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index medicus (162) 162
notochordal cells (143) 143
animals (122) 122
humans (122) 122
nucleus pulposus (105) 105
orthopedics (81) 81
degeneration (79) 79
intervertebral disc (76) 76
female (65) 65
male (65) 65
clinical neurology (63) 63
nucleus pulposus cells (61) 61
intervertebral disc degeneration (59) 59
cell biology (57) 57
extracellular-matrix (55) 55
in-vitro (53) 53
chordoma (51) 51
expression (50) 50
intervertebral disc - metabolism (43) 43
intervertebral disc - cytology (42) 42
adult (41) 41
middle aged (40) 40
surgery (39) 39
low-back-pain (37) 37
phenotype (37) 37
gene-expression (36) 36
notochordal cell (36) 36
intervertebral disc - pathology (35) 35
intervertebral disc degeneration - pathology (35) 35
pathology (35) 35
differentiation (33) 33
apoptosis (31) 31
cells, cultured (31) 31
gene expression (31) 31
notochord (31) 31
aged (30) 30
chordoma - pathology (30) 30
mesenchymal stem-cells (30) 30
physiological aspects (30) 30
collagen (29) 29
annulus fibrosus (28) 28
notochord - cytology (28) 28
spine (28) 28
benign notochordal cell tumor (27) 27
intervertebral discs (27) 27
magnetic resonance imaging (27) 27
regeneration (27) 27
notochordal cell tumors (26) 26
rats (26) 26
analysis (25) 25
developmental biology (23) 23
medicine & public health (23) 23
notochord - metabolism (23) 23
article (22) 22
classic chordomas (22) 22
intervertebral disc - physiology (22) 22
intervertebral disc degeneration - metabolism (22) 22
notochord - pathology (22) 22
cell & tissue engineering (21) 21
immunohistochemistry (21) 21
disease models, animal (20) 20
stem cells (20) 20
chondrocytes (19) 19
extracellular matrix (19) 19
benign (18) 18
rabbits (18) 18
research (17) 17
research article (17) 17
spinal neoplasms - pathology (17) 17
adolescent (16) 16
aging (16) 16
anatomy & morphology (16) 16
diagnosis, differential (16) 16
musculoskeletal diseases (16) 16
nuclei (16) 16
oncology (16) 16
swine (16) 16
tissue engineering (16) 16
biochemistry & molecular biology (15) 15
brachyury (15) 15
chondrocytes - cytology (15) 15
intervertebral disc degeneration - therapy (15) 15
medicine, research & experimental (15) 15
notochordal plate (15) 15
care and treatment (14) 14
chordoma - diagnosis (14) 14
extracellular matrix - metabolism (14) 14
matrix (14) 14
mice (14) 14
notochord - embryology (14) 14
progenitor cells (14) 14
radiology, nuclear medicine & medical imaging (14) 14
rest (14) 14
age (13) 13
articular-cartilage (13) 13
cell differentiation (13) 13
genetic aspects (13) 13
notochordal rest (13) 13
stromal cells (13) 13
transplantation (13) 13
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Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 09/2013, Volume 8, Issue 9, p. e75548
Journal Article
Tissue engineering. Part A, ISSN 1937-3341, 2009, Volume 15, Issue 9, pp. 2581 - 2595
This study aimed to evaluate whether rat mesenchymal stem cells (rMSCs) could be differentiated in vitro into disc-like cells by coculturing with... 
NUCLEUS PULPOSUS | FUSION | NOTOCHORDAL CELL | CELL & TISSUE ENGINEERING | CELL BIOLOGY | CHONDROCYTE-SPECIFIC ENHANCER | IN-VITRO | THERAPY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | REGIONAL-VARIATIONS | EXTRACELLULAR-MATRIX | SOX9 | STROMAL CELLS | Bone Matrix - metabolism | SOX9 Transcription Factor - metabolism | Intervertebral Disc - cytology | Bone Marrow Cells - cytology | Coculture Techniques | Multipotent Stem Cells - metabolism | Gene Expression Regulation | Mesenchymal Stromal Cells - metabolism | Proteoglycans - biosynthesis | Rats | Gene Expression Profiling | Aggrecans - metabolism | Rats, Sprague-Dawley | Collagen Type II - metabolism | Mesenchymal Stromal Cells - cytology | Animals | Mesenchymal Stromal Cells - ultrastructure | Multipotent Stem Cells - cytology | Cell Shape | Karyotyping | Cell Differentiation | Collagen - biosynthesis | Chondrocytes - metabolism | Cell Movement | Animal experimentation | Degeneration (Pathology) | Usage | Collagen | Stem cells | Physiological aspects | Genetic aspects | Research | Health aspects | Risk factors | Methods | Cell culture | Tissue engineering | Spine | Rodents | Collagen Type II/metabolism | Chondrocytes/metabolism | Kirurgi | Bone Matrix/metabolism | Mesenchymal Stem Cells/cytology/metabolism/ultrastructure | Sprague-Dawley | SOX9 Transcription Factor/metabolism | Collagen/biosynthesis | Multipotent Stem Cells/cytology/metabolism | Surgery | Bone Marrow Cells/cytology | Proteoglycans/biosynthesis | Aggrecans/metabolism | Intervertebral Disk/cytology
Journal Article
Journal Article
American Journal of Surgical Pathology, ISSN 0147-5185, 01/2017, Volume 41, Issue 1, pp. 39 - 48
Journal Article
Tissue Engineering - Part A, ISSN 1937-3341, 08/2017, Volume 23, Issue 15-16, pp. 837 - 846
Recent studies suggested that notochordal cells (NCs) and NC-conditioned medium (NCCM) can stimulate cell viability and matrix production of nucleus pulposus... 
Coculture | Cell therapy | Notochordal cell-rich nucleus pulposus | Intervertebral disc | Nucleus pulposus cells | intervertebral disc | nucleus pulposus cells | ANNULUS FIBROSUS CELLS | CULTURE | MESENCHYMAL STEM-CELLS | CELL & TISSUE ENGINEERING | CELL BIOLOGY | IN-VITRO | coculture | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | cell therapy | notochordal cell-rich nucleus pulposus | INTERVERTEBRAL DISC REGENERATION | MATRIX HOMEOSTASIS | SENESCENCE | STROMAL CELLS | CONDITIONED MEDIUM | INFLAMMATORY MEDIATORS | Notochord - cytology | Rabbits | Cell Proliferation | Cell Survival | Glycosaminoglycans - metabolism | Cell Count | Humans | Middle Aged | Cells, Cultured | Gene Expression Regulation | Extracellular Matrix - metabolism | Male | Nucleus Pulposus - cytology | DNA - metabolism | Coculture Techniques - methods | Intervertebral Disc Degeneration - pathology | Phenotype | Animals | Cellular Senescence | Female | Cell proliferation | Cell culture | Senescence | Collagen (type II) | Arthritis | Nucleus pulposus | Intervertebral discs | Bone surgery | Nuclei | Engineering | Cell cycle | Aging | Extracellular matrix | Physiology | Conditioning | Deoxyribonucleic acid--DNA | Explants | Incubation | Tissue engineering | Digestive system | Digestion | Gene expression | Studies | Regeneration | Orthopedics | Stem cells | Nuclei (cytology) | Laboratory animals | Viability | In vitro methods and tests
Journal Article
by Cai, F and Zhu, L and Wang, F and Shi, R and Xie, XH and Hong, X and Wang, XH and Wu, XT
DNA AND CELL BIOLOGY, ISSN 1044-5498, 02/2017, Volume 36, Issue 2, pp. 143 - 158
Inflammation is thought to have a major role in the pathogenesis of disc degeneration. Studies have shown that nucleus pulposus cells (NPCs) respond to one or... 
intervertebral disc | ACTIVATED PROTEIN-KINASE | TGF-BETA | LOW-BACK-PAIN | TGF-beta 1 | HUMAN INTERVERTEBRAL DISC | SPINE DEGENERATION | paracrine | BIOCHEMISTRY & MOLECULAR BIOLOGY | NECROSIS-FACTOR-ALPHA | MAPK | CYTOKINE EXPRESSION | MESENCHYMAL STEM-CELLS | CELL BIOLOGY | NF-kappa B | NOTOCHORDAL CELLS | GENETICS & HEREDITY | TNF-ALPHA
Journal Article
Materials Science & Engineering C, ISSN 0928-4931, 06/2019, Volume 99, pp. 1213 - 1225