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by Shungin, Dmitry and Winkler, Thomas W and Croteau-Chonka, Damien C and Ferreira, Teresa and Locke, Adam E and Mägi, Reedik and Strawbridge, Rona J and Pers, Tune H and Fischer, Krista and Justice, Anne E and Workalemahu, Tsegaselassie and Wu, Joseph M. W and Buchkovich, Martin L and Heard-Costa, Nancy L and Roman, Tamara S and Drong, Alexander W and Song, Ci and Gustafsson, Stefan and Day, Felix R and Esko, Tonu and Fall, Tove and Kutalik, Zoltán and Luan, Jian’an and Randall, Joshua C and Scherag, André and Vedantam, Sailaja and Wood, Andrew R and Chen, Jin and Fehrmann, Rudolf and Karjalainen, Juha and Kahali, Bratati and Liu, Ching-Ti and Schmidt, Ellen M and Absher, Devin and Amin, Najaf and Anderson, Denise and Beekman, Marian and Bragg-Gresham, Jennifer L and Buyske, Steven and Demirkan, Ayse and Ehret, Georg B and Feitosa, Mary F and Goel, Anuj and Jackson, Anne U and Johnson, Toby and Kleber, Marcus E and Kristiansson, Kati and Mangino, Massimo and Mateo Leach, Irene and Medina-Gomez, Carolina and Palmer, Cameron D and Pasko, Dorota and Pechlivanis, Sonali and Peters, Marjolein J and Prokopenko, Inga and Stančáková, Alena and Ju Sung, Yun and Tanaka, Toshiko and Teumer, Alexander and Van Vliet-Ostaptchouk, Jana V and Yengo, Loïc and Zhang, Weihua and Albrecht, Eva and Ärnlöv, Johan and Arscott, Gillian M and Bandinelli, Stefania and Barrett, Amy and Bellis, Claire and Bennett, Amanda J and Berne, Christian and Blüher, Matthias and Böhringer, Stefan and Bonnet, Fabrice and Böttcher, Yvonne and Bruinenberg, Marcel and Carba, Delia B and Caspersen, Ida H and Clarke, Robert and Warwick Daw, E and Deelen, Joris and Deelman, Ewa and Delgado, Graciela and Doney, Alex S. F and Eklund, Niina and Erdos, Michael R and Estrada, Karol and Eury, Elodie and Friedrich, Nele and Garcia, Melissa E and Giedraitis, Vilmantas and Gigante, Bruna and Go, Alan S and Golay, Alain and Grallert, Harald and Grammer, Tanja B and Gräßler, Jürgen and Grewal, Jagvir and Groves, Christopher J and Haller, Toomas and Hallmans, Goran and ... and The PAGE Consortium and The International Endogene Consortium and The MAGIC Investigators and The ReproGen Consortium and The CKDGen Consortium and The ADIPOGen Consortium and The ICBP and The CARDIOGRAMplusC4D Consortium and The GENIE Consortium and The GLGC and The GEFOS Consortium and The MuTHER Consortium and The LifeLines Cohort Study and PAGE Consortium and LifeLines Cohort Study and CARDIOGRAMplusC4D Consortium and MuTHER Consortium and ICBP and ADIPOGEN Consortium and CKDGen Consortium and GEFOS Consortium and Int Endogene Consortium and GENIE Consortium and MAGIC Investigators and ReproGen Consortium and GLGC and ADIPOGen Consortium and International Endogene Consortium and Göteborgs universitet and Gothenburg University and Institutionen för medicin, avdelningen för invärtesmedicin och klinisk nutrition and Sahlgrenska Academy and Centre for Bone and Arthritis Research and Sahlgrenska akademin and Institute of Medicine, Department of Internal Medicine and Clinical Nutrition
Nature (London), ISSN 1476-4687, 2015, Volume 518, Issue 7538, pp. 187 - 196
.... To increase our understanding of the genetic basis of body fat distribution and its molecular links to cardiometabolic traits, here we conduct genome-wide association meta-analyses of traits related... 
no | ABDOMINAL ADIPOSITY | METAANALYSIS | VARIANTS | MULTIDISCIPLINARY SCIENCES | COMMON SNPS | GLYCEMIC TRAITS | RISK | FALSE DISCOVERY | GENOME-WIDE ASSOCIATION | ADIPOGENIC DIFFERENTIATION | SEXUAL-DIMORPHISM | Body Mass Index | Genome-Wide Association Study | Age Factors | Neovascularization, Physiologic - genetics | Epigenesis, Genetic | Humans | Male | Continental Population Groups - genetics | Sex Characteristics | Obesity - genetics | Europe - ethnology | Genome, Human - genetics | Adipose Tissue - metabolism | Insulin - metabolism | Models, Biological | Adipocytes - metabolism | Insulin Resistance - genetics | Polymorphism, Single Nucleotide - genetics | Female | Body Fat Distribution | Transcription, Genetic - genetics | Adipogenesis - genetics | Waist-Hip Ratio | Quantitative Trait Loci - genetics | Adipose tissues | Quantitative trait loci | Genetic research | Genetic aspects | Research | Metabolism | Health aspects | Studies | Body mass index | Genealogy | Body fat | Insulin resistance | Genetics | Genomes | Abdomen | Meta-analysis | Life Sciences | Adipocytes/metabolism Adipogenesis/genetics Adipose Tissue/metabolism Age Factors Body Fat Distribution Body Mass Index Continental Population Groups/genetics Epigenesis, Genetic Europe/ethnology Female Genome, Human/genetics Genome-Wide Association Study Humans Insulin/metabolism Insulin Resistance/genetics Male Models, Biological Neovascularization, Physiologic/genetics Obesity/genetics Polymorphism, Single Nucleotide/genetics Quantitative Trait Loci/genetics Sex Characteristics Transcription, Genetic/genetics Waist-Hip Ratio | Folkhälsovetenskap, global hälsa, socialmedicin och epidemiologi | Endokrinologi och diabetes | Public Health, Global Health, Social Medicine and Epidemiology | Endocrinology and Diabetes
Journal Article
Journal of applied physiology (1985), ISSN 1522-1601, 2012, Volume 113, Issue 8, pp. 1253 - 1259
Pregnancy is associated with ventricular hypertrophy and volume overload. Here we investigated whether late pregnancy is associated with cardiac structural and... 
Pregnancy | Angiogenesis | Fibrosis | Hypertrophy | MYOCARDIUM | OVERLOAD | SPORT SCIENCES | PHYSIOLOGY | RAT | hypertrophy | angiogenesis | pregnancy | MATRIX METALLOPROTEINASE-2 | DILATED CARDIOMYOPATHY | OSTEOPONTIN | fibrosis | EXTRACELLULAR-MATRIX | EXPRESSION | Osteopontin - genetics | Pregnancy Complications, Cardiovascular - physiopathology | Matrix Metalloproteinases - genetics | Blood Pressure - genetics | Echocardiography - methods | Postpartum Period - physiology | Osteopontin - metabolism | Pregnancy Complications, Cardiovascular - genetics | Vascular Endothelial Growth Factor A - metabolism | Fibrosis - metabolism | Vascular Endothelial Growth Factor A - genetics | Disintegrins - genetics | Pregnancy Complications, Cardiovascular - metabolism | Postpartum Period - metabolism | Myocardium - metabolism | Female | Neovascularization, Pathologic - physiopathology | Blood Pressure - physiology | Postpartum Period - genetics | Fibrosis - genetics | Disintegrins - metabolism | Fibrosis - physiopathology | Mice, Inbred C57BL | Cardiomegaly - physiopathology | Myocardium - pathology | Up-Regulation - genetics | Down-Regulation - genetics | Animals | Heart Ventricles - physiopathology | Neovascularization, Pathologic - genetics | Heart Ventricles - metabolism | Mice | Neovascularization, Pathologic - metabolism | Hemodynamics | Matrix Metalloproteinases - metabolism | Cardiomegaly - genetics | Cardiomegaly - metabolism
Journal Article
American Journal of Physiology - Endocrinology And Metabolism, ISSN 0193-1849, 10/2012, Volume 303, Issue 7, pp. 832 - 840
Changes in adipose tissue metabolism are central to adaptation of whole body energy homeostasis to pregnancy. To gain insight into the molecular mechanisms... 
DIABETES-MELLITUS | PHYSIOLOGY | LIPID-METABOLISM | MASS DEPOSITION | TRANSCRIPTION FACTOR FOXO1 | INSULIN-RESISTANCE | ENDOCRINOLOGY & METABOLISM | SERUM-AMYLOID-A | LONGITUDINAL CHANGES | LATE-GESTATION | ADIPOCYTE DIFFERENTIATION | BODY-COMPOSITION | Adaptation, Physiological | Antigens, CD - immunology | Adipose Tissue - physiology | Antigens, CD - biosynthesis | Humans | NF-kappa B - immunology | Pregnancy Trimester, Third - genetics | NF-kappa B - metabolism | Transcriptome - immunology | Adipose Tissue - immunology | Lipid Metabolism - immunology | Signal Transduction - immunology | Adipokines - genetics | Female | Lipid Metabolism - genetics | Pregnancy Trimester, First - physiology | Transcriptome - physiology | Antigens, Differentiation, Myelomonocytic - immunology | Chemokines - immunology | Lipopolysaccharide Receptors - biosynthesis | Antigens, Differentiation, Myelomonocytic - biosynthesis | Pregnancy Trimester, Third - physiology | Neovascularization, Physiologic - genetics | Pregnancy Trimester, First - immunology | Lipopolysaccharide Receptors - immunology | Adipokines - immunology | Adipokines - metabolism | Inflammation - immunology | Pregnancy Trimester, Third - immunology | Signal Transduction - genetics | Toll-Like Receptor 4 - immunology | Transcriptome - genetics | Chemokines - genetics | Neovascularization, Physiologic - immunology | Toll-Like Receptor 4 - metabolism | Pregnancy | Receptor, IGF Type 2 - immunology | Pregnancy Trimester, First - genetics | Inflammation - genetics | Signal Transduction - physiology | Chemokines - metabolism | Receptor, IGF Type 2 - biosynthesis | Lipid Metabolism - physiology | Inflammation - physiopathology | Adipose tissues | Physiological aspects | Development and progression | Inflammation | Research | Molecular biology | Health aspects
Journal Article
Circulation (New York, N.Y.), ISSN 1524-4539, 2019, Volume 139, Issue 22, pp. 2570 - 2584
.... The expansion of the cardiac vasculature, to maintain adequate supply of oxygen and nutrients, is a key determinant of whether the heart grows in a physiological compensated manner or a pathological... 
HB-EGF | hypertrophy | VEGF-B | angiogenesis | VEGFR-1 | CARDIAC & CARDIOVASCULAR SYSTEMS | CARDIAC GROWTH | VEGF | REGENERATION | HEART-FAILURE | RECEPTOR | ADAM12 | PERIPHERAL VASCULAR DISEASE | ANGIOCRINE SIGNALS | Receptors, Notch - metabolism | Humans | Cardiomegaly - pathology | Vascular Endothelial Growth Factor Receptor-2 - genetics | Disease Models, Animal | Vascular Endothelial Growth Factor Receptor-1 - genetics | ErbB Receptors - metabolism | Receptor Cross-Talk | Paracrine Communication | Signal Transduction | Endothelial Cells - metabolism | Mice, Inbred C57BL | Cells, Cultured | Cardiomegaly - physiopathology | Vascular Endothelial Growth Factor Receptor-2 - metabolism | Vascular Endothelial Growth Factor Receptor-1 - metabolism | Mice, Knockout | Heparin-binding EGF-like Growth Factor - metabolism | Myocytes, Cardiac - pathology | Animals | Vascular Endothelial Growth Factor B - metabolism | Myocytes, Cardiac - metabolism | Endothelial Cells - pathology | Neovascularization, Physiologic | Cardiomegaly - metabolism | Heart failure | Cell interaction | Care and treatment | Heart cells | Physiological aspects | Development and progression | Genetic aspects | Cellular signal transduction | Health aspects | Vascular endothelial growth factor | Endothelium | 10011 | 10054 | 10037 | 10014 | Original s | 10028
Journal Article
PloS one, ISSN 1932-6203, 2010, Volume 5, Issue 7, p. e11822
Background: Angiogenesis plays an important role in a wide range of physiological processes, and many diseases are associated with the dysregulation of angiogenesis... 
BREAST-CANCER | CELLS | IN-VITRO | CHINESE HERBAL DECOCTION | MULTIDISCIPLINARY SCIENCES | RADIX ANGELICAE SINENSIS | ASTRAGALI | NITRIC-OXIDE | BIOLOGICAL ASSESSMENT | CORONARY-ARTERY | ENDOTHELIAL GROWTH-FACTOR | Protein Binding - genetics | Receptors, Estrogen - metabolism | Humans | Isoflavones - metabolism | Estrogen Receptor beta - metabolism | Isoflavones - genetics | Estrogen Receptor beta - genetics | Polymerase Chain Reaction | Estrogen Receptor alpha - metabolism | Umbilical Veins - cytology | Receptors, Estrogen - genetics | Animals, Genetically Modified | Endothelial Cells - metabolism | Neovascularization, Physiologic - genetics | Zebrafish | Signal Transduction - genetics | Blotting, Western | Neovascularization, Physiologic - physiology | Animals | Estrogen Receptor alpha - genetics | Endothelial Cells - cytology | Mitogen-Activated Protein Kinases - genetics | Signal Transduction - physiology | Mitogen-Activated Protein Kinases - metabolism | Protein Binding - physiology | Medicinal plants | Tyrosine | Medical research | Embryonic development | Estrogen | Animal genetic engineering | Endothelium | Analysis | Medicine, Botanic | Physiological aspects | Medicine, Experimental | Phenols | Genetic research | Medicine, Herbal | Vascular endothelial growth factor | Mitogens | Protein kinases | Biotechnology | Estrogens | Transgenic | Estrogen receptors | Kinases | Modulators | Western blotting | Cell adhesion & migration | Angiogenesis | Signal transduction | Receptors | Rodents | Protein-tyrosine kinase | Binding | Extracellular signal-regulated kinase | MAP kinase | Tamoxifen | Gene expression | Embryos | Endothelial cells | Vascular endothelial growth factor receptors | Herbal medicine | Signaling | Nitric oxide | In vivo methods and tests | Raloxifene | Selective estrogen receptor modulators | In vitro methods and tests | Umbilical vein
Journal Article