X
Search Filters
Format Format
Format Format
X
Sort by Item Count (A-Z)
Filter by Count
Journal Article (4377) 4377
Book Review (1709) 1709
Publication (419) 419
Book / eBook (112) 112
Book Chapter (47) 47
Conference Proceeding (15) 15
Web Resource (14) 14
Magazine Article (10) 10
Streaming Video (6) 6
Dissertation (1) 1
Presentation (1) 1
Trade Publication Article (1) 1
more...
Subjects Subjects
Subjects Subjects
X
Sort by Item Count (A-Z)
Filter by Count
humans (4199) 4199
index medicus (4173) 4173
female (1997) 1997
neoplastic syndromes, hereditary - genetics (1574) 1574
oncology (1496) 1496
male (1391) 1391
cancer (1336) 1336
gene expression regulation, neoplastic (1142) 1142
mutation (1136) 1136
adult (1044) 1044
middle aged (970) 970
animals (941) 941
genetic aspects (888) 888
genetic predisposition to disease (755) 755
tumors (753) 753
aged (671) 671
genetics & heredity (534) 534
neoplastic syndromes, hereditary - diagnosis (533) 533
research (524) 524
risk factors (506) 506
breast neoplasms - genetics (498) 498
cell transformation, neoplastic - genetics (494) 494
mice (481) 481
colorectal neoplasms - genetics (478) 478
pedigree (466) 466
pathology (453) 453
colorectal cancer (441) 441
mutations (436) 436
genes (427) 427
genetics (421) 421
neoplasms - genetics (412) 412
cell biology (394) 394
prognosis (391) 391
abridged index medicus (388) 388
genetic testing (382) 382
gene expression (371) 371
microsatellite instability (370) 370
phenotype (370) 370
risk (366) 366
expression (361) 361
cell transformation, neoplastic (339) 339
germ-line mutation (336) 336
analysis (335) 335
neoplastic syndromes, hereditary - pathology (332) 332
biochemistry & molecular biology (325) 325
breast cancer (323) 323
child (321) 321
signal transduction (317) 317
health aspects (315) 315
article (312) 312
adolescent (310) 310
immunohistochemistry (310) 310
surgery (309) 309
breast-cancer (297) 297
colorectal-cancer (296) 296
carcinoma (293) 293
gene (290) 290
medicine & public health (286) 286
dna methylation (278) 278
dna mutational analysis (278) 278
gastroenterology & hepatology (276) 276
cell line, tumor (267) 267
diagnosis (266) 266
gene mutations (264) 264
skin neoplasms - genetics (263) 263
ovarian neoplasms - genetics (262) 262
development and progression (255) 255
neoplastic syndromes, hereditary - epidemiology (250) 250
colorectal neoplasms, hereditary nonpolyposis - genetics (246) 246
aged, 80 and over (245) 245
neoplastic syndromes, hereditary (241) 241
neoplasm proteins - genetics (238) 238
proteins (238) 238
neoplasms (237) 237
germline mutations (229) 229
colorectal neoplasms - pathology (227) 227
medicine (226) 226
kidney neoplasms - genetics (224) 224
genes, tumor suppressor (223) 223
genetic counseling (214) 214
oncogenes (213) 213
cancer research (208) 208
colon-cancer (205) 205
carcinogenesis (204) 204
care and treatment (204) 204
research article (199) 199
cell transformation, neoplastic - pathology (197) 197
physiological aspects (190) 190
risk assessment (189) 189
cells (186) 186
apoptosis (185) 185
tumorigenesis (183) 183
disease progression (182) 182
genetic research (182) 182
tumor suppressor proteins - genetics (182) 182
biomarkers, tumor - genetics (181) 181
dna repair (181) 181
genes, brca1 (180) 180
multidisciplinary sciences (180) 180
dna (178) 178
more...
Library Location Library Location
Library Location Library Location
X
Sort by Item Count (A-Z)
Filter by Count
Gerstein Science - Stacks (81) 81
Online Resources - Online (14) 14
Sunnybrook Health Sciences Centre - Sunnybrook Stacks (9) 9
Collection Dvlpm't (Acquisitions) - Closed Orders (7) 7
UofT at Mississauga - Stacks (6) 6
Collection Dvlpm't (Acquisitions) - Vendor file (4) 4
St. Michael's Hospital - Stacks (3) 3
Sunnybrook Health Sciences Centre - Sunnybrook Reference (2) 2
Chemistry (A D Allen) - Stacks (1) 1
Gerstein Science - Circulation Desk (1) 1
Mt Sinai Hospital - Pathology (1) 1
Providence Healthcare - Withdrawn (1) 1
Scarborough Hospital - General (1) 1
St. Michael's Hospital - Circulation Desk (1) 1
St. Michael's Hospital - Online (1) 1
St. Michael's Hospital - Reference (1) 1
Toronto East General Hospital - Online (1) 1
UofT at Scarborough - Stacks (1) 1
more...
Language Language
Language Language
X
Sort by Item Count (A-Z)
Filter by Count
English (4240) 4240
German (79) 79
French (64) 64
Spanish (50) 50
Japanese (34) 34
Russian (17) 17
Czech (11) 11
Dutch (10) 10
Hungarian (10) 10
Italian (8) 8
Chinese (7) 7
Danish (5) 5
Polish (3) 3
Korean (2) 2
Portuguese (2) 2
Bulgarian (1) 1
Hebrew (1) 1
Slovak (1) 1
Turkish (1) 1
more...
Publication Date Publication Date
Click on a bar to filter by decade
Slide to change publication date range


Science, ISSN 0036-8075, 07/2017, Volume 357, Issue 6349, pp. 409 - 413
The genomes of cancers deficient in mismatch repair contain exceptionally high numbers of somatic mutations. In a proof-of-concept study, we previously showed... 
CELL LUNG-CANCER | SURVIVAL | COLORECTAL CARCINOMAS | RECEIVING NIVOLUMAB | IMMUNOTHERAPY | MICROSATELLITE INSTABILITY | MULTIDISCIPLINARY SCIENCES | LONG-TERM SAFETY | NEOANTIGENS | CHECKPOINT BLOCKADE | LYMPHOCYTES | Neoplastic Syndromes, Hereditary - immunology | Colorectal Neoplasms - genetics | Humans | Middle Aged | Male | Programmed Cell Death 1 Receptor - antagonists & inhibitors | Neoplastic Syndromes, Hereditary - mortality | Young Adult | Colorectal Neoplasms - therapy | Brain Neoplasms - immunology | DNA Mismatch Repair | Aged, 80 and over | Adult | Female | Neoplastic Syndromes, Hereditary - genetics | Brain Neoplasms - mortality | Biomarkers, Tumor - antagonists & inhibitors | Colorectal Neoplasms - mortality | Antibodies, Monoclonal, Humanized - therapeutic use | Antigens, Neoplasm - immunology | Brain Neoplasms - genetics | Disease-Free Survival | Colorectal Neoplasms - immunology | Cell Cycle Checkpoints - drug effects | Brain Neoplasms - therapy | Neoplastic Syndromes, Hereditary - therapy | T-Lymphocytes - immunology | Aged | Mutation | Programmed Cell Death 1 Receptor - immunology | Colorectal cancer | Genetic aspects | Nucleotide sequencing | Health aspects | DNA repair | Methods | Tumors | DNA sequencing | Yeast | PD-1 protein | Antibodies | Clinical trials | Genomes | Functional analysis | Lymphocytes T | Patients | Survival | Colon cancer | Immune checkpoint | Immunotherapy | Mismatch repair | Pancreatic cancer | Biomarkers | Bioindicators | Colon | Solid tumors | Genetic recombination | Repair | Cancer | Apoptosis | Index Medicus
Journal Article
Cancer, ISSN 0008-543X, 05/2017, Volume 123, Issue 10, pp. 1721 - 1730
Testing with a 25‐gene hereditary cancer panel more than doubled the number of women with a personal diagnosis of breast cancer identified as carrying a... 
hereditary breast and ovarian cancer | triple‐negative breast cancer | breast cancer type 1 | panel testing | ) | BRCA1 | BRCA2 | breast cancer type 1 (BRCA1) | triple-negative breast cancer | POPULATION | BRCA2 MUTATIONS | METAANALYSIS | VARIANTS | RISK | PREVALENCE | FAMILY-HISTORY | SUSCEPTIBILITY GENES | COWDEN-SYNDROME | ONCOLOGY | DIFFUSE GASTRIC-CANCER | Genetic Testing | Age Factors | Humans | Middle Aged | Young Adult | Checkpoint Kinase 2 - genetics | Tumor Suppressor Proteins - genetics | Aged, 80 and over | Genes, BRCA2 | Adult | Female | RNA Helicases - genetics | Lynch Syndrome II - genetics | Neoplastic Syndromes, Hereditary - genetics | Genes, BRCA1 | Nuclear Proteins - genetics | Fanconi Anemia Complementation Group N Protein | Hereditary Breast and Ovarian Cancer Syndrome - genetics | DNA-Binding Proteins - genetics | Fanconi Anemia Complementation Group Proteins | Breast Neoplasms - genetics | Triple Negative Breast Neoplasms - genetics | Aged | Ataxia Telangiectasia Mutated Proteins - genetics | Ubiquitin-Protein Ligases - genetics | Women | Breast cancer | Genetic aspects | Diagnosis | Research | Health aspects | Oncogenes | BRCA2 protein | CHK2 protein | Threonine | BRCA1 protein | Genes | Health risks | Protein C | Genetic screening | DNA helicase | Men | Breast | Ataxia | Ataxia telangiectasia mutated protein | Protein-serine/threonine kinase | Mutation | Health risk assessment | Age | Cancer | Index Medicus | Abridged Index Medicus
Journal Article
Gastroenterology, ISSN 0016-5085, 2014, Volume 146, Issue 3, pp. 643 - 646.e8
Journal Article
Journal of Medical Genetics, ISSN 0022-2593, 2010, Volume 47, Issue 7, pp. 436 - 444
Journal Article
Journal Article
Gastroenterology, ISSN 0016-5085, 2015, Volume 149, Issue 4, pp. 1017 - 1029.e3
Background & Aims Patients with bi-allelic germline mutations in mismatch repair (MMR) genes ( MLH1 , MSH2 , MSH6 , or PMS2 ) develop a rare but severe variant... 
Gastroenterology and Hepatology | Tumor | Colon Cancer | Predisposition | Functional Tests | SYSTEM | CELLS | BIALLELIC MUTATIONS | SOMATIC MUTATIONS | HEREDITARY | COLORECTAL-CANCER | PMS2 | MSH6 MUTATIONS | GASTROENTEROLOGY & HEPATOLOGY | GOLD STANDARD | NEUROFIBROMATOSIS TYPE-1 | MutL Protein Homolog 1 | Predictive Value of Tests | Colorectal Neoplasms - genetics | Colorectal Neoplasms, Hereditary Nonpolyposis - pathology | Humans | Drug Resistance, Neoplasm | Male | Neoplastic Syndromes, Hereditary - metabolism | Colorectal Neoplasms - diagnosis | Young Adult | DNA Mutational Analysis | Colorectal Neoplasms - drug therapy | Germ-Line Mutation | Mismatch Repair Endonuclease PMS2 | Neoplastic Syndromes, Hereditary - genetics | Caco-2 Cells | Lymphocytes - metabolism | Genetic Predisposition to Disease | Colorectal Neoplasms, Hereditary Nonpolyposis - drug therapy | Brain Neoplasms - diagnosis | HCT116 Cells | Brain Neoplasms - genetics | Neoplastic Syndromes, Hereditary - diagnosis | Heredity | MutS Homolog 2 Protein - genetics | Brain Neoplasms - drug therapy | Multiplex Polymerase Chain Reaction | Antineoplastic Agents, Alkylating - therapeutic use | Colorectal Neoplasms, Hereditary Nonpolyposis - metabolism | Phenotype | Adenosine Triphosphatases - genetics | Biomarkers, Tumor - genetics | Neoplastic Syndromes, Hereditary - drug therapy | Microsatellite Instability | Neoplastic Syndromes, Hereditary - pathology | Brain Neoplasms - pathology | DNA Repair Enzymes - genetics | Genetic Testing - methods | Brain Neoplasms - metabolism | Case-Control Studies | Transfection | Colorectal Neoplasms, Hereditary Nonpolyposis - diagnosis | Adult | Female | Nuclear Proteins - genetics | Colorectal Neoplasms - metabolism | Reproducibility of Results | Colorectal Neoplasms, Hereditary Nonpolyposis - genetics | DNA-Binding Proteins - genetics | Lymphocytes - drug effects | Adaptor Proteins, Signal Transducing - genetics | Colorectal Neoplasms - pathology | Methylation | Lymphomas | Diagnosis | Gene mutations | Lymphocytes | Leukemia | Colorectal cancer | Index Medicus | Abridged Index Medicus
Journal Article
International journal of cancer. Journal international du cancer, ISSN 0020-7136, 2012, Volume 131, Issue 2, pp. 367 - 376
Journal Article
Clinical Chemistry, ISSN 0009-9147, 2011, Volume 57, Issue 3, pp. 411 - 420
Journal Article