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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, ISSN 0002-7863, 01/2020, Volume 142, Issue 2, pp. 792 - 800
The Pictet-Spengler reaction is a valuable route to 1,2,3,4-tetrahydro-beta-carboline (THBC) and isoquinoline scaffolds found in many important... 
TETRAHYDRO-BETA-CARBOLINES | BENZYLISOQUINOLINE ALKALOID BIOSYNTHESIS | CAMPTOTHECIN | RAUVOLFIA | PURIFICATION | KEY ENZYME | INTERMEDIATE | NORCOCLAURINE SYNTHASE | AUXILIARY | CHEMISTRY, MULTIDISCIPLINARY | CYCLIZATION
Journal Article
ACS CATALYSIS, ISSN 2155-5435, 10/2019, Volume 9, Issue 10, pp. 9640 - 9649
Norcoclaurine synthase (NCS) catalyzes a stereoselective Pictet-Spengler reaction to give the key intermediate, (S)-norcoclaurine in benzylisoquinoline... 
norcoclaurine synthase | ENZYME | TETRAHYDROISOQUINOLINES | BENZYLISOQUINOLINE ALKALOID BIOSYNTHESIS | ALKYLATION | tetrahydroisoquinoline | kinetic resolution | DOPAMINE-1ST MECHANISM | CHEMISTRY, PHYSICAL | Pictet-Spengler | biocatalysis
Journal Article
BMC Plant Biology, ISSN 1471-2229, 12/2018, Volume 18, Issue 1, pp. 338 - 12
Journal Article
NATURE COMMUNICATIONS, ISSN 2041-1723, 04/2017, Volume 8, Issue 1, p. 14883
The Pictet-Spengler reaction (PSR) involves the condensation and ring closure between a beta-arylethylamine and a carbonyl compound. The combination of... 
YEAST | STRICTOSIDINE SYNTHASE | ALKALOID BIOSYNTHESIS | ASYMMETRIC-SYNTHESIS | SPIROBENZYLISOQUINOLINE | ERYTHRINA ALKALOIDS | MECHANISM | MULTIDISCIPLINARY SCIENCES | 1,2,3,4-TETRAHYDROISOQUINOLINES | NORCOCLAURINE SYNTHASE | SKELETON
Journal Article
Chemical Communications, ISSN 1359-7345, 2018, Volume 54, Issue 11, pp. 1323 - 1326
Chemoenzymatic reaction cascades can provide access to chiral compounds from low-cost starting materials in one pot. Here we describe one-pot asymmetric routes... 
YEAST | ENZYME | PICTET-SPENGLER REACTION | BIOSYNTHESIS | DOPAMINE-1ST MECHANISM | ENABLES | NORCOCLAURINE SYNTHASE | CHEMISTRY, MULTIDISCIPLINARY | ALKALOIDS
Journal Article
Advanced Synthesis & Catalysis, ISSN 1615-4150, 11/2012, Volume 354, Issue 16, pp. 2997 - 3008
The versatility and potential of a norcoclaurine synthase (NCS) from Coptis japonica NCS2 has been investigated, together with the development and application... 
tetrahydroisoquinolines | norcoclaurine synthase | biotransformations | Pictet–Spengler reaction | alkaloids | MECHANISM | CHEMISTRY, ORGANIC | STRICTOSIDINE SYNTHASE | ENZYME | BENZYLISOQUINOLINE ALKALOID BIOSYNTHESIS | ISOQUINOLINE | PURIFICATION | 1ST COMMITTED STEP | PRIMARY AMINES | CHEMISTRY, APPLIED | Pictet-Spengler reaction | EXPRESSION | Aldehydes
Journal Article
Chemical Communications : Chem Comm, ISSN 1359-7345, 01/2018, Volume 54, Issue 11, pp. 1323 - 1326
Chemoenzymatic reaction cascades can provide access to chiral compounds from low-cost starting materials in one pot. Here we describe one-pot asymmetric routes... 
Chemical synthesis | Alkaloids | Cascades
Journal Article
ChemCatChem, ISSN 1867-3880, 11/2018, Volume 10, Issue 21, pp. 4783 - 4804
Journal Article
Planta, ISSN 0032-0935, 10/2001, Volume 213, Issue 6, pp. 898 - 906
Journal Article