Articles

Search Articles

Advanced search
Help

Catalogue

Articles

Databases

X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (2774) 2774
Book Review (398) 398
Publication (164) 164
Book Chapter (14) 14
Newsletter (11) 11
Book / eBook (10) 10
Conference Proceeding (3) 3
Magazine Article (1) 1
Newspaper Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
index medicus (2582) 2582
humans (2546) 2546
male (1466) 1466
female (1451) 1451
adult (1334) 1334
middle aged (1144) 1144
otorhinolaryngology (857) 857
nasal polyps - metabolism (843) 843
nasal polyps (751) 751
immunology (658) 658
chronic disease (655) 655
asthma (629) 629
chronic rhinosinusitis (608) 608
allergy (604) 604
aged (599) 599
nasal mucosa - metabolism (584) 584
nasal polyps - pathology (522) 522
inflammation (519) 519
expression (486) 486
adolescent (468) 468
immunohistochemistry (420) 420
cells, cultured (383) 383
sinusitis - metabolism (366) 366
young adult (365) 365
abridged index medicus (334) 334
nasal polyps - immunology (324) 324
rhinitis - metabolism (318) 318
nasal mucosa - pathology (302) 302
animals (297) 297
case-control studies (274) 274
sinusitis - immunology (274) 274
allergic rhinitis (263) 263
nasal polyps - complications (253) 253
cells (252) 252
cytokines (243) 243
surgery (240) 240
nasal polyposis (235) 235
nose (235) 235
sinusitis (232) 232
gene expression (231) 231
rhinitis - immunology (229) 229
mucosa (223) 223
rhinosinusitis (222) 222
respiratory system (221) 221
sinusitis - complications (209) 209
disease (208) 208
analysis (205) 205
rhinitis (202) 202
sinusitis - pathology (199) 199
eosinophils (194) 194
nasal mucosa - immunology (194) 194
proteins (188) 188
medicine, research & experimental (178) 178
rhinitis - complications (178) 178
polyps (177) 177
pathogenesis (176) 176
child (172) 172
epithelial cells - metabolism (170) 170
allergies (169) 169
aspirin - adverse effects (169) 169
enzyme-linked immunosorbent assay (168) 168
eosinophils - metabolism (167) 167
rhinitis - pathology (167) 167
medicine & public health (166) 166
cytokines - metabolism (163) 163
nasal polyps - drug therapy (159) 159
rna, messenger - metabolism (158) 158
nasal polyp (157) 157
nasal polyps - genetics (156) 156
cell biology (152) 152
chronic sinusitis (147) 147
epithelial-cells (147) 147
otolaryngology (142) 142
reverse transcriptase polymerase chain reaction (141) 141
nasal mucosa - drug effects (139) 139
aspirin (137) 137
allergy and immunology (131) 131
nasal mucosa - cytology (131) 131
activation (129) 129
endoscopy (128) 128
sinuses (121) 121
epithelium (120) 120
endoscopic sinus surgery (119) 119
pharmacology & pharmacy (119) 119
research (119) 119
diagnosis (118) 118
eosinophils - immunology (118) 118
nasal polyps - surgery (118) 118
mice (117) 117
prospective studies (117) 117
nasal polyps - etiology (116) 116
messenger-rna (115) 115
cystic fibrosis (114) 114
corticosteroids (113) 113
epithelial cells (113) 113
rna, messenger - genetics (113) 113
administration, intranasal (112) 112
sinusitis - genetics (111) 111
treatment outcome (110) 110
gene expression regulation (108) 108
more...
Library Location Library Location
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (2535) 2535
Chinese (171) 171
German (25) 25
Russian (20) 20
Polish (17) 17
Japanese (13) 13
French (10) 10
Italian (6) 6
Spanish (5) 5
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


1. Full Text IL-33-responsive innate lymphoid cells are an important source of IL-13 in chronic rhinosinusitis with nasal polyps
by Shaw, Joanne L and Fakhri, Samer and Citardi, Martin J and Porter, Paul C and Corry, David B and Kheradmand, Farrah and Liu, Yong-Jun and Luong, Amber
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 08/2013, Volume 188, Issue 4, pp. 432 - 439
Rationale: Chronic rhinosinusitis (CRS) withoutnasalpolyps (CRSsNP) and CRS with nasal polyps (CRSwNP) are associated with Th1 and Th2 cytokine polarization,... 
Innate lymphoid cells | Alternaria alternata | Aspergillus fumigatus | Epithelial cells | IL-33 | IMMUNITY | CYTOKINES | INDUCED AIRWAY INFLAMMATION | MAST-CELLS | epithelial cells | RECEPTOR | innate lymphoid cells | FAMILY | ST2 | PATHOGENESIS | RESPIRATORY SYSTEM | EXPRESSION | CRITICAL CARE MEDICINE | Epithelial Cells - metabolism | Humans | Middle Aged | Rhinitis - physiopathology | Male | Th2 Cells - immunology | Interleukins - metabolism | Sinusitis - complications | Flow Cytometry | Interleukins - physiology | Immunity, Innate - physiology | Sinusitis - immunology | Aged, 80 and over | Sinusitis - physiopathology | Adult | Female | Nasal Polyps - metabolism | Rhinitis - immunology | Sinusitis - metabolism | Interleukin-33 | Th2 Cells - metabolism | Mucous Membrane - metabolism | Rhinitis - metabolism | Rhinitis - complications | Aged | Chronic Disease | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
2. Full Text Thymic stromal lymphopoietin activity is increased in nasal polyps of patients with chronic rhinosinusitis
by Nagarkar, Deepti R., PhD and Poposki, Julie A., MS and Tan, Bruce K., MD and Comeau, Michael R., BS and Peters, Anju T., MD and Hulse, Kathryn E., PhD and Suh, Lydia A., BS and Norton, James, MS and Harris, Kathleen E., BS and Grammer, Leslie C., MD and Chandra, Rakesh K., MD and Conley, David B., MD and Kern, Robert C., MD and Schleimer, Robert P., PhD and Kato, Atsushi, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2013, Volume 132, Issue 3, pp. 593 - 600.e12
Background Chronic rhinosinusitis with nasal polyps (CRSwNP) is associated with TH 2-dominant inflammation. Thymic stromal lymphopoietin (TSLP) is a cytokine... 
Allergy and Immunology | TH2 cells | thymic stromal lymphopoietin | Chronic rhinosinusitis | proteases | nasal polyps | epithelial cells | IL-5 | mast cells | AIRWAY EPITHELIAL-CELLS | ALLERGIC INFLAMMATION | SEVERE ASTHMA | INCREASED EXPRESSION | TSLP | T(H)2 cells | INNATE LYMPHOID-CELLS | IMMUNOLOGY | CUTTING EDGE | TNF FAMILY | ALLERGY | HUMAN MAST-CELLS | ACTIVATING FACTOR | Sinusitis - metabolism | Epithelial Cells - metabolism | Cytokines - metabolism | Humans | Middle Aged | Cells, Cultured | Male | RNA, Messenger - metabolism | Young Adult | Rhinitis - metabolism | Adolescent | Mast Cells - metabolism | Nasal Mucosa - cytology | Adult | Female | Aged | Nasal Mucosa - metabolism | Protein Processing, Post-Translational | Nasal Polyps - metabolism | Cytokines - genetics | Peptide Hydrolases - metabolism | Inflammation | Nurse practitioners | RNA | Dendritic cells | Nasal polyps | Proteins | Studies | Cytokines | Otolaryngology | Methods | Quality of life | Asthma | Chronic illnesses | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
3. Full Text Nasal IL-4+ CXCR5+ CD4+ T follicular helper cell counts correlate with local IgE production in eosinophilic nasal polyps
by Zhang, Ya-Na, MD, PhD and Song, Jia, MD and Wang, Hai, MD and Wang, Heng, MD, PhD and Zeng, Ming, MD, PhD and Zhai, Guan-Ting, MD and Ma, Jin, MD and Li, Zhi-Yong, MD and Liao, Bo, MD and Wang, Bao-Feng, MD and Zhen, Zhen, MD, PhD and Wang, Nan, MD, PhD and Cao, Ping-Ping, MD, PhD and Lin, Peng, MD and Ning, Qin, MD, PhD and Liu, Zheng, MD, PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2015, Volume 137, Issue 2, pp. 462 - 473
Background Locally produced IgE contributes to the initiation and development of eosinophilic inflammation in eosinophilic nasal polyps independent of systemic... 
Allergy and Immunology | B cell | IgE | IL-4 | eosinophil | ectopic lymphoid structure | nasal polyp | T follicular helper cell | DENDRITIC CELLS | IMMUNOLOGY | CHRONIC RHINOSINUSITIS | ALLERGY | INFLAMMATION | DISEASE | MEMORY TFH CELLS | ANTIBODY-RESPONSES | BLOOD | T-Lymphocyte Subsets - immunology | Eosinophilia - metabolism | Humans | Immunoglobulin E - biosynthesis | Nasal Mucosa - pathology | Nasal Polyps - diagnosis | Eosinophilia - pathology | Immunoglobulin E - immunology | T-Lymphocytes, Helper-Inducer - immunology | Nasal Mucosa - metabolism | Nasal Polyps - metabolism | B-Lymphocytes - metabolism | Nasal Polyps - immunology | Antibody Formation - immunology | Nasal Polyps - pathology | Receptors, CXCR5 - metabolism | T-Lymphocytes, Helper-Inducer - metabolism | Interleukin-4 - metabolism | Immunophenotyping | Phenotype | B-Lymphocytes - immunology | Eosinophilia - immunology | Nasal Mucosa - immunology | T-Lymphocyte Subsets - metabolism | Biomarkers | Lymphocyte Count | Proteins | Immunoglobulins | Cytokines | Lymphocytes | Rodents | T cell receptors | Inflammation | Patients | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
4. Full Text Interaction of thymic stromal lymphopoietin, IL‐33, and their receptors in epithelial cells in eosinophilic chronic rhinosinusitis with nasal polyps
by Liao, B and Cao, P.‐P and Zeng, M and Zhen, Z and Wang, H and Zhang, Y.‐N and Hu, C.‐Y and Ma, J and Li, Z.‐Y and Song, J and Liu, J.‐X and Peng, L.‐Y and Liu, Y and Ning, Q and Liu, Z
Allergy, ISSN 0105-4538, 09/2015, Volume 70, Issue 9, pp. 1169 - 1180
BackgroundThymic stromal lymphopoietin (TSLP), IL-25, and IL-33 system contribute to the initiation and development of Th2 responses. This study aimed to... 
type 2 T‐helper cell response | interleukin 33 | cross‐regulation | thymic stromal lymphopoietin | receptor | cross-regulation | type 2 T-helper cell response | INCREASED EXPRESSION | MEDIATOR | IGE | CYTOKINE | INNATE LYMPHOID-CELLS | IMMUNOLOGY | ST2 | ALLERGY | Interleukin-1 Receptor-Like 1 Protein | Epithelial Cells - metabolism | Humans | Middle Aged | Male | Rhinitis - diagnosis | Th2 Cells - immunology | Nasal Polyps - diagnosis | Case-Control Studies | Young Adult | Sinusitis - immunology | Adult | Female | Receptors, Cytokine - metabolism | Nasal Polyps - metabolism | Severity of Illness Index | Nasal Polyps - immunology | Rhinitis - immunology | Receptors, Interleukin-7 - metabolism | Sinusitis - metabolism | Cytokines - metabolism | Signal Transduction | Immunomodulation | Sinusitis - diagnosis | Receptors, Cell Surface - metabolism | Th2 Cells - metabolism | Toll-Like Receptors - agonists | Interleukin-17 - metabolism | Rhinitis - metabolism | Interleukin-33 - metabolism | Protein Binding | Interleukins | Nasal polyps | Analysis | Cytokines | Rodents | Allergies | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
5. Full Text Unsupervised phenotyping of Severe Asthma Research Program participants using expanded lung data
by Wu, Wei, PhD and Bleecker, Eugene, MD and Moore, Wendy, MD and Busse, William W., MD and Castro, Mario, MD and Chung, Kian Fan, MD and Calhoun, William J., MD and Erzurum, Serpil, MD and Gaston, Benjamin, MD and Israel, Elliot, MD and Curran-Everett, Douglas, PhD and Wenzel, Sally E., MD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2014, Volume 133, Issue 5, pp. 1280 - 1288
Background Previous studies have identified asthma phenotypes based on small numbers of clinical, physiologic, or inflammatory characteristics. However, no... 
Allergy and Immunology | variable analysis | Asthma phenotyping | unsupervised approaches | supervised machine learning approaches | WHEEZE | ALLERGY | IMMUNOLOGY | CLUSTER-ANALYSIS | YOUNG-CHILDREN | Eosinophilia - metabolism | Asthma - metabolism | Humans | Middle Aged | Bronchoalveolar Lavage | Male | Eosinophilia - pathology | Adult | Female | Lung - metabolism | Eosinophilia - drug therapy | Nasal Polyps - metabolism | Eosinophilia - physiopathology | Severity of Illness Index | Lung - pathology | Nasal Polyps - pathology | Asthma - physiopathology | Lung - parasitology | Nasal Polyps - drug therapy | Asthma - drug therapy | Phenotype | Nasal Polyps - complications | Asthma - complications | Nasal Polyps - physiopathology | Age of Onset | Eosinophilia - complications | Asthma - pathology | Adrenal Cortex Hormones - administration & dosage | Computer science | Machine learning | Asthma | Cluster analysis | Studies | Variables | Algorithms | Leukemia | Classification | Patients | Methods | Information theory | Index Medicus | Abridged Index Medicus | asthma phenotyping
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
6. Expression and functional analysis of CST1 in intractable nasal polyps
by Kato, Yukinori and Takabayashi, Tetsuji and Sakashita, Masafumi and Imoto, Yoshimasa and Tokunaga, Takahiro and Ninomiya, Takahiro and Morikawa, Taiyo and Yoshida, Kanako and Noguchi, Emiko and Fujieda, Shigeharu
American Journal of Respiratory Cell and Molecular Biology, ISSN 1044-1549, 10/2018, Volume 59, Issue 4, pp. 448 - 457
In this study, we found Cystatin SN (CST1), a type 2 cystatin subfamily member, to be highly expressed in nasal polyps from patients with intractable chronic... 
CST1 | TSLP | Nasal polyps | Eosinophilic chronic rhinosinusitis | Protease inhibitor | AIRWAY EPITHELIAL-CELLS | ALLERGIC INFLAMMATION | protease inhibitor | BIOCHEMISTRY & MOLECULAR BIOLOGY | INNATE LYMPHOID-CELLS | eosinophilic chronic rhinosinusitis | IL-33 | PERIOSTIN | THYMIC STROMAL LYMPHOPOIETIN | CELL BIOLOGY | PATHOGENESIS | CYSTATIN-SN | RESPIRATORY SYSTEM | nasal polyps | ASTHMA | Inflammation - pathology | Epithelial Cells - metabolism | Humans | Middle Aged | Salivary Cystatins - metabolism | Male | RNA, Messenger - metabolism | Young Adult | Sinusitis - genetics | Nasal Polyps - genetics | Aged, 80 and over | Sinusitis - pathology | Adult | Female | Eosinophils - pathology | Receptors, Cytokine - metabolism | Nasal Polyps - metabolism | Child | Fibroblasts - metabolism | Salivary Cystatins - genetics | Severity of Illness Index | Nasal Polyps - pathology | Cytokines - metabolism | RNA, Messenger - genetics | Fibroblasts - pathology | Disease Progression | Models, Biological | Adolescent | Aged | Interleukin-1 Receptor-Like 1 Protein - metabolism | Chronic Disease | Immunohistochemistry | Cystatin | Disease | Transcription | Laboratories | Epithelial cells | Pathogenesis | Rhinosinusitis | Otolaryngology | Interleukin 4 | Sinuses | Next-generation sequencing | Surgery | Nose | Fibroblasts | Endoscopy | Chronic illnesses | Cytokines | Leukocytes (eosinophilic) | Double-stranded RNA | Inflammation | Gene expression | Allergies | Asthma | Studies | Thymic stromal lymphopoietin | Ligands | Polyps
Journal Article
Details down arrow
7. Full Text Phenotypic and functional characteristics of IL-21-expressing CD8+ T cells in human nasal polyps
by Xiao, Li and Jia, Lei and Bai, Lu and He, Long and Yang, Binyan and Wu, Changyou and Li, Huabin
Scientific Reports, ISSN 2045-2322, 07/2016, Volume 6, Issue 1, pp. 30362 - 30362
Although CD4(+) T cells are recognized to play an important role in the inflammatory response of nasal polyps (NPs), the biological functions of CD8(+) T cells... 
IMMUNITY | DENDRITIC CELLS | IFN-GAMMA | MULTIDISCIPLINARY SCIENCES | MUCOSAL INFLAMMATION | PERIPHERAL-BLOOD | INTERLEUKIN-21 | DIFFERENTIATION | EXPRESSION | T-CELLS | CHRONIC RHINOSINUSITIS | Recombinant Proteins - metabolism | Receptors, CXCR5 - metabolism | Cell Separation | Humans | Middle Aged | Male | Interferon-gamma - metabolism | Case-Control Studies | Interleukins - metabolism | Young Adult | Interleukin-17 - metabolism | Phenotype | CD40 Ligand - metabolism | Flow Cytometry | Adolescent | CD8-Positive T-Lymphocytes - metabolism | Adult | Female | Aged | Nasal Polyps - metabolism | B-Lymphocytes - metabolism | Immunoglobulin G - metabolism | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
8. Full Text Osteitis is associated with dysregulated pro‐osteoblastic activity in patients with nasal polyps
by Wu, Dawei and Nocera, Angela L and Mueller, Sarina K and Finn, Kristen and Libermann, Towia A and Bleier, Benjamin S
The Laryngoscope, ISSN 0023-852X, 03/2019, Volume 129, Issue 3, pp. E102 - E109
Objectives/Hypothesis The overlying inflammatory mucosa plays a crucial role in the initiation of osteitis; however, the molecular mechanism is unclear. The... 
chronic rhinosinusitis | nasal polyps | bone morphogenetic protein pathway | Osteitis | SINUSITIS | MEDICINE, RESEARCH & EXPERIMENTAL | BONE MORPHOGENETIC PROTEINS | HISTOPATHOLOGY | ETHMOID BONE | OTORHINOLARYNGOLOGY | GENES | MICE | CT ANALYSIS | EXPRESSION | Osteitis - metabolism | Sinusitis - metabolism | Prospective Studies | Signal Transduction | Down-Regulation | Humans | Middle Aged | Male | Case-Control Studies | Bone Morphogenetic Proteins - metabolism | Rhinitis - metabolism | Adult | Female | Nasal Polyps - metabolism | Osteoblasts - metabolism | Bone morphogenetic proteins | Care and treatment | Phosphatases | RNA | Nasal polyps | Analysis | Proteins | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
9. Full Text Expression of IL‐33 and its receptor ST2 in chronic rhinosinusitis with nasal polyps
by Baba, Shintaro and Kondo, Kenji and Kanaya, Kaori and Suzukawa, Keigo and Ushio, Munetaka and Urata, Shinji and Asakage, Takahiro and Kakigi, Akinobu and Suzukawa, Maho and Ohta, Ken and Yamasoba, Tatsuya
The Laryngoscope, ISSN 0023-852X, 04/2014, Volume 124, Issue 4, pp. E115 - E122
Objectives/Hypothesis Interleukin (IL)-33 is a novel member of the IL-1 cytokine family and a ligand for the orphan IL-1 family receptor ST2. IL-33 induces T... 
ST2 | IL‐33 | expression | Cytokine | inflammatory cells | eosinophil | rhinosinusitis | nasal polyp | IL-33 | TARGET | MEDICINE, RESEARCH & EXPERIMENTAL | CELLS | PROTEIN | INTERLEUKIN-33 | IL-13 | OTORHINOLARYNGOLOGY | POSITION PAPER | Immunohistochemistry | Interleukin-1 Receptor-Like 1 Protein | Eosinophils - metabolism | Humans | Middle Aged | Male | Nasal Mucosa - pathology | Sinusitis - complications | Interleukins - genetics | Sinusitis - genetics | Nasal Polyps - genetics | Adult | Female | Nasal Mucosa - metabolism | Receptors, Cell Surface - biosynthesis | Interleukins - biosynthesis | Nasal Polyps - metabolism | Real-Time Polymerase Chain Reaction | Sinusitis - metabolism | Enzyme-Linked Immunosorbent Assay | Interleukin-33 | RNA, Messenger - genetics | Gene Expression Regulation | Rhinitis - genetics | Nasal Polyps - complications | Rhinitis - metabolism | Rhinitis - complications | Aged | Chronic Disease | Receptors, Cell Surface - genetics | Enzymes | RNA | Nasal polyps | Atopic dermatitis | Enzyme-linked immunosorbent assay | Medical research | Rodents | Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
10. Full Text Nasal IL-5 levels determine the response to anti–IL-5 treatment in patients with nasal polyps
by Gevaert, Philippe and Lang-Loidolt, Doris and Lackner, Andreas and Stammberger, Heinz and Staudinger, Heribert and Van Zele, Thibaut and Holtappels, Gabriele and Tavernier, Jan and van Cauwenberge, Paul and Bachert, Claus
The Journal of Allergy and Clinical Immunology, ISSN 0091-6749, 2006, Volume 118, Issue 5, pp. 1133 - 1141
Chronic rhinosinusitis with nasal polyps is characterized by an eosinophilic inflammation and high IL-5 levels. Antagonizing the effect of IL-5 is a potential... 
IL-5 receptor α | nasal polyps | anti–IL-5 | eosinophils | IL-5 | Chronic rhinosinusitis | anti-IL-5 | eosinphils | HYPERREACTIVITY | CYTOKINES | MEMBRANE | HUMAN INTERLEUKIN-5 RECEPTOR | IMMUNOLOGY | HUMAN EOSINOPHILS | ALLERGY | ANTI-INTERLEUKIN-5 ANTIBODY | ALPHA EXPRESSION | chronic rhinosinusitis | ASTHMA | IL-5 receptor alpha | INDUCED AIRWAY HYPERRESPONSIVENESS | DECREASED EXPRESSION | Nasal Polyps - immunology | Injections, Intravenous | Double-Blind Method | Interleukin-5 - metabolism | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Antibodies, Monoclonal - pharmacokinetics | Antibodies, Monoclonal - therapeutic use | Male | Interleukin-5 - biosynthesis | Nasal Polyps - therapy | Interleukin-5 - immunology | Antibodies, Monoclonal, Humanized | Interleukin-5 - antagonists & inhibitors | Nasal Mucosa - immunology | Adolescent | Adult | Female | Nasal Mucosa - metabolism | Nasal Polyps - metabolism | Nasal polyps | Medical colleges | Care and treatment | Clinical trials | Otolaryngology | Drug therapy | Surgery | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
11. Full Text Glandular mast cells with distinct phenotype are highly elevated in chronic rhinosinusitis with nasal polyps
by Takabayashi, Tetsuji, MD and Kato, Atsushi, PhD and Peters, Anju T., MD and Suh, Lydia A., BSc and Carter, Roderick, BSc and Norton, James, MS and Grammer, Leslie C., MD and Tan, Bruce K., MD and Chandra, Rakesh K., MD and Conley, David B., MD and Kern, Robert C., MD and Fujieda, Shigeharu, MD and Schleimer, Robert P., PhD
Journal of Allergy and Clinical Immunology, The, ISSN 0091-6749, 2012, Volume 130, Issue 2, pp. 410 - 420.e5
Background Although chronic rhinosinusitis (CRS) with nasal polyps (CRSwNP) is characterized by TH 2 inflammation, the role of mast cells is poorly understood.... 
Allergy and Immunology | nasal polyps | Chronic rhinosinusitis | carboxypeptidase A3 (CPA3) | mast cells | tryptase | chymase | IMMUNITY | ACTIVATION | EOSINOPHILS | RELEASE | IMMUNOLOGY | EPITHELIAL-CELLS | ALLERGY | DISEASE | GENE-EXPRESSION | ASTHMA | ACCUMULATION | INFLAMMATORY MEDIATORS | Immunohistochemistry | Tryptases - metabolism | RNA, Messenger - immunology | Chymases - metabolism | Humans | Middle Aged | Male | Sinusitis - complications | Epithelium - immunology | RNA, Messenger - biosynthesis | Sinusitis - immunology | Mast Cells - metabolism | Sinusitis - pathology | Adult | Female | Nasal Polyps - metabolism | Real-Time Polymerase Chain Reaction | Tryptases - genetics | Mast Cells - immunology | Nasal Polyps - immunology | Rhinitis - immunology | Epithelium - pathology | Gene Expression | Nasal Polyps - pathology | Sinusitis - metabolism | Enzyme-Linked Immunosorbent Assay | Epithelium - metabolism | Nasal Lavage Fluid - cytology | Nasal Lavage Fluid - chemistry | Carboxypeptidases A - metabolism | Chymases - genetics | Nasal Polyps - complications | Rhinitis - metabolism | Mast Cells - pathology | Adolescent | Rhinitis - complications | Carboxypeptidases A - genetics | Rhinitis - pathology | Chronic Disease | Medical colleges | Polyps (Pathology) | Nurse practitioners | Nurses | Stem cells | Genetic aspects | Nasal polyps | Proteins | Studies | Sinuses | Disease | Pathogenesis | Allergies | Age | Methods | Chronic illnesses | Index Medicus | Abridged Index Medicus | Glands | Proteinase | Helper cells | Carboxypeptidase | Inflammation | Lymphocytes T | mRNA | Epithelium | Chymase | Polymerase chain reaction | Tryptase | lamina propria | Mast cells | Immunofluorescence | rhinosinusitis | Polyps | Enzyme-linked immunosorbent assay
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights
12. Full Text Excessive fibrin deposition in nasal polyps caused by fibrinolytic impairment through reduction of tissue plasminogen activator expression
by Takabayashi, Tetsuji and Kato, Atsushi and Peters, Anju T and Hulse, Kathryn E and Suh, Lydia A and Carter, Roderick and Norton, James and Grammer, Leslie C and Cho, Seong H and Tan, Bruce K and Chandra, Rakesh K and Conley, David B and Kern, Robert C and Fujieda, Shigeharu and Schleimer, Robert P
American Journal of Respiratory and Critical Care Medicine, ISSN 1073-449X, 01/2013, Volume 187, Issue 1, pp. 49 - 57
Rationale: Nasal polyps (NPs) are characterized by intense edema or formation of pseudocysts filled with plasma proteins, mainly albumin. However, the... 
Fibrin | Chronic rhinosinusitis | Nasal polyps | Tissue plasminogen activator | Fibrinolysis | SYSTEM | RECEPTOR-RELATED PROTEIN | tissue plasminogen activator | THROMBIN | TNF FAMILY | fibrinolysis | SIGNAL-TRANSDUCTION | PATHOGENESIS | MULTIPLE-SCLEROSIS | RESPIRATORY SYSTEM | INFLAMMATION | chronic rhinosinusitis | nasal polyps | COAGULATION | fibrin | CRITICAL CARE MEDICINE | Epithelium - metabolism | Tissue Plasminogen Activator - metabolism | Humans | Middle Aged | Male | Blood Proteins - metabolism | Th2 Cells - metabolism | Down-Regulation - physiology | Young Adult | Edema - metabolism | Adolescent | Fluorescent Antibody Technique | Adult | Female | Aged | Nasal Mucosa - metabolism | Fibrinolysis - physiology | Fibrin - metabolism | Nasal Polyps - metabolism | Index Medicus | Abridged Index Medicus
Journal Article
Details down arrow
Digital rights down arrow
loading Loading Rights