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Neuropsychopharmacology, ISSN 0893-133X, 11/2013, Volume 38, Issue 12, pp. 2484 - 2497
Activation of kappa-opioid receptors (KORs) in monoamine circuits results in dysphoria-like behaviors and stress-induced reinstatement of drug seeking in both... 
norepinephrine | kappa-opioid receptor | cocaine | reinstatement | locus coeruleus | b-adrenergic receptors | AGONIST SALVINORIN | PRESYNAPTIC INHIBITION | PSYCHIATRY | P38 MAPK | NEUROSCIENCES | BED NUCLEUS | PREFRONTAL CORTEX | CORTICOTROPIN-RELEASING-FACTOR | STRIA TERMINALIS | STRESS-INDUCED REINSTATEMENT | AXON TERMINALS | beta-adrenergic receptors | PHARMACOLOGY & PHARMACY | SALVINORIN-A | Naltrexone - analogs & derivatives | Adrenergic beta-1 Receptor Antagonists - pharmacology | Locus Coeruleus - drug effects | Male | Adrenergic alpha-2 Receptor Agonists - pharmacology | Adrenergic beta-Antagonists - pharmacology | Drug-Seeking Behavior | Naltrexone - pharmacology | Propranolol - pharmacology | Clonidine - pharmacology | Receptors, Adrenergic, beta - metabolism | Receptors, Adrenergic, alpha - metabolism | Receptors, Opioid, kappa - antagonists & inhibitors | Conditioning (Psychology) - drug effects | Mice, Inbred C57BL | Receptors, Opioid, kappa - agonists | Receptors, Opioid, kappa - metabolism | 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer - pharmacology | Cocaine - administration & dosage | Cocaine - pharmacology | Animals | Mice | Betaxolol - pharmacology | Propanolamines - pharmacology | Locus Coeruleus - metabolism | Index Medicus | Adrenergic receptors | beta adrenergic receptors | kappa opioid receptor | Catecholamines | Neuropharmacology | behavioral Science | Original | β-adrenergic receptors | opioids
Journal Article
Journal Article
Journal Article
Clinical and Experimental Pharmacology and Physiology, ISSN 0305-1870, 01/2008, Volume 35, Issue 1, pp. 97 - 102
1 The aims of the present study were to determine whether δ‐opioid receptor stimulation enhanced proliferation of and to investigate the role of the... 
extracellular signal‐regulated kinase | myocardial cells | δ‐opioid receptor | proliferation | DNA | protein kinase A | protein kinase C | Protein kinase A | Protein kinase C | Myocardial cells | Extracellular signal-regulated kinase | δ-opioid receptor | Proliferation | extracellular signal-regulated kinase | PHYSIOLOGY | ACTIVATED PROTEIN-KINASE | delta-opioid receptor | PHOSPHORYLATION | FIBROBLASTS | INHIBITION | NG108-15 CELLS | CARDIAC-HYPERTROPHY | PHARMACOLOGY & PHARMACY | SMOOTH-MUSCLE-CELLS | S6 KINASE | CAMP | Naltrexone - analogs & derivatives | Receptors, Opioid, delta - metabolism | Phosphorylation | Nitriles - pharmacology | Analgesics, Opioid - pharmacology | Extracellular Signal-Regulated MAP Kinases - antagonists & inhibitors | Extracellular Signal-Regulated MAP Kinases - metabolism | Dose-Response Relationship, Drug | Myocytes, Cardiac - enzymology | Naltrexone - pharmacology | Cyclic AMP - analogs & derivatives | Time Factors | Protein Kinase C - metabolism | Enkephalin, Leucine-2-Alanine - pharmacology | Cyclic AMP-Dependent Protein Kinases - antagonists & inhibitors | Animals, Newborn | Cyclic AMP-Dependent Protein Kinases - metabolism | Butadienes - pharmacology | Cells, Cultured | Rats | Protein Kinase C - antagonists & inhibitors | Thionucleotides - pharmacology | Rats, Sprague-Dawley | Cyclic AMP - pharmacology | Animals | Myocytes, Cardiac - drug effects | Signal Transduction - drug effects | Narcotic Antagonists - pharmacology | Myocytes, Cardiac - metabolism | Cell Proliferation - drug effects | Heart Ventricles - metabolism | Protein Kinase Inhibitors - pharmacology | Receptors, Opioid, delta - agonists | Cytoskeleton - drug effects | Staurosporine - pharmacology | Heart Ventricles - drug effects | Heart Ventricles, drug effects | Myocytes, Cardiac, drug effects | Thionucleotides, pharmacology | Signal Transduction, drug effects | Cell Proliferation, drug effects | Myocytes, Cardiac, enzymology | Heart Ventricles, metabolism | Receptors, Opioid, delta, metabolism | Analgesics, Opioid, pharmacology | Naltrexone, pharmacology | Naltrexone, analogs and derivatives | Cyclic AMP, analogs and derivatives | Extracellular Signal-Regulated MAP Kinases, antagonists and inhibitors | Protein Kinase C, metabolism | Cyclic AMP, pharmacology | Myocytes, Cardiac, metabolism | Extracellular Signal-Regulated MAP Kinases, metabolism | Butadienes, pharmacology | Protein Kinase Inhibitors, pharmacology | Staurosporine, pharmacology | Cyclic AMP-Dependent Protein Kinases, antagonists and inhibitors | Nitriles, pharmacology | Protein Kinase C, antagonists and inhibitors | Receptors, Opioid, delta, agonists | Cyclic AMP-Dependent Protein Kinases, metabolism | Cytoskeleton, drug effects | Enkephalin, Leucine-2-Alanine, pharmacology | Narcotic Antagonists, pharmacology | Index Medicus
Journal Article
Neuropsychopharmacology, ISSN 0893-133X, 02/2014, Volume 39, Issue 3, pp. 614 - 624
Journal Article
Journal Article
Psychopharmacology, ISSN 0033-3158, 1/2015, Volume 232, Issue 1, pp. 305 - 314
The novel opioid receptor antagonist, GSK1421498, has been shown to attenuate reward-driven compulsive behaviours, such as stimulant drug seeking or binge... 
μ-Opioid receptor | GSK1521498 | Neurosciences | Biomedicine | Pharmacology/Toxicology | Psychiatry | Inverse agonism | CELLS | RAT | MORPHINE | PSYCHIATRY | TOLERANCE | G-PROTEINS | NEUROSCIENCES | CHRONIC EXPOSURE | mu-Opioid receptor | 6-BETA-NALTREXOL | PHARMACOLOGY & PHARMACY | DOSE SAFETY | MODULATION | AGONIST | Naltrexone - analogs & derivatives | Naltrexone - therapeutic use | Cricetulus | Humans | Analgesics, Opioid - pharmacology | Male | Indans - therapeutic use | Compulsive Behavior - metabolism | Naltrexone - pharmacology | Narcotic Antagonists - metabolism | Compulsive Behavior - drug therapy | HEK293 Cells | CHO Cells | Naltrexone - metabolism | Triazoles - therapeutic use | Cricetinae | Naloxone - metabolism | Morphine - pharmacology | Receptors, Opioid, mu - metabolism | Indans - metabolism | Morphine - metabolism | Analgesics, Opioid - therapeutic use | Naloxone - therapeutic use | Treatment Outcome | Receptors, Opioid, mu - antagonists & inhibitors | Triazoles - pharmacology | Triazoles - metabolism | Guanosine 5'-O-(3-Thiotriphosphate) - metabolism | Animals | Narcotic Antagonists - therapeutic use | Naloxone - pharmacology | Narcotic Antagonists - pharmacology | Ligands | Mice | Analgesics, Opioid - metabolism | Reward | Morphine - therapeutic use | Indans - pharmacology | Protein Binding - physiology | Care and treatment | Compulsive eating | Morphine | Dosage and administration | Pharmacology | Research | Diagnosis | Narcotics | Antagonist drugs | Psychopharmacology | Index Medicus | Original Investigation
Journal Article