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1. Full Text Nasal IL-4+ CXCR5+ CD4+ T follicular helper cell counts correlate with local IgE production in eosinophilic nasal polyps
by Zhang, Ya-Na, MD, PhD and Song, Jia, MD and Wang, Hai, MD and Wang, Heng, MD, PhD and Zeng, Ming, MD, PhD and Zhai, Guan-Ting, MD and Ma, Jin, MD and Li, Zhi-Yong, MD and Liao, Bo, MD and Wang, Bao-Feng, MD and Zhen, Zhen, MD, PhD and Wang, Nan, MD, PhD and Cao, Ping-Ping, MD, PhD and Lin, Peng, MD and Ning, Qin, MD, PhD and Liu, Zheng, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 137, Issue 2, pp. 462 - 473
Allergy and Immunology | B cell | IgE | IL-4 | eosinophil | ectopic lymphoid structure | nasal polyp | T follicular helper cell | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | T-Lymphocyte Subsets - immunology | Eosinophilia - metabolism | Humans | Immunoglobulin E - biosynthesis | Nasal Mucosa - pathology | Nasal Polyps - diagnosis | Eosinophilia - pathology | Immunoglobulin E - immunology | T-Lymphocytes, Helper-Inducer - immunology | Nasal Mucosa - metabolism | Nasal Polyps - metabolism | B-Lymphocytes - metabolism | Nasal Polyps - immunology | Antibody Formation - immunology | Nasal Polyps - pathology | Receptors, CXCR5 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Interleukin-4 - metabolism | Immunophenotyping | Phenotype | B-Lymphocytes - immunology | Eosinophilia - immunology | Nasal Mucosa - immunology | T-Lymphocyte Subsets - metabolism | Biomarkers | Lymphocyte Count | Proteins | Immunoglobulins | Cytokines | Lymphocytes | Rodents | T cell receptors | Inflammation | Patients | Index Medicus | Abridged Index Medicus
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2. Full Text IL-25 as a novel therapeutic target in nasal polyps of patients with chronic rhinosinusitis
by Shin, Hyun-Woo, MD, PhD and Kim, Dong-Kyu, MD and Park, Min-Hyun, MD, PhD and Eun, Kyoung Mi, BSc and Lee, Mingyu, BSc and So, Daeho, BSc and Kong, Il Gyu, MD, PhD and Mo, Ji-Hun, MD, PhD and Yang, Min-Suk, MD and Jin, Hong Ryul, MD, PhD and Park, Jong-Wan, MD, PhD and Kim, Dae Woo, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 135, Issue 6, pp. 1476 - 1485.e7
Allergy and Immunology | sinusitis | allergy | animal models | IL-25 | Nasal polyp | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Eosinophil Cationic Protein - genetics | Eosinophils - drug effects | Humans | Middle Aged | Male | Receptors, Interleukin-17 - genetics | Eosinophils - immunology | Rhinitis - drug therapy | Eosinophil Cationic Protein - immunology | Transforming Growth Factor beta2 - immunology | Sinusitis - genetics | Gene Expression - immunology | Eosinophils - pathology | Disease Models, Animal | Nuclear Receptor Subfamily 1, Group F, Member 3 - immunology | Antibodies, Monoclonal - pharmacology | Neutrophils - drug effects | Interleukin-17 - genetics | Rhinitis - complications | Mice | Chronic Disease | Sinusitis - drug therapy | GATA3 Transcription Factor - genetics | Cell Adhesion Molecules - genetics | Gene Expression - drug effects | GATA3 Transcription Factor - immunology | Receptors, Interleukin-17 - immunology | Interleukin-17 - immunology | T-Box Domain Proteins - immunology | Cell Adhesion Molecules - immunology | Case-Control Studies | Sinusitis - complications | Transforming Growth Factor beta1 - immunology | Sinusitis - immunology | Nasal Polyps - genetics | Adult | Female | Nuclear Receptor Subfamily 1, Group F, Member 3 - genetics | Neutrophils - pathology | Nasal Polyps - immunology | Rhinitis - immunology | Neutrophils - immunology | Transforming Growth Factor beta1 - genetics | Nasal Polyps - drug therapy | T-Box Domain Proteins - genetics | Rhinitis - genetics | Animals | Nasal Polyps - complications | Interleukin-17 - antagonists & inhibitors | Transforming Growth Factor beta2 - genetics | Medical colleges | Nurse practitioners | Nasal polyps | Atopic dermatitis | Health aspects | Proteins | Immunoglobulins | Pulmonary fibrosis | Disease | Laboratories | Rodents | Surgery | Family medical history | Endoscopy | Quality of life | Index Medicus | Abridged Index Medicus
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3. Full Text IL-25/IL-33–responsive TH2 cells characterize nasal polyps with a default TH17 signature in nasal mucosa
by Lam, Emily P.S and Kariyawasam, Harsha H and Rana, Batika M.J and Durham, Stephen R and McKenzie, Andrew N.J and Powell, Nicholas and Orban, Nara and Lennartz-Walker, Melissa and Hopkins, Claire and Ying, Sun and Rimmer, Joanne and Lund, Valerie J and Cousins, David J and Till, Stephen J
Journal of allergy and clinical immunology, ISSN 0091-6749, 05/2016, Volume 137, Issue 5, pp. 1514 - 1524
ST2 | TH2 cells | microarray | Chronic rhinosinusitis with nasal polyps | IL-17RB | nasal mucosa | TH17 cells | IL-25 | T-cell phenotype | IL-33 | T-cell receptor Vβ repertoire | 2 cells | 17 cells | Nasal Polyps - immunology | Rhinitis - immunology | Eosinophilia - immunology | Nasal Mucosa - immunology | Sinusitis - immunology | Humans | Interleukin-17 - immunology | Th17 Cells - immunology | Th2 Cells - immunology | Chronic Disease | Interleukin-33 - immunology | Studies | Cell culture | Genotype & phenotype | Cytokines | Lymphocytes | Cloning | T cell receptors | Gene expression | Index Medicus | Abridged Index Medicus | CRTH2, Chemoattractant receptor-homologous molecule expressed on TH2 cells | CDR3, Complementarity-determining region 3 | ILC2, Type 2 innate lymphoid cell | AIM2, Absent in melanoma 2 | TCR Vβ, T-cell receptor variable β-chain | CRSwNP, Chronic rhinosinusitis with nasal polyposis | Mechanisms of Allergy and Clinical Immunology
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4. Full Text Chronic Rhinosinusitis with Nasal Polyps
by Stevens, Whitney W., MD, PhD and Schleimer, Robert P., PhD and Kern, Robert C., MD
The journal of allergy and clinical immunology in practice (Cambridge, MA), ISSN 2213-2198, 2016, Volume 4, Issue 4, pp. 565 - 572
Internal Medicine | Allergy and Immunology | Chronic rhinosinusitis with nasal polyps | Nasal polyp | Chronic rhinosinusitis | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Nasal Polyps - immunology | Rhinitis - immunology | Comorbidity | Sinusitis - diagnosis | Humans | Rhinitis - diagnosis | Nasal Polyps - diagnosis | Sinusitis - epidemiology | Rhinitis - genetics | Sinusitis - genetics | Sinusitis - immunology | Nasal Polyps - genetics | Biomarkers | Nasal Polyps - epidemiology | Rhinitis - epidemiology | Chronic Disease | Physicians | Pathogenesis | Cystic fibrosis | Inflammation | Research | Health education | Allergies | Asthma | Studies | Copyright | Sinuses | Nose | Surgery | Accreditation | Age | Tumors | Index Medicus
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5. Full Text Group 2 innate lymphoid cells (ILC2s) are increased in chronic rhinosinusitis with nasal polyps or eosinophilia
by Ho, J and Bailey, M and Zaunders, J and Mrad, N and Sacks, R and Sewell, W and Harvey, R. J
Clinical and experimental allergy, ISSN 0954-7894, 02/2015, Volume 45, Issue 2, pp. 394 - 403
ILC2 | group 2 innate lymphoid cell | chronic rhinosinusitis | eosinophils | tissue | human | nasal polyp | Group 2 innate lymphoid cell | Human | Tissue | Chronic rhinosinusitis | Nasal polyp | Eosinophils | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Humans | Middle Aged | Hypersensitivity - immunology | Male | Nasal Mucosa - pathology | Case-Control Studies | Immunoglobulin E - blood | Lymphocyte Subsets - immunology | Sinusitis - complications | Young Adult | Lymphocyte Subsets - metabolism | Immunoglobulin E - immunology | Sinusitis - immunology | Antigens, Surface - metabolism | Adult | Female | Leukocyte Count | Neutrophil Infiltration - immunology | Nasal Polyps - immunology | Rhinitis - immunology | Immunophenotyping | Patient Outcome Assessment | Immunity, Innate | Nasal Polyps - complications | Eosinophilia - immunology | Nasal Mucosa - immunology | Rhinitis - complications | Aged | Eosinophilia - complications | Chronic Disease | Immunoglobulin E | Nasal polyps | Eosinophilia | Index Medicus
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6. Full Text Association of periostin expression with eosinophilic inflammation in nasal polyps
by Wang, Min, PhD and Wang, Xiangdong, MD, PhD and Zhang, Nan, MD, PhD and Wang, Hong, BS and Li, Ying, BS and Fan, Erzhong, BS and Zhang, Liang, MS and Zhang, Luo, MD, PhD and Bachert, Claus, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2015, Volume 136, Issue 6, pp. 1700 - 1703.e9
Allergy and Immunology | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Sinusitis - blood | Cell Adhesion Molecules - genetics | Tenascin - genetics | Humans | Middle Aged | Tenascin - immunology | Male | Cell Adhesion Molecules - immunology | Eosinophil Cationic Protein - immunology | Young Adult | Sinusitis - immunology | Adult | Female | Cytokines - immunology | Cell Adhesion Molecules - blood | Nasal Polyps - immunology | Rhinitis - immunology | Fibronectins - immunology | Inflammation - immunology | Eosinophilia - immunology | Adolescent | Aged | Chemokine CCL11 - immunology | Rhinitis - blood | Nasal Polyps - blood | Medical colleges | Proteins | Studies | Cytokines | Asthma | Index Medicus | Abridged Index Medicus | Medicin och hälsovetenskap
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7. Full Text IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps
by Shaw, Joanne L and Fakhri, Samer and Citardi, Martin J and Porter, Paul C and Corry, David B and Kheradmand, Farrah and Liu, Yong-Jun and Luong, Amber
American journal of respiratory and critical care medicine, ISSN 1073-449X, 08/2013, Volume 188, Issue 4, pp. 432 - 439
Innate lymphoid cells | Alternaria alternata | Aspergillus fumigatus | Epithelial cells | IL-33 | Respiratory System | Life Sciences & Biomedicine | Critical Care Medicine | General & Internal Medicine | Science & Technology | Otorhinolaryngology. Stomatology | Non tumoral diseases | Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy | Biological and medical sciences | Intensive care medicine | Medical sciences | Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology | Tumors | Pneumology | Epithelial Cells - metabolism | Humans | Middle Aged | Rhinitis - physiopathology | Male | Th2 Cells - immunology | Interleukins - metabolism | Sinusitis - complications | Flow Cytometry | Interleukins - physiology | Immunity, Innate - physiology | Sinusitis - immunology | Aged, 80 and over | Sinusitis - physiopathology | Adult | Female | Nasal Polyps - metabolism | Rhinitis - immunology | Sinusitis - metabolism | Interleukin-33 | Th2 Cells - metabolism | Mucous Membrane - metabolism | Rhinitis - metabolism | Rhinitis - complications | Aged | Chronic Disease | Index Medicus | Abridged Index Medicus | epithelial cells | innate lymphoid cells
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8. Full Text Omalizumab is effective in allergic and nonallergic patients with nasal polyps and asthma
by Gevaert, Philippe, MD, PhD and Calus, Lien, MD and Van Zele, Thibaut, MD, PhD and Blomme, Katrien, MSc and De Ruyck, Natalie, MSc and Bauters, Wouter, MD, PhD and Hellings, Peter, MD, PhD and Brusselle, Guy, MD, PhD and De Bacquer, Dirk, MD, PhD and van Cauwenberge, Paul, MD, PhD and Bachert, Claus, MD, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2012, Volume 131, Issue 1, pp. 110 - 116.e1
Allergy and Immunology | Omalizumab | anti-IgE | asthma | local IgE | quality of life | nasal polyposis | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Otorhinolaryngology. Stomatology | Biological and medical sciences | Medical sciences | Upper respiratory tract, upper alimentary tract, paranasal sinuses, salivary glands: diseases, semeiology | Tumors | Antibodies, Anti-Idiotypic - adverse effects | Antibodies, Monoclonal, Humanized - adverse effects | Nasal Polyps - immunology | Antibodies, Monoclonal, Humanized - therapeutic use | Humans | Middle Aged | Male | Treatment Outcome | Nasal Polyps - drug therapy | Asthma - drug therapy | Anti-Allergic Agents - therapeutic use | Nasal Polyps - complications | Asthma - complications | Anti-Allergic Agents - adverse effects | Asthma - immunology | Adult | Female | Antibodies, Anti-Idiotypic - therapeutic use | Comorbidity | Immunoglobulin E | Respiratory agents | Universities and colleges | Nasal polyps | Health aspects | Asthma | Hospitals | Mental health | Ear diseases | Otolaryngology | Drug therapy | Allergies | Inventories | Scanning | Cytokines | Hypersensitivity | biomarkers | Helper cells | Clinical trials | Wheezing | Inflammation | Lymphocytes T | Eosinophilia | Quality of life | Respiratory tract | Dyspnea | Computed tomography | Sinus | Nose | Olfaction | Monoclonal antibodies | Respiration | rhinosinusitis | Polyps | Index Medicus | Abridged Index Medicus | Medicin och hälsovetenskap
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9. Full Text Presence of IL-5 protein and IgE antibodies to staphylococcal enterotoxins in nasal polyps is associated with comorbid asthma
by Bachert, Claus, MD, PhD and Zhang, Nan, MD, PhD and Holtappels, Gabriele and De Lobel, Lizzy and van Cauwenberge, Paul, MD, PhD and Liu, Shixi, MD, PhD and Lin, Ping, PhD and Bousquet, Jean, MD, PhD and Van Steen, Kristel, PhD
Journal of allergy and clinical immunology, ISSN 0091-6749, 2010, Volume 126, Issue 5, pp. 962 - 968.e6
Allergy and Immunology | nasal polyps | Staphylococcus aureus enterotoxins | asthma | Chronic rhinosinusitis | IgE | T-cell cytokines | Nasal polyps | Asthma | Allergy | Immunology | Life Sciences & Biomedicine | Science & Technology | Fundamental and applied biological sciences. Psychology | Fundamental immunology | Immunopathology | Infectious diseases | Bacterial diseases | Human bacterial diseases | Sarcoidosis. Granulomatous diseases of unproved etiology. Connective tissue diseases. Elastic tissue diseases. Vasculitis | Staphylococcal infections, streptococcal infections, pneumococcal infections | Biological and medical sciences | Medical sciences | Inflammation - pathology | Nasal Polyps - immunology | Nasal Polyps - pathology | Comorbidity | Humans | Middle Aged | Male | Inflammation - immunology | Interleukin-5 - immunology | Young Adult | Immunoglobulin E - immunology | Enterotoxins - immunology | Adolescent | Asthma - immunology | Adult | Female | Staphylococcus aureus - immunology | Aged | Nasal Polyps - epidemiology | Asthma - pathology | Child | Asthma - epidemiology | Computer science | Staphylococcus aureus infections | Immunoglobulin E | Universities and colleges | Cytokines | Allergies | Age | Index Medicus | Abridged Index Medicus