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Biochimica et Biophysica Acta - Biomembranes, ISSN 0005-2736, 04/2019, Volume 1861, Issue 4, pp. 787 - 797
CEACAM1, a homotypic transmembrane receptor with 12 or 72 amino acid cytosolic domain isoforms, is converted from inactive cis-dimers to active trans-dimers by... 
CEACAM1 | NMR | Phosphorylation | Lipid nanodisc | Calmodulin
Journal Article
FEBS Letters, ISSN 0014-5793, 07/2018, Volume 592, Issue 13, pp. 2282 - 2288
Cytochrome P450 17A1 (CYP17A1) catalyzes the synthesis of androgens from the steroid precursors pregnenolone and progesterone in a two-step reaction process:... 
Nanodisc | cytochrome b5 | cytochrome P450 | androgen biosynthesis
Journal Article
Molecular Cell, ISSN 1097-2765, 03/2018, Volume 69, Issue 6, pp. 993 - 1004.e3
The molecular mechanism of transmembrane proton translocation in rotary motor ATPases is not fully understood. Here, we report the 3.5-Å resolution cryoEM... 
Voa1 | reversible disassembly | cryoEM | proton pumping | vacuolar H+-ATPase | Vo proton channel | lipid nanodisc | membrane protein structure | V-ATPase assembly | proton channel | ATPase | vacuolar H | Index Medicus | Vo proton channelcryo | EMlipid nanodisc | BASIC BIOLOGICAL SCIENCES | Vacuolar H+-ATPase
Journal Article
Structure, ISSN 0969-2126, 10/2018, Volume 26, Issue 10, pp. 1303 - 1313.e4
Understanding gating principles of ion channels at high resolution is of great importance. Here we investigate the conformational transition from closed to... 
ryanodine receptor | ion channel gating | cryo-EM | lipid mimetic | calcium signaling | lipid nanodiscs | ACTIVATION | CA2+ RELEASE | BIOCHEMISTRY & MOLECULAR BIOLOGY | MECHANISMS | SARCOPLASMIC-RETICULUM | CELL BIOLOGY | CALCIUM-RELEASE CHANNEL | BIOPHYSICS | STRUCTURAL BASIS | PURIFICATION | MEMBRANE-PROTEINS | RECONSTITUTION | INSIGHTS | Physiological aspects | Membrane lipids | Protein binding
Journal Article
Nanotechnology, ISSN 0957-4484, 04/2018, Volume 29, Issue 25, pp. 255502 - 255502
In this work we report on plasma oxidation of palladium (Pd) to form reliable palladium/palladium oxide (Pd/PdO x ) core-shell sensor for ppb level H2S... 
colloidal lithography | nanodiscs | plasma oxidation
Journal Article
FEBS Letters, ISSN 0014-5793, 07/2018, Volume 592, Issue 13, pp. 2282 - 2288
Cytochrome P450 17A1 ( CYP 17A1) catalyzes the synthesis of androgens from the steroid precursors pregnenolone and progesterone in a two‐step reaction process:... 
Nanodisc | cytochrome b5 | cytochrome P450 | androgen biosynthesis | Index Medicus
Journal Article
Angewandte Chemie (International ed. in English), ISSN 1433-7851, 1/2018, Volume 57, Issue 5, pp. 1342 - 1345
Polymer lipid nanodiscs have provided an invaluable system for structural and functional studies of membrane proteins in their near-native environment. In... 
magnetic-alignment | SMA | pH tolerance | lipid bilayer | polymer nanodisc
Journal Article
Journal Article
Biochemical and Biophysical Research Communications, ISSN 0006-291X, 05/2017, Volume 487, Issue 2, pp. 351 - 355
KRas4b is a small G-protein whose constitutively active oncogenic mutants are present in 90% of pancreatic cancers. Using fully post-translationally modified... 
Nanodisc | Lipid specificity | KRas4b | Cancer signaling | PIP2 | PHOSPHOLIPID-BILAYER NANODISCS | MOLECULAR-DYNAMICS | ACTIVATION | RAS | BIOCHEMISTRY & MOLECULAR BIOLOGY | MIMETIC MODEL | METHYLATED KRAS4B | BIOPHYSICS | STRUCTURAL BASIS | PROTEINS | Index Medicus
Journal Article
BBA - Biomembranes, ISSN 0005-2736, 04/2019, Volume 1861, Issue 4, pp. 787 - 797
CEACAM1, a homotypic transmembrane receptor with 12 or 72 amino acid cytosolic domain isoforms, is converted from inactive -dimers to active -dimers by... 
CEACAM1 | Phosphorylation | NMR | Lipid nanodisc | Calmodulin | C-CAM | CYTOPLASMIC DOMAIN | PHOSPHOLIPID-BILAYER NANODISCS | ACTIN | MOLECULE | BIOCHEMISTRY & MOLECULAR BIOLOGY | CELL-ADHESION | MICELLES | BIOPHYSICS | ACCURATE DOCKING | CALMODULIN-BINDING | PROTEINS
Journal Article
Proceedings of the National Academy of Sciences of the United States of America, ISSN 0027-8424, 12/2018, Volume 115, Issue 50, pp. 12751 - 12756
Journal Article
Journal of Molecular Biology, ISSN 0022-2836, 10/2018, Volume 430, Issue 21, pp. 4230 - 4244
Journal Article
Annual Review of Biophysics, ISSN 1936-122X, 5/2018, Volume 47, Issue 1, pp. 107 - 124
The study of membrane proteins and receptors presents many challenges to researchers wishing to perform biophysical measurements to determine the structure,... 
Nanodisc | membrane protein | cancer signaling | integrin activation | blood coagulation | fluorescence | Membrane proteins | Integrins
Journal Article
Biochimica et Biophysica Acta - Biomembranes, ISSN 0005-2736, 2015, Volume 1848, Issue 5, pp. 1224 - 1233
Membrane proteins (MPs) are prevalent drug discovery targets involved in many cell processes. Despite their high potential as drug targets, the study of MPs... 
Surface plasmon resonance | Scintillation proximity assay | Kinetics | GPCRs | Nanodiscs
Journal Article
Bulletin of the Korean Chemical Society, ISSN 1229-5949, 07/2019, Volume 40, Issue 7, pp. 680 - 685
G‐protein coupled receptors (GPCRs) comprise the largest membrane protein family and are involved in various kinds of physiological phenomena. LPA 1 belongs to... 
Agonist | scAb | scFv | GPCR | LPA | Nanodiscs
Journal Article
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