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PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, ISSN 0027-8424, 03/2004, Volume 101, Issue 12, pp. 4041 - 4046
The RImA class of enzymes (RImA(I) and RImA(II)) catalyzes N1-methylation of a guanine base (G745 in Gram-negative and G748 in Gram-positive bacteria) of... 
ANGSTROM RESOLUTION | MACROMOLECULAR STRUCTURES | METHYLTRANSFERASE | PROTEIN | MULTIDISCIPLINARY SCIENCES | ESCHERICHIA-COLI | RESISTANCE | NUCLEOTIDE G745 | STREPTOMYCES-FRADIAE | TYLOSIN | SUBUNIT
Journal Article
ENVIRONMENTAL MICROBIOLOGY, ISSN 1462-2912, 12/2018, Volume 20, Issue 12, pp. 4431 - 4443
American foulbrood (AFB) and European foulbrood (EFB) caused by Paenibacillus larvae and Melissococcus plutonius, respectively, are major bacterial infections... 
METHYLATION | CAUSATIVE AGENT | POPULATION-STRUCTURE | NUCLEOTIDE G745 | MICROBIOLOGY | STREPTOMYCES-FRADIAE | MACROLIDE ANTIBIOTICS | TYLOSIN-RESISTANCE | AMERICAN FOULBROOD | PAENIBACILLUS-LARVAE | TETRACYCLINE-RESISTANCE
Journal Article
JOURNAL OF BACTERIOLOGY, ISSN 0021-9193, 01/1998, Volume 180, Issue 2, pp. 359 - 365
An Escherichia coli mutant lacking the modified nucleotide m(1)G in rRNA has previously been isolated (G. R. Bjork and L. A. Isaksson, J. Mel. Biol. 51:83-100,... 
STRAINS | NUCLEOTIDES | VIOMYCIN | METHYLATION | SEQUENCES | CLONING | RESISTANCE | MICROBIOLOGY | PROTEINS | 16S RIBOSOMAL-RNA
Journal Article
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 07/2001, Volume 310, Issue 5
Methylation of the N1 position of nucleotide G745 in hairpin 35 of Escherichia coli 23 S ribosomal RNA (rRNA) is mediated by the methyltransferase enzyme RrmA.... 
Drug resistance in microorganisms | Methyltransferases | Ionization | Ribosomal RNA | Escherichia coli | Protein biosynthesis | Nucleotides | Molecular biology | Methylation | Mass spectrometry | S-adenosylmethionine
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 07/2001, Volume 310, Issue 5
To access, purchase, authenticate, or subscribe to the full-text of this article, please visit this link: http://dx.doi.org/10.1006/jmbi.2001.4836 Methylation... 
Fibronectins | Methyltransferases | Ribosomal RNA | Escherichia coli | Protein biosynthesis | Nucleotides | Drug resistance | Methylation | Mass spectrometry
Journal Article
JOURNAL OF MOLECULAR BIOLOGY, ISSN 0022-2836, 05/2008, Volume 378, Issue 5, pp. 969 - 975
RlmA(II) methylates the NI-position of nucleotide G748 in hairpin 35 of 23 S rRNA. The resultant methyl group extends into the peptide channel of the 50 S... 
RECOGNITION | CRYSTAL-STRUCTURE | BIOCHEMISTRY & MOLECULAR BIOLOGY | ESCHERICHIA-COLI | NUCLEOTIDE G745 | STREPTOMYCES-FRADIAE | TLRB | methyltransferases | ANGSTROM RESOLUTION | 23S | GENE | protein-RNA interaction | drug resistance | chemical footprinting | rRNA structure | SUBUNIT
Journal Article
PLoS ONE, ISSN 1932-6203, 03/2014, Volume 9, Issue 3, pp. e91308 - e91308
Background/Aims: An increase of ethanol metabolism and hepatic mitochondrial respiration occurs in vivo after a single binge of alcohol. Here, our aim was to... 
OXIDATIVE STRESS | REACTIVE OXYGEN | SWIFT INCREASE | PERMEABILITY TRANSITION INHIBITOR | ACETALDEHYDE ADDUCTS | MULTIDISCIPLINARY SCIENCES | ALCOHOLIC LIVER-DISEASE | PERFUSED-RAT-LIVER | N-METHYL-4-ISOLEUCINE CYCLOSPORINE | STIMULATES GLYCOGENOLYSIS | INDUCED FAT ACCUMULATION | Alcohol Dehydrogenase - metabolism | Ethanol - metabolism | Fatty Liver - metabolism | Oxidative Stress | Hypoxia-Inducible Factor 1, alpha Subunit - genetics | Mitochondria, Liver - metabolism | Liver - metabolism | Cytochrome P-450 Enzyme System - metabolism | Male | Hepatocytes - metabolism | Permeability | Hypoxia - metabolism | Mice, Knockout | Dose-Response Relationship, Drug | Mitochondria, Liver - drug effects | Ethanol - pharmacology | Animals | Liver - drug effects | Cation Transport Proteins - metabolism | Hypoxia-Inducible Factor 1, alpha Subunit - metabolism | Adenosine Triphosphate - metabolism | Cation Transport Proteins - genetics | Mice | Intracellular Membranes - metabolism | Alcohol, Denatured | Pyridine | Cell death | Cytochrome P-450 | Physiological aspects | Alcohol | Nucleotides | Acetaldehyde | Cytochrome | Rhodamine | Polarization | Phosphorylation | Dehydrogenases | Liver | Fluorescence | Propidium iodide | Activation | Alcohol dehydrogenase | Confocal | Kinases | Dehydrogenase | Aldehyde dehydrogenase | Depolarization | Mitochondria | Fatty liver | Metabolites | Rodents | Gastroenterology | Pyridine nucleotides | Calcein | Pyridines | Liver diseases | Ethanol | Iodides | Histology | Metabolism | Steatosis | DNA nucleotidylexotransferase | NAD | Microscopy | Hepatocytes | In vivo methods and tests | Electron transport | Respiration | Cancer | Apoptosis | Index Medicus
Journal Article
Journal Article
PLOS ONE, ISSN 1932-6203, 08/2014, Volume 9, Issue 8, pp. e104156 - e104156
Abnormalities in eNOS gene, possibly interacting with high fat diet (HFD), affect peripheral vascular function and glucose metabolism. The relative role of... 
ENDOTHELIAL DYSFUNCTION | NITRIC-OXIDE SYNTHASE | MULTIDISCIPLINARY SCIENCES | RESISTANCE | RISK | AKT | POLYMORPHISM | HYPERTENSION | EXPRESSION | MICE LACKING | ARTERY-DISEASE | Body Weight | Coronary Vessels - physiopathology | Male | Extracellular Signal-Regulated MAP Kinases - metabolism | Insulin - blood | Nitric Oxide Synthase Type III - deficiency | Coronary Vessels - metabolism | Diet, High-Fat | Gene Deletion | Female | Nitric Oxide Synthase Type III - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Hyperinsulinism - blood | Hyperinsulinism - physiopathology | Coronary Vessels - pathology | Glucose Tolerance Test | Vascular Resistance | Hyperinsulinism - complications | Signal Transduction | Mice, Inbred C57BL | Myocardium - pathology | Nitric Oxide Synthase Type III - genetics | Mice, Knockout | Insulin - metabolism | Myocardium - enzymology | Animals | Models, Biological | Blood Glucose - metabolism | In Vitro Techniques | Nitric Oxide Synthase Type II - metabolism | Heart | Unbalance | Hyperinsulinemia | AKT protein | Single-nucleotide polymorphism | Glucose | Gene deletion | Vasodilation | High fat diet | Infusion | Glucose metabolism | Signal transduction | Pathways | Clonal deletion | Rodents | Deletion | Blood pressure | Heart diseases | Genetic modification | Abnormalities | Diabetes mellitus | Extracellular signal-regulated kinase | Blood vessels | Gene expression | Metabolism | Insulin | Endothelium | Glucose tolerance | Signaling | Diet | Sodium | Nitric oxide | Insulin resistance | Acetylcholine | Mice | Index Medicus
Journal Article
American Journal of Physiology - Gastrointestinal and Liver Physiology, ISSN 0193-1857, 11/1994, Volume 267, Issue 5, pp. 745 - 753
We previously reported that intestine from rats sensitized to ovalbumin (Ova), using Bordetella pertussis vaccine as adjuvant, demonstrated a rapid secretory... 
immunoglobulin E | mast cells | IMMUNOGLOBULIN E | NUCLEOTIDE-BINDING-PROTEINS | EPITHELIUM INVITRO | PHYSIOLOGY | JEJUNAL MUCOSA | IGE | MAST-CELLS | MAST CELLS | IMMEDIATE HYPERSENSITIVITY | RESPONSES | ION-TRANSPORT ABNORMALITIES | ALLERGIC REACTIONS | GASTROENTEROLOGY & HEPATOLOGY | ANAPHYLAXIS
Journal Article
Systems Biology in Reproductive Medicine, ISSN 1939-6368, 07/2019, Volume 65, Issue 4, pp. 288 - 300
Methionine synthase encoded by the MTR gene is one of the key enzymes involved in the SAM (S- Adenosyl Methionine) cycle catalyzing the conversion of... 
deleterious prediction | Computational analysis | single nucleotide polymorphisms | folate metabolism | human MTR gene polymorphism | HOMOCYSTEINE | ANDROLOGY | MATERNAL RISK | REDUCTASE A66G | REPRODUCTIVE BIOLOGY | POLYMORPHISMS | DELETERIOUS NSSNPS | DOWN-SYNDROME | NON-SYNONYMOUS SNPS | MUTATIONS | PROTEIN STABILITY CHANGES
Journal Article