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The New England Journal of Medicine, ISSN 0028-4793, 07/2010, Volume 363, Issue 4, pp. 343 - 354
This study compared the conformation of the antibody epitopes in Goodpasture's disease and Alport's post-transplantation nephritis in search of the... 
MEDICINE, GENERAL & INTERNAL | BASEMENT-MEMBRANE ANTIBODY | ALPHA-3 CHAIN | NONCOLLAGENOUS DOMAIN | IV COLLAGEN | IMMUNE PRIVILEGE | GRAVES-DISEASE | CRYPTIC EPITOPES | NC1 DOMAIN | RENAL-TRANSPLANTATION | ALPORT-SYNDROME | Epitope Mapping | Autoantibodies - metabolism | Epitopes - metabolism | Antibodies - chemistry | Autoantibodies - chemistry | Humans | Middle Aged | Male | Postoperative Complications - immunology | Collagen Type IV - chemistry | Young Adult | Anti-Glomerular Basement Membrane Disease - immunology | Nephritis - immunology | Aged, 80 and over | Adult | Female | Retrospective Studies | Collagen Type IV - immunology | Isoantibodies - chemistry | Isoantibodies - metabolism | Collagen Type IV - metabolism | Nephritis, Hereditary - immunology | Enzyme-Linked Immunosorbent Assay | Autoantigens - blood | Autoantigens - chemistry | Autoantibodies - immunology | Nephritis, Hereditary - surgery | Protein Isoforms | Glomerular Basement Membrane - immunology | Antibodies - blood | Protein Conformation | Aged | Epitopes - chemistry | Kidney Glomerulus - immunology | Binding Sites, Antibody | Kidney Transplantation - immunology | Proteins | Medical research | Transplants & implants | Laboratory animals | Collagen | Urologi och njurmedicin | Clinical Medicine | Medical and Health Sciences | Klinisk medicin | Medicin och hälsovetenskap | Urology and Nephrology
Journal Article
Kidney International, ISSN 0085-2538, 04/2013, Volume 83, Issue 4, pp. 662 - 673
Proteinuria is an independent risk factor for progressive renal diseases because it initiates or aggravates tubulointerstitial injury. Clinically, females are... 
β-oxidation | mitochondrial stress | free fatty acid | inflammasome | CELLS | APOPTOSIS | ACTIVATION | RALOXIFENE | ENDOPLASMIC-RETICULUM STRESS | PALMITATE | 17-BETA-ESTRADIOL | beta-oxidation | INFLAMMATION | UROLOGY & NEPHROLOGY | ALBUMIN | EXPRESSION | Raloxifene Hydrochloride - pharmacology | Nephritis, Hereditary - pathology | Apoptosis - drug effects | Humans | NF-kappa B - metabolism | Mitochondria - immunology | Proteinuria - pathology | Glomerulonephritis - metabolism | Atrophy | Inflammasomes - drug effects | Inflammation Mediators - metabolism | Lipid Peroxidation - drug effects | Female | Macrophages - immunology | Disease Models, Animal | Nephritis, Hereditary - immunology | Kidney Tubules, Proximal - immunology | Kidney Tubules, Proximal - pathology | Cytokines - metabolism | Ovariectomy | Oxidation-Reduction | Proteinuria - immunology | Cells, Cultured | Gene Expression Regulation | Glomerulonephritis - genetics | Nephritis, Hereditary - genetics | Proteinuria - metabolism | Glomerulonephritis - immunology | Mitochondria - metabolism | Mitochondria - drug effects | Mitochondria - pathology | Proteinuria - genetics | Mice, Inbred ICR | Glomerulonephritis - drug therapy | Animals | Nephritis, Hereditary - metabolism | Proteinuria - drug therapy | Glomerulonephritis - pathology | Inflammasomes - immunology | Fibrosis | Kidney Tubules, Proximal - metabolism | Macrophages - drug effects | Mice | Nephritis, Hereditary - drug therapy | Oxidative Stress - drug effects | Selective Estrogen Receptor Modulators - pharmacology | Kidney Tubules, Proximal - drug effects
Journal Article
Journal Article
Matrix Biology, ISSN 0945-053X, 01/2017, Volume 57-58, pp. 334 - 346
The outcome of tissue engineered organ transplants depends on the capacity of the biomaterial to promote a pro-healing response once implanted in vivo.... 
Cell–matrix interactions | Macrophages | Renal extracellular matrix scaffolds (ECM) | COLONY-STIMULATING FACTOR | BIOCHEMISTRY & MOLECULAR BIOLOGY | PORCINE KIDNEYS | SOLUBILIZED EXTRACELLULAR-MATRIX | MODEL | POLYPROPYLENE MESH | CELL BIOLOGY | Cell-matrix interactions | REGENERATIVE MEDICINE | GROWTH-FACTOR | SCAFFOLDS | CHRONIC KIDNEY-DISEASE | DECELLULARIZED RAT | Immunohistochemistry | Nephritis, Hereditary - pathology | Humans | Collagen Type I - chemistry | Extracellular Matrix - immunology | Kidney - immunology | Extracellular Matrix - chemistry | Tissue Scaffolds | Macrophages - immunology | Disease Models, Animal | Nephritis, Hereditary - immunology | Macrophages - classification | Tissue Engineering - methods | Anti-Inflammatory Agents - pharmacology | Mice, Inbred C57BL | Immunophenotyping | Macrophages - cytology | Polyesters - pharmacology | Polyesters - chemistry | Extracellular Matrix - ultrastructure | Phenotype | Animals | Anti-Inflammatory Agents - chemistry | Nephritis, Hereditary - metabolism | Kidney - chemistry | Macrophages - drug effects | Collagen Type I - pharmacology | Mice | Primary Cell Culture | Macrophage Activation - drug effects | Cytokines - biosynthesis | Transplantation of organs, tissues, etc | Biological products | Tissue engineering | Collagen | cell-matrix interactions | renal extracellular matrix scaffolds (ECM) | macrophages
Journal Article
Journal Article
PLoS ONE, ISSN 1932-6203, 11/2015, Volume 10, Issue 11, p. e0141231
Alport syndrome is a genetic disease of collagen IV (alpha 3, 4, 5) resulting in renal failure. This study was designed to investigate sex-phenotype... 
FIBROSIS | CELLS | COLLAGEN | DELAYS RENAL-FAILURE | MULTIDISCIPLINARY SCIENCES | MOUSE MODEL | IN-VIVO | INJURY | MYOFIBROBLASTS | BLOCKADE | HEREDITARY NEPHROPATHY | Clodronic Acid - pharmacology | Kidney - pathology | Male | Mice, 129 Strain | Autoantigens - genetics | Female | Models, Animal | Nephritis, Hereditary - physiopathology | Drug Evaluation, Preclinical | Nephritis, Hereditary - immunology | Macrophages - pathology | Nephritis, Hereditary - genetics | Sex Characteristics | Disease Progression | Mice, Knockout | Animals | Collagen Type IV - deficiency | Clodronic Acid - therapeutic use | Collagen Type IV - genetics | Macrophages - drug effects | Clodronic Acid - administration & dosage | Mice | Nephritis, Hereditary - drug therapy | Liposomes | Apoptosis | Kidney Failure, Chronic - etiology | Medical research | Care and treatment | Phenotype | Sex factors in disease | Medicine, Experimental | Development and progression | Alport's syndrome | Research | Identification and classification | Biomedical research | Syngeneic grafts | Medical services | Sex | Macrophages | Bisphosphonates | Recruitment | Rodents | Gender aspects | Collagen (type IV) | Bioindicators | Age | Failure | Urine | Medical treatment | Sex differences | Clodronic acid | Studies | Pathology | Depletion | Life span | Body mass | Correlation analysis | Collagen | Fibrosis | Alport syndrome | Renal failure | Biomarkers | Infiltration | Mutation | Kidney diseases | Kidney transplantation
Journal Article
Blood, ISSN 0006-4971, 11/2011, Volume 118, Issue 22, pp. 5862 - 5871
Journal Article
ANNALS OF CLINICAL AND LABORATORY SCIENCE, ISSN 0091-7370, 09/2017, Volume 47, Issue 5, pp. 620 - 624
Journal Article