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1. Full Text Bezlotoxumab for Prevention of Recurrent Clostridium difficile Infection
by Wilcox, Mark H and Gerding, Dale N and Poxton, Ian R and Kelly, Ciaran and Nathan, Richard and Birch, Thomas and Cornely, Oliver A and Rahav, Galia and Bouza, Emilio and Lee, Christine and Jenkin, Grant and Jensen, Werner and Kim, You-Sun and Yoshida, Junichi and Gabryelski, Lori and Pedley, Alison and Eves, Karen and Tipping, Robert and Guris, Dalya and Kartsonis, Nicholas and Dorr, Mary-Beth and MODIFY II Investigator and MODIFY I Investigator and MODIFY I and MODIFY II Investigators
The New England Journal of Medicine, ISSN 0028-4793, 01/2017, Volume 376, Issue 4, pp. 305 - 317
Bezlotoxumab is human monoclonal antibody against Clostridium difficile toxin B. In two controlled trials, a single intravenous dose of bezlotoxumab, given in... 
MORTALITY | MEDICINE, GENERAL & INTERNAL | TOXIN-B | FIDAXOMICIN | VANCOMYCIN | PROTECTION | STRAIN TYPE | DISEASE | RIBOTYPE | BACTERIAL | MONOCLONAL-ANTIBODIES | Double-Blind Method | Humans | Middle Aged | Antibodies, Monoclonal - adverse effects | Clostridium difficile | Kaplan-Meier Estimate | Antibodies, Monoclonal - therapeutic use | Male | Secondary Prevention | Clostridium Infections - prevention & control | Young Adult | Anti-Bacterial Agents - therapeutic use | Antibodies, Neutralizing - therapeutic use | Adolescent | Intention to Treat Analysis | Aged, 80 and over | Adult | Antibodies, Neutralizing - adverse effects | Female | Aged | Infusions, Intravenous | Drug Therapy, Combination | Care and treatment | Adults | Diagnosis | Clostridium infections | Health aspects | Subpopulations | Bacterial infections | Recurrent infection | Body weight | Clinical trials | Diarrhea | Data processing | Nausea | Preventive medicine | Motivation | Antibiotics | Monoclonal antibodies | Toxins | Drug therapy
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2. Full Text Olanzapine for the Prevention of Chemotherapy-Induced Nausea and Vomiting
by Navari, Rudolph M and Qin, Rui and Ruddy, Kathryn J and Liu, Heshan and Powell, Steven F and Bajaj, Madhuri and Dietrich, Leah and Biggs, David and Lafky, Jacqueline M and Loprinzi, Charles L
The New England Journal of Medicine, ISSN 0028-4793, 07/2016, Volume 375, Issue 2, pp. 134 - 142
The addition of olanzapine to a neurokinin receptor blocker, a serotonin receptor blocker, and dexamethasone markedly improved the control of nausea and... 
TRIAL | MEDICINE, GENERAL & INTERNAL | NETUPITANT | EFFICACY | MODERATELY EMETOGENIC CHEMOTHERAPY | SAFETY | DOUBLE-BLIND | PALONOSETRON | ROLAPITANT | COMBINATION | CANCER | Aprepitant | Olanzapine | Double-Blind Method | Nausea - chemically induced | Humans | Middle Aged | Male | Nausea - prevention & control | Vomiting - chemically induced | Dexamethasone - therapeutic use | Antineoplastic Agents - adverse effects | Antiemetics - therapeutic use | Intention to Treat Analysis | Aged, 80 and over | Adult | Antiemetics - adverse effects | Female | Aged | Benzodiazepines - adverse effects | Drug Therapy, Combination | Benzodiazepines - therapeutic use | Vomiting - prevention & control | Morpholines - therapeutic use | Complications and side effects | Care and treatment | Chemotherapy | Vomiting | Dosage and administration | Nausea | Cancer | Heart attacks | Dexamethasone | Serotonin | Nervous system | Doxorubicin | Cisplatin | Studies | Psychotropic drugs | Cyclophosphamide | Diabetes | Index Medicus | Abridged Index Medicus
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3. Full Text Monoclonal antibodies for migraine prevention progress, but not a panacea
by Loder, Elizabeth W and Robbins, Matthew S
JAMA - Journal of the American Medical Association, ISSN 0098-7484, 05/2018, Volume 319, Issue 19, pp. 1985 - 1987
The article discusses the findings of a study to evaluate the efficacy of fremanezumab as a form of treatment for the prevention of episodic migraine in... 
MEDICINE, GENERAL & INTERNAL | PREVALENCE | EPISODIC MIGRAINE | FREMANEZUMAB | Calcitonin Gene-Related Peptide | Migraine Disorders | Antibodies, Monoclonal | Prevention | Treatment outcome | Care and treatment | Migraine | Analysis | Monoclonal antibodies | Dosage and administration | Disease prevention | Headache | Vomiting | Neurological complications | Nausea
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4. Full Text Prevention of chemotherapy-induced nausea: the role of neurokinin-1 (NK1) receptor antagonists
by Bošnjak, Snežana M and Gralla, Richard J and Schwartzberg, Lee
Supportive Care in Cancer, ISSN 0941-4355, 5/2017, Volume 25, Issue 5, pp. 1661 - 1671
Chemotherapy-induced nausea (CIN) has a significant negative impact on the quality of life of cancer patients. The use of 5-hydroxytryptamine-3 (5-HT3)... 
Chemotherapy-induced nausea and vomiting (CINV) | Pain Medicine | Nursing | Rehabilitation Medicine | Medicine & Public Health | Nursing Research | NK 1 receptor antagonist | Chemotherapy-induced nausea (CIN) | Oncology | Antiemetic guidelines | receptor antagonist | PALONOSETRON NEPA | PHASE-III | ANTIEMETIC THERAPY | INDUCED DELAYED EMESIS | ONCOLOGY | MODERATELY EMETOGENIC CHEMOTHERAPY | HEALTH CARE SCIENCES & SERVICES | DOUBLE-BLIND | REHABILITATION | FIXED-DOSE COMBINATION | RADIOTHERAPY-INDUCED NAUSEA | PLACEBO-CONTROLLED TRIAL | QUALITY-OF-LIFE | NK1 receptor antagonist | Vomiting - chemically induced | Nausea - chemically induced | Antineoplastic Agents - adverse effects | Antiemetics - therapeutic use | Humans | Neurokinin-1 Receptor Antagonists - therapeutic use | Quality of Life - psychology | Prevention | Medical colleges | Chemotherapy | Dexamethasone | Nausea | Patient compliance | Cancer | Side effects | Antagonist drugs | Clinical outcomes | Meta-analysis | Review
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5. Full Text Single-Dose Fosaprepitant for the Prevention of Chemotherapy-Induced Nausea and Vomiting Associated With Cisplatin Therapy: Randomized, Double-Blind Study Protocol—EASE
by Steven Grunberg and Daniel Chua and Anish Maru and José Dinis and Suzanne DeVandry and Judith A. Boice and James S. Hardwick and Elizabeth Beckford and Arlene Taylor and Alexandra Carides and Fausto Roila and Jørn Herrstedt
Journal of Clinical Oncology, ISSN 0732-183X, 04/2011, Volume 29, Issue 11, pp. 1495 - 1501
Purpose Addition of aprepitant, a neurokinin-1 receptor antagonist (NK1RA), to an ondansetron and dexamethasone regimen improves prevention of... 
ORAL NEUROKININ-1 ANTAGONIST | DEXAMETHASONE | ANTIEMETICS | ONCOLOGY | MODERATELY EMETOGENIC CHEMOTHERAPY | CASOPITANT MESYLATE | PATIENTS RECEIVING CISPLATIN | PLACEBO-CONTROLLED TRIAL | DELAYED NAUSEA | MULTIPLE CYCLES | RECEPTOR ANTAGONIST APREPITANT | Dexamethasone - administration & dosage | Double-Blind Method | Drug Administration Schedule | Nausea - chemically induced | Humans | Middle Aged | Morpholines - administration & dosage | Antiemetics - administration & dosage | Ondansetron - administration & dosage | Male | Treatment Outcome | Nausea - prevention & control | Vomiting - chemically induced | Dexamethasone - therapeutic use | Antineoplastic Agents - adverse effects | Ondansetron - therapeutic use | Antiemetics - therapeutic use | Aged, 80 and over | Cisplatin - adverse effects | Adult | Female | Aged | Vomiting - prevention & control | Morpholines - therapeutic use
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6. Full Text Preexposure Chemoprophylaxis for HIV Prevention in Men Who Have Sex with Men
by Grant, Robert M and Lama, Javier R and Anderson, Peter L and McMahan, Vanessa and Liu, Albert Y and Vargas, Lorena and Goicochea, Pedro and Casapía, Martín and Guanira-Carranza, Juan Vicente and Ramirez-Cardich, Maria E and Montoya-Herrera, Orlando and Fernández, Telmo and Veloso, Valdilea G and Buchbinder, Susan P and Chariyalertsak, Suwat and Schechter, Mauro and Bekker, Linda-Gail and Mayer, Kenneth H and Kallás, Esper Georges and Amico, K. Rivet and Mulligan, Kathleen and Bushman, Lane R and Hance, Robert J and Ganoza, Carmela and Defechereux, Patricia and Postle, Brian and Wang, Furong and McConnell, J. Jeff and Zheng, Jia-Hua and Lee, Jeanny and Rooney, James F and Jaffe, Howard S and Martinez, Ana I and Burns, David N and Glidden, David V and iPrEx Study Team
The New England Journal of Medicine, ISSN 0028-4793, 12/2010, Volume 363, Issue 27, pp. 2587 - 2599
In this study, 2499 HIV-seronegative men or transgender women who were at high risk for HIV acquisition were enrolled in a trial of daily emtricitabine plus... 
TRIAL | MEDICINE, GENERAL & INTERNAL | NONOCCUPATIONAL POSTEXPOSURE PROPHYLAXIS | LIMITED KNOWLEDGE | TRANSMISSION | HOMOSEXUAL-MEN | MALE CIRCUMCISION | RISK | INFECTION | MACAQUES | TENOFOVIR | HIV Antibodies - blood | HIV Infections - prevention & control | Follow-Up Studies | Nausea - chemically induced | HIV Infections - epidemiology | Humans | Middle Aged | Drug Resistance, Viral | Male | RNA, Viral - blood | Deoxycytidine - blood | Incidence | Adenine - blood | Tenofovir | Young Adult | Deoxycytidine - therapeutic use | Adenine - adverse effects | Homosexuality, Male | Adenine - therapeutic use | HIV Infections - diagnosis | Adult | Anti-HIV Agents - therapeutic use | Deoxycytidine - adverse effects | Organophosphonates - blood | Anti-HIV Agents - blood | Drug Therapy, Combination | Emtricitabine | Adenine - analogs & derivatives | Transsexualism | Organophosphonates - therapeutic use | Administration, Oral | Anti-HIV Agents - adverse effects | Kaplan-Meier Estimate | Organophosphonates - adverse effects | HIV - isolation & purification | HIV Seropositivity - diagnosis | Adolescent | HIV - genetics | Patient Compliance | Deoxycytidine - analogs & derivatives | Usage | Transgender people | Diagnosis | Drug therapy | Health aspects | HIV infection | Mens health | Acquired immune deficiency syndrome--AIDS | Human immunodeficiency virus--HIV | Alcohol use
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7. Full Text Guideline update for MASCC and ESMO in the prevention of chemotherapy-and radiotherapy-induced nausea and vomiting: Results of the Perugia consensus conference
by Roila, F and Herrstedt, J and Aapro, M and Gralla, R.J and Einhorn, L.H and Ballatori, E and Bria, E and Clark-Snow, R.A and Espersen, B.T and Feyer, P and Grunberg, S.M and Hesketh, P.J and Jordan, K and Kris, M.G and Maranzano, E and Molassiotis, A and Morrow, G and Olver, I and Rapoport, B.L and Rittenberg, C and Saito, M and Tonato, M and Warr, D and ESMO MASCC Guidelines Working Grp and ESMO/MASCC Guidelines Working Group and On behalf of the ESMO/MASCC Guidelines Working Group
Annals of Oncology, ISSN 0923-7534, 05/2010, Volume 21, Issue 5, pp. v232 - v243
BREAST-CANCER | ONCOLOGY | MODERATELY EMETOGENIC CHEMOTHERAPY | CASOPITANT MESYLATE | PHASE-III | DOUBLE-BLIND | APREPITANT | PLACEBO-CONTROLLED TRIAL | HIGH-DOSE CISPLATIN | NEUROKININ-1 RECEPTOR ANTAGONIST | ACUTE EMESIS | Nausea - prevention & control | Vomiting - chemically induced | Nausea - chemically induced | Humans | Vomiting - drug therapy | Nausea - drug therapy | Vomiting - prevention & control | Practice Guidelines as Topic
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8. Full Text Low-dose droperidol (≤1 mg or ≤15 μg kg−1) for the prevention of postoperative nausea and vomiting in adults: quantitative systematic review of randomised controlled trials
by Schaub, Isabelle and Lysakowski, Christopher and Elia, Nadia and Tramèr, Martin R
European Journal of Anaesthesiology, ISSN 0265-0215, 06/2012, Volume 29, Issue 6, pp. 286 - 294
CONTEXTDroperidol is widely used for the prevention of postoperative nausea and vomiting (PONV) in European countries. It is unclear how efficacious low-dose... 
Nausea | Vomiting | Droperidol | Emesis | INTERVAL PROLONGATION | PLACEBO | droperidol | EFFICACY | ONDANSETRON | emesis | QTC INTERVAL | METOCLOPRAMIDE | COMBINATION | GENERAL-ANESTHESIA | nausea | PROPHYLACTIC ANTIEMETIC THERAPY | ANESTHESIOLOGY | LAPAROSCOPY | vomiting | Droperidol - adverse effects | Droperidol - therapeutic use | Humans | Antiemetics - administration & dosage | Treatment Outcome | Statistics as Topic | Postoperative Nausea and Vomiting - prevention & control | Randomized Controlled Trials as Topic | Dose-Response Relationship, Drug | Antiemetics - therapeutic use | Adult | Antiemetics - adverse effects | Droperidol - administration & dosage | Index Medicus
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