1 | MISSENSE | phosphonoformic acid | HYPOPHOSPHATASIA | CELL BIOLOGY | mineralization | OSTEOPONTIN | levamisole | INORGANIC PYROPHOSPHATE | tissue-nonspecific alkaline phosphatase | GENE-EXPRESSION | BONE | MUTATIONS | BETA-GLYCEROPHOSPHATE | Organ Specificity - drug effects | Gene Expression Regulation, Enzymologic - drug effects | Luciferases - metabolism | Foscarnet - pharmacology | Humans | Alkaline Phosphatase - metabolism | Glycoproteins - metabolism | Pyrophosphatases - genetics | RNA Stability - drug effects | Phosphoproteins - metabolism | RNA, Messenger - metabolism | PHEX Phosphate Regulating Neutral Endopeptidase - genetics | Glycerol - pharmacology | Phosphates - pharmacology | Extracellular Matrix Proteins - metabolism | Glycoproteins - genetics | Cell Line | PHEX Phosphate Regulating Neutral Endopeptidase - metabolism | Alkaline Phosphatase - genetics | Phosphoric Diester Hydrolases - metabolism | Calcification, Physiologic - drug effects | Osteoblasts - enzymology | Extracellular Matrix Proteins - genetics | Osteoblasts - drug effects | RNA, Messenger - genetics | Enzyme Inhibitors - pharmacology | Phosphoric Diester Hydrolases - genetics | Phosphoproteins - genetics | Enzyme Activation - drug effects | Levamisole - pharmacology | Pyrophosphatases - metabolism | Cell Proliferation - drug effects | Phosphates | Enzymes | Biochemistry | Cellular biology
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 08/2010, Volume 285, Issue 34, pp. 26066 - 26073
In previous studies, we observed that mice knocked out for the serotonin-2B receptor (5-HT2BR) show defects in bone homeostasis. The present work focuses on... 
ACTIVATION | INHIBITION | PROTEIN | INFANTILE HYPOPHOSPHATASIA | BONE-FORMATION | 5-HYDROXYTRYPTAMINE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MINERALIZATION | DIFFERENTIATION | CELL | EXPRESSION | Signal Transduction | Serotonin | G Proteins | Eicosanoids | Stem | Organ Systems | Tissue-Nonspecific Alkaline Phosphatase | Tissue | Receptors | Neurotransmitters | Coupled Receptors (GPCR) | Bone | Cell
Journal Article
American Journal of Physiology - Renal Physiology, ISSN 0363-6127, 09/2014, Volume 307, Issue 6, pp. F680 - F685
CD73 metabolizes extracellular 5'-AMP to adenosine; yet recent experiments in brain tissue suggest that CD73 is not required for the metabolism of 5'-AMP to... 
5'-AMP |