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Journal of Clinical Investigation, ISSN 0021-9738, 12/2009, Volume 119, Issue 12, pp. 3626 - 3636
The polycomb group protein B lymphoma Mo-MLV insertion region 1 homolog (Bmi-1) is dysregulated in various cancers, and its upregulation strongly correlates... 
MEDICINE, RESEARCH & EXPERIMENTAL | BREAST-CANCER CELLS | DEVELOPMENTAL REGULATORS | CELLULAR MEMORY | E-CADHERIN EXPRESSION | HEMATOPOIETIC STEM-CELLS | PROSTATE-CANCER | MYC TRANSGENIC MICE | SELF-RENEWAL | NF-KAPPA-B | TRANSCRIPTION FACTOR | Nasopharyngeal Neoplasms - genetics | Neoplasm Transplantation | Nasopharyngeal Neoplasms - metabolism | Epithelial Cells - metabolism | Cadherins - metabolism | Humans | Glycogen Synthase Kinase 3 beta | Transplantation, Heterologous | Phosphatidylinositol 3-Kinases - metabolism | Mesoderm - cytology | Repressor Proteins - antagonists & inhibitors | Nasopharyngeal Neoplasms - pathology | Cadherins - genetics | Epithelial Cells - cytology | Nuclear Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | Nasopharyngeal Neoplasms - etiology | Snail Family Transcription Factors | Nasopharynx - metabolism | Repressor Proteins - metabolism | Proto-Oncogene Proteins - metabolism | PTEN Phosphohydrolase - genetics | Proto-Oncogene Proteins - antagonists & inhibitors | Signal Transduction | Neoplasm Invasiveness | Down-Regulation | Gene Silencing | PTEN Phosphohydrolase - metabolism | Repressor Proteins - genetics | Nuclear Proteins - metabolism | Proto-Oncogene Proteins - genetics | Glycogen Synthase Kinase 3 - metabolism | Transcription Factors - metabolism | Animals | Polycomb Repressive Complex 1 | Mice, Nude | Nuclear Proteins - antagonists & inhibitors | Cell Line, Tumor | Mesoderm - metabolism | Mice | Nasopharynx - cytology | Chromatin | Care and treatment | Lymphomas | Research | Analysis | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
BMC Microbiology, ISSN 1471-2180, 03/2018, Volume 18, Issue 1, pp. 23 - 23
Background: Nonencapsulated Streptococcus pneumoniae bacteria are successful colonizers of the human nasopharynx and often possess genes aliB-like ORF 1 and 2... 
aliB-like ORF 2 | Nonencapsulated | Proteome | Peptide | Transcriptome | Streptococcus pneumoniae | MICROBIOLOGY | COLONIZATION | VIRULENCE | GENOME | MENINGITIS | GENE | DISEASE | SEQUENCE | NONENCAPSULATED STREPTOCOCCUS-PNEUMONIAE | EXPRESSION | BIOFILM FORMATION | Index Medicus
Journal Article
Proceedings of the National Academy of Sciences, ISSN 0027-8424, 12/2012, Volume 109, Issue 50, pp. E3473 - E3482
Undifferentiated nasopharyngeal carcinomas (NPCs) are commonly present with latent EBV infection. However, events regulating EBV infection at early stages of... 
Viral persistence | Epstein-Barr virus | episome | MULTIDISCIPLINARY SCIENCES | viral persistence | HOST SHUTOFF | G/G PHASE | PATHOGENESIS | ARREST | REPLICATION | IN-VIVO | DIFFERENTIATION | CARCINOMA | EXPRESSION | EPSTEIN-BARR-VIRUS | Cyclin D1 - metabolism | Nasopharyngeal Neoplasms - genetics | Precancerous Conditions - etiology | Nasopharyngeal Neoplasms - metabolism | Epithelial Cells - metabolism | Herpesvirus 4, Human - genetics | Humans | Precancerous Conditions - metabolism | Nasopharyngeal Neoplasms - pathology | Telomerase - genetics | Cellular Senescence | Base Sequence | Nasopharynx - virology | Genes, Viral | Epstein-Barr Virus Infections - genetics | Precancerous Conditions - pathology | Telomerase - metabolism | Cell Differentiation | Herpesvirus 4, Human - pathogenicity | Nasopharyngeal Neoplasms - etiology | Nasopharynx - pathology | Nasopharynx - metabolism | Gene Expression | Epstein-Barr Virus Infections - virology | Signal Transduction | Cells, Cultured | Genes, bcl-1 | Epithelial Cells - pathology | Precancerous Conditions - genetics | Cell Cycle | Cyclin D1 - genetics | Cell Transformation, Neoplastic | Epithelial Cells - virology | Cell Line, Tumor | Epstein-Barr Virus Infections - complications | DNA, Viral - genetics | Epstein-Barr Virus Infections - metabolism | Cell Transformation, Viral | Cell growth | Pathogenesis | Telomerase | Viral infections | Tumors | Index Medicus | Biological Sciences | PNAS Plus
Journal Article
PLoS Pathogens, ISSN 1553-7366, 07/2013, Volume 9, Issue 7, pp. e1003509 - e1003509
Neisseria meningitidis (Nme) asymptomatically colonizes the human nasopharynx, yet can initiate rapidly-progressing sepsis and meningitis in rare instances.... 
OPA | SEROGROUP-B | MICROBIOLOGY | GONORRHOEAE | VIROLOGY | EPITHELIAL-CELLS | ADHESION MOLECULE | ENDOTHELIAL-CELLS | MOUSE MODEL | PHASE VARIATION | CARCINOEMBRYONIC ANTIGEN FAMILY | MENINGOCOCCAL DISEASE | PARASITOLOGY | Adaptation, Physiological | Meningococcal Infections - immunology | Cell Adhesion Molecules - genetics | Adhesins, Bacterial - genetics | Humans | Immunity, Mucosal | Meningococcal Infections - microbiology | Antigens, CD - genetics | Antigens, CD - metabolism | Respiratory Mucosa - pathology | Respiratory Tract Infections - microbiology | Adhesins, Bacterial - metabolism | Neisseria meningitidis - immunology | Respiratory Mucosa - microbiology | Protein Isoforms - metabolism | Respiratory Mucosa - immunology | Escherichia coli - metabolism | Neisseria meningitidis - growth & development | Neutrophils - microbiology | Nasopharynx - microbiology | Nasopharynx - pathology | Neutrophils - metabolism | Nasopharynx - metabolism | Neutrophils - pathology | Respiratory Tract Infections - pathology | Recombinant Proteins - metabolism | Respiratory Tract Infections - metabolism | Cells, Cultured | Neutrophils - immunology | Mice, Transgenic | Microbial Viability | Cell Adhesion Molecules - metabolism | Bacterial Adhesion | Animals | Meningococcal Infections - metabolism | Nasopharynx - immunology | Respiratory Tract Infections - immunology | Mice | HeLa Cells | Mutation | Respiratory Mucosa - metabolism | Protein Isoforms - genetics | Physiological aspects | Host-parasite relationships | Neisseria meningitidis | Nasopharynx | Research | Health aspects | Index Medicus | Proteins | Medical research | Rodents | Mortality | Meningitis | Software | Vaccines
Journal Article
British Journal of Cancer, ISSN 0007-0920, 01/2018, Volume 118, Issue 2, pp. 233 - 247
Background: Bactericidal/Permeability-increasing-fold-containing family B member 1 (BPIFB1, previously termed LPLUNC1) is highly expressed in the nasopharynx,... 
CELLS | nasopharyngeal carcinoma | PROTEIN | VIRUS | VITRONECTIN | EPITHELIAL-MESENCHYMAL TRANSITION | VTN | BPIFB1 | VIMENTIN | ONCOLOGY | metastasis | INTEGRINS | POOR-PROGNOSIS | NASAL EPITHELIUM | LPLUNC1 | VIM | EXPRESSION | Nasopharyngeal Neoplasms - metabolism | Autoantigens - metabolism | Autoantigens - biosynthesis | Vimentin - metabolism | Humans | Lung Neoplasms - metabolism | Male | Vitronectin - antagonists & inhibitors | Cell Movement - physiology | MAP Kinase Signaling System | Nasopharyngeal Neoplasms - pathology | Lung Neoplasms - secondary | src-Family Kinases - metabolism | Focal Adhesion Kinase 1 - metabolism | Vimentin - biosynthesis | Neoplasm Invasiveness | Nasopharyngeal Carcinoma - metabolism | Vitronectin - metabolism | Animals | Proteins - metabolism | Mice, Nude | Nasopharyngeal Carcinoma - pathology | Cell Line, Tumor | Mice | Vitronectin - biosynthesis | Vimentin - antagonists & inhibitors | Vimentin | Immunohistochemistry | Immunoprecipitation | Mesenchyme | Lung | Vitronectin | Nasopharynx | Metastasis | Western blotting | Metastases | Cell adhesion & migration | Proteins | Nasopharyngeal carcinoma | Signal transduction | Inhibition | Extracellular signal-regulated kinase | Mass spectroscopy | Permeability | Signaling | Molecular modelling | In vivo methods and tests | Focal adhesion kinase | Immunofluorescence | Mass spectrometry | Cell migration | Index Medicus | Molecular Diagnostics
Journal Article
PLoS ONE, ISSN 1932-6203, 08/2015, Volume 10, Issue 8, pp. e0134896 - e0134896
Oxidative stress is thought to contribute to cancer development. Epstein-Barr virus (EBV) and its encoded oncoprotein, latent membrane protein 1 (LMP1), are... 
GLYCOLYSIS | ACTIVATION | METASTASIS | METABOLISM | MULTIDISCIPLINARY SCIENCES | PROSTATE-CANCER | C-MYC | RECEPTOR | PROLIFERATION | CARCINOMA | PROGRESSION | Immunohistochemistry | Nasopharyngeal Neoplasms - genetics | Nasopharyngeal Neoplasms - metabolism | Viral Matrix Proteins - genetics | Carcinoma | Epithelial Cells - metabolism | Herpesvirus 4, Human - genetics | Reactive Oxygen Species - metabolism | Humans | Gene Expression Regulation, Neoplastic | NADPH Oxidases - metabolism | Nasopharyngeal Neoplasms - virology | Cell Survival - genetics | Immunoblotting | JNK Mitogen-Activated Protein Kinases - metabolism | Phosphatidylinositol 3-Kinases - metabolism | Cell Transformation, Neoplastic - genetics | Nasopharynx - virology | NADPH Oxidases - genetics | Viral Matrix Proteins - metabolism | Proto-Oncogene Proteins c-akt - metabolism | Nasopharynx - pathology | Nasopharynx - metabolism | Cell Line | Cell Survival - drug effects | Nasopharyngeal Carcinoma | Signal Transduction | Herpesvirus 4, Human - physiology | NADPH Oxidases - antagonists & inhibitors | Enzyme Inhibitors - pharmacology | Epithelial Cells - pathology | Onium Compounds - pharmacology | Reverse Transcriptase Polymerase Chain Reaction | Cell Transformation, Neoplastic - metabolism | Host-Pathogen Interactions - genetics | Epithelial Cells - virology | Cell Line, Tumor | Glycolysis | Herpesvirus 4, Human - metabolism | Reactive oxygen species | Physiological aspects | Oxygen consumption | Epstein-Barr virus | Cellular signal transduction | Research | Burkitt's lymphoma | Flow cytometry | Oxidative stress | Transformation | Transcription factors | Laboratories | Oxidase | Cytotoxicity | Viruses | Oncology | AKT protein | Kinases | NAD(P)H oxidase | Proteins | Nasopharyngeal carcinoma | Coding | Tumor necrosis factor-TNF | c-Jun protein | JNK protein | Metabolism | Lymphoma | 1-Phosphatidylinositol 3-kinase | Membrane proteins | NAD | Medicine | Inhibitors | Collaboration | Cell lines | Transformations | Cancer | Apoptosis | Latent membrane protein 1 | Tumors | Index Medicus
Journal Article
Scientific Reports, ISSN 2045-2322, 12/2016, Volume 6, Issue 1, pp. 38094 - 38094
Journal Article
The Journal of Pathology, ISSN 0022-3417, 10/2015, Volume 237, Issue 2, pp. 238 - 248
Non‐keratinizing nasopharyngeal carcinoma ( NPC ) is closely associated with Epstein–Barr virus ( EBV ) infection. The EBV ‐encoded latent membrane protein 1 (... 
LMP1 | nasopharyngeal carcinoma | Epstein–Barr virus | glycolysis | FGFR1 | Epstein-Barr virus | CANCER-CELLS | TYROSINE PHOSPHORYLATION | PROLIFERATION | PATHOLOGY | METABOLISM | ONCOLOGY | HYPOXIA-INDUCIBLE FACTOR-1-ALPHA | ROLES | GROWTH | GENE-EXPRESSION | LATENT MEMBRANE-PROTEIN-1 | CARCINOMA | Nasopharyngeal Neoplasms - genetics | Nasopharyngeal Neoplasms - metabolism | Phosphorylation | Viral Matrix Proteins - genetics | Carcinoma | Cell Proliferation | Epithelial Cells - metabolism | Herpesvirus 4, Human - genetics | Cell Transformation, Viral - drug effects | Humans | Gene Expression Regulation, Neoplastic | Nasopharyngeal Neoplasms - virology | Receptor, Fibroblast Growth Factor, Type 1 - metabolism | Receptor, Fibroblast Growth Factor, Type 1 - genetics | Glycolysis - drug effects | Nasopharyngeal Neoplasms - pathology | Time Factors | Nasopharynx - virology | Fibroblast Growth Factor 2 - metabolism | Viral Matrix Proteins - metabolism | Herpesvirus 4, Human - pathogenicity | Nasopharynx - pathology | Nasopharynx - metabolism | Nasopharyngeal Carcinoma | Neoplasm Invasiveness | Epithelial Cells - pathology | Receptor, Fibroblast Growth Factor, Type 1 - antagonists & inhibitors | Host-Pathogen Interactions | Signal Transduction - drug effects | Epithelial Cells - virology | Cell Line, Tumor | Herpesvirus 4, Human - metabolism | Cell Movement | Immunohistochemistry | Lactates | Glucose metabolism | Analysis | Physiological aspects | Cellular signal transduction | Fibroblast growth factors | Glucose | Health aspects | Dextrose | Glutamine | Index Medicus
Journal Article
Cancer Research, ISSN 0008-5472, 07/2009, Volume 69, Issue 14, pp. 5734 - 5742
Journal Article
Journal Article