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Proceedings of the National Academy of Sciences - PNAS, ISSN 1091-6490, 2015, Volume 112, Issue 2, pp. E156 - E165
Current treatments to control pathological or unwanted immune responses often use broadly immunosuppressive drugs. New approaches to induce antigen-specific... 
Nanoparticles | Rapamycin | Anti-drug antibodies | Immune tolerance | Immunotherapy | THERAPEUTICS | anti-drug antibodies | IMMUNITY | TOLEROGENIC DENDRITIC CELLS | RISK-FACTORS | MULTIDISCIPLINARY SCIENCES | FACTOR-VIII | MECHANISMS | RESPONSES | immune tolerance | IMMUNOGENICITY | nanoparticles | UNRESPONSIVENESS | immunotherapy | rapamycin | Factor VIII - immunology | Oligodeoxyribonucleotides - administration & dosage | Nanoparticles - chemistry | Ovalbumin - immunology | Immunosuppression - methods | Nanocapsules - administration & dosage | Humans | Encephalomyelitis, Autoimmune, Experimental - immunology | Hypersensitivity, Delayed - immunology | Nanocapsules - chemistry | Peptides - administration & dosage | Antigens - administration & dosage | CD4-Positive T-Lymphocytes - immunology | Immunity, Humoral | Peptide Fragments - immunology | Proteins - administration & dosage | Female | Immunosuppressive Agents - administration & dosage | Disease Models, Animal | Lactic Acid - chemistry | Peptides - chemistry | Hemophilia A - immunology | Peptide Fragments - administration & dosage | Peptides - immunology | Immune Tolerance | Hemophilia A - therapy | Hypersensitivity, Delayed - therapy | Antigens - chemistry | Proteins - immunology | Encephalomyelitis, Autoimmune, Experimental - therapy | Sirolimus - administration & dosage | Animals | Ovalbumin - administration & dosage | Recombinant Proteins - immunology | Polyglycolic Acid - chemistry | Encephalomyelitis, Autoimmune, Experimental - prevention & control | Mice | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Hemocyanins - administration & dosage | Proteins - chemistry | Antigens | Usage | Research | Health aspects | Immunological tolerance | Immunological research | Biological Sciences | PNAS Plus
Journal Article
Biomaterials, ISSN 0142-9612, 2016, Volume 105, pp. 206 - 221
Abstract Oxidative stress, resulting from excessive generation of reactive oxygen species (ROS), plays a pivotal role in the initiation and progression of... 
Advanced Basic Science | Dentistry | Reactive oxygen species | Cyclodextrin | Responsive nanoparticles | Drug delivery | Colitis | Targeted therapy | MATERIALS SCIENCE, BIOMATERIALS | PERMEABILITY | INFLAMED TISSUE | ENGINEERING, BIOMEDICAL | CHEMILUMINESCENCE | FREE-RADICALS | NANOPARTICLES | NANOTHERAPEUTICS | REDUCE COLITIS | REACTIVE OXYGEN METABOLITES | EXPRESSION | COLONIC-MUCOSA | Reactive Oxygen Species - metabolism | Antioxidants - chemistry | Free Radical Scavengers - chemistry | Nanocapsules - administration & dosage | Cyclic N-Oxides - administration & dosage | Spin Labels | Inflammatory Bowel Diseases - metabolism | Nanocapsules - chemistry | Superoxide Dismutase - administration & dosage | Inflammatory Bowel Diseases - pathology | Biomimetic Materials - administration & dosage | Anti-Inflammatory Agents - administration & dosage | Female | Biomimetic Materials - chemistry | Molecular Targeted Therapy - methods | Inflammatory Bowel Diseases - drug therapy | Mice, Inbred C57BL | Free Radical Scavengers - administration & dosage | Treatment Outcome | Superoxide Dismutase - chemistry | Catalase - administration & dosage | Cyclic N-Oxides - chemistry | Animals | Anti-Inflammatory Agents - chemistry | Antioxidants - administration & dosage | Mice | Catalase - chemistry | Hydrolysis | Medical colleges | Hydrogen peroxide | Pharmacy | Analysis | Drugstores | Development and progression | Cyclodextrins | Superoxide | Ulcerative colitis | Drugs | Drug delivery systems | Vehicles | Free radicals | Effectiveness | Catalase | Superoxide dismutase | Nanostructure | Colon | Disease control
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 38, pp. 22 - 35
Abstract Nanodiamond application in biotechnological and medical fields is nowadays in continuous progress. In fact, biocompatibility, reduced dimensions and... 
Advanced Basic Science | Dentistry | Antineoplastic properties | Nanodiamonds | Ciproten (5,7-dimethoxycoumarin) | Quercetin (3,3′,4′,5,6-pentahydroxyflavone) | Therapeutic approach | Natural bioactive compounds | Quercetin (3,3',4',5,6-pentahydroxyflavone) | MATERIALS SCIENCE, BIOMATERIALS | EXOCYTOSIS | INDUCED APOPTOSIS | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | CELL-CYCLE ARREST | ANTIOXIDANT PROPERTIES | Quercetin (3,3 ',4 ',5,6-pentahydroxyflavone) | QUERCETIN | DETONATION NANODIAMOND | DIAMOND NANOPARTICLES | Plant Extracts - chemistry | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Nanocomposites - chemistry | Apoptosis - drug effects | Nanocapsules - administration & dosage | Humans | Drug Carriers - administration & dosage | Coumarins - chemistry | Nanocapsules - chemistry | Nanocapsules - ultrastructure | Neoplasms, Experimental - pathology | Plant Extracts - administration & dosage | Surface Properties | Quercetin - administration & dosage | Nanocomposites - ultrastructure | Diffusion | Cell Survival - drug effects | Nanodiamonds - ultrastructure | Quercetin - chemistry | Nanodiamonds - administration & dosage | Nanodiamonds - chemistry | Coumarins - administration & dosage | Materials Testing | Treatment Outcome | Particle Size | Animals | Mice | HeLa Cells | Neoplasms, Experimental - drug therapy | Nanocomposites - administration & dosage | Antimitotic agents | Care and treatment | Antineoplastic agents | Health aspects | Plant metabolites | Cancer | Cellular | Antiproliferatives | Metabolites | Biocompatibility | Plants (organisms) | Medical | Nanostructure | Conjugation
Journal Article
Biomaterials, ISSN 0142-9612, 2014, Volume 35, Issue 23, pp. 6118 - 6129
Abstract Despite progress, combination therapy of different functional drugs to increase the efficiency of anticancer treatment still remains challenges. An... 
Advanced Basic Science | Dentistry | Chemotherapy | Controlled drug release | Nanoparticle | Polypeptide | Drug co-delivery | DIBLOCK COPOLYMERS | MATERIALS SCIENCE, BIOMATERIALS | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | NANOCARRIERS | MICELLES | COMBINATION | DOCETAXEL | NANOPARTICLES | THERAPY | METASTATIC BREAST-CANCER | Lung Neoplasms - drug therapy | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Nanocomposites - chemistry | Antineoplastic Combined Chemotherapy Protocols - chemistry | Nanocapsules - administration & dosage | Delayed-Action Preparations - chemistry | Lung Neoplasms - pathology | Male | Polyethylene Glycols - chemistry | Doxorubicin - chemistry | Nanocapsules - chemistry | Delayed-Action Preparations - administration & dosage | Pharmaceutical Vehicles - chemical synthesis | Paclitaxel - chemistry | Diffusion | Paclitaxel - administration & dosage | Doxorubicin - administration & dosage | Carcinoma, Non-Small-Cell Lung - pathology | Peptides - chemistry | Treatment Outcome | Animals | Mice, Nude | Mice, Inbred BALB C | Carcinoma, Non-Small-Cell Lung - drug therapy | Nanocomposites - administration & dosage | Medical colleges | Ethylene glycol | Care and treatment | Anthracyclines | Fluorescence | Amino acids | Lung cancer, Non-small cell | Glutamate | Cobalt | Deoxycholic acid | Nanoparticles | Drugs | Surgical implants | Therapy | Nanostructure | Doxorubicin | Tumors | Cancer
Journal Article
Biomaterials, ISSN 0142-9612, 2017, Volume 121, pp. 41 - 54
Abstract Undesired physiological instability of nanocarriers and premature drug leakage during blood circulation result in compromised therapeutic efficacy and... 
Advanced Basic Science | Dentistry | Diselenide bonds | Visible light | Crosslinking | Redox responsiveness | Combination chemotherapy | POLYPRODRUG AMPHIPHILES | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | DOXORUBICIN COMBINATIONS | BLOCK-COPOLYMER MICELLES | TRIGGERED RELEASE | LINKED POLYMERIC MICELLES | DYNAMIC COVALENT BONDS | POLYION COMPLEX VESICLES | SINGLE DISELENIDE | BIOMEDICAL APPLICATIONS | ANTITUMOR EFFICACY | Cross-Linking Reagents - radiation effects | Cell Survival - drug effects | Delayed-Action Preparations - radiation effects | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Camptothecin - chemistry | Cross-Linking Reagents - chemistry | Nanocapsules - administration & dosage | Drug Stability | Humans | Oxidation-Reduction - radiation effects | Delayed-Action Preparations - chemistry | Treatment Outcome | Doxorubicin - chemistry | Nanocapsules - chemistry | Delayed-Action Preparations - administration & dosage | Neoplasms, Experimental - pathology | MCF-7 Cells | Selenium Compounds - administration & dosage | Light | Camptothecin - administration & dosage | Selenium Compounds - chemistry | Nanocapsules - radiation effects | Neoplasms, Experimental - drug therapy | Doxorubicin - administration & dosage | Drugs | Physiological aspects | Anthracyclines | Crosslinked polymers | Chemotherapy | Cancer
Journal Article
Nanoscale, ISSN 2040-3372, 2015, Volume 7, Issue 13, pp. 5859 - 5868
Journal Article
Acta biomaterialia, ISSN 1742-7061, 2017, Volume 53, pp. 355 - 366
[Display omitted] Paclitaxel (PTX) conjugated trimethyl chitosan (TMC-PTX) and folic acid (FA) modified TMC-PTX (FA-TMC-PTX) were developed as polymer-drug... 
Polymer-drug conjugate | Intravenous injection | Antitumor efficacy | Trimethyl chitosan | Paclitaxel | Oral administration | MATERIALS SCIENCE, BIOMATERIALS | ACID | PERMEABILITY | DRUG-DELIVERY | ENGINEERING, BIOMEDICAL | NANOPARTICLES | PRODRUGS | ENHANCEMENT | ABSORPTION | DERIVATIVES | CACO-2 CELLS | Injections, Intravenous | Nanocapsules - administration & dosage | Folic Acid - administration & dosage | Nanocapsules - chemistry | Nanocapsules - ultrastructure | Neoplasms, Experimental - pathology | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Delayed-Action Preparations - chemical synthesis | Female | Diffusion | Paclitaxel - administration & dosage | Antineoplastic Agents, Phytogenic - pharmacokinetics | Molecular Targeted Therapy - methods | Nanoconjugates - ultrastructure | Administration, Oral | Rats | Antineoplastic Agents, Phytogenic - chemistry | Treatment Outcome | Folate Receptors, GPI-Anchored - metabolism | Nanoconjugates - administration & dosage | Folic Acid - pharmacokinetics | Rats, Sprague-Dawley | Animals | Chitosan - chemistry | Mice | Neoplasms, Experimental - metabolism | Neoplasms, Experimental - drug therapy | Nanoconjugates - chemistry | Hydrogen-Ion Concentration | Antimitotic agents | Antineoplastic agents | Phosphates | Adsorption | Analysis | Albumin | Nuclear magnetic resonance spectroscopy | Permeability | High performance liquid chromatography | Folic acid
Journal Article
Biomaterials, ISSN 0142-9612, 2015, Volume 61, pp. 10 - 25
...) alongside conventional cytotoxic drugs has gained great attention owing to increased anti-tumor efficacy over single regimen administrations [7,8] . Due to its high... 
Advanced Basic Science | Dentistry | Co-delivery | siRNA | Synergistic effect | Redox-sensitive | Micelles | Paclitaxel | SiRNA | SYSTEMIC DELIVERY | MATERIALS SCIENCE, BIOMATERIALS | ENGINEERING, BIOMEDICAL | G-PEI MICELLES | ANTICANCER DRUG | POLYMERIC MICELLES | HYALURONIC-ACID | CELLULAR UPTAKE | NANOPARTICLES | GENE | AURORA KINASES | INTRACELLULAR DELIVERY | RNA, Small Interfering - genetics | Nanocapsules - administration & dosage | Humans | Cell Survival - genetics | Nanocapsules - chemistry | Delayed-Action Preparations - administration & dosage | Breast Neoplasms - therapy | RNA, Small Interfering - chemistry | Paclitaxel - chemistry | Antineoplastic Agents, Phytogenic - administration & dosage | Delayed-Action Preparations - chemical synthesis | Diffusion | Paclitaxel - administration & dosage | Aurora Kinase A - genetics | Cell Survival - drug effects | Oxidation-Reduction | Antineoplastic Agents, Phytogenic - chemistry | Treatment Outcome | Nanoconjugates - administration & dosage | Animals | Breast Neoplasms - genetics | Breast Neoplasms - pathology | Cell Line, Tumor | Hydrophobic and Hydrophilic Interactions | Mice | Mice, Inbred BALB C | RNA, Small Interfering - administration & dosage | Drug Combinations | Nanoconjugates - chemistry | Genetic Therapy - methods | Care and treatment | Breast cancer | Drug therapy | Hyaluronic acid | Analysis | Cancer | Drugs | Surgical implants | Biomedical materials | Effectiveness | Breast | Transport
Journal Article
Biomaterials, ISSN 0142-9612, 2017, Volume 117, pp. 92 - 104
Journal Article
Biomaterials, ISSN 0142-9612, 2017, Volume 125, pp. 23 - 37
Abstract Based on the intrinsic features of high stability and unique multifunctionality, inorganic nanoparticles have shown remarkable potentials in combating... 
Advanced Basic Science | Dentistry | Drug delivery | Hollow | Biodegradability | Cancer therapy | Mesoporous organosilica | MATERIALS SCIENCE, BIOMATERIALS | ORGANIC GROUPS | PHOTODYNAMIC THERAPY | ENGINEERING, BIOMEDICAL | SILICA NANOCOMPOSITE NANOPARTICLES | CONTROLLED-RELEASE | CONTROLLED DRUG-DELIVERY | POLYMERIC MICELLES | CANCER-THERAPY | PROTEIN CORONA | MAGNETIC-RESONANCE | BIOMEDICAL APPLICATIONS | Silicon Dioxide - administration & dosage | Nanocomposites - chemistry | Nanocapsules - administration & dosage | Delayed-Action Preparations - chemistry | Doxorubicin - chemistry | Nanocapsules - chemistry | Nanocapsules - ultrastructure | Delayed-Action Preparations - administration & dosage | Neoplasms, Experimental - pathology | Female | Nanocomposites - ultrastructure | Diffusion | Doxorubicin - administration & dosage | Drug Compounding - methods | Silicon Dioxide - chemistry | Treatment Outcome | Absorbable Implants | Particle Size | Animals | Mice, Nude | Neoplasms, Experimental - chemistry | Cell Line, Tumor | Mice | Mice, Inbred BALB C | Porosity | Nanopores - ultrastructure | Neoplasms, Experimental - drug therapy | Nanocomposites - administration & dosage | Biodegradation | Chemotherapy | Silica | Cancer | Biomedical engineering | Tumors | Drugs | Drug delivery systems | Ceramics | Ceramic materials | Vehicles
Journal Article