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The Journal of Immunology, ISSN 0022-1767, 12/2008, Volume 181, Issue 11, pp. 8088 - 8095
We have examined CD40-dependent signals in endothelial cells (EC) mediating the expression of vascular endothelial growth factor (VEGF) and VEGF-induced... 
Phosphoproteins - immunology | Inflammation - pathology | RNA, Small Interfering - genetics | Transcriptional Activation - genetics | Humans | Transcriptional Activation - drug effects | Protein Biosynthesis - immunology | Transcriptional Activation - immunology | Promoter Regions, Genetic - drug effects | Vascular Endothelial Growth Factor A - genetics | CD40 Ligand - immunology | Ribosomal Protein S6 Kinases - immunology | Inflammation - metabolism | Phosphorylation - genetics | Adaptor Proteins, Signal Transducing - immunology | Regulatory-Associated Protein of mTOR | CD40 Antigens - genetics | Phosphorylation - immunology | Phosphorylation - drug effects | Proto-Oncogene Proteins c-akt - metabolism | Transcription Factors - immunology | Carrier Proteins - immunology | Fibroblasts - metabolism | Endothelial Cells - metabolism | Carrier Proteins - antagonists & inhibitors | Vascular Endothelial Growth Factor A - immunology | Signal Transduction - genetics | Proto-Oncogene Proteins c-akt - immunology | CD40 Ligand - genetics | Signal Transduction - drug effects | CD40 Ligand - pharmacology | Neoplasms - immunology | Fibroblasts - immunology | Protein Biosynthesis - drug effects | Anti-Bacterial Agents - pharmacology | Mice | TOR Serine-Threonine Kinases | Proteins - antagonists & inhibitors | CD40 Antigens - immunology | Neoplasms - metabolism | Vascular Endothelial Growth Factor A - biosynthesis | Ribosomal Protein S6 Kinases - metabolism | Multiprotein Complexes | Phosphoproteins - metabolism | Promoter Regions, Genetic - genetics | Proto-Oncogene Proteins c-akt - genetics | Mechanistic Target of Rapamycin Complex 1 | Signal Transduction - immunology | CD40 Antigens - metabolism | CD40 Ligand - metabolism | Neoplasms - genetics | RNA, Small Interfering - immunology | Protein Biosynthesis - genetics | Rapamycin-Insensitive Companion of mTOR Protein | Inflammation - immunology | Phosphoproteins - genetics | Transcription Factors - genetics | Mice, SCID | Sirolimus - pharmacology | Proteins - immunology | Endothelial Cells - immunology | Proteins - genetics | Transcription Factors - metabolism | Carrier Proteins - genetics | Animals | Carrier Proteins - metabolism | Proteins - metabolism | Adaptor Proteins, Signal Transducing - genetics | Inflammation - genetics | Promoter Regions, Genetic - immunology | Adaptor Proteins, Signal Transducing - metabolism | Neoplasms - pathology | Ribosomal Protein S6 Kinases - genetics
Journal Article
Blood, ISSN 1528-0020, 01/2008, Volume 111, Issue 2, pp. 750 - 760
We investigated the mechanism by which B lymphocyte stimulator (BLyS)/BAFF, a tumor necrosis factor superfamily ligand, promotes B-cell survival and resistance... 
Life Sciences & Biomedicine | Hematology | Science & Technology | Protein Kinases - genetics | Proto-Oncogene Proteins c-bcl-2 - immunology | Neoplasm Proteins - immunology | Cell Survival - genetics | Glycolysis - drug effects | Glycolysis - genetics | Cell Death - genetics | B-Lymphocytes - pathology | Neoplasm Proteins - genetics | Proto-Oncogene Proteins c-akt - metabolism | B-Lymphocytes - metabolism | Protein-Serine-Threonine Kinases - metabolism | Cell Survival - drug effects | Signal Transduction - genetics | Germinal Center - pathology | Mice, Knockout | B-Cell Activating Factor - metabolism | B-Lymphocytes - immunology | Proto-Oncogene Proteins c-akt - immunology | Signal Transduction - drug effects | Mice | TOR Serine-Threonine Kinases | Protein Kinases - metabolism | Germinal Center - immunology | Atrophy - pathology | Cell Death - immunology | Neoplasm Proteins - metabolism | Proto-Oncogene Proteins c-akt - genetics | Proto-Oncogene Proteins c-bcl-2 - metabolism | Signal Transduction - immunology | Atrophy - genetics | Proto-Oncogene Proteins - immunology | B-Cell Activating Factor - immunology | Cell Death - drug effects | Immunosuppressive Agents - pharmacology | Proto-Oncogene Proteins - metabolism | Cell Size - drug effects | Atrophy - immunology | Protein-Serine-Threonine Kinases - genetics | Proto-Oncogene Proteins - genetics | Cell Survival - immunology | Sirolimus - pharmacology | Animals | Germinal Center - metabolism | Protein Kinases - immunology | B-Cell Activating Factor - genetics | Myeloid Cell Leukemia Sequence 1 Protein | Protein-Serine-Threonine Kinases - immunology | Proto-Oncogene Proteins c-bcl-2 - genetics | Glycolysis - immunology | Immunobiology
Journal Article
Journal Article
The Lancet (British edition), ISSN 0140-6736, 2015, Volume 386, Issue 10008, pp. 2078 - 2088
.... We assessed whether VGX-3100, synthetic plasmids targeting HPV-16 and HPV-18 E6 and E7 proteins, delivered by electroporation, would cause histopathological regression in women with CIN2/3... 
Internal Medicine | Medicine, General & Internal | Life Sciences & Biomedicine | General & Internal Medicine | Science & Technology | Human papillomavirus 18 - immunology | Humans | Papillomavirus E7 Proteins - immunology | Vaccines, DNA - immunology | Cervical Intraepithelial Neoplasia - drug therapy | Human papillomavirus 16 - immunology | Papillomavirus E7 Proteins - genetics | Young Adult | Cancer Vaccines - therapeutic use | Adult | Female | Oncogene Proteins, Viral - genetics | Papillomavirus Infections - virology | Human papillomavirus 18 - genetics | DNA-Binding Proteins - immunology | Papillomavirus Vaccines - therapeutic use | Double-Blind Method | Repressor Proteins - genetics | Treatment Outcome | Uterine Cervical Neoplasms - drug therapy | Vaccines, DNA - therapeutic use | DNA-Binding Proteins - genetics | Cervical Intraepithelial Neoplasia - virology | Cancer Vaccines - immunology | Repressor Proteins - immunology | Papillomavirus Infections - drug therapy | Uterine Cervical Neoplasms - virology | Papillomavirus Vaccines - immunology | Oncogene Proteins, Viral - immunology | Human papillomavirus 16 - genetics | Proteins | Cervix dysplasia | DNA | Clinical trials | Product development | Vaccines | Health aspects | Papillomavirus infections | Medical research | Analysis | Medicine, Experimental | Human papillomavirus | Immunization | Womens health | Immunotherapy | Genomes | Cervical cancer | Deoxyribonucleic acid--DNA
Journal Article
Nature immunology, ISSN 1529-2916, 2007, Volume 8, Issue 8, pp. 856 - 863
Journal Article