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European Heart Journal, ISSN 0195-668X, 11/2017, Volume 38, Issue 44, pp. 3282 - 3292
Journal Article
Journal of Thrombosis and Haemostasis, ISSN 1538-7933, 12/2007, Volume 5, Issue 12, pp. 2376 - 2385
Background: Selective inhibitors of cyclooxygenase‐2 (COX‐2) called coxibs, are effective anti‐inflammatory and analgesic drugs. Recently, these drugs were... 
thromboxane | coxibs | thrombin generation | prostacyclin | NSAID | platelet activation | Thrombin generation | Prostacyclin | Platelet activation | Thromboxane | Coxibs | MASS-SPECTROMETRY | CYCLOOXYGENASES | ANTIPLATELET | THROMBOMODULIN | CLOPIDOGREL | PERIPHERAL VASCULAR DISEASE | HEMATOLOGY | EXPRESSION | IONIZATION | TISSUE FACTOR | Humans | Naproxen - pharmacology | Sulfones - adverse effects | Male | Reference Values | Blood Platelets - enzymology | Sulfones - pharmacology | Prostaglandins - blood | Lactones - pharmacology | Phospholipases A - blood | Cyclooxygenase 2 Inhibitors - adverse effects | Sulfonamides - blood | Lactones - blood | Cyclooxygenase 2 - blood | Time Factors | Prostaglandins - urine | Pyrazoles - blood | Antigens, Neoplasm - blood | Adult | Platelet Aggregation - drug effects | Cyclooxygenase 2 Inhibitors - blood | Blood Platelets - drug effects | Sulfones - blood | Pyrazoles - adverse effects | Pyrazoles - pharmacology | Thrombomodulin - blood | Naproxen - adverse effects | Cyclic AMP - blood | Cyclooxygenase 2 Inhibitors - pharmacology | Double-Blind Method | Celecoxib | Lactones - adverse effects | Cell Adhesion - drug effects | Naproxen - blood | Sulfonamides - pharmacology | Thromboxanes - blood | Thromboxanes - urine | Blood Platelets - metabolism | Fibrinogen - metabolism | P-Selectin - blood | Sulfonamides - adverse effects | Leukocytes - drug effects | Platelet Activation - drug effects | Thrombin - metabolism | Platelet Membrane Glycoprotein IIb - blood | Physiological aspects | Prothrombin | COX-2 inhibitors | Thrombin | Analysis
Journal Article
FASEB Journal, ISSN 0892-6638, 03/2006, Volume 20, Issue 3, pp. 542 - 544
It is widely believed that the potencies of nonsteroid anti-inflammatory drugs ( NSAIDs) as inhibitors of cyclooxygenase ( COX) are influenced by protein... 
SITE | MECHANISM | BIOCHEMISTRY & MOLECULAR BIOLOGY | nonsteroid anti-inflammatory drugs | coxibs | PROSTAGLANDIN H-2 SYNTHASE | CELL BIOLOGY | CYCLO-OXYGENASE-2 | THERAPY | FLUID | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | BIOLOGY | prostaglandins | SELECTIVITY | Organic Chemicals - cerebrospinal fluid | Humans | Naproxen - pharmacology | Synovial Fluid - metabolism | Pyrazoles - cerebrospinal fluid | Sodium Salicylate - pharmacology | Lactones - pharmacology | Aspirin - cerebrospinal fluid | Cell Line - drug effects | Calcium - physiology | Pyrazoles - blood | Organic Chemicals - pharmacology | Dinoprostone - cerebrospinal fluid | Diclofenac - cerebrospinal fluid | Aspirin - pharmacology | Sulfones - cerebrospinal fluid | Aspirin - blood | Thiazines - blood | Sulfonamides - pharmacology | Indomethacin - cerebrospinal fluid | Indomethacin - pharmacology | Cyclooxygenase 1 - drug effects | Cyclooxygenase Inhibitors - adverse effects | Cyclooxygenase Inhibitors - blood | Diclofenac - pharmacology | Thiazoles - blood | Thromboxane A2 - blood | Cerebrospinal Fluid Proteins - pharmacology | Dinoprostone - biosynthesis | Lactones - cerebrospinal fluid | Blood Platelets - enzymology | Cyclooxygenase 2 Inhibitors - cerebrospinal fluid | Sodium Salicylate - cerebrospinal fluid | Sulfones - pharmacology | Blood Proteins - pharmacology | Cyclooxygenase 2 Inhibitors - adverse effects | Sulfonamides - blood | Lactones - blood | Naproxen - cerebrospinal fluid | Sodium Salicylate - blood | Thiazines - pharmacology | Cyclooxygenase 2 Inhibitors - blood | Cyclooxygenase Inhibitors - cerebrospinal fluid | Blood Platelets - drug effects | Sulfones - blood | Organic Chemicals - blood | Ionophores - pharmacology | Pyrazoles - pharmacology | Sulfonamides - cerebrospinal fluid | Cyclooxygenase 2 Inhibitors - pharmacology | Thiazoles - cerebrospinal fluid | Celecoxib | Diclofenac - blood | Dinoprostone - blood | Naproxen - blood | Organ Specificity | Calcimycin - pharmacology | Cyclooxygenase Inhibitors - pharmacology | Indomethacin - blood | Protein Binding | Thiazines - cerebrospinal fluid | Thiazoles - pharmacology
Journal Article
Journal Article
Journal Article
Journal of Pharmacology and Experimental Therapeutics, ISSN 0022-3565, 08/2007, Volume 322, Issue 2, pp. 453 - 460
Journal Article
Journal Article
BMC Cardiovascular Disorders, ISSN 1471-2261, 10/2012, Volume 12, Issue 1, p. 93
Background: Nonsteroidal anti-inflammatory drugs (NSAIDs) may disrupt control of blood pressure in hypertensive patients and increase their risk of morbidity,... 
Hypertension | Blood pressure | Propensity score | NSAIDs | CARDIAC & CARDIOVASCULAR SYSTEMS | INDOMETHACIN | RISK | CELECOXIB | HYDROCHLOROTHIAZIDE | IBUPROFEN | CARE PATIENTS | THERAPY | ANALGESIC USE | INHIBITORS | OSTEOARTHRITIS | Ibuprofen - therapeutic use | Pyrazoles - therapeutic use | Indiana | Humans | Middle Aged | Hypertension - drug therapy | Male | Drug Interactions | Analgesics, Non-Narcotic - adverse effects | Female | Blood Pressure - drug effects | Retrospective Studies | Acetaminophen - therapeutic use | Hypertension - diagnosis | Odds Ratio | Risk Assessment | Risk Factors | Linear Models | Treatment Outcome | Analgesics, Non-Narcotic - therapeutic use | Celecoxib | Antihypertensive Agents - therapeutic use | Naproxen - therapeutic use | Hypertension - physiopathology | Propensity Score | Anti-Inflammatory Agents, Non-Steroidal - adverse effects | Sulfonamides - therapeutic use | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Measurement | Medical research | Care and treatment | Usage | Calcium channels | Mortality | Medical records | Enzyme inhibitors | Acetaminophen | Angiotensin converting enzyme | Ibuprofen | Medicine, Experimental | Diuretics | Antihypertensive drugs | Nonsteroidal anti-inflammatory drugs | Comparative analysis | Health aspects | Studies | Cardiovascular disease | Drug therapy
Journal Article
by Baigent, Colin and Bhala, N and Emberson, J and Merhi, A and Abramson, S and Arber, N and Baron, J.A and Bombardier, C and Cannon, C and Farkouh, M.E and FitzGerald, G.A and Goss, P and Halls, H and Hawk, E and Hawkey, C and Hennekens, C and Hochberg, M and Holland, L.E and Kearney, P.M and Laine, L and Lanas, A and Lance, P and Laupacis, A and Oates, J and Patrono, C and Schnitzer, T.J and Solomon, S and Tugwell, P and Wilson, K and Wittes, J and Adelowo, O and Aisen, P and Al-Quorain, A and Altman, R and Bakris, G and Baumgartner, H and Bresee, C and Carducci, M and Chang, D.-M and Chou, C.-T and Clegg, D and Cudkowicz, M and Doody, L and Miedany, Y.El and Falandry, C and Farley, J and Ford, L and Garcia-Losa, M and Gonzalez-Ortiz, M and Haghighi, M and Hala, M and Iwama, T and Jajic, Z and Kerr, D and Kim, H.-S and Kohne, C and Koo, B.-K and Martin, B and Meinert, C and Muller, N and Myklebust, G and Neustadt, D and Omdal, R and Ozgocmen, S and Papas, A and Patrignani, P and Pelliccia, F and Roy, V and Schlegelmilch, I and Umar, A and Wahlstrom, O and Wollheim, F and Yocum, S and Zhang, X.Y and Hall, E and McGettigan, P and Midgley, R and Moore, R.A and Philipson, R and Curtis, S and Reicin, A and Bond, J and Moore, A and Essex, M and Fabule, J and Morrison, B and Tive, L and Bhala, N and Davies, K and Emberson, J and Halls, H and Holland, L.E and Kearney, P.M and Merhi, A and Patrono, C and Wilson, K and Yau, F and Coxib Traditional NSAID Trialists and Coxib and traditional NSAID Trialists' (CNT) Collaboration
Lancet, The, ISSN 0140-6736, 2013, Volume 382, Issue 9894, pp. 769 - 779
Journal Article