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Cancer Cell, ISSN 1535-6108, 2008, Volume 13, Issue 3, pp. 193 - 205
Tumor vasculature is derived from sprouting of local vessels (angiogenesis) and bone marrow (BM)-derived circulating cells (vasculogenesis). By using a model... 
CELLCYCLE | BREAST-CANCER | ENDOTHELIAL PROGENITOR CELLS | RECTAL-CANCER | MAMMARY-TUMORS | ONCOLOGY | HEMATOPOIETIC STEM-CELLS | IN-VIVO | GROWTH-FACTOR | PRECURSOR CELLS | CANCER-THERAPY | RADIATION-THERAPY | CELL BIOLOGY | Myeloid Cells - enzymology | Bone Marrow Cells - enzymology | Neoplasms, Experimental - enzymology | Antineoplastic Agents - therapeutic use | Monocytes - immunology | Subcutaneous Tissue - surgery | Neovascularization, Pathologic - pathology | Neoplasms, Experimental - pathology | Neovascularization, Pathologic - enzymology | Protease Inhibitors - pharmacology | Matrix Metalloproteinase 9 - metabolism | Monocytes - transplantation | Melanoma, Experimental | Stem Cells - enzymology | Time Factors | Matrix Metalloproteinase 9 - genetics | Myeloid Cells - immunology | Bone Marrow Cells - immunology | Bone Marrow Transplantation | Diphosphonates - therapeutic use | Bone Marrow Cells - drug effects | Myeloid Cells - drug effects | Neovascularization, Pathologic - prevention & control | Antineoplastic Agents - pharmacology | Imidazoles - therapeutic use | Protease Inhibitors - therapeutic use | Signal Transduction | Mice, Inbred C57BL | Imidazoles - pharmacology | Matrix Metalloproteinase 9 - deficiency | Neoplasms, Experimental - radiotherapy | Mice, Inbred C3H | Mice, Knockout | Monocytes - drug effects | Monocytes - enzymology | Subcutaneous Tissue - radiation effects | Animals | Subcutaneous Tissue - blood supply | Matrix Metalloproteinase Inhibitors | Myeloid Cells - transplantation | Mice | CD11b Antigen - metabolism | Endothelial Cells - enzymology | Neoplasms, Experimental - drug therapy | Diphosphonates - pharmacology | Neoplasms, Experimental - blood supply | Neovascularization | Nuclear radiation | Analysis | Tumors
Journal Article
Science, ISSN 0036-8075, 7/2011, Volume 333, Issue 6039, pp. 233 - 238
Journal Article
Cancer Research, ISSN 0008-5472, 05/2011, Volume 71, Issue 9, pp. 3364 - 3376
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 08/2013, Volume 123, Issue 8, pp. 3231 - 3242
Journal Article
Cancer Cell, ISSN 1535-6108, 04/2013, Volume 23, Issue 4, pp. 450 - 463
Journal Article
The Journal of Immunology, ISSN 0022-1767, 06/2007, Volume 178, Issue 11, pp. 7405 - 7411
Journal Article
Journal of Clinical Investigation, ISSN 0021-9738, 06/2015, Volume 125, Issue 6, pp. 2293 - 2306
Glutaminase (GLS), which converts glutamine to glutamate, plays a key role in cancer cell metabolism, growth, and proliferation. GLS is being explored as a... 
CANCER-CELLS | MEDICINE, RESEARCH & EXPERIMENTAL | KIDNEY-TYPE GLUTAMINASE | PHOSPHATE-ACTIVATED GLUTAMINASE | MITOCHONDRIAL METABOLISM | AEROBIC GLYCOLYSIS | GROWTH | C-MYC | ACUTE MYELOID-LEUKEMIA | 2-HYDROXYGLUTARATE LEVELS | EXPRESSION | Neoplasm Transplantation | Humans | Gene Expression Regulation, Neoplastic | Mutation, Missense | Carcinoma, Hepatocellular - drug therapy | Heterografts | Cell Transformation, Neoplastic - genetics | Carcinoma, Hepatocellular - genetics | Liver Neoplasms, Experimental - genetics | Liver Neoplasms, Experimental - pathology | Sulfides - pharmacology | Thiadiazoles - pharmacology | Glutaminase - biosynthesis | Mice, Transgenic | Carcinoma, Hepatocellular - enzymology | Cell Transformation, Neoplastic - metabolism | Glutaminase - antagonists & inhibitors | Gene Expression Regulation, Enzymologic | Animals | Liver Neoplasms, Experimental - drug therapy | Carcinoma, Hepatocellular - pathology | Liver Neoplasms, Experimental - enzymology | Mice | Mice, Inbred BALB C | Cell Transformation, Neoplastic - pathology | Glutaminase - genetics | Amino Acid Substitution | Medical research | Enzymes | Colleges & universities | Grants | Glucose | Metabolism | Fatty acids | Proteins | Survival analysis | Cell growth | Software | Lymphomas | Tumorigenesis | Infrared imaging systems | Laboratory animals | Tumors | Cancer | Crystal structure | Index Medicus | Abridged Index Medicus | Oncology | Hepatology
Journal Article
Cancer Research, ISSN 0008-5472, 08/2010, Volume 70, Issue 15, pp. 6139 - 6149
Journal Article
Journal Article
Cancer Discovery, ISSN 2159-8274, 08/2012, Volume 2, Issue 8, pp. 722 - 735
Indoleamine 2,3-dioxygenase (IDO) enzyme inhibitors have entered clinical trials for cancer treatment based on preclinical studies, indicating that they can... 
TUMOR PROGRESSION | DENDRITIC CELLS | K-RAS | ONCOLOGY | ARYL-HYDROCARBON RECEPTOR | INDOLEAMINE 2,3-DIOXYGENASE | IN-VIVO | SUPPRESSOR-CELLS | CHRONIC INFLAMMATION | EXPRESSION | TRYPTOPHAN CATABOLISM | Indoleamine-Pyrrole 2,3,-Dioxygenase - genetics | Indoleamine-Pyrrole 2,3,-Dioxygenase - metabolism | Adenocarcinoma - pathology | Adenocarcinoma of Lung | Humans | Lung Neoplasms - pathology | Indoleamine-Pyrrole 2,3,-Dioxygenase - deficiency | Neovascularization, Pathologic - enzymology | Neoplasm Metastasis | Lung Neoplasms - secondary | Cell Transformation, Neoplastic - genetics | Inflammation - drug therapy | U937 Cells | Mammary Neoplasms, Experimental - pathology | Adenocarcinoma - genetics | Mammary Neoplasms, Experimental - enzymology | Lung Neoplasms - blood supply | Lung Neoplasms - genetics | Lung Neoplasms - enzymology | Mice, Inbred C57BL | Adenocarcinoma - enzymology | Kaplan-Meier Estimate | Mice, Transgenic | Cell Transformation, Neoplastic - metabolism | Disease Progression | Adenocarcinoma - blood supply | Animals | Survival Analysis | HL-60 Cells | Interleukin-6 - biosynthesis | Mice | Mice, Inbred BALB C | Cell Transformation, Neoplastic - pathology | Genes, ras | Inflammation - enzymology | Indoleamine-Pyrrole 2,3,-Dioxygenase - antagonists & inhibitors | lung cancer | mouse models | breast cancer metastasis | interleukin 6 (IL-6) | Kras | vascularization | immune escape | myeloid-derived suppressor cells (MDSC)
Journal Article
Cell, ISSN 0092-8674, 2007, Volume 130, Issue 6, pp. 1120 - 1133
Coordination of cell proliferation and cell death is essential to attain proper organ size during development and for maintaining tissue homeostasis throughout... 
DEVBIO | SIGNALING | YES-ASSOCIATED PROTEIN | WW | APOPTOSIS | DOMAIN | BIOCHEMISTRY & MOLECULAR BIOLOGY | TRANSCRIPTION | TUMOR-SUPPRESSOR | YAP | MICE | CELL | CANCER | CELL BIOLOGY | Protein Kinases - metabolism | Phosphorylation | Cell Proliferation | Large Neutral Amino Acid-Transporter 1 - metabolism | Humans | Liver Neoplasms, Experimental - chemically induced | Homeostasis | Cytoplasm - metabolism | Drosophila Proteins - metabolism | Doxorubicin | Drosophila - enzymology | Liver Neoplasms, Experimental - metabolism | Cell Nucleus - metabolism | Transfection | Trans-Activators - genetics | Active Transport, Cell Nucleus | Liver Neoplasms, Experimental - pathology | Nuclear Proteins - genetics | Protein-Serine-Threonine Kinases - metabolism | Drosophila - genetics | Cell Line | Mammals - metabolism | Mammals - growth & development | Signal Transduction | Mice, Inbred C57BL | Cell Cycle Proteins - metabolism | Protein-Serine-Threonine Kinases - genetics | Intracellular Signaling Peptides and Proteins | Organ Size | Drosophila - cytology | Mice, Transgenic | Nuclear Proteins - metabolism | Transcription Factors - genetics | Serine - metabolism | Transcription Factors - metabolism | Animals | Liver Neoplasms, Experimental - enzymology | Trans-Activators - metabolism | Drosophila - growth & development | Mice | Drosophila - metabolism | Drosophila Proteins - genetics | Mutation | Adaptor Proteins, Signal Transducing - metabolism | Apoptosis | Drosophila | Knowledge-based systems
Journal Article