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Neuropharmacology, ISSN 0028-3908, 12/2019, Volume 160, p. 107755
Poly(ADP-ribose) polymerase-1 (PARP1) is a ubiquitous nuclear enzyme that regulates DNA repair and genomic stability. In oxidative genotoxic conditions, PARP1... 
NAD | TFAM | PARP | PGC-1α | SIRT1 | NRF-1
Journal Article
Molecular and Cellular Endocrinology, ISSN 0303-7207, 01/2020, Volume 500, p. 110631
The reduction in muscle mass and strength with age, sarcopenia, is a prevalent condition among the elderly, linked to skeletal muscle dysfunction and cell... 
Testosterone | Tfam | Mitochondrial biogenesis | Mitochondrial genes | NRF-1
Journal Article
Cancer Research, ISSN 0008-5472, 2019, Volume 79, Issue 7, pp. 1353 - 1368
AlthoughAfrican-American (AA) patients with prostate cancer tend to develop greater therapeutic resistance and faster prostate cancer recurrence compared with... 
ACTIVATION | BIOGENESIS | METABOLISM | ONCOLOGY | PHOSPHORYLATION | MYC | NRF-1 | DEPENDENT PROTEIN-KINASE | KAPPA-B | FISSION | DRP1
Journal Article
Cell Metabolism, ISSN 1550-4131, 05/2017, Volume 25, Issue 5, pp. 1176 - 1185.e5
The objective of this study was to evaluate the specific mechanism(s) by which PPARβ regulates mitochondrial content in skeletal muscle. We discovered that... 
PGC-1α | PPARβ | mitochondria | muscle | NRF-1 | RAT SKELETAL-MUSCLE | TRANSCRIPTIONAL COACTIVATOR PGC-1-ALPHA | ENDURANCE EXERCISE | PROTEIN-KINASE | ENDOCRINOLOGY & METABOLISM | FIBER-TYPE | GLUCOSE-TRANSPORT | ACTIVATED RECEPTOR-DELTA | ENERGY-METABOLISM | MAMMALIAN-CELLS | GAMMA COACTIVATOR-1 | CELL BIOLOGY
Journal Article
Journal of Clinical Biochemistry and Nutrition, ISSN 0912-0009, 2015, Volume 56, Issue 2, pp. 91 - 97
Nuclear factor erythroid-derived 2-related factor 2 (Nrf2) was originally identified as a positive regulator of drug detoxifying enzyme gene expression during... 
heme oxygenase-1 | Nrf2 | p62 | mitochondria | NRF-1 | Mitochondria | P62 | Heme oxygenase-1 | OXIDATIVE STRESS | ACTIVATION | PROTEIN | FRATAXIN DEFICIENCY LEADS | DJ-1 | NUTRITION & DIETETICS | TRANSCRIPTION FACTOR NRF2 | BIOGENESIS | MICE | EXPRESSION | Review
Journal Article
Comparative Biochemistry and Physiology, Part A, ISSN 1095-6433, 08/2019, Volume 234, pp. 60 - 67
The peroxisome proliferator activated receptor γ coactivator-1 (PGC-1) family is composed of three coactivators whose role in regulating mammalian... 
Mitochondria | PPAR | Citrate synthase | ERRα | NRF-1 | Lipid oxidation | PHYSIOLOGY | MITOCHONDRIAL BIOGENESIS | ERR-ALPHA | BIOCHEMISTRY & MOLECULAR BIOLOGY | PROLIFERATOR-ACTIVATED RECEPTOR | COORDINATION | INDUCIBLE COACTIVATOR | THERMOGENESIS | SKELETAL-MUSCLE | ZOOLOGY | ERR alpha | GENE-EXPRESSION | TRANSCRIPTIONAL CONTROL | ENERGY-METABOLISM
Journal Article
Journal of the American College of Nutrition, ISSN 0731-5724, 11/2018, Volume 37, Issue 8, pp. 738 - 748
There is clear evidence that endurance exercise training elicits intramuscular adaptations that can lead to elevations in mitochondrial biogenesis, oxidative... 
PQQ | CREB | mtDNA | mitochondria | NRF-1 | TFAM | exercise | PGC-1α | skeletal muscle | VITAMIN-C | OXIDATIVE STRESS | SIGNALING PATHWAYS | ACTIVATED PROTEIN-KINASE | PHYSIOLOGICAL IMPORTANCE | PGC-1 alpha | NUTRITION & DIETETICS | REDUCED FORM | ANTIOXIDANT | TRANSCRIPTIONAL CONTROL | O-QUINONE
Journal Article
Chinese Journal of Cancer Prevention and Treatment, ISSN 1673-5269, 07/2011, Volume 18, Issue 14, pp. 1092 - 1095
Journal Article
British Journal of Surgery, ISSN 0007-1323, 01/2019, Volume 106, Issue 1, pp. 120 - 131
Journal Article
MOLECULAR AND CELLULAR BIOLOGY, ISSN 0270-7306, 06/2001, Volume 21, Issue 11, pp. 3738 - 3749
he thermogenic peroxisome proliferator-activated receptor gamma (PPAR-gamma) coactivator 1 (PGC-1) has previously been shown to activate mitochondrial... 
CYTOCHROME-C | ACTIVATION | ATP SYNTHASE | MITOCHONDRIAL BIOGENESIS | DNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | NRF-1 | GENES | EXPRESSION | BINDING | RECEPTOR-ALPHA | CELL BIOLOGY
Journal Article
NATURE, ISSN 0028-0836, 08/2019, Volume 572, Issue 7770, pp. 474 - 474
Journal Article
Journal Article