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Oncogene, ISSN 0950-9232, 04/2015, Volume 34, Issue 17, pp. 2156 - 2166
The epithelial-mesenchymal transition (EMT) is crucial to cancer progression and metastasis. Although multiple cellular miRNAs have been identified to regulate... 
PROTEIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | E-CADHERIN | CANCER STEM-CELLS | ENCODED MICRORNAS | CELL BIOLOGY | EPITHELIAL-MESENCHYMAL TRANSITION | LUNG-CANCER | INVASION | ONCOLOGY | TARGETING PTEN | GENETICS & HEREDITY | EXPRESSION | EPSTEIN-BARR-VIRUS | Nasopharyngeal Neoplasms - genetics | Nasopharyngeal Neoplasms - metabolism | Carcinoma | Herpesvirus 4, Human - genetics | Humans | Nasopharyngeal Neoplasms - virology | Glycogen Synthase Kinase 3 beta | Phosphatidylinositol 3-Kinases - metabolism | RNA, Neoplasm - metabolism | Proto-Oncogene Proteins c-akt - genetics | Nasopharyngeal Neoplasms - pathology | Neoplasm Metastasis | Cell Nucleus - metabolism | RNA, Viral - genetics | Cell Nucleus - pathology | Epithelial-Mesenchymal Transition | Epstein-Barr Virus Infections - genetics | Female | RNA, Viral - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Cell Line | PTEN Phosphohydrolase - genetics | Nasopharyngeal Carcinoma | Neoplasm Invasiveness | PTEN Phosphohydrolase - biosynthesis | Signal Transduction - genetics | Glycogen Synthase Kinase 3 - metabolism | Epstein-Barr Virus Infections - pathology | Phosphatidylinositol 3-Kinases - genetics | Cell Nucleus - genetics | Glycogen Synthase Kinase 3 - genetics | RNA, Neoplasm - genetics | Herpesvirus 4, Human - metabolism | Epstein-Barr Virus Infections - metabolism | MicroRNA | Biological products | Innovations | Development and progression | Epstein-Barr virus | Genetic aspects | Nasopharyngeal cancer | Gene expression | Health aspects | Cellular biology | Metastasis | Cancer | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 04/2013, Volume 73, Issue 7, pp. 2322 - 2332
Tumor-initiating cells (TIC), also known as cancer stem cells, are regarded widely as a specific subpopulation of cells needed for cancer initiation and... 
SURVIVAL | NASOPHARYNGEAL CARCINOMA | STEM-CELLS | SUPPRESSOR GENE | ANGIOGENESIS | ONCOLOGY | GROWTH | SELF-RENEWAL | ETS-1 | IDENTIFICATION | EXPRESSION | Liver Neoplasms, Experimental - secondary | RNA, Small Interfering - genetics | Cell Proliferation | Carcinoma, Squamous Cell - genetics | Carcinoma, Squamous Cell - metabolism | Humans | Lung Neoplasms - metabolism | Middle Aged | Male | Gene Expression Profiling | Immunoenzyme Techniques | Esophageal Neoplasms - pathology | Liver Neoplasms, Experimental - metabolism | Flow Cytometry | Lung Neoplasms - secondary | Neoplastic Stem Cells - metabolism | Esophageal Neoplasms - metabolism | Thy-1 Antigens - genetics | Epithelial-Mesenchymal Transition | Biomarkers, Tumor - metabolism | Neoplastic Stem Cells - pathology | Female | Cell Differentiation | Liver Neoplasms, Experimental - genetics | Real-Time Polymerase Chain Reaction | Thy-1 Antigens - chemistry | Lung Neoplasms - genetics | Signal Transduction | RNA, Messenger - genetics | Lymphatic Metastasis | Mice, SCID | Reverse Transcriptase Polymerase Chain Reaction | Cell Adhesion | Blotting, Western | Disease Progression | Thy-1 Antigens - metabolism | Animals | Esophageal Neoplasms - genetics | Carcinoma, Squamous Cell - secondary | Mice, Inbred NOD | Biomarkers, Tumor - genetics | Mice | Neoplasm Staging | Apoptosis | Cell Movement | Index Medicus
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 12/2009, Volume 119, Issue 12, pp. 3626 - 3636
The polycomb group protein B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) is dysregulated in various cancers, and its upregulation strongly correlates... 
MEDICINE, RESEARCH & EXPERIMENTAL | BREAST-CANCER CELLS | DEVELOPMENTAL REGULATORS | CELLULAR MEMORY | E-CADHERIN EXPRESSION | HEMATOPOIETIC STEM-CELLS | PROSTATE-CANCER | MYC TRANSGENIC MICE | SELF-RENEWAL | NF-KAPPA-B | TRANSCRIPTION FACTOR | Nasopharyngeal Neoplasms - genetics | Neoplasm Transplantation | Nasopharyngeal Neoplasms - metabolism | Epithelial Cells - metabolism | Cadherins - metabolism | Humans | Glycogen Synthase Kinase 3 beta | Transplantation, Heterologous | Phosphatidylinositol 3-Kinases - metabolism | Mesoderm - cytology | Repressor Proteins - antagonists & inhibitors | Nasopharyngeal Neoplasms - pathology | Cadherins - genetics | Epithelial Cells - cytology | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Nasopharyngeal Neoplasms - etiology | Snail Family Transcription Factors | Nasopharynx - metabolism | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | PTEN Phosphohydrolase - genetics | Proto-Oncogene Proteins - antagonists & inhibitors | Signal Transduction | Neoplasm Invasiveness | Down-Regulation | Gene Silencing | PTEN Phosphohydrolase - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Glycogen Synthase Kinase 3 - metabolism | Transcription Factors - metabolism | Animals | Polycomb Repressive Complex 1 | Mice, Nude | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mesoderm - metabolism | Mice | Nasopharynx - cytology | Chromatin | Care and treatment | Lymphomas | Research | Analysis | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 04/2016, Volume 7, Issue 1, pp. 11309 - 11309
The biological role of miR-3188 has not yet been reported in the context of cancer. In this study, we observe that miR-3188 not only reduces cell-cycle... 
EPITHELIAL-MESENCHYMAL TRANSITION | CANCER-CELLS | BREAST-CANCER | FORKHEAD TRANSCRIPTION FACTOR | SIGNALING PATHWAY | MULTIDISCIPLINARY SCIENCES | SQUAMOUS-CELL CARCINOMA | C-MYC | TUMOR-SUPPRESSOR | CISPLATIN RESISTANCE | PROMOTES | Nasopharyngeal Neoplasms - genetics | Neoplasm Transplantation | Nasopharyngeal Neoplasms - metabolism | Carcinoma | Prognosis | TOR Serine-Threonine Kinases - metabolism | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | JNK Mitogen-Activated Protein Kinases - metabolism | Male | MicroRNAs - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Proto-Oncogene Proteins c-akt - genetics | Nasopharyngeal Neoplasms - pathology | TOR Serine-Threonine Kinases - genetics | Cell Transformation, Neoplastic - genetics | Forkhead Transcription Factors - metabolism | Aged, 80 and over | Adult | Female | JNK Mitogen-Activated Protein Kinases - genetics | Proto-Oncogene Proteins c-akt - metabolism | Nasopharyngeal Neoplasms - diagnosis | Nasopharyngeal Carcinoma | Signal Transduction | Forkhead Transcription Factors - genetics | Cell Transformation, Neoplastic - metabolism | Phosphatidylinositol 3-Kinases - genetics | Drug Resistance, Neoplasm - genetics | Feedback, Physiological | Animals | Survival Analysis | Cell Line, Tumor | Aged | Forkhead Box Protein O1 | Mice | MicroRNAs - genetics | Cell Transformation, Neoplastic - pathology | Neoplasm Staging | Index Medicus
Journal Article
Medicine (United States), ISSN 0025-7974, 2016, Volume 95, Issue 35, pp. e4592 - e4592
Journal Article
Cancer Research, ISSN 0008-5472, 04/2011, Volume 71, Issue 7, pp. 2686 - 2696
Journal Article
Nature Genetics, ISSN 1061-4036, 07/2010, Volume 42, Issue 7, pp. 599 - 603
Journal Article
International Journal of Cancer, ISSN 0020-7136, 03/2015, Volume 136, Issue 5, pp. E301 - E312
More than 75% of nasopharyngeal carcinoma (NPC) patients have already developed local or regional spread at diagnosis, which hampers effective treatment and... 
NPC | microRNA | biomarker | EBV BART | Epstein‐Barr virus | Biomarker | Epstein-Barr virus | CURRENT MANAGEMENT | FUTURE-DIRECTIONS | CHINA | 7TH EDITION | CELL-LINES | QUANTITATIVE-ANALYSIS | CANCER | STAGING SYSTEM | ONCOLOGY | DNA | EXPRESSION | Nasopharyngeal Neoplasms - genetics | Carcinoma | Herpesvirus 4, Human - genetics | Prognosis | Follow-Up Studies | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Nasopharyngeal Neoplasms - virology | Neoplasm Recurrence, Local - virology | Male | Chemoradiotherapy | Viral Load | Young Adult | Epstein-Barr Virus Infections - therapy | Nasopharyngeal Neoplasms - blood | Epstein-Barr Virus Infections - genetics | Adult | Female | Epstein-Barr Virus Infections - blood | Nasopharyngeal Carcinoma | Epstein-Barr Virus Infections - virology | Neoplasm Invasiveness | Nasopharyngeal Neoplasms - therapy | Neoplasm Recurrence, Local - therapy | Lymphatic Metastasis | Reverse Transcriptase Polymerase Chain Reaction | Biomarkers, Tumor - blood | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Adolescent | Neoplasm Recurrence, Local - genetics | Aged | Biomarkers, Tumor - genetics | MicroRNAs - blood | MicroRNAs - genetics | Neoplasm Staging | Proteins | Care and treatment | MicroRNA | Analysis | Diagnosis | Biological markers | Cancer | Biomarkers | Radiation therapy | Throat cancer | Medical diagnosis | MicroRNAs | Index Medicus
Journal Article
The Journal of Pathology, ISSN 0022-3417, 06/2016, Volume 239, Issue 2, pp. 186 - 196
Journal Article