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JOURNAL OF VIROLOGY, ISSN 0022-538X, 10/2019, Volume 93, Issue 19
Cellular and viral factors participate in the replication cycle of rotavirus. We report that the guanine nucleotide exchange factor GBF1, which activates the... 
GENOME REPLICATION | PROTEIN | GLYCOPROTEIN VP7 | SCREEN REVEALS | GBF1 nucleotide exchange factor | morphogenesis | ADP-RIBOSYLATION FACTORS | RECYCLING ENDOSOMES | VIROLOGY | ARF | rotavirus | SEC7 DOMAIN | BREFELDIN-A | BETA-COP
Journal Article
ELIFE, ISSN 2050-084X, 04/2015, Volume 4, p. e07314
The general translation initiation factor eIF2 is a major translational control point. Multiple signaling pathways in the integrated stress response... 
GUANINE-NUCLEOTIDE-EXCHANGE | UNFOLDED PROTEIN RESPONSE | 40S RIBOSOMAL-SUBUNIT | OPEN READING FRAMES | MESSENGER-RNA | BIOLOGY | TRANSLATION INITIATION | INITIATION-FACTOR EIF2B | VANISHING WHITE-MATTER | MAMMALIAN-CELLS | GENETIC INTERACTION MAPS | RNA, Small Interfering - genetics | Phosphorylation | Humans | Thapsigargin - antagonists & inhibitors | Acetamides - pharmacology | Structure-Activity Relationship | Protein Subunits - metabolism | Acetamides - chemical synthesis | Neuroprotective Agents - pharmacology | Cyclohexylamines - pharmacology | Eukaryotic Initiation Factor-2B - genetics | HEK293 Cells | Binding Sites | Genes, Reporter | Protein Subunits - genetics | Gene Expression | Neuroprotective Agents - chemistry | Cyclohexylamines - chemical synthesis | Endoplasmic Reticulum Stress - drug effects | Bacterial Proteins - genetics | Cyclohexylamines - chemistry | Nootropic Agents - chemical synthesis | Nootropic Agents - chemistry | Neuroprotective Agents - chemical synthesis | Acetamides - chemistry | High-Throughput Screening Assays | K562 Cells | Protein Binding | Thapsigargin - pharmacology | Bacterial Proteins - metabolism | Luminescent Proteins - genetics | Eukaryotic Initiation Factor-2B - metabolism | Protein Subunits - antagonists & inhibitors | HeLa Cells | Eukaryotic Initiation Factor-2B - antagonists & inhibitors | Nootropic Agents - pharmacology | Protein Multimerization - drug effects | Luminescent Proteins - metabolism | RNA, Small Interfering - metabolism | Cell culture | Transcription factors | Neurodegenerative diseases | Serine | Translation initiation | Cognitive ability | Kinases | Proteins | Protein synthesis | Stress response | Dimerization | Long-term depression | Binding sites
Journal Article
06/2014
The Rho family small GTPases are key regulators of the cytoskeleton, through which they impact and control many vital cellular functions, including growth,... 
Tumour Necrosis Factor-alpha (TNF) | Rho GTPases | 0379 | Hyperosmotic stress | GEF-H1 | 0307 | Cytoskeletal remodelling | Guanine Nucleotide Exchange Factors
Dissertation
Science, ISSN 0036-8075, 03/2018, Volume 359, Issue 6383, pp. 1483 - 1483
Regulation by the integrated stress response (ISR) converges on the phosphorylation of translation initiation factor eIF2 in response to a variety of stresses.... 
COMPLEX | INHIBITION | ALPHA-SUBUNIT | CRYSTAL-STRUCTURE | MULTIDISCIPLINARY SCIENCES | REGULATORY SUBCOMPLEX | ARCHITECTURE | INITIATION-FACTOR EIF2B | EIF2-ALPHA | TRANSLATIONAL CONTROL | INSIGHTS | Memory - drug effects | Phosphorylation | Recombinant Proteins - ultrastructure | Escherichia coli | Humans | Cyclohexylamines - chemistry | Recombinant Proteins - chemistry | Acetamides - pharmacology | Recombinant Proteins - genetics | Nootropic Agents - chemistry | Protein Folding | Cryoelectron Microscopy | Eukaryotic Initiation Factor-2B - chemistry | Acetamides - chemistry | Cyclohexylamines - pharmacology | Protein Stability - drug effects | Eukaryotic Initiation Factor-2B - genetics | Protein Conformation | Eukaryotic Initiation Factor-2B - ultrastructure | Mutation | Nootropic Agents - pharmacology | Protein Multimerization - drug effects | Neuroimaging | Exchanging | Brain | Regulations | Atomic force microscopy | Traumatic brain injury | Target recognition | Disorders | Cognitive ability | Nervous system | Cognition | Ultracentrifugation | Guanine | Convergence | Analogs | Proteins | Head injuries | Synthesis | Rodents | Atomic structure | Guanine nucleotide exchange factor | Stress response | Dimerization | Assembly | Symmetry | Stresses | Enzymes | Translation | Translation initiation | Pharmacology | Electron microscopy | Sedimentation | Chemical compounds | Substrates | Mutants | Neurological diseases | Transmission electron microscopy | Composite materials | Inhibitors | Cognition & reasoning | Microscopy | Ionic strength | Dismantling | Binding sites
Journal Article
Science, ISSN 0036-8075, 03/2018, Volume 359, Issue 6383, pp. 1533 - 1536
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2017, Volume 127, Issue 12, pp. 4516 - 4526
Journal Article
Science, ISSN 0036-8075, 9/2009, Volume 325, Issue 5945, pp. 1261 - 1265
Journal Article
Journal Article
Journal Article