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Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2016, Volume 18, Issue 1, pp. 75 - 87
Summary Background Poly(ADP-ribose) polymerase (PARP) inhibitors have activity in ovarian carcinomas with homologous recombination deficiency. Along with BRCA1... 
Hematology, Oncology and Palliative Medicine | BRCA MUTATION | POLY(ADP-RIBOSE) POLYMERASE | RANDOMIZED PHASE-2 | ONCOLOGY | HOMOLOGOUS RECOMBINATION DEFICIENCY | MUTANT-CELLS | PROSTATE-CANCER | INHIBITORS | DNA-REPAIR | NEGATIVE BREAST-CANCER | GENOMIC LOSS | Prognosis | Prospective Studies | Follow-Up Studies | Humans | Middle Aged | Ovarian Neoplasms - pathology | Salvage Therapy | Neoplasm Recurrence, Local - drug therapy | Germ-Line Mutation - genetics | Neoplasm Recurrence, Local - pathology | Ovarian Neoplasms - genetics | Neoplasms, Glandular and Epithelial - genetics | Peritoneal Neoplasms - drug therapy | Fallopian Tube Neoplasms - genetics | Female | Antineoplastic Agents - pharmacology | Poly(ADP-ribose) Polymerases - chemistry | Ovarian Neoplasms - drug therapy | Platinum - pharmacology | Fallopian Tube Neoplasms - drug therapy | Peritoneal Neoplasms - pathology | Neoplasms, Glandular and Epithelial - pathology | Fallopian Tube Neoplasms - pathology | Survival Rate | Poly(ADP-ribose) Polymerase Inhibitors - therapeutic use | BRCA1 Protein - genetics | International Agencies | Peritoneal Neoplasms - genetics | Neoplasms, Glandular and Epithelial - drug therapy | Carcinoma, Ovarian Epithelial | Indoles - therapeutic use | Neoplasm Recurrence, Local - genetics | Aged | Neoplasm Staging | BRCA2 Protein - genetics | Drug Resistance, Neoplasm - drug effects | Sugars | Monosaccharides | Ovarian cancer | Analysis | Carcinoma | Cancer | Index Medicus
Journal Article
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2014, Volume 15, Issue 11, pp. 1207 - 1214
Summary Background Olaparib is a poly(ADP-ribose) polymerase inhibitor and cediranib is an anti-angiogenic agent with activity against VEGF receptor (VEGFR) 1,... 
Hematology, Oncology and Palliative Medicine | TRIAL | POLY(ADP-RIBOSE) POLYMERASE | ONCOLOGY | BEVACIZUMAB | DOWN-REGULATION | FALLOPIAN-TUBE | OPEN-LABEL | EPITHELIAL OVARIAN | MAINTENANCE THERAPY | PRIMARY PERITONEAL | NEGATIVE BREAST-CANCER | Piperazines - administration & dosage | Confidence Intervals | Follow-Up Studies | Humans | Middle Aged | Ovarian Neoplasms - pathology | Neoplasm Recurrence, Local - drug therapy | Ovarian Neoplasms - mortality | Neoplasm Recurrence, Local - mortality | Cisplatin - administration & dosage | Dose-Response Relationship, Drug | Neoplasm Recurrence, Local - pathology | Neoplasms, Glandular and Epithelial - mortality | Aged, 80 and over | Adult | Female | Quinazolines - administration & dosage | Ovarian Neoplasms - drug therapy | Neoplasms, Glandular and Epithelial - pathology | Phthalazines - administration & dosage | Drug Administration Schedule | Risk Assessment | Kaplan-Meier Estimate | Treatment Outcome | Disease-Free Survival | Maximum Tolerated Dose | Antineoplastic Combined Chemotherapy Protocols - therapeutic use | Neoplasms, Glandular and Epithelial - drug therapy | Survival Analysis | Carcinoma, Ovarian Epithelial | Aged | Women | Antimitotic agents | Relapse | Oncology, Experimental | Research | Antineoplastic agents | Vascular endothelial growth factor | Sugars | Cancer | Diseases | Monosaccharides | Ovarian cancer | Index Medicus
Journal Article
Nature Communications, ISSN 2041-1723, 01/2014, Volume 5, Issue 1, pp. 2977 - 2977
Journal Article
by Song, Honglin and Song, Honglin and Dicks, Ed and Dicks, Ed and Ramus, Susan J and Ramus, Susan J and Tyrer, Jonathan P and Tyrer, Jonathan P and Intermaggio, Maria P and Intermaggio, Maria P and Hayward, Jane and Hayward, Jane and Edlund, Christopher K and Edlund, Christopher K and Conti, David and Conti, David and Harrington, Patricia and Harrington, Patricia and Fraser, Lindsay and Fraser, Lindsay and Philpott, Susan and Philpott, Susan and Anderson, Christopher and Anderson, Christopher and Rosenthal, Adam and Rosenthal, Adam and Gentry-Maharaj, Aleksandra and Gentry-Maharaj, Aleksandra and Bowtell, David D and Bowtell, David D and Alsop, Kathryn and Alsop, Kathryn and Cicek, Mine S and Cicek, Mine S and Cunningham, Julie M and Cunningham, Julie M and Fridley, Brooke L and Fridley, Brooke L and Alsop, Jennifer and Alsop, Jennifer and Jimenez-Linan, Mercedes and Jimenez-Linan, Mercedes and Høgdall, Estrid and Høgdall, Estrid and Høgdall, Claus K and Høgdall, Claus K and Jensen, Allan and Jensen, Allan and Kjaer, Susanne K.rüger and Kjaer, Susanne Krüger and Lubiński, Jan and Lubiński, Jan and Huzarski, Tomasz and Huzarski, Tomasz and Jakubowska, Anna and Jakubowska, Anna and Gronwald, Jacek and Gronwald, Jacek and Poblete, Samantha and Poblete, Samantha and Lele, Shashi and Lele, Shashi and Sucheston-Campbell, Lara and Sucheston-Campbell, Lara and Moysich, Kirsten B and Moysich, Kirsten B and Odunsi, Kunle and Odunsi, Kunle and Goode, Ellen L and Goode, Ellen L and Menon, Usha and Menon, Usha and Jacobs, Ian J and Jacobs, Ian J and Gayther, Simon A and Gayther, Simon A and Pharoah, Paul D. P and Pharoah, Paul D.P
Journal of Clinical Oncology, ISSN 0732-183X, 09/2015, Volume 33, Issue 26, pp. 2901 - 2907
Journal Article
Journal Article
Cancer Cell, ISSN 1535-6108, 09/2014, Volume 26, Issue 3, pp. 344 - 357
Journal Article
Cancer Research, ISSN 0008-5472, 12/2013, Volume 73, Issue 23, pp. 6900 - 6912
Journal Article