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Biochemical and Biophysical Research Communications, ISSN 0006-291X, 10/2019
Journal Article
Acta Hepatologica Japonica, ISSN 0451-4203, 2018, Volume 59, Issue 4, pp. 230 - 233
Journal Article
12/2008
Sequence variation among different hepatitis C virus (HCV) isolates has adaptive significance and reflects the modes and intensities of selection mechanisms... 
hepatitis C virus - 5' UTR - NS5A - therapeutic
Web Resource
Virology, ISSN 0042-6822, 2012, Volume 432, Issue 2, pp. 376 - 388
Abstract In this report, classical swine fever virus (CSFV) NS5A inhibit viral RNA replication when its concentration reached and surpassed the level of NS5B.... 
Infectious Disease | NS5A–NS5B interaction | Classical swine fever virus | Viral replication | NS5A | NS5B | DIARRHEA VIRUS | DOMAIN | NS5A-NS5B interaction | NONSTRUCTURAL PROTEIN 5A | DEPENDENT TRANSLATION | IDENTIFICATION | SITE-MEDIATED TRANSLATION | REGION | VIROLOGY | POLYMERASES | HEPATITIS-C | FAMILY FLAVIVIRIDAE
Journal Article
Journal of virology, ISSN 0022-538X, 01/2019, Volume 93, Issue 1
Type I interferon (IFN) inhibits viruses by inducing the expression of antiviral proteins. The IFN-induced myxovirus resistance B (MxB) protein has been... 
hepatitis C virus | Flaviviridae | NS5A | MxB | CypA | HOST | AMINO-TERMINAL DOMAIN | VIROLOGY | NS5A PROTEIN | RESISTANCE | ANTIVIRAL ACTIVITY | INFLUENZA-VIRUS | OLIGOMERIZATION | EXPRESSION | GTPASE | CYCLOPHILIN
Journal Article
Journal of Hepatology, ISSN 0168-8278, 2013, Volume 60, Issue 3, pp. 490 - 499
Journal Article
Clinical Gastroenterology and Hepatology, ISSN 1542-3565, 03/2018, Volume 16, Issue 3, pp. 417 - 426
Hepatitis C virus (HCV) has high genotypic diversity and global distribution. Agents that are effective against all major HCV genotypes, with shorter treatment... 
Direct-acting Antiviral | Short-duration | DAA | Pangenotypic | GLECAPREVIR | VELPATASVIR | PIBRENTASVIR | NS5A | SOFOSBUVIR | ADULTS | HCV | GASTROENTEROLOGY & HEPATOLOGY
Journal Article
Bioorganic and Medicinal Chemistry Letters, ISSN 0960-894X, 02/2013, Volume 23, Issue 3, pp. 779 - 784
In a recent disclosure, we described the discovery of dimeric, prolinamide-based NS5A replication complex inhibitors exhibiting excellent potency towards an... 
Daclatasvir | NS5A inhibitors | Stilbene replacement | Antivirals | HCV
Journal Article
Journal of Virology, ISSN 0022-538X, 10/2018, Volume 92, Issue 20
The hepatitis C virus (HCV) protein NS5A is a phosphorylated protein with crucial roles in viral replication and assembly. NS5A was thought to undergo... 
S232 | Phosphorylation | HCV | Antibody | NS5A | DOMAIN | antibody | RNA REPLICATION | NONHEPATIC CELLS | NS3 | VIROLOGY | SUBSTRATE | NS4A | KINASE-I-ALPHA | NS5A HYPERPHOSPHORYLATION | INFECTION | phosphorylation | INSIGHTS
Journal Article
Journal of Virology, ISSN 0022-538X, 06/2018, Volume 92, Issue 11
RAD51-associated protein 1 (RAD51AP1) is a member of the multiprotein complexes postulated to carry out RAD51-mediated homologous recombination and DNA repair... 
RAD51AP1 | RAD51 | NS5A | DNA repair | Homologous recombination | RAD51 RECOMBINASE | COMPLEX | SENSITIVITY | BINDING PROTEIN | GENOMIC STABILITY | VIROLOGY | homologous recombination | NS5A PROTEIN | INTERACTS | GENE-EXPRESSION | CELL
Journal Article
Journal of General Virology, ISSN 0022-1317, 01/2018, Volume 99, Issue 1, pp. 44 - 61
Proprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease actively involved in regulating lipid homeostasis. Although PCSK9 has been shown to... 
HCV replication | PCSK9 | NS5A dimerization | Protein interaction | NS5A | RNA binding | protein interaction | PROTEIN | RNA TRANSLATION | CRYSTAL-STRUCTURE | HYPERCHOLESTEROLEMIA | NATURAL-HISTORY | IN-VITRO | VIROLOGY | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | DIRECT-ACTING ANTIVIRALS | HCV | DENSITY-LIPOPROTEIN RECEPTOR
Journal Article
Journal Article
Virology, ISSN 0042-6822, 01/2018, Volume 514, pp. 18 - 29
Rab1A belongs to the small Rab GTPase family and is involved in the lifecycle of numerous viruses. Here, knockdown of Rab1A inhibited CSFV growth. Further... 
Rab1A | Classical swine fever virus (CSFV) | NS5A | Viral particle assembly | NEUTRALIZING ANTIBODIES | MACROPHAGES | INFECTIOUS PARTICLES | REGION | TRANSMISSION | RNA-SYNTHESIS | REPLICATION | VIROLOGY | NS5A PROTEIN | INTERACTS | GOLGI-COMPLEX | Proteins | Hog cholera | Swine | Genomics | Protein binding
Journal Article