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CELL RESEARCH, ISSN 1001-0602, 03/2017, Volume 27, Issue 3, pp. 444 - 447
Journal Article
by Wang, X and Feng, J and Xue, Y and Guan, ZY and Zhang, DL and Liu, Z and Gong, Z and Wang, Q and Huang, JB and Tang, C and Zou, TT and Yin, P
NATURE, ISSN 0028-0836, 06/2016, Volume 534, Issue 7608, pp. 575 - 575
Chemical modifications of RNA have essential roles in a vast range of cellular processes(1-3). N-6-methyladenosine (m(6)A) is an abundant internal modification... 
WIDESPREAD | N-6-METHYLADENOSINE | N6-METHYLADENOSINE | METHYLTRANSFERASE | MESSENGER-RNA METHYLATION | DNA | EPITRANSCRIPTOME | MULTIDISCIPLINARY SCIENCES | NUCLEAR-RNA | REVEALS
Journal Article
NATURE, ISSN 0028-0836, 02/2017, Volume 542, Issue 7642, pp. 475 - 475
The maternal-to-zygotic transition (MZT) is one of the most profound and tightly orchestrated processes during the early life of embryos, yet factors that... 
METHYLATION | TRANSCRIPTOME | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | NUCLEAR-RNA | REVEALS
Journal Article
by Xu, C and Wang, X and Liu, K and Roundtree, IA and Tempel, W and Li, YJ and Lu, ZK and He, C and Min, JR
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 11/2014, Volume 10, Issue 11, pp. 927 - 929
N-6-methyladenosine (m(6)A) is the most abundant internal modification of nearly all eukaryotic mRNAs and has recently been reported to be recognized by the... 
METHYLATION | N6-METHYLADENOSINE | PROTEIN | MESSENGER-RNA | BIOCHEMISTRY & MOLECULAR BIOLOGY | MEIOSIS | SITES | NUCLEAR-RNA | REVEALS
Journal Article
CANCER CELL, ISSN 1535-6108, 04/2017, Volume 31, Issue 4, pp. 591 - 591
The dynamic and reversible N-6-methyladenosine (m(6)A) RNA modification installed and erased by N-6-methyltransferases and demethylases regulates gene... 
N-6-METHYLADENOSINE | MESSENGER-RNA METHYLATION | TRANSCRIPTOME | ONCOLOGY | GLIOMA | CROSS-LINKING | NUCLEAR-RNA | BINDING PROTEIN HUR | TRANSLATION | PROMOTES | REVEALS | CELL BIOLOGY
Journal Article
NATURE, ISSN 0028-0836, 03/2017, Volume 543, Issue 7646, pp. 573 - 573
Cell proliferation and survival require the faithful maintenance and propagation of genetic information, which are threatened by the ubiquitous sources of DNA... 
POLYMERASE-KAPPA | N-6-METHYLADENOSINE | LOCALIZATION | REPAIR | N6-METHYLADENOSINE | HUMAN-CELLS | MULTIDISCIPLINARY SCIENCES | MOUSE | TRANSCRIPTION | POL-KAPPA | NUCLEAR-RNA
Journal Article
by Wang, X and Zhao, BS and Roundtree, IA and Lu, ZK and Han, DL and Ma, HH and Weng, XC and Chen, K and Shi, HL and He, C
CELL, ISSN 0092-8674, 06/2015, Volume 161, Issue 6, pp. 1388 - 1399
N-6-methyladenosine (m(6)A) is the most abundant internal modification in mammalian mRNA. This modification is reversible and non-stoichiometric and adds... 
MA RNA | MAPPING REVEALS | NUTRITIONAL CONTROL | BIOCHEMISTRY & MOLECULAR BIOLOGY | METHYLATED NUCLEOSIDES | GENE-EXPRESSION | YTH DOMAIN | NUCLEAR-RNA | BINDING PROTEIN | NUCLEOTIDE-SEQUENCES | STRESS GRANULES | CELL BIOLOGY
Journal Article
by Liu, N and Dai, Q and Zheng, GQ and He, C and Parisien, M and Pan, T
NATURE, ISSN 0028-0836, 02/2015, Volume 518, Issue 7540, pp. 560 - 564
RNA-binding proteins control many aspects of cellular biology through binding single-stranded RNA binding motifs (RBMs)(1-3). However, RBMs can be buried... 
METHYLATION | HNRNP C | MESSENGER-RNA | NUCLEOTIDE RESOLUTION | TRANSCRIPTOME | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | BINDING PROTEINS | SECONDARY STRUCTURE | NUCLEAR-RNA | REVEALS
Journal Article
by Cui, Q and Shi, HL and Ye, P and Li, L and Qu, QH and Sun, GQ and Sun, GH and Lu, ZK and Huang, Y and Yang, CG and Riggs, AD and He, C and Shi, YH
CELL REPORTS, ISSN 2211-1247, 03/2017, Volume 18, Issue 11, pp. 2622 - 2634
RNA modifications play critical roles in important biological processes. However, the functions of N-6-methyladenosine (m(6)A) mRNA modification in cancer... 
N-6-METHYLADENOSINE | ADENOSYL-L-METHIONINE | CANCER RISK | SUSCEPTIBILITY VARIANTS | METHYLTRANSFERASE | MESSENGER-RNA | SEX DETERMINATION | 5' TERMINUS | NUCLEAR-RNA | EXPRESSION | CELL BIOLOGY
Journal Article
NATURE REVIEWS GENETICS, ISSN 1471-0056, 05/2014, Volume 15, Issue 5, pp. 293 - 306
Cellular RNAs carry diverse chemical modifications that used to be regarded as static and having minor roles in 'fine-tuning' structural and functional... 
TUMOR 1-ASSOCIATING PROTEIN | YEAST TRANSFER-RNA | POSTTRANSCRIPTIONAL REGULATION | OBESITY-ASSOCIATED FTO | MAMMALIAN RNA | GENETICS & HEREDITY | ARABIDOPSIS MESSENGER-RNA | SIDEROBLASTIC ANEMIA MLASA | NUCLEAR-RNA | N-6-ADENOSINE METHYLATION | SACCHAROMYCES-CEREVISIAE
Journal Article
CELL STEM CELL, ISSN 1934-5909, 02/2018, Volume 22, Issue 2, pp. 191 - 191
N-6-methyladenosine (m(6)A), the most prevalent internal modification in eukaryotic messenger RNAs (mRNAs), plays critical roles in many bioprocesses. However,... 
TRANSCRIPTION FACTORS | METHYLATION | N6-METHYLADENOSINE | DATABASE | MUTATION | ENRICHMENT | MYELOID-LEUKEMIA | NUCLEAR-RNA | TRANSLATION | SUBUNIT | CELL & TISSUE ENGINEERING | CELL BIOLOGY
Journal Article
NATURE REVIEWS MOLECULAR CELL BIOLOGY, ISSN 1471-0072, 05/2014, Volume 15, Issue 5, pp. 313 - 326
N-6-methyladenosine (m(6)A) is a modified base that has long been known to be present in non-coding RNAs, ribosomal RNA, polyadenylated RNA and at least one... 
MOUSE L-CELLS | OBESITY-ASSOCIATED FTO | MESSENGER-RNA METHYLATION | OXIDATIVE DEMETHYLATION | SEQUENCE SPECIFICITY | SINGLE-NUCLEOTIDE RESOLUTION | SARCOMA VIRUS-RNA | HETEROGENEOUS NUCLEAR-RNA | RIBOSOMAL-RNA | N-6-ADENOSINE METHYLATION | CELL BIOLOGY
Journal Article
NATURE, ISSN 0028-0836, 12/2016, Volume 540, Issue 7632, pp. 242 - 242
N-6-methyladenosine RNA (m(6)A) is a prevalent messenger RNA modification in vertebrates. Although its functions in the regulation of post-transcriptional gene... 
N-6-METHYLADENOSINE | MESSENGER-RNA METHYLATION | GENE | MULTIDISCIPLINARY SCIENCES | EMBRYONIC STEM-CELLS | MAMMALIAN RNA | NUCLEAR-RNA | SACCHAROMYCES-CEREVISIAE | EXPRESSION | CENTRAL COMPLEX | REVEALS
Journal Article
by Li, XY and Xiong, XS and Wang, K and Wang, LX and Shu, XT and Ma, SQ and Yi, CQ
NATURE CHEMICAL BIOLOGY, ISSN 1552-4450, 05/2016, Volume 12, Issue 5, pp. 311 - 311
N-1-Methyladenosine (m(1)A) is a prevalent post-transcriptional RNA modification, yet little is known about its abundance, topology and dynamics in mRNA. Here,... 
N-6-METHYLADENOSINE | N6-METHYLADENOSINE | METHYLTRANSFERASE | MESSENGER-RNA METHYLATION | OXIDATIVE DEMETHYLATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | NUCLEAR-RNA | BASE MODIFICATION | RIBOSOMAL-RNA | ALKYLATION DAMAGE | 1-METHYLADENOSINE
Journal Article
CELL, ISSN 0092-8674, 01/2018, Volume 172, Issue 1-2, pp. 90 - 90
R-2-hydroxyglutarate (R-2HG), produced at high levels by mutant isocitrate dehydrogenase 1/2 (IDH1/2) enzymes, was reported as an oncometabolite. We show here... 
GLIOMA-CELLS | RNA METHYLATION | INHIBITION | INITIATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | IDH MUTATION | C-MYC | HEMATOPOIETIC DIFFERENTIATION | ACUTE MYELOID-LEUKEMIA | NUCLEAR-RNA | ONCOMETABOLITE 2-HYDROXYGLUTARATE | CELL BIOLOGY
Journal Article
NATURE IMMUNOLOGY, ISSN 1529-2908, 02/2019, Volume 20, Issue 2, pp. 173 - 173
N-6-methyladenosine (m(6)A) is the most common mRNA modification. Recent studies have revealed that depletion of m(6)A machinery leads to alterations in the... 
N6-METHYLADENOSINE | MESSENGER-RNA METHYLATION | RECOGNITION | METHYLOMES | GENE-EXPRESSION | DYNAMICS | NUCLEAR-RNA | IMMUNOLOGY | TRANSLATION | RECEPTORS | REVEALS
Journal Article
NUCLEIC ACIDS RESEARCH, ISSN 0305-1048, 06/2017, Volume 45, Issue 10, pp. 6051 - 6063
N-6-methyladenosine (m(6)A) is the most abundant internal modification in eukaryotic messenger RNA (mRNA), and affects almost every stage of the mRNA life... 
MA RNA | CELL-FREE FORMATION | N6-METHYLADENOSINE | PAR-CLIP | BIOCHEMISTRY & MOLECULAR BIOLOGY | YTH DOMAIN | SEX DETERMINATION | SPLICE-SITE | NUCLEAR-RNA | RBMX GENE | PRE-MESSENGER-RNA | RNA
Journal Article
by Wan, RX and Yan, CY and Bai, R and Wang, L and Huang, M and Wong, CCL and Shi, YG
SCIENCE, ISSN 0036-8075, 01/2016, Volume 351, Issue 6272, pp. 466 - 475
Splicing of precursor messenger RNA is accomplished by a dynamic megacomplex known as the spliceosome. Assembly of a functional spliceosome requires a... 
METAL-ION CATALYSIS | 3-DIMENSIONAL STRUCTURE | SMALL NUCLEAR-RNA | EM STRUCTURE | ACTIVE-SITE | CRYSTAL-STRUCTURE | EXON-LIGATION | MULTIDISCIPLINARY SCIENCES | ELECTRON-MICROSCOPY | YEAST SPLICEOSOME | PRE-MESSENGER-RNA
Journal Article
TRENDS IN CELL BIOLOGY, ISSN 0962-8924, 02/2018, Volume 28, Issue 2, pp. 113 - 127
N-6-Methyladenosine (m(6)A) is the most prevalent post-transcriptional modification of eukaryotic mRNA and long noncoding RNA. m(6)A mediates its effects... 
MESSENGER-RNA METHYLATION | RECOGNITION | STRUCTURAL BASIS | EMBRYONIC STEM-CELLS | YTH DOMAIN | SEX DETERMINATION | NUCLEAR-RNA | DYNAMIC N-1-METHYLADENOSINE METHYLOME | TRANSLATION | REVEALS | CELL BIOLOGY
Journal Article
Journal of immunology (Baltimore, Md. : 1950), ISSN 0022-1767, 3/2013, Volume 190, Issue 6, pp. 2747 - 2755
Mycobacterium tuberculosis infection alters macrophage gene expression and macrophage response to interferon gamma (IFNγ), a critical host defense cytokine.... 
macrophage | nuclear RNA | transcriptome
Journal Article
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