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Biomacromolecules, ISSN 1525-7797, 05/2014, Volume 15, Issue 5, pp. 1768 - 1776
We have developed herein an engineered polymer-based nanoplatform showing the convergence of two-photon fluorescence imaging and bimodal phototherapeutic... 
POLYMER SCIENCE | EQUILIBRIUM-CONSTANTS | NITRIC-OXIDE RELEASE | DRUG-DELIVERY | BIOCHEMISTRY & MOLECULAR BIOLOGY | CHEMISTRY, ORGANIC | BLOCK-COPOLYMER MICELLES | ZINC PHTHALOCYANINE | THERAPY | BETA-CYCLODEXTRIN POLYMER | MULTIWAVELENGTH SPECTROSCOPIC DATA | INCLUSION COMPLEX | WATER | Polymers - administration & dosage | Photosensitizing Agents - chemistry | Skin Neoplasms - drug therapy | Nanoparticles - chemistry | Antineoplastic Agents - chemical synthesis | Biocompatible Materials - chemistry | Carcinoma, Squamous Cell - pathology | Humans | Drug Carriers - administration & dosage | Antineoplastic Agents - administration & dosage | Drug Carriers - chemistry | Indoles - administration & dosage | Biocompatible Materials - chemical synthesis | Photosensitizing Agents - administration & dosage | Drug Carriers - radiation effects | Singlet Oxygen - metabolism | Nanoparticles - radiation effects | Photosensitizing Agents - pharmacology | Polymers - radiation effects | Antineoplastic Agents - pharmacology | Molecular Structure | Epichlorohydrin - administration & dosage | Photosensitizing Agents - chemical synthesis | Skin Neoplasms - pathology | Cell Survival - drug effects | Nitric Oxide - chemistry | Polymers - chemical synthesis | Photons | Antineoplastic Agents - chemistry | Epichlorohydrin - chemistry | Carcinoma, Squamous Cell - drug therapy | beta-Cyclodextrins - administration & dosage | beta-Cyclodextrins - chemistry | Biocompatible Materials - radiation effects | Singlet Oxygen - chemistry | Cell Line, Tumor | Organometallic Compounds - chemistry | Polymers - chemistry | Biocompatible Materials - administration & dosage | Cell Proliferation - drug effects | Nanoparticles - administration & dosage | Nitric Oxide - metabolism | Indoles - chemistry | Microscopy, Fluorescence | Drug Screening Assays, Antitumor | Organometallic Compounds - administration & dosage | Index Medicus | Materials Chemistry | Biofysik | Fysikalisk kemi | Biophysics | Physical Chemistry | Materialkemi
Journal Article
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 04/2019, Volume 560, pp. 19 - 26
Journal Article
Vaccine, ISSN 0264-410X, 05/2018, Volume 36, Issue 20, pp. 2886 - 2895
In this study, the potential of N-trimethyl chitosan (TMC) nanoparticles as a carrier system for the nasal delivery of the r4M2e.HSP70c, as an M2e-based... 
N-trimethyl chitosan (TMC) | M2e | Vaccine | HSP70 | Intranasal | Influenza | MEDICINE, RESEARCH & EXPERIMENTAL | IMMUNE-RESPONSE | DRUG-DELIVERY | EXTRACELLULAR DOMAIN | MUCOSAL | INDUCTION | IMMUNOLOGY | M2 PROTEIN | INFLUENZA-A VIRUS | UNIVERSAL VACCINE | FUSION PROTEIN | INTRANASAL IMMUNIZATION | Influenza Vaccines - administration & dosage | Adjuvants, Immunologic - administration & dosage | Adjuvants, Immunologic - pharmacology | Cell Proliferation | Humans | Bronchoalveolar Lavage Fluid - immunology | Drug Carriers - administration & dosage | Vaccines, Synthetic - immunology | HSP72 Heat-Shock Proteins - pharmacology | Serum - immunology | Immunity, Humoral | Antibodies, Viral - analysis | Leukocytes, Mononuclear - immunology | Female | Immunoglobulin G - analysis | Disease Models, Animal | Chitosan - administration & dosage | Treatment Outcome | Viral Matrix Proteins - administration & dosage | Administration, Intranasal | Interferon-gamma - analysis | Animals | Influenza Vaccines - immunology | HSP72 Heat-Shock Proteins - administration & dosage | Survival Analysis | Mice, Inbred BALB C | Nanoparticles - administration & dosage | Viral Matrix Proteins - immunology | Vaccines, Synthetic - administration & dosage | Immunity, Cellular | Influenza, Human - prevention & control | Immunoglobulin A - analysis | Influenza viruses | Influenza vaccines | Antigens | Medical research | Analysis | Vaccination | Medicine, Experimental | Heat shock proteins | Health aspects | Encapsulation | IgG antibody | Immunoglobulin G | Viruses | Infections | Lymphocytes T | Vaccines | Immunoglobulin A | Immunity | Nanoparticles | Lethal dose | Proteins | Microorganisms | Lymphocytes | Bronchoalveolar lavage | Rodents | Peripheral blood | Influenza A | Alveoli | Recombinant | Immunization | Bronchus | Adjuvants | Intranasal administration | Morbidity | Immune response (humoral) | Immunogenicity | γ-Interferon | Mice | Chitosan | Viral infections | Index Medicus
Journal Article
Journal Article
European Journal of Pharmaceutical Sciences, ISSN 0928-0987, 03/2013, Volume 48, Issue 4-5, pp. 595 - 603
The aim of this study was to develop novel multiple agents loaded poly ( , -lactide-co-glycolide acid) (PLGA) nanoparticles (NPs) and evaluate their potential... 
Nanoparticles | PLGA | Brain delivery | Inner ear administration | NERVOUS-SYSTEM | DRUG-DELIVERY | FOCAL CEREBRAL-ISCHEMIA | GUINEA-PIGS | RAT MODEL | FREE-RADICALS | ISCHEMIA-REPERFUSION INJURY | SALVIANOLIC ACID-B | NITRIC-OXIDE | PHARMACOLOGY & PHARMACY | BLOOD | Ginsenosides - cerebrospinal fluid | Carotid Arteries | Nanoparticles - chemistry | Reperfusion Injury - drug therapy | Drug Carriers - administration & dosage | Benzofurans - administration & dosage | Male | Diterpenes, Abietane - administration & dosage | Diterpenes, Abietane - pharmacokinetics | Drug Carriers - chemistry | Benzofurans - pharmacokinetics | Brain - metabolism | Diterpenes, Abietane - cerebrospinal fluid | Neuroprotective Agents - pharmacokinetics | Benzofurans - cerebrospinal fluid | Ginsenosides - administration & dosage | Neuroprotective Agents - cerebrospinal fluid | Neuroprotective Agents - administration & dosage | Lactic Acid - administration & dosage | Reperfusion Injury - metabolism | Polyglycolic Acid - administration & dosage | Drug Administration Routes | Guinea Pigs | Lactic Acid - chemistry | Ear, Inner | Panax notoginseng | Particle Size | Animals | Polyglycolic Acid - chemistry | Drug Carriers - pharmacokinetics | Nanoparticles - administration & dosage | Ginsenosides - pharmacokinetics | Drugs | Drug delivery systems | Surface active agents | Nitric oxide | Drugstores | Superoxide | Sulfates | Vehicles | Index Medicus
Journal Article
Advanced Functional Materials, ISSN 1616-301X, 02/2018, Volume 28, Issue 9, pp. 1705710 - n/a
Great efforts have been devoted so far to combine nano‐magnetic hyperthermia and nano‐photothermal therapy to achieve encouraging additive therapeutic... 
nanotheranostics | breast cancer | nanomedicine | hyperthermia | molecular imaging | Nanoparticles | Therapy | Blood circulation | Polyethylene glycol | Imaging | Magnetic resonance | Fluorescence | Hyperthermia | Fever | Cytoplasm
Journal Article
Journal of Controlled Release, ISSN 0168-3659, 12/2017, Volume 267, pp. 191 - 202
Combination chemotherapy is commonly used to treat advanced breast cancer. However, treatment success is often limited due to systemic toxicity. To improve... 
Polymer drug conjugates | Synergy | Breast cancer | Drug combinations | Gemcitabine | Doxorubcin | SCHEDULE-DEPENDENT INTERACTION | DRUG | COMBINATION THERAPY | MESOPOROUS SILICA NANOPARTICLES | PHASE-II | ANTITUMOR-ACTIVITY | CHEMISTRY, MULTIDISCIPLINARY | CHEMOTHERAPY | PACLITAXEL | CO-DELIVERY | CISPLATIN | PHARMACOLOGY & PHARMACY | Prodrugs - administration & dosage | Deoxycytidine - chemistry | Antineoplastic Combined Chemotherapy Protocols - administration & dosage | Antineoplastic Combined Chemotherapy Protocols - chemistry | Humans | Drug Carriers - administration & dosage | Doxorubicin - chemistry | Prodrugs - chemistry | Triple Negative Breast Neoplasms - drug therapy | Drug Carriers - chemistry | Antimetabolites, Antineoplastic - administration & dosage | Dose-Response Relationship, Drug | Antibiotics, Antineoplastic - chemistry | Doxorubicin - administration & dosage | Cell Survival - drug effects | Hyaluronic Acid - administration & dosage | Deoxycytidine - administration & dosage | Hyaluronic Acid - chemistry | Antimetabolites, Antineoplastic - chemistry | Antibiotics, Antineoplastic - administration & dosage | Drug Synergism | Animals | Cell Line, Tumor | Drug Liberation | Mice | Mice, Inbred BALB C | Deoxycytidine - analogs & derivatives | Drugs | Anthracyclines | Drug delivery systems | Chemotherapy | Analysis | Polymers | Hyaluronic acid | Vehicles | Cancer | Index Medicus
Journal Article
International Journal of Pharmaceutics, ISSN 0378-5173, 03/2016, Volume 501, Issue 1-2, pp. 271 - 277
Journal Article
Journal Article
Journal of Agricultural and Food Chemistry, ISSN 0021-8561, 10/2018, Volume 66, Issue 40, pp. 10479 - 10489
We present an improved type of food gum (salecan) based hydrogels for oral delivery of insulin. Structural hydrogel formation was assessed with Fourier... 
salecan polysaccharides | hydrogels | oral | drug delivery | insulin | ACID | FOOD SCIENCE & TECHNOLOGY | CONTROLLED DRUG-RELEASE | SEMI-IPN HYDROGELS | CATIONIC DYES | HYBRID HYDROGELS | HIGHLY EFFICIENT REMOVAL | POLYMERIC NANOPARTICLES | AGRICULTURE, MULTIDISCIPLINARY | CHEMISTRY, APPLIED | NANOCOMPOSITE HYDROGELS | POTATO STARCH | Index Medicus
Journal Article
PLoS Neglected Tropical Diseases, ISSN 1935-2727, 11/2012, Volume 6, Issue 11, pp. e1894 - e1894
Journal Article