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Journal Article
The Journal of Physiology, ISSN 0022-3751, 04/2013, Volume 591, Issue 8, pp. 2067 - 2086
Journal Article
British Journal of Pharmacology, ISSN 0007-1188, 12/2014, Volume 171, Issue 24, pp. 5665 - 5681
Background and Purpose Augmented Na+/Ca2+ exchanger (NCX) activity may play a crucial role in cardiac arrhythmogenesis; however, data regarding the... 
TORSADES-DE-POINTES | CANINE VENTRICULAR CARDIOMYOCYTES | I-NA | HEART-FAILURE | CARDIAC MYOCYTES | KB-R7943 | RECTIFIER POTASSIUM CURRENT | PHARMACOLOGY & PHARMACY | SODIUM-CALCIUM EXCHANGE | GUINEA-PIGS | REPOLARIZATION RESERVE | Prevention | Arrhythmia | Analysis | Anti-arrhythmia drugs | Research Papers
Journal Article
Journal Article
World Journal of Gastroenterology, ISSN 1007-9327, 2019, Volume 25, Issue 3, pp. 287 - 299
The Na+/Ca2+ exchanger (NCX) protein family is a part of the cation/Ca2+ exchanger superfamily and participates in the regulation of cellular Ca2+ homeostasis.... 
Na+/Ca2+ exchanger | Calcium | Sodium | exchanger | Digestive system diseases | Ion channel | Ca | PLASMA-MEMBRANE CA2+-ATPASE | CARDIAC NA+-CA2+ EXCHANGER | GASTRIC FUNDUS | SUSTAINED RELAXATION | NA/CA EXCHANGE | BETA-CELL FUNCTION | DISPLAY INCREASED RELAXATION | NITRIC-OXIDE | SODIUM-CALCIUM EXCHANGE | GASTROENTEROLOGY & HEPATOLOGY | MOLECULAR-MECHANISMS | Ca2+ exchanger | Na+ | Review
Journal Article
Pigment Cell & Melanoma Research, ISSN 1755-1471, 01/2019, Volume 32, Issue 1, pp. 55 - 67
NCKX5 is a bidirectional K+‐dependent Na+–Ca2+ exchanger, which belongs to the SLC24A gene family. In particular, the A111T mutation of NCKX5 has been... 
pigmentation | NCKX5 | cytoplasmic loop | MNT1 | TGN | Na+/Ca2+–K+ exchanger | SLC24A5 | Na | exchanger | K | Ca | TOPOLOGY | TGN38 | DOMAIN | Na+/Ca2+-K+ exchanger | PROTEIN | FAMILY | MELANOSOMES | CELL BIOLOGY | DERMATOLOGY | ONCOLOGY | NA+/CA2+ EXCHANGER | TRANS-GOLGI NETWORK | RESIDUES | Calcium | Melanosomes | Pigmentation | Mutants | Golgi apparatus | Na+/Ca2+-exchanging ATPase | Clonal deletion | Isoforms | Deletion | Intracellular | Chimeras | Localization | Calcium ions
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 12/2012, Volume 343, Issue 3, pp. 596 - 607
Using a fluorescent viability assay, immunocytochemistry, patch-clamp recordings, and Ca2+ imaging analysis, we report that ouabain, a specific ligand of the... 
SKELETAL-MUSCLE | GLUTAMATE NEUROTOXICITY | NA+/CA2+ EXCHANGE | NA,K-ATPASE | NICOTINIC ACETYLCHOLINE-RECEPTOR | BINDING-SITE | PHARMACOLOGY & PHARMACY | D-ASPARTATE RECEPTOR | CULTURED CORTICAL-NEURONS | BRAIN NEURONS | CELL-DEATH | Immunohistochemistry | Neurons - pathology | Rats, Wistar | Apoptosis - drug effects | Calcium - metabolism | Kainic Acid - administration & dosage | Cerebral Cortex - cytology | Excitatory Postsynaptic Potentials - drug effects | Cerebral Cortex - metabolism | N-Methylaspartate - pharmacology | Dose-Response Relationship, Drug | Proto-Oncogene Proteins c-bcl-2 - metabolism | Neuroprotective Agents - pharmacology | Sodium-Calcium Exchanger - metabolism | Cell Membrane - pathology | Cell Membrane - metabolism | Neurons - metabolism | Ouabain - administration & dosage | Cell Culture Techniques | Cerebral Cortex - drug effects | Neurons - drug effects | Neuroprotective Agents - administration & dosage | Binding Sites | Cell Membrane - drug effects | Ouabain - pharmacology | Cell Survival - drug effects | Kainic Acid - pharmacology | Cells, Cultured | Rats | Electrical Synapses | N-Methylaspartate - administration & dosage | Excitatory Amino Acid Agonists - pharmacology | Excitatory Amino Acid Agonists - administration & dosage | Microscopy, Confocal | Sodium-Potassium-Exchanging ATPase - metabolism | Patch-Clamp Techniques | Animals | Microscopy, Fluorescence
Journal Article
Journal of Biological Chemistry, ISSN 0021-9258, 03/2006, Volume 281, Issue 12, pp. 7784 - 7792
We have demonstrated previously that phospholemman (PLM), a 15-kDa integral sarcolemmal phosphoprotein, inhibits the cardiac Na+/Ca2+ exchanger (NCX1). In... 
ADULT-RAT MYOCYTES | POSTINFARCTION MYOCYTES | ALTERS CONTRACTILITY | PROTEIN-KINASE-C | (I) TRANSIENTS | DEPENDENT REGULATION | BIOCHEMISTRY & MOLECULAR BIOLOGY | DOWN-REGULATION | NA+-CA2+ EXCHANGER | NA/CA EXCHANGE | VENTRICULAR MYOCYTES | Phosphorylation | Sodium - chemistry | Humans | Alanine - chemistry | Immunoblotting | Sodium-Calcium Exchanger - genetics | Phosphoproteins - metabolism | Transfection | Membrane Proteins - physiology | Myocardium - metabolism | Cloning, Molecular | Membrane Proteins - metabolism | Phosphoproteins - physiology | Muscles - metabolism | Tetradecanoylphorbol Acetate - chemistry | Cyclic AMP-Dependent Protein Kinases - metabolism | Cell Line | Colforsin - chemistry | Colforsin - pharmacology | Sodium-Calcium Exchanger - chemistry | Muscle Cells - metabolism | Ions | Sodium-Calcium Exchanger - physiology | Serine - chemistry | Calsequestrin - chemistry | Mice, Knockout | Animals | Adenosine Triphosphatases - chemistry | Mice | Mutation | Glutamic Acid - chemistry | HEPES, N-2-hydroxyethylpiperazine-N’-2-ethanesulfonic acid | WT, wild-type | SDS-PAGE, sodium dodecyl sulfate- polyacrylamide gel electrophoresis | HEK, human embryonic kidney | EGTA, ethylene glycol-bis-(β-aminoethyl ether)N,N,N’,N’-tetraacetic acid | INaCa, Na+, Ca2+ exchange current | ENaCa, equilibrium potential for Na+, Ca2+ exchange current | PVDF, polyvinylidene difluoride | MEM, minimal essential media | ANOVA, analysis of variance | Em, membrane potential | GFP, green fluorescent protein | NIMA, never in mitosis A | [Ca2+]o, extracellular Ca2+ concentration; Cm, whole cell membrane capacitance | PKC, protein kinase C | SR, sarcoplasmic reticulum | NCX1, Na+, Ca2+ exchanger | FBS, fetal bovine serum | ex., excitation | 8-Br-cAMP, 8-bromoadenosine 3′, 5′ cyclic monophosphate | em., emission | Vmax, maximum velocity | DMSO, dimethylsulfoxide | PMSF, phenylmethylsulfonyl fluoride | DMEM, Dulbecco’s modified Eagle’s medium | SERCA2, sarco(endo)plasmic reticulum Ca2+-ATPase | KO, knock-out | SE, standard error | CMV, cytomegalovirus | PLM, phospholemman | PKA, protein kinase A | PMA, phorbol 12-myristate 13-acetate
Journal Article
Molecular Biology and Evolution, ISSN 0737-4038, 09/2004, Volume 21, Issue 9, pp. 1692 - 1703
Journal Article
Advances in Experimental Medicine and Biology, ISSN 0065-2598, 2016, Volume 898, pp. 67 - 85
Na(+)/Ca(2+) exchangers (NCXs) have traditionally been viewed principally as a means of Ca(2+) removal from non-excitable cells. However there has recently... 
Calcium entry | Na | Reverse mode NCX activity | TRPC channels | Sodium entry | exchangers | Ca | Na+/Ca2+ exchangers | Ion Transport | Sodium - metabolism | Calcium - metabolism | Sodium-Calcium Exchanger - metabolism | Humans | TRPC Cation Channels - metabolism
Journal Article
European Journal of Medicinal Chemistry, ISSN 0223-5234, 02/2016, Volume 109, pp. 114 - 123
The mitochondrial Na /Ca exchanger plays an important role in the control of cytosolic Ca cycling in excitable cells, essential for the regulation of a... 
Pyridothiazepines | Neuroprotection | Mitochondria | Neurodegeneration | Mitochondrial Na+/Ca2+ exchanger | CGP37157 | Mitochondrial Na/Ca2 exchanger | CA2+ ENTRY | CHEMISTRY, MEDICINAL | SODIUM-CALCIUM EXCHANGER | ALZHEIMERS-DISEASE | STRATEGY | CELL-DEATH | INNER-MEMBRANE | NEURONS | BENZOTHIAZEPINE CGP37157 | REGULATORS | INHIBITORS
Journal Article