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Science, ISSN 0036-8075, 5/2013, Volume 340, Issue 6135, pp. 968 - 971
Journal Article
Circulation, ISSN 0009-7322, 12/2011, Volume 124, Issue 25, pp. 2882 - 2891
Background-In vitro studies suggest that phosphorylation of titin reduces myocyte/myofiber stiffness. Titin can be phosphorylated by cGMP-activated protein... 
Cyclic GMP-dependent protein kinases | Sildenafil | brain | Natriuretic peptide | Heart failure, diastolic | heart failure, diastolic | CARDIAC & CARDIOVASCULAR SYSTEMS | HEART-FAILURE | PROTEIN-KINASE-I | cyclic GMP-dependent protein kinases | RELAXATION | PRESERVED EJECTION FRACTION | DILATED CARDIOMYOPATHY | sildenafil | RAT CARDIAC MYOCYTES | PASSIVE STIFFNESS | NITRIC-OXIDE | PERIPHERAL VASCULAR DISEASE | HEMODYNAMIC-RESPONSES | natriuretic peptide, brain | LEFT-VENTRICULAR FUNCTION | Protein Kinases - metabolism | Connectin | Age Factors | Hypertension - drug therapy | Natriuretic Peptide, Brain - pharmacology | Sulfones - pharmacology | Sildenafil Citrate | Compliance - drug effects | Ventricular Pressure - physiology | Muscle Proteins - metabolism | Ventricular Function, Left - physiology | Diastole - drug effects | Phosphorylation - drug effects | Vasodilator Agents - pharmacology | Purines - pharmacology | Sarcomeres - metabolism | Ventricular Function, Left - drug effects | Ventricular Pressure - drug effects | Diastole - physiology | Piperazines - pharmacology | Hypertension - pathology | Hypertension - physiopathology | Myocytes, Cardiac - pathology | Animals | Myocytes, Cardiac - drug effects | Aging - physiology | Cyclic GMP - metabolism | Biopsy | Myocytes, Cardiac - physiology | Dogs | Heart failure | Care and treatment | Patient outcomes | Dosage and administration | Research | Protein kinases | Natriuretic peptides
Journal Article
Journal Article
The Journal of pharmacology and experimental therapeutics, ISSN 0022-3565, 2014, Volume 350, Issue 3, pp. 681 - 690
Journal Article
American journal of physiology. Regulatory, integrative and comparative physiology, ISSN 0363-6119, 03/2018, Volume 314, Issue 3, pp. R407 - R414
Journal Article
Journal of Molecular and Cellular Cardiology, ISSN 0022-2828, 2012, Volume 52, Issue 5, pp. 1122 - 1134
Abstract Natriuretic peptides (NPs) are best known for their ability to regulate blood vessel tone and kidney function whereas their electrophysiological... 
Cardiovascular | Natriuretic peptide receptors | Sinoatrial node | Electrocardiography | Action potential | Ion channels | Natriuretic peptides | Phosphodiesterase | CARDIAC & CARDIOVASCULAR SYSTEMS | NULL MUTANT MICE | PACEMAKER ACTIVITY | PHOSPHODIESTERASE ACTIVITY | CARDIAC MYOCYTES | DEPENDENT PROTEIN-KINASE | FUNCTIONAL ROLES | CELL BIOLOGY | SIGNAL-TRANSDUCTION | CA2+ CURRENT | CYCLIC-GMP | NPR-C | Atrial Function | Phosphodiesterase 3 Inhibitors - pharmacology | Receptors, Atrial Natriuretic Factor - agonists | Male | Peptide Fragments - pharmacology | Electric Conductivity | Natriuretic Peptide, C-Type - physiology | Natriuretic Peptide, Brain - pharmacology | Natriuretic Peptide, Brain - physiology | Action Potentials | Heart Rate - drug effects | Atrial Natriuretic Factor - pharmacology | Natriuretic Peptide, C-Type - pharmacology | Milrinone - pharmacology | Tetrahydroisoquinolines - pharmacology | Heart Atria - cytology | Receptors, Atrial Natriuretic Factor - metabolism | Sinoatrial Node - physiology | Mice, Inbred C57BL | Adrenergic beta-Agonists - pharmacology | Sinoatrial Node - cytology | Guanylate Cyclase - metabolism | Stimulation, Chemical | Mice, Knockout | Patch-Clamp Techniques | Animals | Myocytes, Cardiac - drug effects | Myocytes, Cardiac - physiology | Isoproterenol - pharmacology | Myocytes, Cardiac - metabolism | Receptors, Atrial Natriuretic Factor - genetics | Mice | In Vitro Techniques | Heart beat | Peptides | Gene expression | Electrocardiogram
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 03/2004, Volume 94, Issue 4, pp. 453 - 461
Journal Article
Hypertension, ISSN 0194-911X, 07/2015, Volume 66, Issue 1, pp. 190 - 198
Elevated B-type natriuretic peptide (BNP) regulates cGMP-phosphodiesterase activity. Its elevation is regarded as an early compensatory response to cardiac... 
synaptic transmission | calcium | natriuretic peptide, brain | sympathetic nervous system | SYSTEM | CYCLIC-NUCLEOTIDE PHOSPHODIESTERASES | RECEPTOR | natriuretic peptide | DEPENDENT PATHWAY | brain | PREHYPERTENSIVE RATS | GUANYLATE-CYCLASE | RESPONSES | INHIBITION | CGMP | PERIPHERAL VASCULAR DISEASE | CONGESTIVE-HEART-FAILURE | Stellate Ganglion - physiology | Cyclic GMP - physiology | Synaptic Transmission - physiology | Sympathetic Nervous System - drug effects | Heart Conduction System - enzymology | Isatin - pharmacology | Male | Natriuretic Peptide, Brain - pharmacology | Natriuretic Peptide, Brain - physiology | Recombinant Fusion Proteins - metabolism | Stellate Ganglion - cytology | Cyclic Nucleotide Phosphodiesterases, Type 2 - genetics | Cyclic GMP-Dependent Protein Kinases - physiology | Sympathetic Nervous System - physiology | Heart Conduction System - physiology | Neurons - physiology | Hypertension - enzymology | Hypertension - genetics | Cyclic Nucleotide Phosphodiesterases, Type 2 - physiology | Heart Rate | Second Messenger Systems - drug effects | Cells, Cultured | Rats | Heart Conduction System - drug effects | Rats, Sprague-Dawley | Stellate Ganglion - drug effects | Hypertension - physiopathology | Receptors, Atrial Natriuretic Factor - physiology | Animals | Calcium Signaling - drug effects | Neurons - enzymology | Receptors, Atrial Natriuretic Factor - drug effects
Journal Article
Journal Article
Circulation Research: Journal of the American Heart Association, ISSN 0009-7330, 12/2002, Volume 91, Issue 12, pp. 1127 - 1134
ABSTRACT—Cardiac fibroblasts (CFs) produce extracellular matrix proteins and participate in the remodeling of the heart. It is unknown if brain natriuretic... 
CGMP | Cardiac fibroblasts | Extracellular matrix | Remodeling | Protein kinase G | remodeling | ACTIVATION | CARDIAC & CARDIOVASCULAR SYSTEMS | STIMULATION | MYOCARDIAL-INFARCTION | cardiac fibroblasts | cGMP | ANGIOTENSIN-II | PROLIFERATION | COLLAGEN-SYNTHESIS | PERIPHERAL VASCULAR DISEASE | protein kinase G | ESSENTIAL-HYPERTENSION | CONGESTIVE-HEART-FAILURE | INHIBITOR | HEMATOLOGY | EXPRESSION | extracellular matrix | Immunohistochemistry | Cyclic GMP - pharmacology | Heart Ventricles - cytology | Proline - metabolism | Natriuretic Peptide, Brain - metabolism | Culture Media, Conditioned - chemistry | Nerve Tissue Proteins - analysis | Natriuretic Peptide, Brain - pharmacology | RNA, Messenger - metabolism | Cyclic GMP-Dependent Protein Kinases - metabolism | Cyclic GMP-Dependent Protein Kinases - antagonists & inhibitors | Cyclic GMP - analogs & derivatives | Radioimmunoassay | Enzyme Induction - drug effects | Collagen - biosynthesis | Fibroblasts - metabolism | Natriuretic Peptide, Brain - genetics | Cells, Cultured | Enzyme Inhibitors - pharmacology | Proline - pharmacokinetics | Nerve Tissue Proteins - metabolism | Animals | Cyclic GMP - metabolism | Signal Transduction - drug effects | Fibroblasts - drug effects | Dogs | Signal Transduction - physiology | Fibroblasts - cytology | Enzyme Induction - physiology | Matrix Metalloproteinases - metabolism | Culture Media, Conditioned - metabolism
Journal Article
Journal Article