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Journal Article
Journal Article
Clinical Cancer Research, ISSN 1078-0432, 12/2012, Volume 18, Issue 24, pp. 6784 - 6791
Journal Article
The Journal of Pathology, ISSN 0022-3417, 07/2012, Volume 227, Issue 3, pp. 286 - 297
The current paradigm of cancer care relies on predictive nomograms which integrate detailed histopathology with clinical data. However, when predictions fail,... 
REST repressor | neuroendocrine prostate cancer | molecular pathology | massively parallel sequencing | chromothripsis | Massively parallel sequencing | Molecular pathology | Neuroendocrine prostate cancer | Chromothripsis | ANDROGEN RECEPTOR | CELLS | PREOPERATIVE NOMOGRAM | RADICAL PROSTATECTOMY | PATHOLOGY | GENE FUSIONS | ONCOLOGY | COMPARATIVE GENOMICS | RNA-SEQ | DISEASE RECURRENCE | EXPRESSION | POSTOPERATIVE NOMOGRAM | Neoplasms, Hormone-Dependent - metabolism | Prostatic Neoplasms - metabolism | Prognosis | Alternative Splicing | Oligonucleotide Array Sequence Analysis | Humans | Middle Aged | Gene Expression Regulation, Neoplastic | Male | Neoplasms, Hormone-Dependent - genetics | Patient Selection | Prostatic Neoplasms - therapy | Adenocarcinoma - metabolism | Neoplasm Grading | Prostatic Neoplasms - genetics | Transfection | RNA Interference | Cell Transformation, Neoplastic - genetics | Nomograms | Neuroendocrine Cells - metabolism | Adenocarcinoma - genetics | Precision Medicine | Prostatic Neoplasms - pathology | Genetic Predisposition to Disease | Neuroendocrine Cells - pathology | Decision Support Techniques | Gene Expression Profiling - methods | Gene Fusion | British Columbia | Gene Dosage | Lymphatic Metastasis | Cell Transformation, Neoplastic - metabolism | Adenocarcinoma - secondary | Prostate-Specific Antigen - blood | Biomarkers, Tumor - blood | Neoplasms, Hormone-Dependent - therapy | Phenotype | Adenocarcinoma - therapy | Neoplasms, Hormone-Dependent - pathology | Cell Line, Tumor | Aged | Biomarkers, Tumor - genetics | Cell Transformation, Neoplastic - pathology | Cluster Analysis
Journal Article
Lancet Oncology, The, ISSN 1470-2045, 2013, Volume 14, Issue 9, pp. 893 - 900
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2011, Volume 6, Issue 11, p. e27970
Background: Although androgens are depleted in castration resistant prostate cancer (CRPC), metastases still express nuclear androgen receptor (AR) and... 
SIGNAL | STEROIDOGENESIS | ACTIVATION | TESTOSTERONE | MULTIDISCIPLINARY SCIENCES | GENE-EXPRESSION | MECHANISMS | INDUCTION | BONE | PROGRESSION | GROWTH-FACTOR-I | Neoplasms, Hormone-Dependent - metabolism | Prostatic Neoplasms - metabolism | Prostatic Hyperplasia - pathology | Prognosis | Alternative Splicing | Humans | Middle Aged | Receptors, Androgen - metabolism | Gene Expression Regulation, Neoplastic | Bone Neoplasms - secondary | Male | Immunoenzyme Techniques | Prostate - metabolism | Bone Neoplasms - metabolism | Neoplasms, Hormone-Dependent - genetics | Prostate - pathology | Prostatic Neoplasms - genetics | Castration | Aged, 80 and over | Adult | Bone Neoplasms - genetics | Real-Time Polymerase Chain Reaction | Soft Tissue Neoplasms - genetics | Prostatic Neoplasms - pathology | Soft Tissue Neoplasms - secondary | RNA, Messenger - genetics | Soft Tissue Neoplasms - metabolism | Reverse Transcriptase Polymerase Chain Reaction | Prostatic Hyperplasia - genetics | Blotting, Western | Prostatic Hyperplasia - metabolism | Receptors, Androgen - genetics | Neoplasms, Hormone-Dependent - pathology | Cell Line, Tumor | Aged | Proteins | Viral antibodies | Antibodies | Androgens | Metastasis | Prostate cancer | Alternative splicing | Phosphorylation | Staining | Kinases | Tissues | Urology | Metastases | Angiogenesis | Xenografts | Localization | Medical research | Lymphatic system | Immunoglobulins | Review boards | C-Terminus | Gene expression | Polymerase chain reaction | Chemotherapy | Ligands | Immunoreactivity | Prostate | Cancer
Journal Article
Breast Cancer Research and Treatment, ISSN 0167-6806, 8/2014, Volume 147, Issue 1, pp. 211 - 219
The phosphatidylinositol-3-kinase pathway plays an important role in proliferation, migration and survival in breast cancer and may play a role in resistance... 
Resistance | Medicine & Public Health | PIK3CA | PTEN | Oncology | Endocrine | Breast cancer | Mutation | PTEN LOSS | ACTIVATION | BIOMARKER | SIGNATURE | GENE | ONCOLOGY | PATHWAY | ESTROGEN-RECEPTOR-ALPHA | EXPRESSION | CARCINOMA | CORRELATE | Neoplasms, Hormone-Dependent - mortality | Follow-Up Studies | Humans | Middle Aged | Neoplasms, Second Primary - mortality | Carcinoma, Intraductal, Noninfiltrating - genetics | Neoplasms, Hormone-Dependent - genetics | Neoplasm Recurrence, Local - pathology | Carcinoma, Ductal, Breast - drug therapy | Carcinoma, Lobular - genetics | Aged, 80 and over | Neoplasms, Second Primary - genetics | Carcinoma, Ductal, Breast - secondary | Carcinoma, Lobular - secondary | PTEN Phosphohydrolase - genetics | Survival Rate | Mutation - genetics | Adenocarcinoma - drug therapy | Breast Neoplasms - drug therapy | Adenocarcinoma - secondary | Disease Progression | Neoplasms, Second Primary - secondary | Breast Neoplasms - genetics | Class I Phosphatidylinositol 3-Kinases | Neoplasms, Second Primary - drug therapy | Cohort Studies | Carcinoma, Ductal, Breast - genetics | Prognosis | Neoplasm Recurrence, Local - drug therapy | Neoplasms, Hormone-Dependent - secondary | Neoplasm Recurrence, Local - mortality | Carcinoma, Ductal, Breast - mortality | Carcinoma, Intraductal, Noninfiltrating - mortality | Carcinoma, Lobular - mortality | Antineoplastic Agents, Hormonal - therapeutic use | Adult | Female | Adenocarcinoma - genetics | Neoplasm Invasiveness | Carcinoma, Intraductal, Noninfiltrating - drug therapy | Phosphatidylinositol 3-Kinases - genetics | Phosphatidylinositol 3-Kinase - genetics | Breast Neoplasms - pathology | Breast Neoplasms - mortality | Neoplasm Recurrence, Local - genetics | Aged | Carcinoma, Lobular - drug therapy | Neoplasms, Hormone-Dependent - drug therapy | Neoplasm Staging | Carcinoma, Intraductal, Noninfiltrating - secondary | Adenocarcinoma - mortality | Immunohistochemistry | Care and treatment | Relapse | Genetic aspects | Metastasis | Diseases | Development and progression
Journal Article