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Nature Chemical Biology, ISSN 1552-4450, 05/2015, Volume 11, Issue 5, pp. 316 - 318
Directly modulating the activity of genome-editing proteins has the potential to increase their specificity by reducing activity following target locus... 
NUCLEASE SPECIFICITY | RNA | NICKASES | HUMAN-CELLS | BIOCHEMISTRY & MOLECULAR BIOLOGY | CLEAVAGE | DIRECTED EVOLUTION | MAMMALIAN-CELLS | DELIVERY | INTEIN
Journal Article
Nature, ISSN 0028-0836, 02/2016, Volume 530, Issue 7588, pp. 113 - 116
Journal Article
Journal Article
Nature, ISSN 0028-0836, 04/2018, Volume 556, Issue 7699, pp. 57 - 63
Journal Article
Nature Reviews Genetics, ISSN 1471-0056, 05/2016, Volume 17, Issue 5, pp. 300 - 312
Journal Article
Cell, ISSN 0092-8674, 09/2013, Volume 154, Issue 6, pp. 1380 - 1389
Targeted genome editing technologies have enabled a broad range of research and medical applications. The Cas9 nuclease from the microbial CRISPR-Cas system is... 
SYSTEM | CELLS | BACTERIA | BIOCHEMISTRY & MOLECULAR BIOLOGY | GENERATION | KNOCKOUT | NUCLEASE | CELL BIOLOGY | Streptococcus pyogenes - genetics | Gene Targeting - methods | Animals | RNA, Guide - genetics | Base Sequence | Streptococcus pyogenes - enzymology | Zygote - metabolism | Molecular Sequence Data | Mice | Genome | DNA Breaks, Double-Stranded | RNA | Genomics | Index Medicus
Journal Article