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Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 2008, Volume 75, Issue 2, pp. 484 - 493
Aldo-keto reductase (AKR) 1C3 (type 2 3α-HSD, type 5 17β-HSD, and prostaglandin F synthase) regulates ligand access to steroid hormone and prostaglandin... 
Prostaglandin metabolism | Inhibitor design | Steroid hormone metabolism | Cancer treatment | NSAIDs | Chemoprevention | cancer treatment | ANDROGEN RECEPTOR | SIGNALING PATHWAYS | INCREASED EXPRESSION | CRYSTAL-STRUCTURE | prostaglandin metabolism | 15-DEOXY-DELTA(12,14)-PROSTAGLANDIN J | PROLIFERATOR-ACTIVATED RECEPTOR | 3-ALPHA-HYDROXYSTEROID DEHYDROGENASE | chemoprevention | NONSTEROIDAL ANTIINFLAMMATORY DRUGS | ACID-BINDING PROTEIN | CYCLOOXYGENASE-2 INHIBITORS | inhibitor design | PHARMACOLOGY & PHARMACY | steroid hormone metabolism | Indomethacin - analogs & derivatives | Oxidation-Reduction | Humans | Enzyme Inhibitors - pharmacology | Hydroxyprostaglandin Dehydrogenases - metabolism | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | 3-Hydroxysteroid Dehydrogenases - antagonists & inhibitors | Hydroxyprostaglandin Dehydrogenases - antagonists & inhibitors | Melatonin - analogs & derivatives | Aldo-Keto Reductase Family 1 Member C3 | 3-Hydroxysteroid Dehydrogenases - metabolism | Indoles - pharmacology | Antineoplastic Agents - pharmacology | Catalysis | Neoplasms, Hormone-Dependent - drug therapy | Melatonin - pharmacology | Phenanthrenes - metabolism | Dihydrotestosterone - metabolism | Enzymes | Care and treatment | Synthetic prostaglandins F | Crystals | Hormones | Organic acids | Heterocyclic compounds | Physiological aspects | Glycols | Hormones, Sex | Indomethacin | Structure | Cancer
Journal Article
Breast Cancer Research, ISSN 1465-5411, 11/2013, Volume 15, Issue 6, pp. R114 - R114
Journal Article
Critical Reviews in Oncology and Hematology, ISSN 1040-8428, 2012, Volume 86, Issue 1, pp. 23 - 32
Journal Article
Biochemical Pharmacology, ISSN 0006-2952, 09/2017, Volume 140, pp. 1 - 7
[Display omitted] Steroid receptor coactivators (SRCs) are essential regulators of nuclear hormone receptor function. SRCs coactivate transcription mediated by... 
Transcription | Hormone-dependent cancer | Drug development | Coregulator | Steroid receptor coactivator | ANDROGEN RECEPTOR | ACTIVATION | AIB1 | CELL-PROLIFERATION | HISTONE ACETYLTRANSFERASE | TRANSCRIPTIONAL COACTIVATOR | BREAST-CANCER | STRUCTURAL BASIS | ESTROGEN | PHARMACOLOGY & PHARMACY | EXPRESSION | Neoplasms, Hormone-Dependent - metabolism | Drug Resistance, Multiple | Humans | Anti-Inflammatory Agents, Non-Steroidal - chemistry | Drug Resistance, Neoplasm | Neoplasm Proteins - antagonists & inhibitors | Antineoplastic Agents - therapeutic use | Nuclear Receptor Coactivator 1 - chemistry | Nuclear Receptor Coactivator 2 - metabolism | Molecular Targeted Therapy | Neoplasm Proteins - metabolism | Neoplasms, Hormone-Dependent - immunology | Nuclear Receptor Coactivator 2 - chemistry | Anti-Inflammatory Agents, Non-Steroidal - pharmacology | Nuclear Receptor Coactivator 1 - metabolism | Nuclear Receptor Coactivator 3 - chemistry | Drug Design | Anti-Inflammatory Agents - therapeutic use | Antineoplastic Agents - pharmacology | Protein Interaction Domains and Motifs | Nuclear Receptor Coactivator 3 - antagonists & inhibitors | Nuclear Receptor Coactivator 1 - antagonists & inhibitors | Anti-Inflammatory Agents - pharmacology | Neoplasm Proteins - chemistry | Antineoplastic Agents - chemistry | Anti-Inflammatory Agents - chemistry | Nuclear Receptor Coactivator 2 - antagonists & inhibitors | Anti-Inflammatory Agents, Non-Steroidal - therapeutic use | Nuclear Receptor Coactivator 3 - metabolism | Ligands | Neoplasms, Hormone-Dependent - drug therapy | Drugs | Medical colleges | Estrogen | DNA binding proteins | Metastasis | Chemotherapy | Epidermal growth factor | Interleukins | Methyltransferases | Pancreatic cancer | Physiological aspects | Progesterone | Drug therapy | Protein binding | Cancer
Journal Article