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Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 07/2014, Volume 82, pp. 56 - 67
Journal Article
Journal Article
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 02/2018, Volume 116, pp. 141 - 148
NAD(P)H:quinone oxidoreductase 1 (NQO1) is a flavoenzyme upregulated in response to oxidative stress and in some cancers. Its upregulation by compounds has... 
High throughput screening | NQO1 | Analytical methods | Natural products | Cancer | HUMAN COLON | VISUALIZATION | MITOMYCIN-C | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRIMETHYL LOCK | DETERMINANT | BIOACTIVATION | HUMAN CANCER-CELLS | DT-DIAPHORASE | ENDOCRINOLOGY & METABOLISM | MECHANISM-BASED INHIBITOR | CYTOTOXICITY | Index Medicus
Journal Article
by Li, LR and Dong, H and Song, EQ and Xu, XY and Liu, LC and Song, Y
CHEMICO-BIOLOGICAL INTERACTIONS, ISSN 0009-2797, 02/2014, Volume 209, pp. 56 - 67
Nrf2/ARE pathway plays an important role in adapt to oxidative stress caused by pro-oxidants and electrophiles through up-regulating phase II detoxifying... 
MOLECULAR-MECHANISM | NQO1 | OXIDATIVE STRESS | ARYL-HYDROCARBON | BIOCHEMISTRY & MOLECULAR BIOLOGY | HO-1 | MAPK | DRUG-METABOLIZING-ENZYMES | PCB | TRANSCRIPTION FACTOR NRF2 | ANTIOXIDANT RESPONSE ELEMENT | ROS | Keap1 | PHARMACOLOGY & PHARMACY | TOXICOLOGY | VASCULAR ENDOTHELIAL-CELLS | HEME OXYGENASE-1 | SUBSTRATE ADAPTER PROTEIN | INDUCIBLE EXPRESSION
Journal Article
by Kwon, N and Cho, MK and Park, SJ and Kim, D and Nam, SJ and Cui, L and Kim, HM and Yoon, J
CHEMICAL COMMUNICATIONS, ISSN 1359-7345, 01/2017, Volume 53, Issue 3, pp. 525 - 528
A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ,... 
VISUALIZATION | ACTIVATION | TEMPERATURE | DT-DIAPHORASE | NITROREDUCTASE | SUBSTRATE | MITOCHONDRIA | HUMAN CANCER-CELLS | SELECTIVE DETECTION | CHEMISTRY, MULTIDISCIPLINARY | OVEREXPRESS NQO1 | Quinones | Propionic acid | Imaging | Fluorescence | Displays | Chemical compounds | Tumors | Cancer
Journal Article
Chemical Communications, ISSN 1359-7345, 2017, Volume 53, Issue 3, pp. 525 - 528
A new quinone propionic acid locked TP fluorophore which can be used for human NAD(P)H:quinone oxidoreductase (hNQO1) detection was developed. The probe, TPQ,... 
Fluorescent Dyes - chemistry | Optical Imaging | Propionates - chemistry | Quinones - chemistry | Humans | Cell Line, Tumor | NAD(P)H Dehydrogenase (Quinone) - analysis | Microscopy, Fluorescence, Multiphoton
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 07/2017, Volume 174, Issue 14, pp. 2161 - 2173
Azoreductases are flavoenzymes that have been characterized in a range of prokaryotes and eukaryotes. Bacterial azoreductases are associated with the... 
NITROAROMATIC COMPOUNDS | NAD(P)H-QUINONE OXIDOREDUCTASE-1 | FMN-DEPENDENT AZOREDUCTASE | DT-DIAPHORASE | CRYSTAL-STRUCTURE | ESCHERICHIA-COLI | PROSTATE-CANCER | PHARMACOLOGY & PHARMACY | OXIDOREDUCTASE 1 NQO1 | 5-AMINOSALICYLIC ACID | BETA-LAPACHONE | Neoplasms - metabolism | Bacteria - metabolism | Quinones - chemistry | Humans | Bacteria - drug effects | Anti-Bacterial Agents - metabolism | Antineoplastic Agents - chemistry | Nitrofurans - pharmacology | Neoplasms - drug therapy | Antineoplastic Agents - metabolism | Azo Compounds - chemistry | Anti-Bacterial Agents - chemistry | Nitrofurans - metabolism | Anti-Bacterial Agents - pharmacology | Antineoplastic Agents - pharmacology | Azo Compounds - metabolism | NADH, NADPH Oxidoreductases - metabolism | Azo Compounds - pharmacology | Quinones - pharmacology | Nitrofurans - chemistry | Quinones - metabolism | Oxidases | Drugs | Drug resistance in microorganisms | Chemotherapy | Gastrointestinal diseases | Quinone | Physiological aspects | Azo compounds | Single nucleotide polymorphisms | Chromosomes | Cancer | Inflammatory bowel diseases | Prokaryotes | Medical treatment | Single-nucleotide polymorphism | Metabolism | Drug development | Substrates | NAD | Quinones | Reduction | Eukaryotes | Antibiotics | Intestine | Medical prognosis | Antibiotic resistance | Azoreductase | Azo | Drug metabolism | Bacteria | Colon | Themed Section | Review
Journal Article
Free Radical Biology and Medicine, ISSN 0891-5849, 2007, Volume 42, Issue 11, pp. 1690 - 1703
Journal Article