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Nature, ISSN 0028-0836, 03/2008, Volume 452, Issue 7184, pp. 176 - 180
Anthelmintic resistance in human and animal pathogenic helminths has been spreading in prevalence and severity to a point where multidrug resistance against... 
HAEMONCHUS-CONTORTUS | CAENORHABDITIS-ELEGANS | HELMINTHS | EFFICACY | MULTIDISCIPLINARY SCIENCES | IVERMECTIN | ACETYLCHOLINE-RECEPTOR SUBUNITS | GHANA | LIVESTOCK | Parasitic Diseases, Animal - parasitology | Aminoacetonitrile - analogs & derivatives | Caenorhabditis elegans Proteins - chemistry | Sheep Diseases - parasitology | Caenorhabditis elegans Proteins - metabolism | Molecular Sequence Data | Sheep - parasitology | Cattle Diseases - parasitology | Receptors, Nicotinic - chemistry | Cattle | Larva - drug effects | Aging | Cattle Diseases - drug therapy | Larva - genetics | Anthelmintics - pharmacokinetics | Amino Acid Sequence | Receptors, Nicotinic - metabolism | Caenorhabditis elegans - metabolism | Caenorhabditis elegans - genetics | Anthelmintics - chemistry | Sheep Diseases - drug therapy | Nematoda - physiology | Nematoda - drug effects | Parasitic Diseases, Animal - drug therapy | Anthelmintics - classification | Drug Resistance - genetics | Nematoda - genetics | Animals | Caenorhabditis elegans - drug effects | Aminoacetonitrile - adverse effects | Aminoacetonitrile - pharmacokinetics | Anthelmintics - pharmacology | Aminoacetonitrile - pharmacology | Caenorhabditis elegans Proteins - genetics | Receptors, Nicotinic - genetics | Pathology | Livestock | Drug resistance | Drug therapy | Worms | Index Medicus
Journal Article
Plant Biotechnology Journal, ISSN 1467-7644, 02/2016, Volume 14, Issue 2, pp. 592 - 602
Summary Myo‐inositol‐1‐phosphate synthase (MIPS) is a key rate limiting enzyme in myo‐inositol biosynthesis. The MIPS gene has been shown to improve tolerance... 
IbMIPS1 | sweet potato | stem nematode resistance | salt and drought tolerance | Salt and drought tolerance | Stem nematode resistance | Sweet potato | COARCTATA ROXB. TATEOKA | PLANT | IPOMOEA-BATATAS | SEED DEVELOPMENT | PLANT SCIENCES | BIOTECHNOLOGY & APPLIED MICROBIOLOGY | INOSITOL 1-PHOSPHATE SYNTHASE | HYDROGEN-PEROXIDE | PHOSPHATIDIC-ACID | MOLECULAR-CLONING | ABSCISIC-ACID | STRESS TOLERANCE | Genes, Plant | Plant Stems - parasitology | Sodium Chloride - pharmacology | Adaptation, Physiological - drug effects | Salt-Tolerance - drug effects | Ipomoea batatas - enzymology | Adaptation, Physiological - genetics | Droughts | Plants, Genetically Modified | Salt-Tolerance - genetics | Stress, Physiological - drug effects | Polyethylene Glycols - pharmacology | Disease Resistance - drug effects | Myo-Inositol-1-Phosphate Synthase - genetics | Up-Regulation - genetics | Ipomoea batatas - parasitology | Nematoda - physiology | Nematoda - drug effects | Up-Regulation - drug effects | Abscisic Acid - pharmacology | Animals | Plant Stems - drug effects | Signal Transduction - drug effects | Ipomoea batatas - physiology | Myo-Inositol-1-Phosphate Synthase - metabolism | Plant Diseases - parasitology | Ipomoea batatas - genetics | Phosphates | Lignin | Biotechnology | Inositol | Genetically engineered foods | Genes | Analysis | Physiological aspects | Abscisic acid | Genetic research | Genetic engineering | Nematoda | Food | Stresses | Inositols | Sweet potatoes | Transgenic | Nematodes | Plants (organisms)
Journal Article
Science, ISSN 0036-8075, 1/2005, Volume 307, Issue 5707, pp. 258 - 262
Genetic studies have elucidated mechanisms that regulate aging, but there has been little progress in identifying drugs that delay aging. Here, we report that... 
Anticonvulsants | Pumping | Molecular structure | Developmental biology | Mucosa | Reports | Oviposition | Amyloids | Solar fibrils | Genetic mutation | Worms | MUTANTS | C-ELEGANS | CAENORHABDITIS-ELEGANS | MULTIDISCIPLINARY SCIENCES | ETHOSUXIMIDE | LONG | Longevity - drug effects | Humans | Aging - drug effects | Genes, Helminth | Anticonvulsants - pharmacology | Dose-Response Relationship, Drug | Caenorhabditis elegans - physiology | Lactams - pharmacology | Neurons - physiology | Female | Synaptic Transmission - drug effects | Pharynx - physiology | Trimethadione - therapeutic use | Drug Evaluation, Preclinical | Neurons - drug effects | Disorders of Sex Development | Movement - drug effects | Transcription Factors - physiology | Caenorhabditis elegans - growth & development | Caenorhabditis elegans - genetics | Muscles - physiology | Trimethadione - pharmacology | Ethosuximide - therapeutic use | Anticonvulsants - therapeutic use | Vulva | Transcription Factors - genetics | Aldicarb - pharmacology | Reproduction - drug effects | Animals | Caenorhabditis elegans - drug effects | Muscles - drug effects | Muscles - innervation | Oviposition - drug effects | Epilepsy, Absence - drug therapy | Caenorhabditis elegans Proteins - physiology | Mutation | Pharynx - drug effects | Caenorhabditis elegans Proteins - genetics | Ethosuximide - pharmacology | Forkhead Transcription Factors | Drugs | Usage | Ethosuximide | Aging | Research | Nematoda | Nematodes | Genotype & phenotype
Journal Article
PLoS ONE, ISSN 1932-6203, 04/2017, Volume 12, Issue 4, p. e0176883
The quorum sensing (QS) circuit plays a role in the precise regulation of genes controlling virulence factors and biofilm formation in Pseudomonas aeruginosa.... 
IN-VITRO | TWITCHING MOTILITY | TO-CELL COMMUNICATION | SYNERGISTIC ANTIBACTERIAL EFFICACY | EARLY COMBINATION TREATMENT | MULTIDISCIPLINARY SCIENCES | SUSCEPTIBILITY | IV PILI | CYSTIC-FIBROSIS | LUNG INFECTION | BACTERIAL BIOFILMS | Virulence - drug effects | Prostheses and Implants - microbiology | Pseudomonas aeruginosa - physiology | Interferon-gamma - metabolism | Prosthesis-Related Infections - drug therapy | Dose-Response Relationship, Drug | Pseudomonas Infections - metabolism | Prosthesis-Related Infections - microbiology | Pseudomonas aeruginosa - pathogenicity | Female | Flavonoids - pharmacology | Drug Therapy, Combination | Disease Models, Animal | Biofilms - drug effects | Quorum Sensing - drug effects | Pseudomonas Infections - drug therapy | Interleukin-4 - metabolism | Pseudomonas aeruginosa - drug effects | Pseudomonas Infections - microbiology | Caenorhabditis elegans | Animals | Bacterial Proteins - metabolism | Prosthesis-Related Infections - metabolism | Virulence Factors - metabolism | Anti-Bacterial Agents - pharmacology | Mice, Inbred BALB C | Pseudomonas aeruginosa - ultrastructure | Peritoneum | Usage | Physiological aspects | Pseudomonas aeruginosa | Quorum sensing | Medicine, Chinese | Research | Virulence (Microbiology) | Surgical implants | Motility | Transplants & implants | Genes | Virulence | Inflammatory response | Infections | Drug resistance | Chinese medicine | Bacteria | Life sciences | Elastase | Nosocomial infections | Immune system | Pathogens | Immune response | Mortality | Staphylococcus infections | Cystic fibrosis | Gene expression | Mitigation | Biofilms | Hospitals | Antibiotics | Respiratory diseases | Nematodes | Mice | Infiltration | Interferon | In vitro methods and tests
Journal Article
Journal Article
New Phytologist, ISSN 0028-646X, 8/2015, Volume 207, Issue 3, pp. 778 - 789
Journal Article
PLoS ONE, ISSN 1932-6203, 07/2012, Volume 7, Issue 7, p. e40937
Essentially any behavior in simple and complex animals depends on neuronal network function. Currently, the best-defined system to study neuronal circuits is... 
NERVOUS-SYSTEM | MANIPULATION | AVOIDANCE | MULTIDISCIPLINARY SCIENCES | SYNAPTIC-TRANSMISSION | ASH NEURONS | CHANNELRHODOPSIN-2 | OPTOGENETIC ANALYSIS | OPTICAL INTERROGATION | BEHAVIORS | CIRCUIT | Muscle Cells - drug effects | Optogenetics | Nerve Net - drug effects | Nerve Net - physiology | Cholinergic Neurons - physiology | Caenorhabditis elegans - physiology | Proton Pumps - pharmacology | Light | Neurons - physiology | Nociception - drug effects | Halorhodopsins - pharmacology | Nerve Net - radiation effects | Neurons - drug effects | Motor Neurons - drug effects | Archaeal Proteins - pharmacology | Locomotion - drug effects | Proton Pumps - radiation effects | Motor Neurons - physiology | Touch - drug effects | Cholinergic Neurons - drug effects | Caenorhabditis elegans - radiation effects | Muscle Cells - physiology | Animals | Caenorhabditis elegans - drug effects | Signal Transduction - drug effects | Muscle Cells - radiation effects | Fungal Proteins - pharmacology | Neurons - radiation effects | Neurons | Animal behavior | Nematoda | Membrane proteins | Protons | Bioengineering | Interneurons | Dopamine | Arches | Electrophysiology | Nervous system | Biochemistry | Interdisciplinary aspects | Ashes | Signaling | Microorganisms | Pumps | Neural networks | Rodents | Sensory neurons | Nematodes | Illumination | Life sciences | Behavior | Inhibition | Worms
Journal Article
Journal of Ethnopharmacology, ISSN 0378-8741, 11/2016, Volume 192, pp. 413 - 422
is a medicinal mushroom traditionally used in China for a variety of conditions, including inflammatory and neural diseases. polysaccharides (DiPS) are shown... 
DAF-16/FOXO | Oxidative stress | Mitochondria | Neurodegenerative diseases | Dictyophora indusiata | CHEMISTRY, MEDICINAL | PROTEIN | PROTECTION | NEUROTOXICITY | SKN-1 | CELL-DEATH | PLANT SCIENCES | INHIBITION | INTEGRATIVE & COMPLEMENTARY MEDICINE | DISEASE | PHARMACOLOGY & PHARMACY | DYSFUNCTION | EXTRACT | Neurons - pathology | Reactive Oxygen Species - metabolism | Neurotoxicity Syndromes - genetics | Caenorhabditis elegans Proteins - metabolism | Membrane Potential, Mitochondrial - drug effects | Dose-Response Relationship, Drug | Neuroprotective Agents - pharmacology | Peptides - toxicity | Neurotoxicity Syndromes - pathology | Time Factors | Polysaccharides - isolation & purification | Adenosine Triphosphate - metabolism | Neurons - metabolism | Neurons - drug effects | Superoxide Dismutase - metabolism | Malondialdehyde - metabolism | Caenorhabditis elegans - metabolism | Amyloid beta-Peptides - toxicity | Animals, Genetically Modified | Caenorhabditis elegans - genetics | Neurotoxicity Syndromes - prevention & control | Mitochondria - metabolism | Antioxidants - pharmacology | Mitochondria - drug effects | Mitochondria - pathology | Polysaccharides - pharmacology | Animals | Caenorhabditis elegans - drug effects | Neuroprotective Agents - isolation & purification | Antioxidants - isolation & purification | Neurotoxicity Syndromes - metabolism | Oxidative Stress - drug effects | Nerve Degeneration | Paraquat - toxicity | Caenorhabditis elegans Proteins - genetics | Energy Metabolism - drug effects | Agaricales - chemistry | Antioxidants | Caenorhabditis elegans | Polysaccharides | Drug discovery | Herbicides | Nervous system diseases | Analysis | Superoxide | Genetic engineering | Nematoda
Journal Article